KR20220119421A - 펩타이드 화합물의 합성법 - Google Patents
펩타이드 화합물의 합성법 Download PDFInfo
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- KR20220119421A KR20220119421A KR1020227024736A KR20227024736A KR20220119421A KR 20220119421 A KR20220119421 A KR 20220119421A KR 1020227024736 A KR1020227024736 A KR 1020227024736A KR 20227024736 A KR20227024736 A KR 20227024736A KR 20220119421 A KR20220119421 A KR 20220119421A
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
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| WO2018225851A1 (ja) | 2017-06-09 | 2018-12-13 | 中外製薬株式会社 | Ｎ－置換アミノ酸を含むペプチドの合成方法 |
| EP3878836B1 (en) | 2018-11-07 | 2025-07-23 | Chugai Seiyaku Kabushiki Kaisha | O-substituted serine derivative production method |
| KR20210139366A (ko) | 2019-03-15 | 2021-11-22 | 추가이 세이야쿠 가부시키가이샤 | 방향족 아미노산 유도체의 제조 방법 |
| US12404299B2 (en) | 2019-11-07 | 2025-09-02 | Chugai Seiyaku Kabushiki Kaisha | Method for producing peptide compound comprising highly sterically hindered amino acid |
| PE20221323A1 (es) | 2019-11-07 | 2022-09-09 | Chugai Pharmaceutical Co Ltd | Compuesto de peptidos ciclicos que tiene accion inhibidora de kras |
| TW202309065A (zh) | 2021-05-07 | 2023-03-01 | 日商中外製藥股份有限公司 | 包含n-取代胺基酸殘基之環狀化合物的製造方法 |
| CA3256645A1 (en) | 2022-05-06 | 2025-04-23 | Chugai Seiyaku Kabushiki Kaisha | CYCLIC COMPOUND HAVING A SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS |
| CN114920669A (zh) * | 2022-06-28 | 2022-08-19 | 吉尔多肽生物制药(大连市)有限公司 | 一种n-甲基-n-苄氧羰基-l-天门冬氨酸（4-叔丁酯）二环己胺盐的合成方法 |
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| EP4596567A1 (en) | 2022-11-01 | 2025-08-06 | Chugai Seiyaku Kabushiki Kaisha | Method for removing dibenzofulvene or dibenzofulvene derivative |
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| WO2025070753A1 (ja) | 2023-09-28 | 2025-04-03 | 中外製薬株式会社 | 混合酸無水物法を用いたペプチド化合物の製造方法 |
| CN121889409A (zh) | 2023-12-27 | 2026-04-17 | 中外制药株式会社 | 用于使用独立型缩合剂生产肽化合物的方法 |
| CN119613485B (zh) * | 2024-12-16 | 2025-10-28 | 中原食品实验室 | 一种二肽-2的制备方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JPS5212371B2 (https=) | 1973-07-18 | 1977-04-06 | ||
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| JP5171613B2 (ja) | 2006-03-01 | 2013-03-27 | 株式会社カネカ | ペプチドの製造方法 |
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| TW401421B (en) * | 1994-03-07 | 2000-08-11 | Syn Tech Chem & Pharm Co Ltd | A method of asymmeric synthezing of optically active peptides |
| JP2862167B2 (ja) * | 1995-03-02 | 1999-02-24 | 株式会社島津製作所 | 光学活性アミノ酸誘導体の回収方法 |
| CN101018803A (zh) * | 2004-07-16 | 2007-08-15 | 隆萨股份公司 | 肽合成法 |
| TW200626611A (en) * | 2004-09-20 | 2006-08-01 | Lonza Ag | Peptide cyclisation |
| JP5212371B2 (ja) | 2007-07-25 | 2013-06-19 | 味の素株式会社 | ペプチドの製造方法 |
| WO2012087307A1 (en) * | 2010-12-22 | 2012-06-28 | Empire Technology Development Llc | Economical, food-safe extraction of bisphenols |
| EP3266792B1 (en) * | 2015-03-04 | 2020-12-30 | Jitsubo Co., Ltd. | Peptide synthesis method |
| WO2018225851A1 (ja) * | 2017-06-09 | 2018-12-13 | 中外製薬株式会社 | Ｎ－置換アミノ酸を含むペプチドの合成方法 |
| EP3725796A4 (en) * | 2017-12-15 | 2021-09-15 | Chugai Seiyaku Kabushiki Kaisha | METHOD FOR MANUFACTURING PEPTIDE AND METHOD FOR PROCESSING BASES |
| EP3778621B1 (en) * | 2018-04-13 | 2023-08-23 | Jitsubo Co., Ltd. | Peptide synthesis method |
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2020
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| JPS5212371B2 (https=) | 1973-07-18 | 1977-04-06 | ||
| JP4142907B2 (ja) | 2001-07-19 | 2008-09-03 | ナームローゼ・フエンノートチヤツプ・オルガノン | ペプチドの高速溶液合成方法 |
| JP5171613B2 (ja) | 2006-03-01 | 2013-03-27 | 株式会社カネカ | ペプチドの製造方法 |
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| JP2025148420A (ja) | 2025-10-07 |
| CN114867734A (zh) | 2022-08-05 |
| EP4083051A4 (en) | 2024-01-17 |
| US20230056969A1 (en) | 2023-02-23 |
| CN114867734B (zh) | 2025-07-01 |
| JPWO2021132545A1 (https=) | 2021-07-01 |
| WO2021132545A1 (ja) | 2021-07-01 |
| TW202138382A (zh) | 2021-10-16 |
| JP7709920B2 (ja) | 2025-07-17 |
| EP4083051A1 (en) | 2022-11-02 |
| TWI873263B (zh) | 2025-02-21 |
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