SG11202110773RA - Compositions and methods for analyte detection using bioluminescence - Google Patents

Compositions and methods for analyte detection using bioluminescence

Info

Publication number
SG11202110773RA
SG11202110773RA SG11202110773RA SG11202110773RA SG11202110773RA SG 11202110773R A SG11202110773R A SG 11202110773RA SG 11202110773R A SG11202110773R A SG 11202110773RA SG 11202110773R A SG11202110773R A SG 11202110773RA SG 11202110773R A SG11202110773R A SG 11202110773RA
Authority
SG
Singapore
Prior art keywords
target analyte
seq
analyte binding
binding agent
bioluminescent
Prior art date
Application number
SG11202110773RA
Other languages
English (en)
Inventor
Thomas Kirkland
Melanie Dart
Zhiyang Zeng
Thomas Smith
Keith Wood
Thomas Machleidt
Emily Jost
Virginia Kincaid
Hui Wang
Wenhui Zhou
Lance Encell
Mary Hall
Robin Hurst
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promega Corp filed Critical Promega Corp
Publication of SG11202110773RA publication Critical patent/SG11202110773RA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/12—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
    • C12Y113/12007—Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/103—Nucleic acid detection characterized by the use of physical, structural and functional properties luminescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG11202110773RA 2019-04-10 2020-04-10 Compositions and methods for analyte detection using bioluminescence SG11202110773RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962832052P 2019-04-10 2019-04-10
PCT/US2020/027711 WO2020210658A1 (en) 2019-04-10 2020-04-10 Compositions and methods for analyte detection using bioluminescence

Publications (1)

Publication Number Publication Date
SG11202110773RA true SG11202110773RA (en) 2021-10-28

Family

ID=72751365

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202110773RA SG11202110773RA (en) 2019-04-10 2020-04-10 Compositions and methods for analyte detection using bioluminescence

Country Status (11)

Country Link
US (2) US20200386748A1 (https=)
EP (1) EP3953374A4 (https=)
JP (2) JP7645812B2 (https=)
KR (1) KR20220007058A (https=)
CN (1) CN113891895A (https=)
AU (2) AU2020272037B2 (https=)
BR (1) BR112021020354A2 (https=)
CA (1) CA3135195A1 (https=)
IL (1) IL287261A (https=)
SG (1) SG11202110773RA (https=)
WO (1) WO2020210658A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3395803A1 (en) 2017-04-28 2018-10-31 Institut Pasteur Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins
CA3158729A1 (en) * 2019-11-27 2021-06-03 Virginia Kincaid Multipartite luciferase peptides and polypeptides
US12606863B2 (en) 2021-05-13 2026-04-21 Promega Corporation Bioluminescent detection of DNA synthesis
WO2023028175A1 (en) * 2021-08-24 2023-03-02 Kaya17 Inc. System and method for detecting presence of a target bioparticle in a sample via a vertical flow assay
CN113786873B (zh) * 2021-08-31 2022-09-23 广西横县张一元饮品有限公司 一种用于食品安全检测的试管
EP4411377A4 (en) * 2021-09-29 2024-12-04 FUJIFILM Corporation Immunochromatography kit and testing device
CN114231401B (zh) * 2022-02-21 2022-05-03 北京芯迈微生物技术有限公司 一种核酸检测试剂盒及检测方法
WO2023200703A1 (en) * 2022-04-15 2023-10-19 Siemens Healthcare Diagnostics Inc. Creatinine lateral flow assay devices and methods of production and use thereof
GB2619059A (en) * 2022-05-26 2023-11-29 Univ Leeds Innovations Ltd Split reporter complex
EP4597108A4 (en) * 2022-09-26 2026-01-14 Fujifilm Corp IMMUNOCHROMATOGRAPHIC CARTRIDGE
TR2022019556A2 (tr) * 2022-12-16 2023-01-23 Duezce Ueniversitesi Rektoerluegue Strateji Gelistirme Daire Baskanligi Zehi̇rli̇ mantarlarin ve mantar zehi̇rlenmeleri̇ni̇n teşhi̇si̇ne olanak sağlayan halusi̇nojeni̇k etki̇ye sahi̇p psi̇losi̇bi̇n molekülü i̇çi̇n bi̇r kart testi̇
CN116218907B (zh) * 2023-02-20 2025-04-22 复旦大学附属中山医院 带有HiBiT新型报告基因的肠道病毒感染性克隆及其构建方法和应用
EP4695346A1 (en) * 2023-04-12 2026-02-18 Promega Corporation Poloxamer-stabilized reagents
WO2025024530A1 (en) * 2023-07-25 2025-01-30 The General Hospital Corporation Aldehyde binding optical imaging probes methods of use thereof
CN118033130B (zh) * 2024-01-19 2024-07-30 武汉科技大学 同时检测艾滋病、梅毒和丙肝的表面、微孔板、组件、方法及应用
CN118255903B (zh) * 2024-05-07 2025-03-11 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一种检测非洲猪瘟病毒抗体的融合抗原、制备方法及检测试剂盒
CN118344492B (zh) * 2024-05-07 2025-03-11 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一种纳米荧光素酶融合抗原在非洲猪瘟病毒抗体检测中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3423290A (en) * 1966-08-03 1969-01-21 Nasa Lyophilized reaction mixtures
US6045254A (en) * 1996-12-26 2000-04-04 M.L.I.S. Projects Ltd. Container having two or more compartments
US7118878B1 (en) * 2000-06-09 2006-10-10 Promega Corporation Method for increasing luminescence assay sensitivity
JP4485470B2 (ja) * 2002-12-23 2010-06-23 プロメガ コーポレイション ルシフェラーゼ酵素活性を保護するための方法及びキット
US7829347B2 (en) * 2005-08-31 2010-11-09 Kimberly-Clark Worldwide, Inc. Diagnostic test kits with improved detection accuracy
AU2007217765A1 (en) * 2006-02-21 2007-08-30 Nanogen, Inc. Methods and compositions for analyte detection
US10067149B2 (en) * 2012-12-12 2018-09-04 Promega Corporation Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer
KR102292431B1 (ko) * 2012-12-12 2021-08-20 프로메가 코포레이션 세포내 생물발광 공명 에너지 전이를 이용하여 생물활성제에 의한 세포 표적 결합의 인식
ES2926463T3 (es) * 2013-03-15 2022-10-26 Promega Corp Activación de la bioluminiscencia mediante complementación estructural
JP6814132B2 (ja) * 2014-09-12 2021-01-13 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 内部タンパク質タグ
WO2016127100A1 (en) * 2015-02-05 2016-08-11 Promega Corporation Luciferase-based thermal shift assays
WO2017143323A1 (en) * 2016-02-19 2017-08-24 Insight Instruments, Inc. Assay systems for point of care detection of ocular analytes
WO2017189751A1 (en) * 2016-04-26 2017-11-02 The University Of Utah Research Foundation Target-binding activated split reporter systems for analyte detection and related components and methods
US11327072B2 (en) * 2017-02-09 2022-05-10 Promega Corporation Analyte detection immunoassay
JP6990369B2 (ja) * 2017-05-19 2022-02-03 国立大学法人 熊本大学 遺伝性腎疾患アルポート症候群治療薬に係る評価系

