KR850001291A - 폴리에테르 항생물질 x-14934a의 제조방법 - Google Patents

폴리에테르 항생물질 x-14934a의 제조방법 Download PDF

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KR850001291A
KR850001291A KR1019840004421A KR840004421A KR850001291A KR 850001291 A KR850001291 A KR 850001291A KR 1019840004421 A KR1019840004421 A KR 1019840004421A KR 840004421 A KR840004421 A KR 840004421A KR 850001291 A KR850001291 A KR 850001291A
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formula
compound
preparing polyether
polyether antibiotic
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KR1019840004421A
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KR910005629B1 (ko
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웨슬리 존 (외 1)
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진-작크스오게이,메인라드 쉬미드
에프호프만-라 롯슈 앤드 캄파니 아크티엔 게쩔샤프트
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Publication of KR850001291A publication Critical patent/KR850001291A/ko
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Publication of KR910005629B1 publication Critical patent/KR910005629B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/54—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being bound directly to a nitrogen atom of two or more radicals, e.g. streptomycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/445—The saccharide radical is condensed with a heterocyclic radical, e.g. everninomycin, papulacandin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/55—Streptomyces hygroscopicus

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Fodder In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

내용 없음

Description

폴리에테르 항생물질 X-14934A의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 호기성 액침 배양조건하에 질소영향물을 함유하는 탄수화물 수용액중에서 스트렙토마이세스 X-14934 균주를 배양시킨 후 상기 용액으로부터 일반식(I)의 화합물을 분리시키고, 경우에 따라 일반식(I)의 화합물의 염을 형성시킴을 특징으로 하는 일반식(I) 화합물의 제조방법.
  2. 제1항에 있어서 일반식(I) 화합물의 나트륨염을 제조하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019840004421A 1983-07-28 1984-07-25 폴리에테르 항생물질 x-14934a의 제조방법 KR910005629B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/518,233 US4510317A (en) 1983-07-28 1983-07-28 Antibiotic X-14934A
US518233 1983-07-28

Publications (2)

Publication Number Publication Date
KR850001291A true KR850001291A (ko) 1985-03-18
KR910005629B1 KR910005629B1 (ko) 1991-08-01

Family

ID=24063126

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840004421A KR910005629B1 (ko) 1983-07-28 1984-07-25 폴리에테르 항생물질 x-14934a의 제조방법

Country Status (21)

Country Link
US (1) US4510317A (ko)
EP (1) EP0133971B1 (ko)
JP (1) JPS6051198A (ko)
KR (1) KR910005629B1 (ko)
AT (1) ATE33390T1 (ko)
AU (1) AU575574B2 (ko)
CA (1) CA1253097A (ko)
DE (1) DE3470313D1 (ko)
DK (1) DK159452C (ko)
ES (1) ES534644A0 (ko)
FI (1) FI76836C (ko)
GR (1) GR82437B (ko)
HU (1) HU193017B (ko)
IE (1) IE57274B1 (ko)
IL (1) IL72517A (ko)
MC (1) MC1615A1 (ko)
NO (1) NO158881C (ko)
NZ (1) NZ209022A (ko)
PH (1) PH20120A (ko)
PT (1) PT78991B (ko)
ZA (1) ZA845601B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707493A (en) * 1983-02-15 1987-11-17 Pfizer Inc. 19-epi-dianemycin as an anticoccidial and antibacterial agent
US4591559A (en) * 1983-07-28 1986-05-27 Hoffmann-La Roche Inc. Antibiotic X-14934A and a method for its preparation
US4625041A (en) * 1984-02-17 1986-11-25 Pfizer Inc. Acidic polycyclic ether antibiotic
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
EP0209971B1 (en) * 1985-05-28 1991-03-06 Eli Lilly And Company Polyether antibiotic and process for its production
US5888788A (en) * 1994-05-18 1999-03-30 Union Nationale Des Groupements De Distillateurs D'alcool (Ungda) Use of ionophoretic polyether antibiotics for controlling bacterial growth in alcoholic fermentation
TW393413B (en) * 1996-01-19 2000-06-11 Shimano Kk Clipless bicycle pedal with large shoe-contacting area
EP2825178A4 (en) * 2012-03-16 2015-10-14 Univ Georgia GLYCOMIMETIKA FOR INHIBITING PATHOGEN HOST INTERACTIONS

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953474A (en) * 1974-11-15 1976-04-27 Eli Lilly And Company Antibiotic A204I derivatives
GB2024806B (en) * 1978-03-16 1982-05-06 Taisho Pharmaceutical Co Ltd Onomycin derivatives
JPS5592387A (en) * 1978-12-29 1980-07-12 Taisho Pharmaceut Co Ltd Antibiotic substance tm-531
US4431665A (en) * 1979-08-13 1984-02-14 Syntex (U.S.A.) Inc. Acylated laidlomycin derivatives
FR2463144A1 (fr) * 1979-08-13 1981-02-20 Syntex Inc Nouveaux diesters de laidlomycine, leur procede de production, compositions a usage veterinaire les contenant et leur utilisation pour accroitre le rendement d'assimilation des aliments chez un ruminant
US4359583A (en) * 1980-09-16 1982-11-16 Taisho Pharmaceutical Co., Ltd. Antibiotics TM-531 B and TM-531 C
US4361649A (en) * 1981-07-20 1982-11-30 Pfizer Inc. Polycyclic ether antibiotic
GB2113671A (en) * 1982-01-19 1983-08-10 Pfizer Ltd Polycyclic ether antibiotics
GT198400008A (es) * 1983-02-15 1985-07-12 19-epi-dianemicina y procedimiento para el mismo
US4552843A (en) * 1984-02-17 1985-11-12 Pfizer Inc. Process for producing an acidic polycyclic ether antibiotic by cultivation of a novel strain of Streptomyces endus subspecies aureus

Also Published As

Publication number Publication date
ES8600640A1 (es) 1985-10-16
PT78991B (en) 1986-10-23
DK366084A (da) 1985-01-29
IE57274B1 (en) 1992-07-01
NO843054L (no) 1985-01-29
HUT36178A (en) 1985-08-28
EP0133971B1 (de) 1988-04-06
GR82437B (ko) 1984-12-13
HU193017B (en) 1987-08-28
NO158881C (no) 1988-11-09
PH20120A (en) 1986-10-02
ZA845601B (en) 1985-03-27
DK159452B (da) 1990-10-15
NO158881B (no) 1988-08-01
AU575574B2 (en) 1988-08-04
IL72517A (en) 1988-03-31
DE3470313D1 (en) 1988-05-11
US4510317A (en) 1985-04-09
FI76836B (fi) 1988-08-31
AU3124684A (en) 1985-01-31
KR910005629B1 (ko) 1991-08-01
NZ209022A (en) 1987-08-31
MC1615A1 (fr) 1985-07-18
PT78991A (en) 1984-08-01
CA1253097A (en) 1989-04-25
FI843009A0 (fi) 1984-07-27
FI843009A (fi) 1985-01-29
DK159452C (da) 1991-03-18
IE841949L (en) 1985-01-28
EP0133971A1 (de) 1985-03-13
IL72517A0 (en) 1984-11-30
ATE33390T1 (de) 1988-04-15
JPS6051198A (ja) 1985-03-22
ES534644A0 (es) 1985-10-16
DK366084D0 (da) 1984-07-26
FI76836C (fi) 1988-12-12

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