KR870002131A - 신규한 벤조디옥세판 및 그것의 제조 방법 - Google Patents

신규한 벤조디옥세판 및 그것의 제조 방법 Download PDF

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Publication number
KR870002131A
KR870002131A KR1019860006588A KR860006588A KR870002131A KR 870002131 A KR870002131 A KR 870002131A KR 1019860006588 A KR1019860006588 A KR 1019860006588A KR 860006588 A KR860006588 A KR 860006588A KR 870002131 A KR870002131 A KR 870002131A
Authority
KR
South Korea
Prior art keywords
benzodioxepan
compound according
carboxylic acid
benzodioxepane
cyclohexenylmethyl
Prior art date
Application number
KR1019860006588A
Other languages
English (en)
Other versions
KR920006238B1 (ko
Inventor
베산콘 데니스
프랑쎄쉬니 재클린
Original Assignee
원본미기재
쏘시에떼 데뛰드 시앙띠휘끄 에 앵뒤스트리엘드 일-드-프랑스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 원본미기재, 쏘시에떼 데뛰드 시앙띠휘끄 에 앵뒤스트리엘드 일-드-프랑스 filed Critical 원본미기재
Publication of KR870002131A publication Critical patent/KR870002131A/ko
Application granted granted Critical
Publication of KR920006238B1 publication Critical patent/KR920006238B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems

Abstract

내용 없음

Description

신규한 벤조디옥세판 및 그것의 제조 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. N-(1-사이클로헥세닐메틸 2-피롤리디닐메틸) 8-에틸설포닐 1,5-벤조디옥세판 6-카복스아미드 및 그것의 생리학적으로 허영가능한 염.
  2. 1,5-벤조디옥세판 6-카복실산을 8-클로로설포닐 1,5-벤조디옥세판 6-카복실산을 얻기 위해 설푸릭 클로로히드린으로 처리하고, 후자를 중탄산 나트륨 및 아황산 나트륨으로 다음에는 요오드화 에틸로 처리하고 얻은 8-에틸설포닐 1,5-벤조디옥세판 6-카복실산을 염화 티오닐로 처리하고 결과의 산 염화물을 1-(1-사이클로헥세닐메틸) 2-아미노 메틸 피롤리딘으로 아미드화하는 것으로 구성되는 제1항에 따르는 화합물의 제조방법.
  3. 제1항에 따르는 화합물로 구성되는 것을 특징으로 하는 약제.
  4. 약리학적으로 허용가능한 부형제와 연합된 제1항에 따르는 화합물을 포함하는 제약학적 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019860006588A 1985-08-12 1986-08-11 신규한 벤조디옥세판의 제조방법 KR920006238B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8512270 1985-08-12
FR12270 1985-08-12
FR8512270A FR2586018B1 (fr) 1985-08-12 1985-08-12 Nouveau benzodioxepanne, son procede de synthese et ses applications en therapeutique

Publications (2)

Publication Number Publication Date
KR870002131A true KR870002131A (ko) 1987-03-30
KR920006238B1 KR920006238B1 (ko) 1992-08-01

Family

ID=9322162

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860006588A KR920006238B1 (ko) 1985-08-12 1986-08-11 신규한 벤조디옥세판의 제조방법

Country Status (41)

