KR20230003433A - 유전자에 기반한 염증성 장 질환의 진단 - Google Patents

유전자에 기반한 염증성 장 질환의 진단 Download PDF

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KR20230003433A
KR20230003433A KR1020227044940A KR20227044940A KR20230003433A KR 20230003433 A KR20230003433 A KR 20230003433A KR 1020227044940 A KR1020227044940 A KR 1020227044940A KR 20227044940 A KR20227044940 A KR 20227044940A KR 20230003433 A KR20230003433 A KR 20230003433A
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더모트 피 맥거번
달린 리
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세다르스-신나이 메디칼 센터
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Application filed by 세다르스-신나이 메디칼 센터 filed Critical 세다르스-신나이 메디칼 센터
Priority to KR1020247019512A priority Critical patent/KR20240095363A/ko
Publication of KR20230003433A publication Critical patent/KR20230003433A/ko
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
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  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
KR1020227044940A 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단 Ceased KR20230003433A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247019512A KR20240095363A (ko) 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662339357P 2016-05-20 2016-05-20
US62/339,357 2016-05-20
PCT/US2017/033625 WO2017201461A1 (en) 2016-05-20 2017-05-19 Diagnosis of inflammatory bowel disease based on genes
KR1020227003985A KR102481305B1 (ko) 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단

Related Parent Applications (1)

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KR1020227003985A Division KR102481305B1 (ko) 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단

Related Child Applications (1)

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KR1020247019512A Division KR20240095363A (ko) 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단

Publications (1)

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KR20230003433A true KR20230003433A (ko) 2023-01-05

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KR1020227044940A Ceased KR20230003433A (ko) 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단
KR1020187037151A Ceased KR20190016972A (ko) 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단
KR1020247019512A Ceased KR20240095363A (ko) 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단
KR1020227003985A Active KR102481305B1 (ko) 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단

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KR1020187037151A Ceased KR20190016972A (ko) 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단
KR1020247019512A Ceased KR20240095363A (ko) 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단
KR1020227003985A Active KR102481305B1 (ko) 2016-05-20 2017-05-19 유전자에 기반한 염증성 장 질환의 진단

Country Status (6)

Country Link
US (2) US11549146B2 (enExample)
EP (1) EP3458466B1 (enExample)
JP (4) JP7475811B2 (enExample)
KR (4) KR20230003433A (enExample)
CN (2) CN109476698B (enExample)
WO (1) WO2017201461A1 (enExample)

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CN109476698B (zh) * 2016-05-20 2023-10-17 西达-赛奈医疗中心 基于基因的炎性肠病诊断
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CN114375339A (zh) 2019-05-14 2022-04-19 普罗米修斯生物科学公司 Tl1a患者选择方法、系统和装置
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CN115851911B (zh) * 2022-11-25 2025-10-24 南京鼓楼医院 一种用于鉴别狼疮性肾炎的尿液外泌体tsRNA标志物和探针及其应用
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KR20220025122A (ko) 2022-03-03
JP7475811B2 (ja) 2024-04-30
US20230366028A1 (en) 2023-11-16
EP3458466B1 (en) 2024-08-07
KR102481305B1 (ko) 2022-12-26
JP2026048696A (ja) 2026-03-17
JP7392020B2 (ja) 2023-12-05
CN109476698A (zh) 2019-03-15
CN117286238A (zh) 2023-12-26
EP3458466A1 (en) 2019-03-27
CN109476698B (zh) 2023-10-17
US11549146B2 (en) 2023-01-10
WO2017201461A1 (en) 2017-11-23
EP3458466A4 (en) 2020-03-04
US12545959B2 (en) 2026-02-10
KR20240095363A (ko) 2024-06-25
KR20190016972A (ko) 2019-02-19
JP2019516375A (ja) 2019-06-20
US20190194754A1 (en) 2019-06-27
JP2022095688A (ja) 2022-06-28
JP2024037945A (ja) 2024-03-19

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