KR870000803B1 - 도부타민 염의 제조방법 - Google Patents
도부타민 염의 제조방법 Download PDFInfo
- Publication number
- KR870000803B1 KR870000803B1 KR1019850009534A KR850009534A KR870000803B1 KR 870000803 B1 KR870000803 B1 KR 870000803B1 KR 1019850009534 A KR1019850009534 A KR 1019850009534A KR 850009534 A KR850009534 A KR 850009534A KR 870000803 B1 KR870000803 B1 KR 870000803B1
- Authority
- KR
- South Korea
- Prior art keywords
- dobutamine
- acid
- salt
- solution
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/06—Glycolic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/10—Polyhydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/10—Polyhydroxy carboxylic acids
- C07C59/105—Polyhydroxy carboxylic acids having five or more carbon atoms, e.g. aldonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/255—Tartaric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/285—Polyhydroxy dicarboxylic acids having five or more carbon atoms, e.g. saccharic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Detergent Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Seasonings (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68440484A | 1984-12-20 | 1984-12-20 | |
| US684404 | 1984-12-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR860004834A KR860004834A (ko) | 1986-07-14 |
| KR870000803B1 true KR870000803B1 (ko) | 1987-04-20 |
Family
ID=24747892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019850009534A Expired KR870000803B1 (ko) | 1984-12-20 | 1985-12-18 | 도부타민 염의 제조방법 |
Country Status (24)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA881076B (en) * | 1987-02-24 | 1989-10-25 | Lilly Co Eli | Dobutamine salts |
| FR2740337B1 (fr) * | 1995-10-27 | 1997-11-21 | Rhone Poulenc Rorer Sa | Compositions pharmaceutiques stabilisees contenant un derive ayant une activite adrenergique |
| FR2740338B1 (fr) * | 1995-12-01 | 1997-12-05 | Rhone Poulenc Rorer Sa | Compositions pharmaceutiques stabilisees contenant de la dobutamine |
| FR2809619B1 (fr) * | 2000-06-06 | 2004-09-24 | Pharmatop | Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention |
| CN105906515B (zh) * | 2015-12-10 | 2018-03-13 | 菏泽市方明制药有限公司 | 一种盐酸多巴酚丁胺脱色工艺 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3987200A (en) * | 1972-04-12 | 1976-10-19 | Eli Lilly And Company | Method for increasing cardiac contractility |
| FR2333499A1 (fr) * | 1975-12-01 | 1977-07-01 | Roussel Uclaf | Nouveau derive de la phenethylamine et ses sels, procede de preparation et application a titre de medicament |
-
1985
- 1985-12-16 RO RO121165A patent/RO93391B/ro unknown
- 1985-12-17 PL PL1985256848A patent/PL148296B1/pl unknown
- 1985-12-17 ZA ZA859629A patent/ZA859629B/xx unknown
- 1985-12-17 FI FI855018A patent/FI855018A7/fi not_active Application Discontinuation
- 1985-12-17 GR GR853027A patent/GR853027B/el unknown
- 1985-12-17 NZ NZ214583A patent/NZ214583A/xx unknown
- 1985-12-18 CA CA000497954A patent/CA1254909A/en not_active Expired
- 1985-12-18 EG EG809/85A patent/EG17889A/xx active
- 1985-12-18 DE DE8585309216T patent/DE3580575D1/de not_active Expired - Lifetime
- 1985-12-18 DE DE198585309216T patent/DE187019T1/de active Pending
- 1985-12-18 CS CS859449A patent/CS253734B2/cs unknown
- 1985-12-18 PT PT81705A patent/PT81705B/pt not_active IP Right Cessation
- 1985-12-18 DD DD85284649A patent/DD241071A5/de not_active IP Right Cessation
- 1985-12-18 AT AT85309216T patent/ATE58370T1/de not_active IP Right Cessation
- 1985-12-18 DK DK589385A patent/DK589385A/da not_active Application Discontinuation
- 1985-12-18 KR KR1019850009534A patent/KR870000803B1/ko not_active Expired
- 1985-12-18 EP EP85309216A patent/EP0187019B1/en not_active Expired - Lifetime
- 1985-12-18 SU SU853995134A patent/SU1480761A3/ru active
- 1985-12-18 PH PH33213A patent/PH22547A/en unknown
- 1985-12-18 AU AU51415/85A patent/AU589929B2/en not_active Ceased
- 1985-12-19 JP JP60287570A patent/JPS61155355A/ja active Granted
- 1985-12-19 ES ES550151A patent/ES8705841A1/es not_active Expired
- 1985-12-19 HU HU854878A patent/HU194805B/hu not_active IP Right Cessation
- 1985-12-19 CN CN85109229A patent/CN1009922B/zh not_active Expired
-
1987
- 1987-02-26 ES ES557426A patent/ES8802570A1/es not_active Expired
- 1987-10-08 MY MYPI87002873A patent/MY104814A/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| PA0109 | Patent application |
St.27 status event code: A-0-1-A10-A12-nap-PA0109 |
|
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| G160 | Decision to publish patent application | ||
| PG1605 | Publication of application before grant of patent |
St.27 status event code: A-2-2-Q10-Q13-nap-PG1605 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
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| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
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| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U11-oth-PR1002 Fee payment year number: 1 |
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| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 4 |
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| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 5 |
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| FPAY | Annual fee payment |
Payment date: 19920427 Year of fee payment: 6 |
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| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 6 |
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| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 19930421 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
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| PC1903 | Unpaid annual fee |
St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 19930421 |
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| P22-X000 | Classification modified |
St.27 status event code: A-4-4-P10-P22-nap-X000 |
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| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |