KR20220007058A - 생물발광을 이용하는 분석물 검출을 위한 조성물 및 방법 - Google Patents

생물발광을 이용하는 분석물 검출을 위한 조성물 및 방법 Download PDF

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KR20220007058A
KR20220007058A KR1020217036614A KR20217036614A KR20220007058A KR 20220007058 A KR20220007058 A KR 20220007058A KR 1020217036614 A KR1020217036614 A KR 1020217036614A KR 20217036614 A KR20217036614 A KR 20217036614A KR 20220007058 A KR20220007058 A KR 20220007058A
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South Korea
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target analyte
seq
analyte binding
binding agent
sequence identity
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KR1020217036614A
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Korean (ko)
Inventor
토마스 커크랜드
멜라니 다트
즈양 쩡
토마스 스미스
키쓰 우드
토마스 매클레트
에밀리 죠스트
버지니아 킨케이드
후이 왕
원후이 저우
랜스 엔셀
메리 홀
로빈 허스트
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프로메가 코포레이션
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Publication of KR20220007058A publication Critical patent/KR20220007058A/ko
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/12—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
    • C12Y113/12007—Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/103—Nucleic acid detection characterized by the use of physical, structural and functional properties luminescence

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020217036614A 2019-04-10 2020-04-10 생물발광을 이용하는 분석물 검출을 위한 조성물 및 방법 Pending KR20220007058A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962832052P 2019-04-10 2019-04-10
US62/832,052 2019-04-10
PCT/US2020/027711 WO2020210658A1 (en) 2019-04-10 2020-04-10 Compositions and methods for analyte detection using bioluminescence

Publications (1)

Publication Number Publication Date
KR20220007058A true KR20220007058A (ko) 2022-01-18

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Family Applications (1)

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KR1020217036614A Pending KR20220007058A (ko) 2019-04-10 2020-04-10 생물발광을 이용하는 분석물 검출을 위한 조성물 및 방법

Country Status (11)

Country Link
US (2) US20200386748A1 (https=)
EP (1) EP3953374A4 (https=)
JP (2) JP7645812B2 (https=)
KR (1) KR20220007058A (https=)
CN (1) CN113891895A (https=)
AU (2) AU2020272037B2 (https=)
BR (1) BR112021020354A2 (https=)
CA (1) CA3135195A1 (https=)
IL (1) IL287261A (https=)
SG (1) SG11202110773RA (https=)
WO (1) WO2020210658A1 (https=)

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EP3395803A1 (en) 2017-04-28 2018-10-31 Institut Pasteur Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins
CA3158729A1 (en) * 2019-11-27 2021-06-03 Virginia Kincaid Multipartite luciferase peptides and polypeptides
US12606863B2 (en) 2021-05-13 2026-04-21 Promega Corporation Bioluminescent detection of DNA synthesis
WO2023028175A1 (en) * 2021-08-24 2023-03-02 Kaya17 Inc. System and method for detecting presence of a target bioparticle in a sample via a vertical flow assay
CN113786873B (zh) * 2021-08-31 2022-09-23 广西横县张一元饮品有限公司 一种用于食品安全检测的试管
EP4411377A4 (en) * 2021-09-29 2024-12-04 FUJIFILM Corporation Immunochromatography kit and testing device
CN114231401B (zh) * 2022-02-21 2022-05-03 北京芯迈微生物技术有限公司 一种核酸检测试剂盒及检测方法
WO2023200703A1 (en) * 2022-04-15 2023-10-19 Siemens Healthcare Diagnostics Inc. Creatinine lateral flow assay devices and methods of production and use thereof
GB2619059A (en) * 2022-05-26 2023-11-29 Univ Leeds Innovations Ltd Split reporter complex
EP4597108A4 (en) * 2022-09-26 2026-01-14 Fujifilm Corp IMMUNOCHROMATOGRAPHIC CARTRIDGE
TR2022019556A2 (tr) * 2022-12-16 2023-01-23 Duezce Ueniversitesi Rektoerluegue Strateji Gelistirme Daire Baskanligi Zehi̇rli̇ mantarlarin ve mantar zehi̇rlenmeleri̇ni̇n teşhi̇si̇ne olanak sağlayan halusi̇nojeni̇k etki̇ye sahi̇p psi̇losi̇bi̇n molekülü i̇çi̇n bi̇r kart testi̇
CN116218907B (zh) * 2023-02-20 2025-04-22 复旦大学附属中山医院 带有HiBiT新型报告基因的肠道病毒感染性克隆及其构建方法和应用
EP4695346A1 (en) * 2023-04-12 2026-02-18 Promega Corporation Poloxamer-stabilized reagents
WO2025024530A1 (en) * 2023-07-25 2025-01-30 The General Hospital Corporation Aldehyde binding optical imaging probes methods of use thereof
CN118033130B (zh) * 2024-01-19 2024-07-30 武汉科技大学 同时检测艾滋病、梅毒和丙肝的表面、微孔板、组件、方法及应用
CN118255903B (zh) * 2024-05-07 2025-03-11 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一种检测非洲猪瘟病毒抗体的融合抗原、制备方法及检测试剂盒
CN118344492B (zh) * 2024-05-07 2025-03-11 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一种纳米荧光素酶融合抗原在非洲猪瘟病毒抗体检测中的应用

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Publication number Publication date
IL287261A (en) 2021-12-01
EP3953374A4 (en) 2023-06-07
AU2020272037B2 (en) 2025-11-27
JP7645812B2 (ja) 2025-03-14
CN113891895A (zh) 2022-01-04
JP2025133108A (ja) 2025-09-10
US20200386748A1 (en) 2020-12-10
AU2020272037A1 (en) 2021-12-02
BR112021020354A2 (pt) 2021-12-14
CA3135195A1 (en) 2020-10-15
WO2020210658A1 (en) 2020-10-15
SG11202110773RA (en) 2021-10-28
AU2026201457A1 (en) 2026-03-19
JP2022526013A (ja) 2022-05-20
US20250264464A1 (en) 2025-08-21
EP3953374A1 (en) 2022-02-16

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