US5744500A
(en)
*
|
1990-01-03 |
1998-04-28 |
Teva Pharmaceutical Industries, Ltd. |
Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof
|
IL92952A
(en)
*
|
1990-01-03 |
1994-06-24 |
Teva Pharma |
R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them
|
IL99759A
(en)
*
|
1991-10-16 |
1997-06-10 |
Teva Pharma |
Mono-fluorinated derivatives of n-propargyl-1-aminoindan, their preparation and pharmaceutical compositions containing them
|
IL111240A
(en)
*
|
1993-10-18 |
2001-10-31 |
Teva Pharma |
Salts of r(+) - enantiomers of n- propargyl-1-aminoindan and pharmaceutical compositions comprising them
|
US5914349A
(en)
*
|
1994-01-10 |
1999-06-22 |
Teva Pharmaceutical Industries, Ltd. |
Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
|
AU1867095A
(en)
*
|
1994-01-10 |
1995-08-01 |
Technion Research & Development Foundation Ltd. |
1-aminoindan derivatives and compositions thereof
|
US5726969A
(en)
*
|
1994-12-28 |
1998-03-10 |
Matsushita Electric Industrial Co., Ltd. |
Optical recording medium having dual information surfaces
|
ZA96211B
(en)
*
|
1995-01-12 |
1996-07-26 |
Teva Pharma |
Compositions containing and methods of using 1- aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
|
TR199700878T1
(xx)
*
|
1995-03-02 |
1998-01-21 |
R.P. Scherer Limited |
Monamin oksidaz B inhibit�rleri i�eren farmakotik kompozisyonlar.
|
US5679715A
(en)
*
|
1995-06-07 |
1997-10-21 |
Harris; Richard Y. |
Method for treating multiple sclerosis
|
US5646188A
(en)
*
|
1995-07-05 |
1997-07-08 |
Teva Pharmaceutical Industries, Ltd. |
Polyamine derivatives of 1-aminoindan
|
IL115357A
(en)
*
|
1995-09-20 |
2000-01-31 |
Teva Pharma |
Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols
|
AU771490B2
(en)
*
|
1995-09-20 |
2004-03-25 |
Teva Pharmaceutical Industries Ltd. |
Stable compositions containing N-propargyl-1-aminoidan
|
IL118836A
(en)
|
1996-07-11 |
2001-01-11 |
Teva Pharma |
Pharmaceutical compositions comprising s-(-)-n-propargyl-1-aminoindan
|
US6043283A
(en)
*
|
1996-09-20 |
2000-03-28 |
Baylor College Of Medicine |
Tyramine compounds and their neuronal effects
|
US6191166B1
(en)
|
1997-11-21 |
2001-02-20 |
Elan Pharmaceuticals, Inc. |
Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis
|
US6211235B1
(en)
|
1996-11-22 |
2001-04-03 |
Elan Pharmaceuticals, Inc. |
Compounds for inhibiting β-amyloid peptide release and/or its synthesis
|
EP0966435B1
(de)
*
|
1996-12-18 |
2005-04-06 |
Teva Pharmaceutical Industries, Ltd. |
Aminoindanderivate
|
US6683075B1
(en)
|
1996-12-23 |
2004-01-27 |
Athena Neurosciences, Inc. |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use
|
US6635632B1
(en)
|
1996-12-23 |
2003-10-21 |
Athena Neurosciences, Inc. |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
|
US8048875B1
(en)
*
|
1997-02-24 |
2011-11-01 |
S.L.A. Pharma Ag |
Topical pharmaceutical composition comprising a cholinergic agent or a calcium channel blocker
|
ATE277596T1
(de)
|
1997-02-24 |
2004-10-15 |
Sla Pharma Ag |
Topische pharmazeutische zusammensetzung, enthaltend einen cholinergischen wirkstoff oder einen kalziumkanalblocker
|
GB9715082D0
(en)
*
|
1997-07-17 |
1997-09-24 |
Scherer Ltd R P |
Treatment of attention deficit hyperactivity disorder and narcolepsy
|
US5866547A
(en)
|
1998-01-20 |
1999-02-02 |
Beth Israel Deaconess Medical Center |
Methods of neuroendocrine regulation of affective disorders
|
US6509331B1
(en)
|
