KR850000760B1 - 인돌 유도체의 제조방법 - Google Patents

인돌 유도체의 제조방법 Download PDF

Info

Publication number
KR850000760B1
KR850000760B1 KR1019800000931A KR800000931A KR850000760B1 KR 850000760 B1 KR850000760 B1 KR 850000760B1 KR 1019800000931 A KR1019800000931 A KR 1019800000931A KR 800000931 A KR800000931 A KR 800000931A KR 850000760 B1 KR850000760 B1 KR 850000760B1
Authority
KR
South Korea
Prior art keywords
indole
imidazolylmethyl
solution
mixture
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019800000931A
Other languages
English (en)
Korean (ko)
Other versions
KR830001928A (ko
Inventor
에드워드 크로스 피터
피터 딕킨슨 로저
Original Assignee
화이자 리미티드
존 알머 마즈, 죠지 알란 스미
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 화이자 리미티드, 존 알머 마즈, 죠지 알란 스미 filed Critical 화이자 리미티드
Publication of KR830001928A publication Critical patent/KR830001928A/ko
Application granted granted Critical
Publication of KR850000760B1 publication Critical patent/KR850000760B1/ko
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019800000931A 1979-03-07 1980-03-06 인돌 유도체의 제조방법 Expired KR850000760B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB08123 1979-03-07
GB7908123 1979-03-07
GB7908123 1979-03-07

Publications (2)

Publication Number Publication Date
KR830001928A KR830001928A (ko) 1983-05-19
KR850000760B1 true KR850000760B1 (ko) 1985-05-25

Family

ID=10503707

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019800000931A Expired KR850000760B1 (ko) 1979-03-07 1980-03-06 인돌 유도체의 제조방법

Country Status (36)

