IL309736A - A method for producing a derivative of benzoxazole having a bicyclic piperazine ring or a salt thereof and a method for producing a substance from it - Google Patents

A method for producing a derivative of benzoxazole having a bicyclic piperazine ring or a salt thereof and a method for producing a substance from it

Info

Publication number
IL309736A
IL309736A IL309736A IL30973623A IL309736A IL 309736 A IL309736 A IL 309736A IL 309736 A IL309736 A IL 309736A IL 30973623 A IL30973623 A IL 30973623A IL 309736 A IL309736 A IL 309736A
Authority
IL
Israel
Prior art keywords
producing
salt
piperazine ring
benzoxazole derivative
bicyclic piperazine
Prior art date
Application number
IL309736A
Other languages
English (en)
Hebrew (he)
Inventor
Takeshi Tsumura
Satoshi ISSHIKI
Masayuki Okue
Toshiro Sasaki
Kenichi Fushihara
Shinsuke Mouri
Original Assignee
Meiji Seika Pharma Co Ltd
Takeshi Tsumura
Satoshi ISSHIKI
Masayuki Okue
Toshiro Sasaki
Kenichi Fushihara
Shinsuke Mouri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Pharma Co Ltd, Takeshi Tsumura, Satoshi ISSHIKI, Masayuki Okue, Toshiro Sasaki, Kenichi Fushihara, Shinsuke Mouri filed Critical Meiji Seika Pharma Co Ltd
Publication of IL309736A publication Critical patent/IL309736A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995Pyrazines or piperazines forming part of bridged ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Health & Medical Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
IL309736A 2021-06-30 2022-06-30 A method for producing a derivative of benzoxazole having a bicyclic piperazine ring or a salt thereof and a method for producing a substance from it IL309736A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021108230 2021-06-30
PCT/JP2022/026168 WO2023277120A1 (ja) 2021-06-30 2022-06-30 二環性ピペラジン環を有するベンゾオキサゾール誘導体又はその塩の製造方法、並びに、その原料の製造方法

Publications (1)

Publication Number Publication Date
IL309736A true IL309736A (en) 2024-02-01

Family

ID=84691891

Family Applications (1)

Application Number Title Priority Date Filing Date
IL309736A IL309736A (en) 2021-06-30 2022-06-30 A method for producing a derivative of benzoxazole having a bicyclic piperazine ring or a salt thereof and a method for producing a substance from it

Country Status (12)

Country Link
US (1) US20240309010A1 (https=)
EP (1) EP4365174A4 (https=)
JP (2) JP7476431B2 (https=)
KR (1) KR20240027603A (https=)
CN (2) CN121873082A (https=)
AR (1) AR126290A1 (https=)
AU (1) AU2022300611A1 (https=)
BR (1) BR112023025934A2 (https=)
CA (1) CA3223354A1 (https=)
IL (1) IL309736A (https=)
MX (1) MX2023014123A (https=)
WO (1) WO2023277120A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9890142B2 (en) * 2013-07-10 2018-02-13 Meiji Seika Pharma Co., Ltd. PDE4 inhibitor
MX389276B (es) * 2016-12-26 2025-03-20 Meiji Seika Pharma Co Ltd Compuesto novedoso y sal de este aceptable desde el punto de vista farmacologico.
KR102931303B1 (ko) * 2018-06-27 2026-02-25 메이지 세이카 파루마 가부시키가이샤 염증성 질환, 자가면역 질환, 섬유화 질환 및 암 질환의 치료제
JP2021155336A (ja) * 2018-06-27 2021-10-07 Meiji Seikaファルマ株式会社 新規pde4阻害剤

Also Published As

Publication number Publication date
JP7839217B2 (ja) 2026-04-01
CN117295744A (zh) 2023-12-26
EP4365174A4 (en) 2025-07-02
US20240309010A1 (en) 2024-09-19
KR20240027603A (ko) 2024-03-04
MX2023014123A (es) 2023-12-12
BR112023025934A2 (pt) 2024-02-27
JP7476431B2 (ja) 2024-04-30
EP4365174A1 (en) 2024-05-08
AU2022300611A1 (en) 2024-01-25
WO2023277120A1 (ja) 2023-01-05
CN121873082A (zh) 2026-04-17
AR126290A1 (es) 2023-10-04
TW202311242A (zh) 2023-03-16
JP2024096941A (ja) 2024-07-17
JPWO2023277120A1 (https=) 2023-01-05
CA3223354A1 (en) 2023-01-05

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