KR830007071A - 활성화합물 방출효과가 우수한 항진균제 조성물 - Google Patents

활성화합물 방출효과가 우수한 항진균제 조성물

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Publication number
KR830007071A
KR830007071A KR1019810004748A KR810004748A KR830007071A KR 830007071 A KR830007071 A KR 830007071A KR 1019810004748 A KR1019810004748 A KR 1019810004748A KR 810004748 A KR810004748 A KR 810004748A KR 830007071 A KR830007071 A KR 830007071A
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KR
South Korea
Prior art keywords
isopropyl
active compound
weight
antifungal active
composition according
Prior art date
Application number
KR1019810004748A
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English (en)
Other versions
KR880000724B1 (ko
Inventor
폰 비테라 미크로스
뷔켈 칼하인즈
프렘펠 만프레드
헤겔 에릭
Original Assignee
하인즈 게르트 뮐러 및 에리크 데브리쯔
바이엘 아크티엔 게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6118422&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR830007071(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 하인즈 게르트 뮐러 및 에리크 데브리쯔, 바이엘 아크티엔 게젤샤프트 filed Critical 하인즈 게르트 뮐러 및 에리크 데브리쯔
Publication of KR830007071A publication Critical patent/KR830007071A/ko
Application granted granted Critical
Publication of KR880000724B1 publication Critical patent/KR880000724B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Stereophonic Arrangements (AREA)
  • Body Structure For Vehicles (AREA)
  • Catching Or Destruction (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

내용 없음

Description

활성화합물 방출효과가 우수한 항진균제 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (9)

1개 또는 그 이상의 제형보조에 이외에 3 내지 5% 벤질알콜과 2.5 내지 20%의 확산제를 함유하는 항진균 활성화합물의 조성물.
제1항에 있어서 항진균활성 화합물로서 이미다졸유도체 또는 트리아졸유도체를 사용하는 조성물.
제2항에 있어서 항진균활성 화합물이 다음일반식을 갖는 크로트리마졸인 조성물.
제2항에 있어서, 항진균활성 화합물이 다음일반식을 갖는 트리폰아졸인 조성물.
제2항에 있어서 항진균활성 화합물이 다음 일반식을 갖는 롬바졸인 조성물.
제1항이나 제 5항중 어느 하나에 있어서 항진균활성 화합물이 0.05 내지 1중량%로 존재하는 조성물.
제6항에 있어서 항진균활성 화합물 0.1 내지 1중량%로 존재하는 조성물.
제1항이나 제 7항중 어느 하나에 있어서 확산제를 이소프로필 미리스테이트, 이소프로필 팔미테이트, C12내지 C18사슬길이 포호지방알콜의 카르릴/카프르산 에스테르, 납질 지방산 에스테르, 실리콘오일 및 이소프로필 미리스테이트/이소프로필 스테아레이트/이소프로필 팔미테이트 혼합물 중에서 선택한 조성물.
제1항에 있어서, 전술한 실시예 1 내지 15중 어느 하나에 특정한 조성물.
※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019810004748A 1980-12-05 1981-12-05 활성화합물의 방출성이 우수한 항진균 조성물의 제조방법 KR880000724B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19803045913 DE3045913A1 (de) 1980-12-05 1980-12-05 Antimykotische mittel mit hoher wirkstoff-freisetzung
DEP3045913.3 1980-12-05

Publications (2)

Publication Number Publication Date
KR830007071A true KR830007071A (ko) 1983-10-12
KR880000724B1 KR880000724B1 (ko) 1988-04-29

Family

ID=6118422

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810004748A KR880000724B1 (ko) 1980-12-05 1981-12-05 활성화합물의 방출성이 우수한 항진균 조성물의 제조방법

Country Status (13)

