KR870008026A - 인체 비소형세포 폐암 및 기타 인체암 치료용 모노클로날항체 및 항원 - Google Patents

인체 비소형세포 폐암 및 기타 인체암 치료용 모노클로날항체 및 항원 Download PDF

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Publication number
KR870008026A
KR870008026A KR870001623A KR870001623A KR870008026A KR 870008026 A KR870008026 A KR 870008026A KR 870001623 A KR870001623 A KR 870001623A KR 870001623 A KR870001623 A KR 870001623A KR 870008026 A KR870008026 A KR 870008026A
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KR
South Korea
Prior art keywords
cells
monoclonal antibody
lung cancer
human
small cell
Prior art date
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Granted
Application number
KR870001623A
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English (en)
Korean (ko)
Inventor
에리크 헬스트롬 칼
피. 브라운 조세프
헬스트롬 인게거드
마르크바르트 한스
Original Assignee
브래들리 더블유. 시몬스
온코겐, 어 리미티드 파트너쉽
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Application filed by 브래들리 더블유. 시몬스, 온코겐, 어 리미티드 파트너쉽 filed Critical 브래들리 더블유. 시몬스
Publication of KR870008026A publication Critical patent/KR870008026A/ko
Granted legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
KR870001623A 1986-02-26 1987-02-25 인체 비소형세포 폐암 및 기타 인체암 치료용 모노클로날항체 및 항원 Granted KR870008026A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US834,172 1986-02-26
US06/834,172 US5185432A (en) 1986-02-26 1986-02-26 Monoclonal antibodies and antigen for human non-small cell lung carcinoma and other certain human carcinomas

Publications (1)

Publication Number Publication Date
KR870008026A true KR870008026A (ko) 1987-09-23

Family

ID=25266276

Family Applications (2)

Application Number Title Priority Date Filing Date
KR870001623A Granted KR870008026A (ko) 1986-02-26 1987-02-25 인체 비소형세포 폐암 및 기타 인체암 치료용 모노클로날항체 및 항원
KR1019870001623A Expired KR900006338B1 (ko) 1986-02-26 1987-02-25 인체 비소형세포 폐암 및 기타 인체암 치료용 모노클로날 항체 및 항원

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019870001623A Expired KR900006338B1 (ko) 1986-02-26 1987-02-25 인체 비소형세포 폐암 및 기타 인체암 치료용 모노클로날 항체 및 항원

Country Status (28)

Country Link
US (1) US5185432A (https=)
JP (1) JPS62220197A (https=)
KR (2) KR870008026A (https=)
CN (1) CN87100927A (https=)
AT (1) AT400577B (https=)
AU (1) AU612967B2 (https=)
BE (1) BE1000611A5 (https=)
CA (1) CA1312025C (https=)
CH (1) CH675880A5 (https=)
DD (2) DD276165A5 (https=)
DE (1) DE3705276A1 (https=)
DK (1) DK98187A (https=)
ES (1) ES2004245A6 (https=)
FI (1) FI870764A7 (https=)
FR (1) FR2596062B1 (https=)
GB (1) GB2186885B (https=)
GR (1) GR870294B (https=)
IE (1) IE60286B1 (https=)
IT (1) IT1203511B (https=)
LU (1) LU86786A1 (https=)
NL (1) NL8700415A (https=)
NO (1) NO174719C (https=)
NZ (1) NZ219338A (https=)
OA (1) OA08485A (https=)
PT (1) PT84370B (https=)
SE (2) SE467988B (https=)
YU (1) YU46189B (https=)
ZA (1) ZA869494B (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531301A1 (de) * 1985-09-02 1987-03-05 Behringwerke Ag Monoklonale antikoerper gegen tumorassoziierte glykoproteine, verfahren zu ihrer herstellung sowie ihre verwendung
JPH0813840B2 (ja) * 1987-03-31 1996-02-14 協和醗酵工業株式会社 抗ヒト肺腺癌単クロ−ン性抗体
US5134075A (en) * 1989-02-17 1992-07-28 Oncogen Limited Partnership Monoclonal antibody to novel antigen associated with human tumors
US5171665A (en) * 1989-04-17 1992-12-15 Oncogen Monoclonal antibody to novel antigen associated with human tumors
US5342774A (en) * 1991-05-23 1994-08-30 Ludwig Institute For Cancer Research Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1
US5589579A (en) * 1994-07-19 1996-12-31 Cytoclonal Pharmaceutics, Inc. Gene sequence and probe for a marker of non-small cell lung carinoma
EP0863402B1 (en) 1997-03-03 2005-09-14 Amersham Biosciences UK Limited In-situ cell extraction and assay method
DE19725133A1 (de) * 1997-06-13 1998-12-17 Micromet Ges Fuer Biomedizinis Nachweis von seltenen Zellen
US20050089918A1 (en) * 1998-02-23 2005-04-28 Amersham Biosciences Uk Limited In-situ cell extraction and assay method
US6117981A (en) * 1999-06-03 2000-09-12 Cytoclonal Pharmaceutics, Inc. Hybridomas for lung cancer marker and monoclonal antibodies thereof
CA2389916A1 (en) * 1999-09-03 2001-03-15 Human Genome Sciences, Inc. B7-like polynucleotides, polypeptides, and antibodies
CA2412377A1 (en) 2000-06-06 2001-12-13 Bristol-Myers Squibb Company B7-related nucleic acids and polypeptides and their uses for immunomodulation
TWI317285B (en) * 2000-07-28 2009-11-21 Dainippon Sumitomo Pharma Co New use and kit for remedies for cancer
CN101724072B (zh) * 2008-10-27 2013-10-09 谷为岳 一种抗肿瘤的单克隆抗体的序列及应用
GB0916686D0 (en) * 2009-09-23 2009-11-04 Univ Manchester Metropolitan Treatment of cancer
PH12012501751A1 (en) 2010-03-04 2012-11-12 Macrogenics Inc Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
JP5998060B2 (ja) 2010-03-04 2016-09-28 マクロジェニクス，インコーポレーテッド Ｂ７−ｈ３と反応性のある抗体、その免疫学的に活性なフラグメントおよびその使用
EP2617730B1 (en) * 2010-09-17 2018-03-07 National Institute of Advanced Industrial Science And Technology Lung cancer differential marker
CN102391992B (zh) * 2011-11-03 2012-08-29 潘世扬 抗人非小细胞肺癌单克隆抗体及其应用
TWI781098B (zh) 2016-04-15 2022-10-21 美商宏觀基因股份有限公司 新穎的ｂ７-ｈ３-結合分子、其抗體藥物綴合物及其使用方法
CN111662371B (zh) * 2020-04-30 2023-07-04 美康生物科技股份有限公司 细胞角蛋白19片段抗原及其制备方法和应用
CN112300284B (zh) * 2020-12-29 2021-04-06 慈达(广州)生物技术有限公司 核酸筛选结合抗体检测用于癌症检测中的用途及其制备的试剂盒

