KR20230058167A - 조작된 자연 살해 세포의 향상된 증폭 및 세포 독성 및 그의 용도 - Google Patents
조작된 자연 살해 세포의 향상된 증폭 및 세포 독성 및 그의 용도 Download PDFInfo
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| PCT/US2021/071330 WO2022051749A1 (en) | 2020-09-02 | 2021-08-31 | Enhanced expansion and cytotoxicity of engineered natural killer cells and uses thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024258127A1 (ko) * | 2023-06-12 | 2024-12-19 | 한국화학연구원 | Nk 세포의 증식 촉진 또는 활성화용 조성물 및 그의 용도 |
| WO2025220989A1 (ko) * | 2024-04-16 | 2025-10-23 | 주식회사 유씨아이테라퓨틱스 | 자연살해세포의 증폭 및 형질 도입 효율 증진용 피더 세포 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015259877B2 (en) | 2014-05-15 | 2021-02-25 | National University Of Singapore | Modified natural killer cells and uses thereof |
| KR102660336B1 (ko) | 2017-03-27 | 2024-04-26 | 내셔널 유니버시티 오브 싱가포르 | 절단된 nkg2d 키메라 수용체 및 자연 살해 세포 면역요법에서의 그의 용도 |
| AU2019219454A1 (en) | 2018-02-09 | 2020-08-27 | National University Of Singapore | Activating chimeric receptors and uses thereof in natural killer cell immunotherapy |
| CN112055717B (zh) | 2018-04-02 | 2024-04-26 | 新加坡国立大学 | 用在免疫细胞中表达的膜结合抗细胞因子非信号传导粘合剂中和人细胞因子 |
| EP3844186A4 (en) | 2018-08-29 | 2022-08-17 | National University of Singapore | METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS |
| US12590148B2 (en) | 2018-11-26 | 2026-03-31 | Nkarta, Inc. | Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy |
| AU2020232691B2 (en) | 2019-03-05 | 2023-06-29 | Nkarta, Inc. | CD19-directed chimeric antigen receptors and uses thereof in immunotherapy |
| EP4649139A1 (en) * | 2023-02-01 | 2025-11-19 | Nkarta, Inc. | Methods for expanding immune cells and related compositions and uses thereof |
| KR102669705B1 (ko) * | 2023-02-24 | 2024-06-10 | 이엔셀 주식회사 | 제대혈 유래 자연 살해 세포의 확장배양방법 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109844099B (zh) * | 2016-07-25 | 2024-01-02 | 美国政府(由卫生和人类服务部的部长所代表) | 产生经修饰的自然杀伤细胞的方法及使用方法 |
| US10300089B2 (en) * | 2016-11-08 | 2019-05-28 | University Of Central Florida Research Foundation, Inc. | Methods for high scale therapeutic production of memory NK cells |
| KR102746901B1 (ko) * | 2017-03-03 | 2024-12-26 | 옵시디안 테라퓨틱스, 인크. | Cd19 조성물 및 면역요법을 위한 방법 |
| MX2019011570A (es) * | 2017-03-27 | 2019-11-18 | Nat Univ Singapore | Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales. |
| JP7273421B2 (ja) * | 2018-02-21 | 2023-05-15 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用 |
| US12590148B2 (en) * | 2018-11-26 | 2026-03-31 | Nkarta, Inc. | Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy |
| MX2022001255A (es) * | 2019-07-31 | 2022-05-10 | Nkarta Inc | Metodos y composiciones para la expansion y la citotoxicidad mejoradas de las celulas asesinas naturales. |
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- 2021-08-31 KR KR1020237011188A patent/KR20230058167A/ko active Pending
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024258127A1 (ko) * | 2023-06-12 | 2024-12-19 | 한국화학연구원 | Nk 세포의 증식 촉진 또는 활성화용 조성물 및 그의 용도 |
| WO2025220989A1 (ko) * | 2024-04-16 | 2025-10-23 | 주식회사 유씨아이테라퓨틱스 | 자연살해세포의 증폭 및 형질 도입 효율 증진용 피더 세포 |
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| EP4204560A1 (en) | 2023-07-05 |
| AU2021337000A9 (en) | 2023-07-13 |
| EP4204560A4 (en) | 2024-10-16 |
| AU2021337000A1 (en) | 2023-05-11 |
| IL300903A (en) | 2023-04-01 |
| US20230265390A1 (en) | 2023-08-24 |
| JP2023539361A (ja) | 2023-09-13 |
| CN116568805A (zh) | 2023-08-08 |
| JP7824934B2 (ja) | 2026-03-05 |
| WO2022051749A1 (en) | 2022-03-10 |
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Patent event date: 20230331 Patent event code: PA01051R01D Comment text: International Patent Application |
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