KR20240027603A - 바이사이클릭 피페라진 고리 또는 이의 염을 갖는 벤조옥사졸 유도체의 제조방법 및 이의 원료의 제조방법 - Google Patents
바이사이클릭 피페라진 고리 또는 이의 염을 갖는 벤조옥사졸 유도체의 제조방법 및 이의 원료의 제조방법 Download PDFInfo
- Publication number
- KR20240027603A KR20240027603A KR1020237043708A KR20237043708A KR20240027603A KR 20240027603 A KR20240027603 A KR 20240027603A KR 1020237043708 A KR1020237043708 A KR 1020237043708A KR 20237043708 A KR20237043708 A KR 20237043708A KR 20240027603 A KR20240027603 A KR 20240027603A
- Authority
- KR
- South Korea
- Prior art keywords
- formula
- group
- compound
- compound represented
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Health & Medical Sciences (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JPJP-P-2021-108230 | 2021-06-30 | ||
| JP2021108230 | 2021-06-30 | ||
| PCT/JP2022/026168 WO2023277120A1 (ja) | 2021-06-30 | 2022-06-30 | 二環性ピペラジン環を有するベンゾオキサゾール誘導体又はその塩の製造方法、並びに、その原料の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20240027603A true KR20240027603A (ko) | 2024-03-04 |
Family
ID=84691891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237043708A Pending KR20240027603A (ko) | 2021-06-30 | 2022-06-30 | 바이사이클릭 피페라진 고리 또는 이의 염을 갖는 벤조옥사졸 유도체의 제조방법 및 이의 원료의 제조방법 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20240309010A1 (https=) |
| EP (1) | EP4365174A4 (https=) |
| JP (2) | JP7476431B2 (https=) |
| KR (1) | KR20240027603A (https=) |
| CN (2) | CN121873082A (https=) |
| AR (1) | AR126290A1 (https=) |
| AU (1) | AU2022300611A1 (https=) |
| BR (1) | BR112023025934A2 (https=) |
| CA (1) | CA3223354A1 (https=) |
| IL (1) | IL309736A (https=) |
| MX (1) | MX2023014123A (https=) |
| WO (1) | WO2023277120A1 (https=) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018124060A1 (ja) | 2016-12-26 | 2018-07-05 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 新規化合物及びその薬理的に許容される塩 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9890142B2 (en) * | 2013-07-10 | 2018-02-13 | Meiji Seika Pharma Co., Ltd. | PDE4 inhibitor |
| KR102931303B1 (ko) * | 2018-06-27 | 2026-02-25 | 메이지 세이카 파루마 가부시키가이샤 | 염증성 질환, 자가면역 질환, 섬유화 질환 및 암 질환의 치료제 |
| JP2021155336A (ja) * | 2018-06-27 | 2021-10-07 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 新規ｐｄｅ４阻害剤 |
-
2022
- 2022-06-30 MX MX2023014123A patent/MX2023014123A/es unknown
- 2022-06-30 JP JP2023532045A patent/JP7476431B2/ja active Active
- 2022-06-30 CN CN202610020318.9A patent/CN121873082A/zh active Pending
- 2022-06-30 IL IL309736A patent/IL309736A/en unknown
- 2022-06-30 CA CA3223354A patent/CA3223354A1/en active Pending
- 2022-06-30 KR KR1020237043708A patent/KR20240027603A/ko active Pending
- 2022-06-30 WO PCT/JP2022/026168 patent/WO2023277120A1/ja not_active Ceased
- 2022-06-30 EP EP22833266.4A patent/EP4365174A4/en active Pending
- 2022-06-30 BR BR112023025934A patent/BR112023025934A2/pt unknown
- 2022-06-30 AU AU2022300611A patent/AU2022300611A1/en active Pending
- 2022-06-30 AR ARP220101722A patent/AR126290A1/es unknown