1998-06-22 |
2003-01-21 |
Elan Pharmaceuticals, Inc. |
Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
|
US6528505B1
(en)
|
1998-06-22 |
2003-03-04 |
Elan Pharmaceuticals, Inc. |
Cyclic amino acid compounds pharmaceutical compositions comprising same and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
|
US6774125B2
(en)
*
|
1998-06-22 |
2004-08-10 |
Elan Pharmaceuticals, Inc. |
Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
|
US6569851B1
(en)
|
1998-06-22 |
2003-05-27 |
Elan Pharmaceutials, Inc. |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
|
US6552013B1
(en)
|
1998-06-22 |
2003-04-22 |
Elan Pharmaceuticals, Inc. |
Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
|
US6232326B1
(en)
|
1998-07-14 |
2001-05-15 |
Jodi A. Nelson |
Treatment for schizophrenia and other dopamine system dysfunctions
|
JP2002529407A
(ja)
|
1998-11-10 |
2002-09-10 |
テバ ファーマシューティカル インダストリーズ リミティド |
L−dopaエチルエステル含有分散性組成物
|
US6506378B1
(en)
|
1998-12-16 |
2003-01-14 |
Arch Development Corporation |
Vesicular monoamine transporter gene therapy in Parkinson's disease
|
US6737547B1
(en)
|
1998-12-31 |
2004-05-18 |
Teva Pharmaceutical Industries, Ltd. |
Compositions containing and methods of using N-acyl-1H-aminoindenes
|
WO2001030339A1
(en)
|
1999-10-27 |
2001-05-03 |
Teva Pharmaceutical Industries, Ltd. |
Use of 1-aminoindan derivatives for treatment of mania in bipolar mood disorder
|
US6548484B1
(en)
|
2000-04-12 |
2003-04-15 |
International Medical Innovations, Inc. |
Pharmaceutical dopamine glycoconjugate compositions and methods of their preparation
|
IL141690A
(en)
*
|
2001-02-27 |
2004-06-20 |
Isp Finetech Ltd |
Process for preparation of rasagiline and its salts
|
US20040010038A1
(en)
*
|
2002-02-27 |
2004-01-15 |
Eran Blaugrund |
Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
|
AU2003282337B2
(en)
*
|
2002-11-07 |
2009-07-16 |
Technion Research And Development Foundation Ltd. |
Neuroprotective iron chelators and pharmaceutical compositions comprising them
|
US7396860B2
(en)
*
|
2002-11-15 |
2008-07-08 |
Teva Pharmaceutical Industries, Ltd. |
Use of rasagiline with or without riluzole to treat amyotrophic lateral sclerosis
|
US20040176430A1
(en)
*
|
2002-11-21 |
2004-09-09 |
Jeffrey Sterling |
Propargyl-trifluoromethoxy-amino-benzothiazole derivatives
|
EP1426049B1
(de)
*
|
2002-12-02 |
2005-05-18 |
Schwarz Pharma Ag |
Verabreichung von Rotigotine zur Behandlung der Parkinson'schen Krankheit durch Iontophorese
|
US20050192265A1
(en)
*
|
2003-03-20 |
2005-09-01 |
Thompson Richard C. |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
|
CA2547053C
(en)
|
2003-11-25 |
2014-05-27 |
Technion Research & Development Foundation Ltd. |
Compositions and methods for treatment of cardiovascular disorders and diseases
|
US8097608B2
(en)
*
|
2003-11-25 |
2012-01-17 |
Technion Research And Development Foundation Ltd. |
Methods for treatment of cardiovascular disorders and diseases
|
JP2005232148A
(ja)
*
|
2004-02-03 |
2005-09-02 |
Technion Research & Development Foundation Ltd |
神経保護剤としてプロパルギルアミンの使用
|
US20050197365A1
(en)
*
|
2004-02-27 |
2005-09-08 |
Jeffrey Sterling |
Diamino thiazoloindan derivatives and their use
|
AU2005269416B2
(en)
*
|
2004-07-26 |
2011-07-28 |
Teva Pharmaceutical Industries, Ltd. |
Pharmaceutical dosage forms including rasagiline
|
US20060025446A1
(en)
*
|
2004-07-27 |
2006-02-02 |
Jeffrey Sterling |