Country Link
EP (1) EP0054205B1 (ko)
JP (1) JPS57120516A (ko)
KR (1) KR880000724B1 (ko)
AT (1) ATE11219T1 (ko)
AU (1) AU546451B2 (ko)
CA (1) CA1180661A (ko)
DE (2) DE3045913A1 (ko)
DK (1) DK538481A (ko)
ES (1) ES8400241A1 (ko)
FI (1) FI813883L (ko)
IL (1) IL64434A0 (ko)
NO (1) NO158922C (ko)
ZA (1) ZA818430B (ko)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH655656B (ko) * 1982-10-07 1986-05-15
DE3244027A1 (de) * 1982-11-27 1984-05-30 Bayer Ag, 5090 Leverkusen Antimykotische mittel mit hoher wirkstoff-freisetzung in form von gelsystemen
DE3311700A1 (de) * 1983-03-30 1984-10-04 Bayer Ag Antimykotische mittel mit hoher wirkstoff-freisetzung in form von loesung und spray
DE3311701A1 (de) * 1983-03-30 1984-10-04 Bayer Ag Antimykotische mittel mit hoher wirkstoff-freisetzung in form von creme
DE3323832A1 (de) * 1983-07-01 1985-01-03 Troponwerke Gmbh & Co Kg Etofenamat-zubereitung
DE3323833A1 (de) * 1983-07-01 1985-01-03 Troponwerke Gmbh & Co Kg Etofenamat-zubereitung
US4731384A (en) * 1983-07-01 1988-03-15 Troponwerke Gmbh & Co, Kg Etofenamate formulation
JPS6058914A (ja) * 1983-09-12 1985-04-05 Shionogi & Co Ltd イミダゾ−ル系抗真菌性外用ゲル製剤
CS253719B2 (en) * 1984-03-07 1987-12-17 Janssen Pharmaceutica Nv Emulsible concentrate with fungicide activity and process for preparing thereof
DE3520098A1 (de) * 1985-06-05 1986-12-11 Bayer Ag, 5090 Leverkusen Azolderivate enthaltende formulierungen sowie ihre verwendung zur atraumatischen nagelentfernung
JPS6261915A (ja) * 1985-09-10 1987-03-18 Taisho Pharmaceut Co Ltd 抗真菌外用製剤
DE3600947A1 (de) * 1986-01-15 1987-07-16 Kali Chemie Pharma Gmbh Antimykotische emulsionen
HU200914B (en) * 1987-03-09 1990-09-28 Horvath Gyoengyi Lengyelne Process for producing new medical dosage unit suitable for local treatment of fungus infection of nails
JPH01246219A (ja) * 1988-03-25 1989-10-02 Nippon Nohyaku Co Ltd 抗真菌外用クリーム組成物
JPH0725675B2 (ja) * 1989-05-08 1995-03-22 ホーユー株式会社 液状真菌症治療剤
YU2792A (sh) * 1991-01-19 1995-01-31 Hoechst A Ktiengesellschaft Disperzije finih čestica, antihelmintno efikasnih derivata, benzimidazola ili benztiazola ili pro-benzimidazola u vodi
KR20020045152A (ko) * 2000-12-08 2002-06-19 류정열 호스클램프용 클램프홀더
WO2006005120A1 (en) * 2004-07-09 2006-01-19 Pandura Farms Pty Ltd Sequential cooling methods and apparatus
US9687429B2 (en) 2007-06-20 2017-06-27 The Trustees Of Columbia University In The City Of New York Antimicrobial compositions containing low concentrations of botanicals
US9511040B2 (en) 2007-06-20 2016-12-06 The Trustees Of Columbia University In The City Of New York Skin and surface disinfectant compositions containing botanicals
WO2008157092A1 (en) 2007-06-20 2008-12-24 The Trustees Of Columbia University In The City Of New York Bio-film resistant surfaces
US9981069B2 (en) 2007-06-20 2018-05-29 The Trustees Of Columbia University In The City Of New York Bio-film resistant surfaces
JP2012532141A (ja) * 2009-06-30 2012-12-13 ザ トラスティース オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク 植物性成分を含有する抗微生物／防腐組成物
US9968101B2 (en) 2011-11-03 2018-05-15 The Trustees Of Columbia University In The City Of New York Botanical antimicrobial compositions
EP2773334B1 (en) 2011-11-03 2019-08-28 The Trustees of Columbia University in the City of New York Composition with sustained antimicrobial activity
WO2013086094A1 (en) 2011-12-06 2013-06-13 The Trustees Of Columbia University In The City Of New York Broad spectrum natural preservative composition
CN111423328B (zh) * 2020-04-02 2022-04-15 广州隽沐生物科技股份有限公司 油酸癸酯的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3502594A (en) * 1965-12-28 1970-03-24 Gerhard W Ahrens Synergistic antioxidant composition for natural oleaginous materials
US3483008A (en) * 1966-08-01 1969-12-09 Daniel A Naeve Method of preparing a water-soluble protein lotion
DE2333355C2 (de) * 1973-06-30 1984-01-19 Bayer Ag, 5090 Leverkusen Antimikrobielle Mittel
DE2430039C2 (de) * 1974-06-22 1983-11-10 Bayer Ag, 5090 Leverkusen Climbazol in kosmetischen Mitteln
DE2461406C2 (de) * 1974-12-24 1984-06-14 Bayer Ag, 5090 Leverkusen Azolyl-(1)-methane und deren Salze, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE2628421A1 (de) * 1976-06-24 1978-01-05 Bayer Ag Antimikrobielle mittel
DE2811916A1 (de) * 1978-03-18 1979-09-27 Bayer Ag Antimikrobielle mittel

Also Published As

Publication number Publication date
EP0054205B1 (de) 1985-01-16
DE3045913A1 (de) 1982-07-08
ES507726A0 (es) 1983-11-01
CA1180661A (en) 1985-01-08
FI813883L (fi) 1982-06-06
AU7826381A (en) 1982-06-10
ZA818430B (en) 1982-11-24
ATE11219T1 (de) 1985-02-15
IL64434A0 (en) 1982-03-31
NO158922C (no) 1988-11-23
EP0054205A1 (de) 1982-06-23
JPS57120516A (en) 1982-07-27
NO813930L (no) 1982-06-07
DE3168402D1 (en) 1985-02-28
DK538481A (da) 1982-06-06
ES8400241A1 (es) 1983-11-01
KR880000724B1 (ko) 1988-04-29
AU546451B2 (en) 1985-09-05
JPH0380775B2 (ko) 1991-12-26
NO158922B (no) 1988-08-08

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