Country Link
US (1) US4273782A (enExample)
JP (1) JPS55133380A (enExample)
KR (1) KR850000760B1 (enExample)
AR (1) AR227015A1 (enExample)
AT (1) AT375366B (enExample)
AU (1) AU516957B2 (enExample)
BE (1) BE882113A (enExample)
CA (1) CA1120479A (enExample)
CH (1) CH649546A5 (enExample)
CS (1) CS253702B2 (enExample)
DD (1) DD149525A5 (enExample)
DE (1) DE3008632A1 (enExample)
DK (1) DK151884C (enExample)
ES (2) ES8104278A1 (enExample)
FI (1) FI66860C (enExample)
FR (1) FR2450832A1 (enExample)
GR (1) GR67237B (enExample)
HK (1) HK89884A (enExample)
HU (1) HU184727B (enExample)
IE (1) IE49542B1 (enExample)
IL (1) IL59524A (enExample)
IT (1) IT1218420B (enExample)
KE (1) KE3467A (enExample)
LU (1) LU82224A1 (enExample)
MY (1) MY8500285A (enExample)
NL (1) NL182959C (enExample)
NO (1) NO152217C (enExample)
NZ (1) NZ193052A (enExample)
PH (1) PH15198A (enExample)
PL (1) PL128296B1 (enExample)
PT (1) PT70914A (enExample)
SE (1) SE440778B (enExample)
SG (1) SG67284G (enExample)
SU (1) SU1277894A3 (enExample)
YU (1) YU41911B (enExample)
ZA (1) ZA801328B (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4414159A (en) * 1980-09-26 1983-11-08 E. I. Du Pont De Nemours & Co. Vinyl ether monomers and polymers therefrom
US4444775A (en) * 1981-06-22 1984-04-24 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridines
KR840000529A (ko) * 1981-07-07 1984-02-25 콘스탄틴 루이스 클레멘트 인돌 유도체의 제조방법
ZA825413B (en) * 1981-08-26 1983-06-29 Pfizer Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4539410A (en) * 1982-09-30 1985-09-03 Ciba-Geigy Corporation N-Substituted-2-(1-imidazolyl)indoles
US4436746A (en) 1982-09-30 1984-03-13 Ciba-Geigy Corporation Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)indoles
AT376436B (de) * 1982-11-05 1984-11-26 Laevosan Gmbh & Co Kg Verfahren zur herstellung neuer thiophen-2carbons[urederivate und pharmazeutisch vertraeglicher saeure- oder basenadditionssalze davon
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles
DE3786030T2 (de) 1986-03-27 1993-12-02 Merck Frosst Canada Inc Tetrahydrocarbazole Ester.
JPH0832679B2 (ja) * 1986-09-05 1996-03-29 理化学研究所 Ｎ―フタルイシド誘導体及びその製造法
GR871809B (en) * 1986-11-28 1988-03-07 Glaxo Group Ltd Process for the preparation of tricyclic ketones
CA2030557A1 (en) * 1989-03-31 1990-10-01 Hiroshi Matsui Imidazole derivatives, methods for their production and pharmaceutical use thereof
EP0636623B1 (en) * 1990-06-07 2001-08-16 AstraZeneca AB Indole derivatives as 5-HT1- like agonists
DE4023215A1 (de) * 1990-07-21 1992-01-23 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
KR930702334A (ko) * 1990-09-13 1993-09-08 데이비드 로버트 5 하이드록시트립타민 수용체 길항제로서의 인돌우레아
US5162337A (en) * 1990-10-05 1992-11-10 Merck & Co., Inc. Animal growth promotion
US5120749A (en) * 1991-02-20 1992-06-09 Abbott Laboratories Platelet activating antagonists
DK0618913T3 (da) * 1991-12-18 1996-10-14 Schering Corp Imidazolyl eller imidazoylalkyl substitueret med en 4- eller 5-leddet nitrogenholdig heterocyclisk ring
WO1993020065A1 (fr) * 1992-03-27 1993-10-14 Kyoto Pharmaceutical Industries, Ltd. Nouveau derive d'imidazole, son utilisation pharmaceutique, et intermediaire associe
US5538973A (en) * 1992-03-27 1996-07-23 Kyoto Pharmaceutical Industries, Ltd. Imidazole derivative, pharmaceutical use thereof, and intermediate therefor
JPH0632913U (ja) * 1992-09-18 1994-04-28 三洋電機株式会社 床暖房用パネル
CA2383983C (en) * 1998-03-31 2009-09-29 The Institutes For Pharmaceutical Discovery, Llc Substituted indolealkanoic acids
JP4286782B2 (ja) * 2002-09-12 2009-07-01 エフ．ホフマン−ラ ロシュ アーゲー 糖尿病の治療に有用な、ｐｐａｒアゴニストとしてのｎ−置換−１ｈ−インドール−５−プロピオン酸化合物
RU2315767C2 (ru) * 2002-11-25 2008-01-27 Ф.Хоффманн-Ля Рош Аг Индолилпроизводные, способ их получения, фармацевтическая композиция, способ лечения и/или профилактики заболеваний
ATE331708T1 (de) * 2002-12-10 2006-07-15 Wyeth Corp Substituierte 3-alkyl- und 3-arylalkyl-1h-indol-1-yl-essigsäure-derivate als plasminogen aktivator inhibitor-1 (pai-1) inhibitoren
GB0324763D0 (en) * 2003-10-23 2003-11-26 Oxagen Ltd Use of compounds in therapy
ES2329489T3 (es) * 2004-05-03 2009-11-26 F. Hoffmann-La Roche Ag Derivados de indolilo como moduladores del receptor x del higado.
CN101142184A (zh) * 2004-10-12 2008-03-12 解码遗传Ehf公司 用于阻塞性动脉疾病的磺酰胺迫位取代的双环化合物
AU2006283104A1 (en) * 2005-08-25 2007-03-01 Pharmacopeia, Inc. Imidazole derivatives as functionally selective alpha2C adrenoreceptor agonists
US8399666B2 (en) * 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) * 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) * 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
KR20090018934A (ko) * 2006-05-16 2009-02-24 디코드 제네틱스 이에이치에프 7-(아크릴로일)인돌의 제조방법
AU2007279079A1 (en) 2006-07-22 2008-01-31 Oxagen Limited Compounds having CRTH2 antagonist activity
TW200920369A (en) * 2007-10-26 2009-05-16 Amira Pharmaceuticals Inc 5-lipoxygenase activating protein (flap) inhibitor
US20110015158A1 (en) 2007-12-11 2011-01-20 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties
US7750027B2 (en) * 2008-01-18 2010-07-06 Oxagen Limited Compounds having CRTH2 antagonist activity
HRP20140045T1 (hr) 2008-01-18 2014-02-14 Atopix Therapeutics Limited Spojevi koji imaju antagonistiäśku aktivnost na crth2
WO2009093029A1 (en) * 2008-01-22 2009-07-30 Oxagen Limited Compounds having crth2 antagonist activity
JP2011509990A (ja) * 2008-01-22 2011-03-31 オキサジェン リミテッド Ｃｒｔｈ２アンタゴニスト活性を有する化合物
US20110160249A1 (en) * 2008-05-23 2011-06-30 Schaab Kevin Murray 5-lipoxygenase-activating protein inhibitor
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
WO2012177782A1 (en) * 2011-06-20 2012-12-27 Myrexis, Inc. Compounds and therapeutic uses thereof
GB201322273D0 (en) 2013-12-17 2014-01-29 Atopix Therapeutics Ltd Process
GB201407807D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
GB201407820D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
US11530186B2 (en) * 2018-03-29 2022-12-20 H. Lee Moffitt Cancer Center and Research Center Institute, Inc. Inhibitors for the β-catenin / T-cell factor protein-protein interaction