Propargyl nitroxides and indanyl nitroxides and their use for the treatment of neurologic diseases and disorders
|
WO2006014968A2
(en)
*
|
2004-07-27 |
2006-02-09 |
Teva Pharmaceutical Industries, Ltd. |
Propargyl nitroxydes and indanyl nitroxides and their use for the treatment of neurologic diseases and disorders
|
RS52867B
(en)
*
|
2005-02-17 |
2013-12-31 |
Teva Pharmaceutical Industries Ltd. |
GLATIRAMER ACETATOM AND RAZAGILIN COMBINED THERAPY FOR MULTIPLE SCLEROSIS
|
US20100167983A1
(en)
*
|
2007-10-22 |
2010-07-01 |
Teva Pharmaceutical Industries, Ltd. |
Combination therapy with glatiramer acetate and rasagiline for the treatment of multiple sclerosis
|
CA2600008A1
(en)
*
|
2005-02-22 |
2006-11-16 |
Teva Pharmaceutical Industries Ltd. |
Improved process for the synthesis of enantiomeric indanylamine derivatives
|
AU2006216696B2
(en)
|
2005-02-23 |
2011-08-18 |
Teva Pharmaceutical Industries, Ltd. |
Rasagiline formulations of improved content uniformity
|
EP1848417A1
(de)
*
|
2005-02-24 |
2007-10-31 |
Teva Pharmaceutical Industries Ltd |
Formulierungen von ladostigiltartrat
|
JP5253155B2
(ja)
*
|
2005-06-02 |
2013-07-31 |
ジェンリン ディスカバリー |
肥満治療に有用なmao−b阻害剤
|
US8263655B2
(en)
*
|
2005-10-06 |
2012-09-11 |
Technion Research And Development Foundation Ltd |
Methods for treatment of renal failure
|
CN101622225B
(zh)
*
|
2005-11-17 |
2015-04-15 |
泰华制药工业有限公司 |
炔丙基氨基茚分离方法
|
US7572834B1
(en)
|
2005-12-06 |
2009-08-11 |
Teva Pharmaceutical Industries, Ltd. |
Rasagiline formulations and processes for their preparation
|
US20070135518A1
(en)
*
|
2005-12-09 |
2007-06-14 |
Marta Weinstock-Rosin |
Use of low-dose ladostigil for neuroprotection
|
AU2006326642B2
(en)
|
2005-12-09 |
2012-05-03 |
Technion Research And Development Foundation Ltd. |
Use of low-dose ladostigil for neuroprotection
|
CN1990455B
(zh)
*
|
2005-12-29 |
2011-06-08 |
北京德众万全医药科技有限公司 |
一种简单、新颖的茚衍生物的制备方法
|
JP5701485B2
(ja)
|
2006-02-21 |
2015-04-15 |
テバ ファーマシューティカル インダストリーズ リミティド |
多系統萎縮症の治療のためのラサギリンの使用
|
TW200744576A
(en)
|
2006-02-24 |
2007-12-16 |
Teva Pharma |
Propargylated aminoindans, processes for preparation, and uses thereof
|
WO2007126898A2
(en)
*
|
2006-03-31 |
2007-11-08 |
Teva Pharmaceutical Industries, Ltd. |
Use of ladostigil for the treatment of schizophrenia
|
MX2008012781A
(es)
|
2006-04-03 |
2008-10-14 |
Teva Pharma |
Uso de rasagilina para el tratamiento de sindrome de piernas inquietas.
|
EP1892233A1
(de)
*
|
2006-08-18 |
2008-02-27 |
Ratiopharm GmbH |
Neue Salze des Wirkstoffs Rasagilin
|
CA2672452C
(en)
*
|
2006-12-14 |
2012-07-03 |
Teva Pharmaceutical Industries Ltd. |
Tannate salt of rasagiline
|
EA016820B1
(ru)
*
|
2006-12-14 |
2012-07-30 |
Тева Фармасьютикал Индастриз, Лтд. |
Кристаллическое твердое основание разагилина
|
EP1987816A1
(de)
*
|
2007-04-30 |
2008-11-05 |
Ratiopharm GmbH |
Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff
|
US20090062400A1
(en)
*
|
2007-09-05 |
2009-03-05 |
Laurence Oron |
Method of treating glaucoma using rasagiline
|
US8188149B2
(en)
*
|
2007-09-17 |
2012-05-29 |
Teva Pharmaceutical Industries, Ltd. |
Use of R(+)-N-propargy1-1-aminoindan to treat or prevent hearing loss
|
EP2231582B1
(de)
|
2007-12-24 |
2011-06-22 |
Cipla Limited |
Verfahren zur synthese von propargylatierten aminoindanderivativen
|
KR20100107028A
(ko)
*
|
2008-01-11 |
2010-10-04 |
테바 파마슈티컬 인더스트리즈 리미티드 |
라사길린 제형, 그들의 제법 및 용도
|
US20090247537A1
