KR840005137A - 티오포름아미드 유도체의 제조방법 - Google Patents

티오포름아미드 유도체의 제조방법 Download PDF

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Publication number
KR840005137A
KR840005137A KR1019830002691A KR830002691A KR840005137A KR 840005137 A KR840005137 A KR 840005137A KR 1019830002691 A KR1019830002691 A KR 1019830002691A KR 830002691 A KR830002691 A KR 830002691A KR 840005137 A KR840005137 A KR 840005137A
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KR
South Korea
Prior art keywords
group
straight
formula
branched chain
chain alkyl
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KR1019830002691A
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English (en)
Inventor
알루 쟝-끌로드 (외 3)
Original Assignee
위베르 고쁘
로오느-푸우랜크 상뜨
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Application filed by 위베르 고쁘, 로오느-푸우랜크 상뜨 filed Critical 위베르 고쁘
Publication of KR840005137A publication Critical patent/KR840005137A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Primary Cells (AREA)
  • Secondary Cells (AREA)

Abstract

내용 없음

Description

티오포름아미드 유도체의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 하기구조식(Ⅱ)의 암모니아 또는 아민을 하기구조식(Ⅲ)의 디티오에스테르와 반응시킨 다음 얻어진 티오포름아미드를 단리하고 임의로 입체이성체를 분리하는 것으로 구성된 하기구조식(I)의 티오포름아미드유도체의 제조방법.
    상기식들에게, R은 수소원자 또는 C1-4의 직쇄 또는 분지쇄알킬기이며, Het는 피리딘-3-일 (C1-4의 직쇄 또는 분지쇄 알킬기나 할로겐원자에 의해 임의로 치환된 것), 퀴놀린-3-일, 피리다진-4-일, 피리미딘-5-일, 티아졸-5-일, 티에노[2,3-b]피리딘-5-일 및 티에노[3,2-b]피리다진-6-일로 부터 선택된 질소원자 1-2개를 함유하는 방향족 특성을 지닌 헤테로사이클기이며; Y는 원자가 결합이나 메틸렌기를 나타내며; R′는 C1-4의 직쇄 또는 분지쇄알킬기나 벤질기 또는 카복시메틸기를 나타낸다.
  2. 제1항에 있어서, 디티오에스테르 반응체가 이미 부분입체 이성체로 분리되어진 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019830002691A 1982-06-17 1983-06-16 티오포름아미드 유도체의 제조방법 KR840005137A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8210614A FR2528849B1 (fr) 1982-06-17 1982-06-17 Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent
FR10,614 1982-06-17

Publications (1)

Publication Number Publication Date
KR840005137A true KR840005137A (ko) 1984-11-03

Family

ID=9275117

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830002691A KR840005137A (ko) 1982-06-17 1983-06-16 티오포름아미드 유도체의 제조방법

Country Status (25)