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL125443C (enExample) * 1963-06-06
US3370063A (en) * 1964-10-05 1968-02-20 Mcneilab Inc Substituted dimethoxy indoles and method of making the same
US3621027A (en) * 1968-03-18 1971-11-16 Endo Lab 1-aminoalkyl-2,6-diaryl 4,5,6,7 tetrahydro-4-oxindales
US3931229A (en) * 1973-08-23 1976-01-06 Warner-Lambert Company 3-Thiomethyl-2[2-(dialkylamino)ethyl]indoles
US4059583A (en) * 1975-11-13 1977-11-22 Mcneil Laboratories, Incorporated Substituted indoles
DK376078A (da) * 1977-08-26 1979-02-27 Wellcome Found Fremgangsmaade til fremstilling af amidazoler
US4140858A (en) * 1977-12-19 1979-02-20 Warner-Lambert Company 3-(1H-imidazol-1-ylmethyl)-2-(disubstitutedaminomethyl)indoles and a method for their production
DE2960547D1 (en) * 1978-02-24 1981-11-05 Pfizer Ltd 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them

Also Published As

Publication number Publication date
DD149525A5 (de) 1981-07-15
HU184727B (en) 1984-10-29
NZ193052A (en) 1984-07-06
DE3008632C2 (enExample) 1988-02-25
DK42580A (da) 1980-09-08
IT8020399A0 (it) 1980-03-06
FI66860B (fi) 1984-08-31
CS253702B2 (en) 1987-12-17
KE3467A (en) 1984-11-09
CA1120479A (en) 1982-03-23
NL8001351A (nl) 1980-09-09
SG67284G (en) 1985-03-15
SU1277894A3 (ru) 1986-12-15
NO152217B (no) 1985-05-13
ES489220A0 (es) 1981-04-01
FR2450832A1 (fr) 1980-10-03
IE49542B1 (en) 1985-10-30
MY8500285A (en) 1985-12-31
AU516957B2 (en) 1981-07-02
IL59524A (en) 1982-11-30
ES8104278A1 (es) 1981-04-01
DE3008632A1 (de) 1980-10-16
JPS6141513B2 (enExample) 1986-09-16
BE882113A (fr) 1980-09-08
CH649546A5 (de) 1985-05-31
FR2450832B1 (enExample) 1983-04-22
ZA801328B (en) 1981-03-25
LU82224A1 (fr) 1980-06-06
ES496889A0 (es) 1982-08-01
HK89884A (en) 1984-11-23
YU41911B (en) 1988-02-29
US4273782A (en) 1981-06-16
GR67237B (enExample) 1981-06-25
FI800672A7 (fi) 1980-09-08
DK151884B (da) 1988-01-11
DK151884C (da) 1988-06-13
IE800453L (en) 1980-09-07
AT375366B (de) 1984-07-25
ATA125780A (de) 1983-12-15
JPS55133380A (en) 1980-10-17
PL222470A1 (enExample) 1980-12-01
PL128296B1 (en) 1984-01-31
IL59524A0 (en) 1980-06-30
PT70914A (en) 1980-04-01
YU61480A (en) 1983-12-31
PH15198A (en) 1982-09-17
ES8205789A1 (es) 1982-08-01
SE440778B (sv) 1985-08-19
IT1218420B (it) 1990-04-19
AR227015A1 (es) 1982-09-15
NO800650L (no) 1980-09-08
AU5623180A (en) 1980-09-11
KR830001928A (ko) 1983-05-19
FI66860C (fi) 1984-12-10
NO152217C (no) 1985-08-21
NL182959C (nl) 1988-06-16
SE8001736L (sv) 1980-09-08

Similar Documents

Publication Publication Date Title
KR850000760B1 (ko) 인돌 유도체의 제조방법
US4602016A (en) N-(phenoxyalkyl)imidazoles as selective inhibitors of the thromboxane synthetase enzyme and pharmaceutical compositions thereof
US4448781A (en) N-Benzyl-imidazoles as selective inhibitors of the thromboxane synthetase enzyme
EP0054417B1 (en) Indole thromboxane synthetase inhibitors, processes for their preparation, and pharmaceutical compositions containing them
JPS5852272A (ja) トロンボキサンシンタ−ゼ阻止作用を有する化合物
US4339583A (en) (Imidazolylmethyl)pyridine compounds as thromboxane synthetase inhibitors
JPH09512275A (ja) 糖尿病および肥満の治療のための選択的β▲下３▼作用物質としての置換スルホンアミド
EP0035863B1 (en) Imidazole derivatives, process for their preparation and pharmaceutical compositions thereof
GB2041363A (en) N-Benzyl-imidazoles
US4451472A (en) Inhibition of thromboxane synthetase with 3-(heteroalkyl)-indolyl-acrylic acid derivatives
US4230714A (en) Imidazole therapeutic agents
GB2065121A (en) Isoquinoline Derivatives
GB2045244A (en) 3-1-(Imidazolylalkyl) indoles
CA2089349C (fr) Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US4888352A (en) 3,4, or 5-aryl-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use
JPH05262736A (ja) フェノキシ酢酸誘導体
JPWO1994026737A1 (ja) イミダゾリルキノキサリンジオン誘導体及びその医薬組成物
FR2827863A1 (fr) Derives d'aminoalkylimidazole, leur preparation et leur utilisation en therapeutique

Legal Events

Date Code Title Description
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1605 Publication of application before grant of patent

St.27 status event code: A-2-2-Q10-Q13-nap-PG1605

PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 19930526

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 19930526

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000