KR840008367A - 악타플라닌 항생물질의 제조방법 - Google Patents
악타플라닌 항생물질의 제조방법 Download PDFInfo
- Publication number
- KR840008367A KR840008367A KR1019840002239A KR840002239A KR840008367A KR 840008367 A KR840008367 A KR 840008367A KR 1019840002239 A KR1019840002239 A KR 1019840002239A KR 840002239 A KR840002239 A KR 840002239A KR 840008367 A KR840008367 A KR 840008367A
- Authority
- KR
- South Korea
- Prior art keywords
- hydrogen
- acttaplanin
- antibiotic
- preparing
- glucosyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (1)
- 인자 A, B1, B2, B3, C1a, C3및 G로 이루어진 그룹에서 선택된 적절한 악타플라닌 인자를 80내지 100℃의 온도 및 1.5내지 2.0의 pH에서 부분적으로 가수분해시킴을 특징으로 하여 다음 일반식(I)의 화합물 및 그의 약학적으로 허용되는 염을 제조하는 방법.상기식에서, R은 L-리스토아민이고; R1은 수소, 글루코실, 또는 디사카라이드 만노실-글루코스 또는 람노실-글루코스이며; R2및 R3는 각각 수소 또는 만노스이다. (단 R1이 수소이면 R2나 R3중의 하나 또는 둘다 만노스이고; R1이 글루코실이면 R2및 R3는 둘다 수소이며; R1이 디사카라이드면 R2는 수소이다).※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US488967 | 1983-04-27 | ||
| US06/488,967 US4479897A (en) | 1983-04-27 | 1983-04-27 | Actaplanin antibiotics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR840008367A true KR840008367A (ko) | 1984-12-14 |
| KR880000133B1 KR880000133B1 (ko) | 1988-03-12 |
Family
ID=23941856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019840002239A KR880000133B1 (ko) | 1983-04-27 | 1984-04-26 | 악타플라닌 항생물질의 제조방법 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4479897A (ko) |
| EP (1) | EP0124343A1 (ko) |
| JP (1) | JPS59205392A (ko) |
| KR (1) | KR880000133B1 (ko) |
| DK (1) | DK210284A (ko) |
| GB (1) | GB2138822B (ko) |
| GR (1) | GR79574B (ko) |
| HU (1) | HU189869B (ko) |
| IL (1) | IL71625A0 (ko) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8307847D0 (en) * | 1983-03-22 | 1983-04-27 | Lepetit Spa | Antibiotics l 17054 and l 17046 |
| US4558036A (en) * | 1984-02-17 | 1985-12-10 | Eli Lilly And Company | Actaplanin antibiotics |
| US4547488A (en) * | 1984-04-16 | 1985-10-15 | Eli Lilly And Company | Antibiotic M43D, pharmaceutical compositions and method of use |
| EP0368949A1 (en) * | 1988-02-10 | 1990-05-23 | Beecham Group Plc | Novel antibiotic compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3952095A (en) * | 1972-06-02 | 1976-04-20 | Eli Lilly And Company | Novel antibiotic and a process for the production thereof |
| US3928571A (en) * | 1972-12-15 | 1975-12-23 | Lilly Co Eli | Ruminant feed utilization improvement |
| US4064233A (en) * | 1974-12-17 | 1977-12-20 | Eli Lilly And Company | Antibiotic A-4696 |
| US4115552A (en) * | 1976-04-19 | 1978-09-19 | Eli Lilly And Company | Factor A and B of antibiotic A-4696 |
| US4322406A (en) * | 1980-12-18 | 1982-03-30 | Eli Lilly And Company | Antibiotic A-4696 factors B1, B2, B3, C1a, C3 and E1 |
| IL64486A (en) * | 1980-12-18 | 1985-01-31 | Lilly Co Eli | Antibiotic a-4696 factor g,its preparation and use as feed supplement for ruminant animals |
| US4322343A (en) * | 1980-12-18 | 1982-03-30 | Eli Lilly And Company | Pseudo-aglycone of actaplanin |
-
1983
- 1983-04-27 US US06/488,967 patent/US4479897A/en not_active Expired - Fee Related
-
1984
- 1984-04-25 EP EP84302779A patent/EP0124343A1/en not_active Withdrawn
- 1984-04-25 IL IL71625A patent/IL71625A0/xx unknown
- 1984-04-25 GB GB08410585A patent/GB2138822B/en not_active Expired
- 1984-04-26 GR GR74510A patent/GR79574B/el unknown
- 1984-04-26 JP JP59086015A patent/JPS59205392A/ja active Pending
- 1984-04-26 HU HU841620A patent/HU189869B/hu unknown
- 1984-04-26 KR KR1019840002239A patent/KR880000133B1/ko active IP Right Grant
- 1984-04-26 DK DK210284A patent/DK210284A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR880000133B1 (ko) | 1988-03-12 |
| GB8410585D0 (en) | 1984-05-31 |
| JPS59205392A (ja) | 1984-11-20 |
| GB2138822B (en) | 1986-08-28 |
| GR79574B (ko) | 1984-10-30 |
| HUT34043A (en) | 1985-01-28 |
| US4479897A (en) | 1984-10-30 |
| IL71625A0 (en) | 1984-07-31 |
| DK210284D0 (da) | 1984-04-26 |
| EP0124343A1 (en) | 1984-11-07 |
| DK210284A (da) | 1984-10-28 |
| GB2138822A (en) | 1984-10-31 |
| HU189869B (en) | 1986-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| G160 | Decision to publish patent application | ||
| E701 | Decision to grant or registration of patent right | ||
| NORF | Unpaid initial registration fee |