KR860001394B1 - 황산 크실란의 제조 방법 - Google Patents

황산 크실란의 제조 방법 Download PDF

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Publication number
KR860001394B1
KR860001394B1 KR1019840001491A KR840001491A KR860001394B1 KR 860001394 B1 KR860001394 B1 KR 860001394B1 KR 1019840001491 A KR1019840001491 A KR 1019840001491A KR 840001491 A KR840001491 A KR 840001491A KR 860001394 B1 KR860001394 B1 KR 860001394B1
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KR
South Korea
Prior art keywords
solution
xylan
acid
distilled water
sulfation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019840001491A
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English (en)
Korean (ko)
Other versions
KR840008376A (ko
Inventor
바욜 알랭
란슨 쟈끄린느
마프랑드 쨩-삐에르
뻬레이로 짱-마리
발레 에리끄
Original Assignee
사노피 소시에떼아노님
미셸드 아스
아니크 에스. 피. 에이.
카르로 치오니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 사노피 소시에떼아노님, 미셸드 아스, 아니크 에스. 피. 에이., 카르로 치오니 filed Critical 사노피 소시에떼아노님
Publication of KR840008376A publication Critical patent/KR840008376A/ko
Application granted granted Critical
Publication of KR860001394B1 publication Critical patent/KR860001394B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/14—Hemicellulose; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0057—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Xylans, i.e. xylosaccharide, e.g. arabinoxylan, arabinofuronan, pentosans; (beta-1,3)(beta-1,4)-D-Xylans, e.g. rhodymenans; Hemicellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
KR1019840001491A 1983-03-24 1984-03-21 황산 크실란의 제조 방법 Expired KR860001394B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8305170 1983-03-24
FR8305170A FR2543145B1 (fr) 1983-03-24 1983-03-24 Nouveaux sulfates de xylanes, leur procede de preparation et leur activite anti-thrombotique et hypolipemiante

Publications (2)

Publication Number Publication Date
KR840008376A KR840008376A (ko) 1984-12-14
KR860001394B1 true KR860001394B1 (ko) 1986-09-22

Family

ID=9287351

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840001491A Expired KR860001394B1 (ko) 1983-03-24 1984-03-21 황산 크실란의 제조 방법

Country Status (16)

Country Link
US (1) US4699900A (enExample)
EP (1) EP0125152B1 (enExample)
JP (1) JPS6063203A (enExample)
KR (1) KR860001394B1 (enExample)
AT (1) ATE24520T1 (enExample)
AU (1) AU561588B2 (enExample)
CA (1) CA1221090A (enExample)
DE (1) DE3461808D1 (enExample)
DK (1) DK55784A (enExample)
ES (1) ES8500962A1 (enExample)
FR (1) FR2543145B1 (enExample)
GR (1) GR79831B (enExample)
IL (1) IL70846A0 (enExample)
NZ (1) NZ207622A (enExample)
PT (1) PT78179B (enExample)
ZA (1) ZA842176B (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2543145B1 (fr) * 1983-03-24 1986-10-17 Sanofi Sa Nouveaux sulfates de xylanes, leur procede de preparation et leur activite anti-thrombotique et hypolipemiante
FR2572731B1 (fr) * 1984-11-07 1987-03-06 Sanofi Sa Nouveaux sulfates de xylanes de bas poids moleculaires, leur procede de preparation et leur activite antithrombotique et hypolipemiante par voie orale
FR2574663B1 (fr) * 1984-12-17 1987-01-16 Sanofi Sa Nouvelle composition therapeutique a activite antithrombotique et hypolipemiante a base de xylanes et d'un acide organique
US4966890A (en) * 1986-04-04 1990-10-30 Angiogenics, Ltd. Method and composition for arresting angiogenesis and capillary, cell or membrane leakage
US4820693A (en) * 1986-05-22 1989-04-11 Angiogenics, Ltd. Method and composition for arresting angiogenesis and capillary, cell or membrane leakage
US5484777A (en) * 1989-04-20 1996-01-16 Lange, Iii; Louis G. Pancreatic cholesterol esterase inhibitor
US5017565A (en) * 1989-04-20 1991-05-21 Lange Iii Louis G Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase
US5063210A (en) * 1989-04-20 1991-11-05 Lange Iii Louis G Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption
DE3917982A1 (de) * 1989-06-02 1990-12-06 Behringwerke Ag Verwendung von xylanpolyhydrogensulfaten zur therapie von zellproliferations-bedingten erkrankungen
FR2655267B1 (fr) * 1989-12-04 1992-04-03 Roussel Uclaf Nouveau derive sulfate du galactanne extrait de klebsiella, procede de preparation, application a titre de medicaments et compositions pharmaceutiques le renfermant.
US5141928B1 (en) * 1989-12-20 1995-11-14 Brujo Inc Ophthalmic medication
US5378829A (en) * 1990-04-23 1995-01-03 Akzo N.V. Sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type
US5382570A (en) * 1990-04-23 1995-01-17 Akzo, N.V. Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
US5668274A (en) * 1991-04-23 1997-09-16 Akzo Nobel N.V. Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
IL102758A (en) * 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
US5639469A (en) * 1994-06-15 1997-06-17 Minnesota Mining And Manufacturing Company Transmucosal delivery system
US6255295B1 (en) 1996-12-23 2001-07-03 Nutramax Laboratories, Inc. Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue
US6451771B1 (en) 1999-02-12 2002-09-17 Nutramax Laboratories, Inc. Use of anabolic agents anti-catabolic agents and antioxidant agents for protection treatment and repair of connective tissues in humans and animals
US20070141181A1 (en) * 1998-02-13 2007-06-21 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
US6797289B2 (en) * 1998-02-13 2004-09-28 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
ES2251289B1 (es) * 2004-02-27 2007-07-01 Bioiberica, S.A. Nuevo uso terapeutico de un grupo de polisacaridos sulfatados.
WO2009047699A1 (en) * 2007-10-10 2009-04-16 Alembic Limited An improved process for the preparation of an amorphous form of pentosan polysulfate or salts thereof
AU2008100730B4 (en) * 2008-07-04 2008-10-02 Parnell Technologies Pty Ltd Sulfated polysaccharide compound for clinical use and the preparation thereof
WO2011088418A2 (en) * 2010-01-15 2011-07-21 Mount Sinai School Of Medicine Inhibition of tnf-alpha induced activation of nfkb by pentosan polysulfate
WO2012101544A1 (en) * 2011-01-29 2012-08-02 Alembic Pharmaceuticals Limited An improved process for the preparation of pentosan polysulfate or salts thereof
WO2012114349A1 (en) * 2011-02-23 2012-08-30 Cadila Healthcare Limited An improved process for the preparation of pentosan polysulfate sodium
SG11202001824RA (en) 2016-08-31 2020-04-29 Oji Holdings Corp Production method for acidic xylooligosaccharide, and acidic xylooligosaccharide
JP6225321B1 (ja) 2016-08-31 2017-11-08 王子ホールディングス株式会社 ポリ硫酸ペントサンの製造方法
JP6281659B1 (ja) 2017-02-28 2018-02-21 王子ホールディングス株式会社 ポリ硫酸ペントサン、医薬組成物及び抗凝固剤
WO2018221547A1 (ja) 2017-05-31 2018-12-06 王子ホールディングス株式会社 保湿外用剤
AU2018333249B2 (en) * 2017-09-12 2023-03-02 Oji Holdings Corporation Pentosan polysulfate and method for producing pentosan polysulfate
HUE062342T2 (hu) * 2017-12-20 2023-10-28 Oji Holdings Corp Pentozán-poliszulfát, valamint pentozán-poliszulfátot tartalmazó gyógyszerek

