KR840000516A - 아미도벤즈아미드류의 제법 - Google Patents
아미도벤즈아미드류의 제법 Download PDFInfo
- Publication number
- KR840000516A KR840000516A KR1019820003054A KR820003054A KR840000516A KR 840000516 A KR840000516 A KR 840000516A KR 1019820003054 A KR1019820003054 A KR 1019820003054A KR 820003054 A KR820003054 A KR 820003054A KR 840000516 A KR840000516 A KR 840000516A
- Authority
- KR
- South Korea
- Prior art keywords
- group
- formula
- amidobenzamides
- pharmaceutically acceptable
- acceptable salts
- Prior art date
Links
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims 4
- 239000005711 Benzoic acid Substances 0.000 claims 2
- 235000010233 benzoic acid Nutrition 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- -1 methoxyphenyl Chemical group 0.000 claims 2
- 125000004076 pyridyl group Chemical group 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- JFGCGQJHMUYGLU-UHFFFAOYSA-N 2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethanamine Chemical compound CN(C)CC1=CC=C(CSCCN)O1 JFGCGQJHMUYGLU-UHFFFAOYSA-N 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 238000009835 boiling Methods 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 125000006501 nitrophenyl group Chemical group 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 125000003373 pyrazinyl group Chemical group 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 125000001544 thienyl group Chemical group 0.000 claims 1
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (7)
- 하기식(Ⅳ)의 2-(5-디메틸아미노메틸푸란-2-일메틸티오)에틸아민을 0℃ 내지 사용용매의 비점 사이의 온도로 유기 용매중에서 하기식(Ⅴ)의 벤조산 관능 유도체와 반응시키고, 여기에서 수득된 생성물을 약학적으로 허용되는 그의 염으로 전환시켜도 무방한 하기식(Ⅲ)의 아미도벤즈아미드류 및 약학적으로 허용되는 그의 염의 제조방법.
-
- 여기서, A는 CO 또는 SO2이고, B는 탄소원자수 1~6의 알킬기, 페닐기, 피리딜기, 피리딜 1-옥시드기, 피라지닐기 또는 티에닐기를 나타낸다.
- 제1항에 있어서, 바람직한 벤조산 관능유도체가 하기식(Ⅵ)의 화합물임을 특징으로 하는 방법.
-
- 여기서, A 및 B는 전술한 바와같고, Rc는 니트로페닐, 메톡시페닐, 트리틸 또는 벤즈히드릴기를 나타낸다.
- ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8113420A FR2509305B1 (fr) | 1981-07-08 | 1981-07-08 | Benzamides, procede pour leur preparation et compositions pharmaceutiques les renfermant |
| FR8113420 | 1981-07-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR840000516A true KR840000516A (ko) | 1984-02-22 |
Family
ID=9260348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019820003054A KR840000516A (ko) | 1981-07-08 | 1982-07-08 | 아미도벤즈아미드류의 제법 |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5815967A (ko) |
| KR (1) | KR840000516A (ko) |
| CS (1) | CS229935B2 (ko) |
| FR (1) | FR2509305B1 (ko) |
| ZA (1) | ZA824593B (ko) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3964478B2 (ja) * | 1995-06-30 | 2007-08-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬 |
| CN102395270B (zh) * | 2008-07-07 | 2014-11-12 | 法斯根公司 | 化合物、含有其的药物组合物、其使用方法及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2835695A1 (de) * | 1977-08-29 | 1979-03-15 | Yamanouchi Pharma Co Ltd | Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten |
| JPS5681578A (en) * | 1979-12-07 | 1981-07-03 | Shionogi & Co Ltd | Novel thioalkyl amide derivative |
-
1981
- 1981-07-08 FR FR8113420A patent/FR2509305B1/fr not_active Expired
-
1982
- 1982-06-28 ZA ZA824593A patent/ZA824593B/xx unknown
- 1982-07-06 CS CS825164A patent/CS229935B2/cs unknown
- 1982-07-08 KR KR1019820003054A patent/KR840000516A/ko unknown
- 1982-07-08 JP JP57117880A patent/JPS5815967A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA824593B (en) | 1983-04-27 |
| CS229935B2 (en) | 1984-07-16 |
| FR2509305A1 (fr) | 1983-01-14 |
| JPS5815967A (ja) | 1983-01-29 |
| FR2509305B1 (fr) | 1986-04-18 |
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