KR20230080414A - 샘플에서 하나 이상의 표적 분석물을 검출하기 위한 키트 및 이의 제조 및 사용 방법 - Google Patents

샘플에서 하나 이상의 표적 분석물을 검출하기 위한 키트 및 이의 제조 및 사용 방법 Download PDF

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KR20230080414A
KR20230080414A KR1020237011128A KR20237011128A KR20230080414A KR 20230080414 A KR20230080414 A KR 20230080414A KR 1020237011128 A KR1020237011128 A KR 1020237011128A KR 20237011128 A KR20237011128 A KR 20237011128A KR 20230080414 A KR20230080414 A KR 20230080414A
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sequence
oligonucleotide
detection
seq
capture
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Korean (ko)
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존 켄텐
갈리나 니콜렌코
세스 비 하킨스
티모시 제이 브레이크
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메소 스케일 테크놀러지즈, 엘엘시
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
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    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/30—Phosphoric diester hydrolysing, i.e. nuclease
    • C12Q2521/327—RNAse, e.g. RNAseH
    • C—CHEMISTRY; METALLURGY
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    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/50—Other enzymatic activities
    • C12Q2521/501—Ligase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/121—Modifications characterised by incorporating both deoxyribonucleotides and ribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/161—Modifications characterised by incorporating target specific and non-target specific sites
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    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/125—Rolling circle
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2533/00—Reactions characterised by the enzymatic reaction principle used
    • C12Q2533/10—Reactions characterised by the enzymatic reaction principle used the purpose being to increase the length of an oligonucleotide strand
    • C12Q2533/107—Probe or oligonucleotide ligation
    • C—CHEMISTRY; METALLURGY
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/125—Sandwich assay format
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2561/00—Nucleic acid detection characterised by assay method
    • C12Q2561/108—Hybridisation protection assay [HPA]
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    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/113—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being electroactive, e.g. redox labels
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
    • C12Q2565/518—Detection characterised by immobilisation to a surface characterised by the immobilisation of the nucleic acid sample or target

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
KR1020237011128A 2020-09-02 2021-09-02 샘플에서 하나 이상의 표적 분석물을 검출하기 위한 키트 및 이의 제조 및 사용 방법 Pending KR20230080414A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063073635P 2020-09-02 2020-09-02
US63/073,635 2020-09-02
PCT/US2021/048854 WO2022051485A2 (en) 2020-09-02 2021-09-02 Kits for detecting one or more target analytes in a sample and methods of making and using the same

Publications (1)

Publication Number Publication Date
KR20230080414A true KR20230080414A (ko) 2023-06-07

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KR1020237011128A Pending KR20230080414A (ko) 2020-09-02 2021-09-02 샘플에서 하나 이상의 표적 분석물을 검출하기 위한 키트 및 이의 제조 및 사용 방법

Country Status (9)

Country Link
US (1) US20240368676A1 (https=)
EP (1) EP4208566A2 (https=)
JP (1) JP2023539360A (https=)
KR (1) KR20230080414A (https=)
CN (1) CN116507738A (https=)
AU (1) AU2021338303A1 (https=)
CA (1) CA3193739A1 (https=)
IL (1) IL300973A (https=)
WO (1) WO2022051485A2 (https=)

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CN120098057A (zh) 2019-03-01 2025-06-06 中尺度技术有限责任公司 用于免疫方法的被电化学发光标记的探针、使用这类探针的方法和包含这类探针的试剂盒
KR20240026443A (ko) * 2021-04-26 2024-02-28 메소 스케일 테크놀러지즈, 엘엘시 다중 검정 플레이트 및 제조 방법
CN116144734B (zh) * 2023-02-23 2024-02-13 纳昂达(南京)生物科技有限公司 甲基化转化组合物及其应用
CN120442620B (zh) * 2025-07-11 2025-10-31 良渚实验室 用于蛋白检测体系的寡核苷酸阻断剂及降低基于邻位反应的超灵敏蛋白检测体系背景的方法

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JPH0534345A (ja) 1991-02-19 1993-02-09 Tdk Corp 化学発光を利用する抗原・抗体の測定方法
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AU2021338303A1 (en) 2023-04-20
WO2022051485A3 (en) 2023-03-30
CA3193739A1 (en) 2022-03-10
US20240368676A1 (en) 2024-11-07
EP4208566A2 (en) 2023-07-12
IL300973A (en) 2023-04-01
CN116507738A (zh) 2023-07-28
JP2023539360A (ja) 2023-09-13
WO2022051485A2 (en) 2022-03-10

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