Country Link
US (1) US4762852A (ko)
EP (1) EP0216658B1 (ko)
JP (1) JPS63119482A (ko)
KR (1) KR920006238B1 (ko)
CN (1) CN86106163A (ko)
AR (1) AR242383A1 (ko)
AT (1) ATE49964T1 (ko)
AU (1) AU583645B2 (ko)
BE (1) BE905257A (ko)
BG (1) BG45855A3 (ko)
CA (1) CA1266670A (ko)
CH (1) CH667656A5 (ko)
CS (1) CS255879B2 (ko)
DD (1) DD251978A5 (ko)
DE (2) DE3668619D1 (ko)
DK (1) DK162995C (ko)
EG (1) EG18107A (ko)
ES (1) ES2000960A6 (ko)
FI (1) FI84603C (ko)
FR (1) FR2586018B1 (ko)
GB (1) GB2179040B (ko)
GR (1) GR862100B (ko)
HU (1) HU196392B (ko)
IL (1) IL79436A (ko)
IN (1) IN163319B (ko)
IS (1) IS1444B6 (ko)
IT (1) IT1214711B (ko)
LU (1) LU86542A1 (ko)
MA (1) MA20753A1 (ko)
NO (1) NO166447C (ko)
NZ (1) NZ217101A (ko)
OA (1) OA08382A (ko)
PH (1) PH21419A (ko)
PL (1) PL146385B1 (ko)
PT (1) PT83055B (ko)
SU (1) SU1456012A3 (ko)
TN (1) TNSN86121A1 (ko)
YU (1) YU44589B (ko)
ZA (1) ZA865739B (ko)
ZM (1) ZM6386A1 (ko)
ZW (1) ZW16086A1 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA735524B (en) * 1972-09-21 1974-07-31 Hoffmann La Roche Therapeutic compositions
US4186135A (en) * 1976-08-04 1980-01-29 Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France Substituted 2,3-alkylene bis (oxy) benzamides and derivatives and method of preparation
FR2360305A1 (fr) * 1976-08-04 1978-03-03 Ile De France Nouveaux 2,3-alkylene bis (oxy)benzamides substitues, leurs derives et leurs procedes de preparation
FR2396757A2 (fr) * 1977-07-08 1979-02-02 Ile De France Nouveaux 2,3-alkylene bis (oxy) benzamides substitues, leurs derives et leurs procedes de preparation
FR2440946A2 (fr) * 1978-01-20 1980-06-06 Ile De France Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement
US4379161A (en) * 1979-06-07 1983-04-05 Michel Thominet Novel substituted heterocyclic phenoxyamines, the method of preparation thereof and the use thereof as local anaesthetics

Also Published As

Publication number Publication date
ZM6386A1 (en) 1987-02-27
FI84603C (fi) 1991-12-27
PT83055A (fr) 1986-08-01
ZW16086A1 (en) 1987-05-20
DK381986A (da) 1987-02-13
CH667656A5 (fr) 1988-10-31
GB2179040B (en) 1989-08-16
DE3627197A1 (de) 1987-03-12
DK381986D0 (da) 1986-08-11
CS255879B2 (en) 1988-03-15
GB8619550D0 (en) 1986-09-24
IL79436A0 (en) 1986-10-31
SU1456012A3 (ru) 1989-01-30
FR2586018A1 (fr) 1987-02-13
IT8648366A0 (it) 1986-08-07
YU141786A (en) 1987-10-31
FI84603B (fi) 1991-09-13
EG18107A (en) 1991-08-30
TNSN86121A1 (fr) 1990-01-01
AU583645B2 (en) 1989-05-04
DD251978A5 (de) 1987-12-02
ES2000960A6 (es) 1988-04-01
GB2179040A (en) 1987-02-25
OA08382A (fr) 1988-02-29
PT83055B (pt) 1988-07-01
DK162995C (da) 1992-06-01
ATE49964T1 (de) 1990-02-15
CN86106163A (zh) 1987-04-08
IS3123A7 (is) 1987-02-13
HUT44783A (en) 1988-04-28
PL146385B1 (en) 1989-01-31
MA20753A1 (fr) 1987-04-01
JPS63119482A (ja) 1988-05-24
NO166447C (no) 1991-07-24
ZA865739B (en) 1987-03-25
CA1266670A (fr) 1990-03-13
FI863138A0 (fi) 1986-07-31
AU6097786A (en) 1987-02-19
FR2586018B1 (fr) 1988-03-25
US4762852A (en) 1988-08-09
EP0216658A1 (fr) 1987-04-01
NO863225D0 (no) 1986-08-11
IS1444B6 (is) 1990-12-14
IL79436A (en) 1990-09-17
DK162995B (da) 1992-01-06
HU196392B (en) 1988-11-28
YU44589B (en) 1990-10-31
CS591486A2 (en) 1987-07-16
FI863138A (fi) 1987-02-13
IT1214711B (it) 1990-01-18
DE3668619D1 (de) 1990-03-08
GR862100B (en) 1986-12-30
EP0216658B1 (fr) 1990-01-31
KR920006238B1 (ko) 1992-08-01
BG45855A3 (en) 1989-08-15
IN163319B (ko) 1988-09-03
PL260978A1 (en) 1987-03-09
BE905257A (fr) 1987-02-11
LU86542A1 (fr) 1986-12-02
AR242383A1 (es) 1993-03-31
NZ217101A (en) 1989-08-29
NO863225L (no) 1987-02-13
NO166447B (no) 1991-04-15
PH21419A (en) 1987-10-15

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