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569788A (en) * 1983-05-18 1986-02-11 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibodies against non small cell lung cancer
IL76877A (en) * 1984-11-02 1991-11-21 Oncogen Diagnostic method for the determination of human non-small cell lung carcinomas employing novel monoclonal antibodies and compositions containing said antibodies
ZA858371B (en) * 1984-11-02 1987-03-25 Oncogen Monoclonal antibodies for human non-small cell lung carcinomas

Also Published As

Publication number Publication date
AU612967B2 (en) 1991-07-25
SE9201529D0 (sv) 1992-05-14
AT400577B (de) 1996-01-25
CN87100927A (zh) 1988-10-05
DK98187D0 (da) 1987-02-25
SE467988B (sv) 1992-10-12
IT8719491A0 (it) 1987-02-25
GB8703700D0 (en) 1987-03-25
FR2596062B1 (fr) 1990-06-08
DD266028A5 (de) 1989-03-22
IE60286B1 (en) 1994-06-29
IT1203511B (it) 1989-02-15
KR880010438A (ko) 1988-10-08
NL8700415A (nl) 1987-09-16
ATA43587A (de) 1995-06-15
SE9201529A0 (sv) 1992-05-14
NO870770D0 (no) 1987-02-25
GB2186885B (en) 1990-10-03
NO174719B (no) 1994-03-14
FI870764A0 (fi) 1987-02-23
YU46189B (sh) 1993-05-28
DD276165A5 (de) 1990-02-14
US5185432A (en) 1993-02-09
FR2596062A1 (fr) 1987-09-25
CH675880A5 (https=) 1990-11-15
CA1312025C (en) 1992-12-29
SE8700805L (sv) 1987-10-22
NO870770L (no) 1987-08-27
KR900006338B1 (ko) 1990-08-28
DE3705276A1 (de) 1987-08-27
GR870294B (en) 1987-06-30
BE1000611A5 (fr) 1989-02-21
NZ219338A (en) 1991-11-26
IE870487L (en) 1987-08-26
LU86786A1 (fr) 1987-09-15
PT84370A (en) 1987-03-01
ES2004245A6 (es) 1988-12-16
SE8700805D0 (sv) 1987-02-25
DK98187A (da) 1987-08-27
FI870764A7 (fi) 1987-08-27
GB2186885A (en) 1987-08-26
YU25787A (en) 1990-12-31
PT84370B (pt) 1989-11-10
AU6927287A (en) 1987-08-27
JPS62220197A (ja) 1987-09-28
ZA869494B (en) 1987-10-28
OA08485A (fr) 1988-07-29
NO174719C (no) 1994-06-22

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