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH290145A (de) * 1944-06-13 1953-04-15 Kaulla Kurt Nikolai Dr Med Von Verfahren zur Herstellung von Schwefelsäureestern des Xylans.
FR1050576A (fr) * 1951-02-06 1954-01-08 Wander Ag Dr A Procédé pour la préparation de sels alcalins de l'ester sulfurique du xylane
US3290263A (en) * 1962-08-02 1966-12-06 Colonial Sugar Refining Co Process of reacting sugars with reagents wherein the sugar is dissolved in monohydric alcohols containing grouping
ES343957A1 (es) * 1967-08-09 1968-10-01 Rocador Sa Procedimiento de obtencion de polisacaridos sulfatados an- tilipemicos activos por via oral.
US4098995A (en) * 1976-07-12 1978-07-04 American Cyanamid Company Polygalactosido-sucrose poly(h-)sulfate salts
US4301153A (en) * 1977-03-21 1981-11-17 Riker Laboratories, Inc. Heparin preparation
US4122250A (en) * 1977-08-22 1978-10-24 Gottfried Schmer Separation of high-activity heparin by affinity chromatography
US4221907A (en) * 1979-07-09 1980-09-09 American Cyanamid Company Substituted O-α-D and O-β-D-multi-galactopyranosyl and glucopyranosyl 1→4 and 1→6 galactopyranosyl 1→6 α-D-glucopyranoses
DE2945595A1 (de) * 1979-11-12 1981-05-21 Sandoz-Patent-GmbH, 7850 Lörrach Verfahren zur herstellung von niedermolekularem heparin bzw. seinen salzen
US4281108A (en) * 1980-01-28 1981-07-28 Hepar Industries, Inc. Process for obtaining low molecular weight heparins endowed with elevated pharmacological properties, and product so obtained
FR2543145B1 (fr) * 1983-03-24 1986-10-17 Sanofi Sa Nouveaux sulfates de xylanes, leur procede de preparation et leur activite anti-thrombotique et hypolipemiante

Also Published As

Publication number Publication date
ES530266A0 (es) 1984-11-01
DK55784D0 (da) 1984-02-08
NZ207622A (en) 1986-08-08
JPS6063203A (ja) 1985-04-11
EP0125152B1 (fr) 1986-12-30
KR840008376A (ko) 1984-12-14
ATE24520T1 (de) 1987-01-15
FR2543145A1 (fr) 1984-09-28
DE3461808D1 (en) 1987-02-05
IL70846A0 (en) 1984-05-31
ES8500962A1 (es) 1984-11-01
DK55784A (da) 1984-09-25
PT78179A (fr) 1984-04-01
AU561588B2 (en) 1987-05-14
ZA842176B (en) 1984-10-31
CA1221090A (fr) 1987-04-28
AU2441284A (en) 1984-09-27
US4699900A (en) 1987-10-13
FR2543145B1 (fr) 1986-10-17
PT78179B (fr) 1986-04-24
GR79831B (enExample) 1984-10-31
EP0125152A1 (fr) 1984-11-14

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