(en)
*
|
2008-03-25 |
2009-10-01 |
William Dale Overfield |
Methods for preventing or treating bruxism using dopaminergic agents
|
EP2271612B1
(de)
*
|
2008-03-31 |
2016-08-10 |
Actavis Group PTC EHF |
Rasagilinmesylatpartikel und verfahren zu deren herstellung
|
WO2009141737A2
(en)
*
|
2008-05-23 |
2009-11-26 |
Medichem, S.A. |
A new method for obtaining an aminoindan mesylate derivative
|
US20110184071A1
(en)
*
|
2008-06-02 |
2011-07-28 |
Vinayak Gore |
process for the preparation of amines
|
EP2285769B1
(de)
|
2008-06-02 |
2014-08-13 |
Generics [UK] Limited |
Verfahren zur herstellung von enantiomerenreinen aminen
|
WO2009151594A1
(en)
*
|
2008-06-10 |
2009-12-17 |
Teva Pharmaceutical Industries, Ltd. |
Rasagiline soft gelatin capsules
|
BRPI0909894A2
(pt)
*
|
2008-06-13 |
2015-07-28 |
Teva Pharma |
"método de redução da velocidade de progressão de mal de parkinson em um paciente com mal de parkinson em estágio inicial, método de redução da velocidade de progressão de mal de parkinson, método de atraso da necessidade de terapia antiparkinsoniana sintomática em um paciente de mal de parkinson em estágio inicial, método de redução do risco de um paciente com mal de parkinson que necessita de terapia antiparkinsoniana, método de redução do declínio funcional de um paciente com mal de parkinson em estágio inicial, método de redução do declínio funcional em um paciente com mal de parkinson, método de tratamento de um paciente que exibe sinais iniciais de mal de parkinson, método de redução da fadiga em um paciente com mal de parkinson em estágio inicial, método de redução da velocidade de progressão clínica e tratamento de sintomas de mal de parkinson em um paciente com mal de parkinson, rasagilina ou um sal farmaceuticamente aceitável de rasagilina, composição farmacêutica.
|
CN102065853A
(zh)
*
|
2008-06-19 |
2011-05-18 |
泰华制药工业有限公司 |
制备和干燥固体雷沙吉兰碱的方法
|
AU2009260733B2
(en)
*
|
2008-06-19 |
2015-01-29 |
Teva Pharmaceutical Industries, Ltd. |
Process for purifying rasagiline base
|
WO2011012140A2
(en)
|
2008-07-11 |
2011-02-03 |
Synthon Bv |
Polymorphs of rasagiline hydrochloride
|
IT1392914B1
(it)
*
|
2009-01-22 |
2012-04-02 |
Dipharma Francis Srl |
Procedimento per la preparazione di (r)-n-propargil-1-amminoindano e suoi sali
|
US20100029987A1
(en)
*
|
2008-07-29 |
2010-02-04 |
Dipharma Francis S.R.I. |
Crystalline Form of Rasagiline and Process for the Preparation Thereof
|
EP2181980A1
(de)
|
2008-10-28 |
2010-05-05 |
Chemo Ibérica, S.A. |
Verfahren zur Herstellung von (R)-1-Aminoindanen
|
EP2358658A4
(de)
|
2008-11-20 |
2012-11-14 |
Reddys Lab Ltd Dr |
Herstellung von rasagilin und salzen davon
|
DE102008064061A1
(de)
|
2008-12-19 |
2010-06-24 |
Ratiopharm Gmbh |
Feste Zusammensetzung mit dem Wirkstoff Rasagilin
|
US20100189788A1
(en)
|
2009-01-23 |
2010-07-29 |
Teva Pharmaceutical Industries, Ltd. |
Delayed release rasagiline base formulation
|
EP2218444A3
(de)
|
2009-01-23 |
2010-08-25 |
Teva Pharmaceutical Industries, Ltd. |
Rasagilinformulierung mit verzögerter Freisetzung
|
EP2403485A2
(de)
|
2009-03-05 |
2012-01-11 |
Sandoz AG |
Pharmazeutische zusammensetzung mit rasagilinmesylat
|
DK2451771T3
(da)
|
2009-07-09 |
2014-09-08 |
Ratiopharm Gmbh |
Salte af rasagilin og farmaceutiske fremstillingsmåder heraf
|
WO2011048612A2
(en)
*
|
2009-10-14 |
2011-04-28 |
Glenmark Generics Limited |