- 2022-06-30 US US18/575,158 patent/US20240309010A1/en active Pending
- 2022-06-30 CN CN202280035356.1A patent/CN117295744A/zh active Pending
-
2024
- 2024-04-17 JP JP2024067062A patent/JP7839217B2/ja active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018124060A1 (ja) | 2016-12-26 | 2018-07-05 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 新規化合物及びその薬理的に許容される塩 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7839217B2 (ja) | 2026-04-01 |
| CN117295744A (zh) | 2023-12-26 |
| EP4365174A4 (en) | 2025-07-02 |
| US20240309010A1 (en) | 2024-09-19 |
| MX2023014123A (es) | 2023-12-12 |
| BR112023025934A2 (pt) | 2024-02-27 |
| JP7476431B2 (ja) | 2024-04-30 |
| EP4365174A1 (en) | 2024-05-08 |
| AU2022300611A1 (en) | 2024-01-25 |
| WO2023277120A1 (ja) | 2023-01-05 |
| CN121873082A (zh) | 2026-04-17 |
| AR126290A1 (es) | 2023-10-04 |
| TW202311242A (zh) | 2023-03-16 |
| JP2024096941A (ja) | 2024-07-17 |
| JPWO2023277120A1 (https=) | 2023-01-05 |
| IL309736A (en) | 2024-02-01 |
| CA3223354A1 (en) | 2023-01-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2018337597B2 (en) | Process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7- yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives | |
| US20110003999A1 (en) | Process for Preparing Substituted Biphenylanilides | |
| TW202026280A (zh) | 6-(2,4-二氯苯基)-5-[4-[(3s)-1-(3-氟丙基)吡咯啶-3-基]氧基苯基]-8,9-二氫-7h-苯並[7]輪烯-2-甲酸甲酯的鹽及其製備方法 | |
| CN103384663B (zh) | 用于制备安塞曲匹及其衍生物的中间体的合成 | |
| CN113767094B (zh) | 3-甲基-1,2,4-噻二唑-5-碳酰肼及其甲基-d3氘代形式的合成 | |
| CN111315742A (zh) | 制备氨基嘧啶衍生物的改善方法 | |
| CN110105305B (zh) | 过渡金属催化的c-h活化/环合合成1,2-苯并噻嗪衍生物的绿色合成方法 | |
| CN108658841B (zh) | 一种咔唑类化合物及其制备方法 | |
| KR102743629B1 (ko) | 선택적 에스트로겐 수용체 분해제의 제조 방법 | |
| AU728147B2 (en) | Method for the preparation of alpha-bromo-lactam derivatives | |
| KR20240027603A (ko) | 바이사이클릭 피페라진 고리 또는 이의 염을 갖는 벤조옥사졸 유도체의 제조방법 및 이의 원료의 제조방법 | |
| JP3526310B2 (ja) | 不斉還元方法 | |
| US20020016512A1 (en) | Heterogeneously catalyzed process for cross coupling aryl chlorides with aryl boronic acids | |
| FI83643C (fi) | Foerfarande foer framstaellning av dihydrokinolinkarboxylsyror. | |
| TWI915570B (zh) | 具有二環性哌嗪環之苯并噁唑衍生物或其鹽之製造方法以及其原料之製造方法 | |
| RU2858377C2 (ru) | Способ получения производного бензоксазола, содержащего бициклическое пиперазиновое кольцо, или его соли и способ получения исходного вещества для него | |
| US20120016152A1 (en) | Process for the preparation of 4`-haloalkylbiphenyl-2-carboxylic acids | |
| CN101952253A (zh) | 取代的酰联苯胺的制备方法 | |
| CN119638647A (zh) | 制备氧杂环丁烷-2-基甲胺或其盐的方法 | |
| CN102391285A (zh) | 一种苯并[f]噻吩并[3,2-b]喹啉衍生物的合成方法 | |
| CN116283765A (zh) | 一种不活泼烯烃的氯三氟甲基化方法 | |
| WO2010008727A1 (en) | Asymmetric synthesis of allyl or allene oxindoles | |
| JP2000007606A (ja) | ７−（２−フルオロフェニル）−１−ベンゾスベロンの製造法 | |
| CN111454160A (zh) | 一种β-三氟甲基苯胺类化合物及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20231218 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20250407 Comment text: Request for Examination of Application |