Country Link
US (2) US4568682A (ko)
EP (1) EP0097584B1 (ko)
JP (1) JPS597188A (ko)
KR (1) KR840005137A (ko)
AT (1) ATE19080T1 (ko)
AU (1) AU562629B2 (ko)
CA (1) CA1209138A (ko)
CS (1) CS236886B2 (ko)
DD (1) DD210043A5 (ko)
DE (1) DE3362906D1 (ko)
DK (1) DK156477C (ko)
ES (1) ES523387A0 (ko)
FI (1) FI831648L (ko)
FR (1) FR2528849B1 (ko)
GR (1) GR79209B (ko)
IE (1) IE55431B1 (ko)
IL (1) IL69006A0 (ko)
MA (1) MA19817A1 (ko)
NO (1) NO832184L (ko)
NZ (1) NZ204614A (ko)
OA (2) OA07450A (ko)
PH (1) PH19061A (ko)
PL (1) PL242538A1 (ko)
PT (1) PT76868B (ko)
ZA (1) ZA834439B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2528849B1 (fr) * 1982-06-17 1985-06-21 Rhone Poulenc Sante Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent
JPS60181866U (ja) * 1984-05-14 1985-12-03 ミサワホ−ム株式会社 同軸ケ−ブル接続端子
FR2573428B1 (fr) * 1984-11-20 1987-01-30 Rhone Poulenc Sante Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent
FR2653662B1 (fr) * 1989-10-31 1994-05-13 Rhone Poulenc Sante Application du n-methyl (pyridyl-3)-2 tetrahydrothiopyranne-carbothioamide-2-oxyde-1 a la preparation de medicaments destines au traitement de l'insuffisance coronarienne.
FR2653770B1 (fr) * 1989-10-31 1992-01-03 Rhone Poulenc Sante Procede de preparation de (pyridyl-3)-2 tetrahydrothiopyrannecarbothioamide-2-oxydes-1-(1r,2r), les (pyridyl-3)-2 tetrhydrothiopyrannecarbothioamide-2-oxydes-1-(1r,2r) ainsi obtenus et les compositions pharmaceutiques qui les contiennent.
JPH04211048A (ja) * 1990-03-05 1992-08-03 Mitsubishi Kasei Corp チオカルバモイルアセトニトリル誘導体
JPH0473463U (ko) * 1990-11-01 1992-06-26
GB9314133D0 (en) * 1993-07-08 1993-08-18 Rhone Poulenc Rorer Ltd New process

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4277484A (en) * 1978-09-20 1981-07-07 Ciba-Geigy Corporation 1-Benzothiepin-4-carboxamides
IE49570B1 (en) * 1979-03-30 1985-10-30 Rhone Poulenc Ind 2-(pyrid-2-yl)tetrahydrothiophene derivatives
FR2452488A1 (fr) * 1979-03-30 1980-10-24 Rhone Poulenc Ind Nouveaux derives du (pyridyl-2)-2 tetrahydrothiophene, leur preparation et les medicaments qui les contiennent
FR2488609A1 (fr) * 1980-08-18 1982-02-19 Rhone Poulenc Ind Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent
EP0048304B1 (en) * 1980-09-24 1984-12-19 Black & Decker Inc. Depth of cut adjustment mechanism for a power planer
FR2511371A1 (fr) * 1981-08-11 1983-02-18 Rhone Poulenc Sante Nouveaux nitriles heterocycliques, leur preparation et leur utilisation pour la preparation de medicaments
FR2528849B1 (fr) * 1982-06-17 1985-06-21 Rhone Poulenc Sante Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent

Also Published As

Publication number Publication date
PT76868B (fr) 1986-02-18
NO832184L (no) 1983-12-19
JPS597188A (ja) 1984-01-14
IL69006A0 (en) 1983-10-31
EP0097584A1 (fr) 1984-01-04
ZA834439B (en) 1984-03-28
DK277683D0 (da) 1983-06-16
AU1582683A (en) 1983-12-22
PL242538A1 (en) 1984-08-13
DK156477B (da) 1989-08-28
IE55431B1 (en) 1990-09-12
FI831648A0 (fi) 1983-05-11
CS236886B2 (en) 1985-05-15
CA1209138A (fr) 1986-08-05
DD210043A5 (de) 1984-05-30
DK156477C (da) 1990-01-29
IE831424L (en) 1983-12-17
DE3362906D1 (en) 1986-05-15
MA19817A1 (fr) 1983-12-31
DK277683A (da) 1983-12-18
PH19061A (en) 1985-12-16
US4751234A (en) 1988-06-14
FR2528849A1 (fr) 1983-12-23
NZ204614A (en) 1986-01-24
FR2528849B1 (fr) 1985-06-21
US4568682A (en) 1986-02-04
PT76868A (fr) 1983-07-01
EP0097584B1 (fr) 1986-04-09
ATE19080T1 (de) 1986-04-15
GR79209B (ko) 1984-10-22
JPH0545592B2 (ko) 1993-07-09
AU562629B2 (en) 1987-06-18
OA07449A (fr) 1984-12-31
ES8403912A1 (es) 1984-04-01
ES523387A0 (es) 1984-04-01
FI831648L (fi) 1983-12-18
OA07450A (fr) 1984-12-31

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