Processes for the preparation of propargylated aminoindans or a pharmaceutically acceptable salt thereof
|
EP2325159A1
(de)
*
|
2009-11-24 |
2011-05-25 |
LEK Pharmaceuticals d.d. |
Neuartige Salze von Rasagilin
|
US8741962B2
(en)
|
2009-11-26 |
2014-06-03 |
Usv Limited |
Process for preparation of Rasagiline and salts thereof
|
US20110152381A1
(en)
*
|
2009-12-22 |
2011-06-23 |
Anton Frenkel |
3-keto-n-propargyl-1-aminoindan
|
US20120269871A1
(en)
|
2009-12-30 |
2012-10-25 |
Actavis Group Ptc Ehf |
Solid state forms of rasagiline salts
|
WO2011095985A2
(en)
*
|
2010-02-02 |
2011-08-11 |
Glenmark Generics Limited |
Rasagiline salts and processes for the preparation thereof
|
ES2733133T3
(es)
*
|
2010-02-03 |
2019-11-27 |
Pharma Two B Ltd |
Formulaciones de liberación prolongada de rasagilina y sus usos
|
WO2011121607A2
(en)
|
2010-03-29 |
2011-10-06 |
Cadila Healthcare Limited |
Rasagiline and its pharmaceutically acceptable salts
|
CN102985082A
(zh)
|
2010-04-30 |
2013-03-20 |
帝国制药美国公司 |
丙炔基氨基茚满透皮组合物
|
EP2389927A1
(de)
|
2010-05-30 |
2011-11-30 |
Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi |
Pharmazeutische Formulationen von Rasagilin
|
AU2011282716A1
(en)
|
2010-07-27 |
2013-03-14 |
Teva Pharmaceutical Industries Ltd. |
Dispersions of rasagiline citrate
|
EP2603212A4
(de)
|
2010-07-27 |
2014-01-08 |
Teva Pharma |
Verwendung von rasagilin zur behandlung von riechstörungen
|
MX2013004598A
(es)
*
|
2010-10-26 |
2013-07-17 |
Teva Pharma |
Rasagilina enriquesida con deuterio.
|
WO2012096635A1
(en)
|
2011-01-13 |
2012-07-19 |
Fargem Farmasöti̇k Araştirma Geli̇şti̇rme Merkezi̇ Sanayi̇ Ve Ti̇caret A.Ş. |
A new method for the synthesis of rasagiline
|
WO2012116752A1
(en)
|
2011-03-03 |
2012-09-07 |
Synthon Bv |
Process of resolution of 1-aminoindan
|
CN103476404B
(zh)
|
2011-03-24 |
2017-09-29 |
帝国制药美国公司 |
包含活性剂层和活性剂转化层的透皮组合物
|
EP2705021A2
(de)
|
2011-05-04 |
2014-03-12 |
Cadila Healthcare Limited |
Rasagilin und pharmazeutisch zulässige salze davon
|
EA201490760A1
(ru)
|
2011-10-10 |
2014-09-30 |
Тева Фармасьютикал Индастриз Лтд. |
R(+)-n-метилпропаргиламиноиндан
|
JP2014534196A
(ja)
|
2011-10-10 |
2014-12-18 |
テバ ファーマシューティカル インダストリーズ リミティド |
R(+)−n−ホルミル−プロパルギル−アミノインダン
|
US9913812B2
(en)
|
2011-11-09 |
2018-03-13 |
Teikoku Pharma Usa, Inc. |
Methods for the treatment of skin neoplasms
|
EP2610239A1
(de)
|
2012-01-02 |
2013-07-03 |
Dr. Reddy's Laboratories Ltd. |
Herstellung von Rasagilin-Hemitartrat
|
DE102012000786A1
(de)
|
2012-01-18 |
2013-07-18 |
Stada Arzneimittel Ag |
Verfahren zur Herstellung einer festen pharmazeutischen Zusammensetzung, enthaltend den Wirkstoff Rasagilin
|
ES2584059T3
(es)
|
2012-03-21 |
2016-09-23 |
Synthon Bv |
Composiciones farmacéuticas estabilizadas que comprenden sales de rasagilina
|
WO2013175493A1
(en)
|
2012-04-09 |
2013-11-28 |
Cadila Healthcare Limited |
Stable oral pharmaceutical compositions
|
WO2014028868A1
(en)
|
2012-08-17 |
2014-02-20 |
Teva Pharmaceutical Industries Ltd. |
Parenteral formulation of rasagiline
|
US10918607B2
(en)
|
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|
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(es)
|
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|
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|
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(zh)
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|
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