Also Published As

Publication number Publication date
IL287261A (en) 2021-12-01
EP3953374A4 (en) 2023-06-07
AU2020272037B2 (en) 2025-11-27
JP7645812B2 (ja) 2025-03-14
CN113891895A (zh) 2022-01-04
JP2025133108A (ja) 2025-09-10
US20200386748A1 (en) 2020-12-10
AU2020272037A1 (en) 2021-12-02
BR112021020354A2 (pt) 2021-12-14
CA3135195A1 (en) 2020-10-15
WO2020210658A1 (en) 2020-10-15
AU2026201457A1 (en) 2026-03-19
KR20220007058A (ko) 2022-01-18
JP2022526013A (ja) 2022-05-20
US20250264464A1 (en) 2025-08-21
EP3953374A1 (en) 2022-02-16

Similar Documents

Publication Publication Date Title
AU2020272037B2 (en) Compositions and methods for analyte detection using bioluminescence
JP4968611B2 (ja) 免疫抑制剤の改善された測定法
WO2015039423A1 (zh) 生物标记物的保存液、试剂和方法
US7141436B2 (en) Immunoassay and reagents and kits for performing the same
WO2011057347A1 (en) Analyte detection
WO2007111847A2 (en) Use of additives for the reduction of non-specific binding in assays
JP2011241206A (ja) 標識抗体の安定化方法
JP7837518B2 (ja) 蛍光偏光免疫分析法
FR2917173A1 (fr) Procede multiplexe de detection d'une infection
CN104169710A (zh) 用于时间分辨荧光免疫测定检验的方法和装置
Mechaly et al. A novel homogeneous immunoassay for anthrax detection based on the AlphaLISA method: detection of B. anthracis spores and protective antigen (PA) in complex samples
BR112014020513B1 (pt) Métodos e sistemas para amplificação de sinal de bioensaios
US20210382075A1 (en) Saturation binding ratiometric assay
JP2008268043A (ja) 検査デバイスの検出部の形成方法及びラテラルフロー免疫測定用検査デバイス
EP3564673B1 (en) L-fabp immunoassay method and assay reagent used in said method
JP2013125005A (ja) Ｃｋ−ｍｂ測定用ラテックス凝集免疫試薬及び測定方法
JP4486059B2 (ja) 免疫測定用ラテックス組成物
Sapsford et al. Detection of HIV-1 specific monoclonal antibodies using enhancement of dye-labeled antigenic peptides
US20250277787A1 (en) Enhanced lateral flow assays and devices for detecting analytes in blood samples
KR20240051109A (ko) 검정 신호 증폭을 위한 방법, 조성물 및 키트
Nazem Viral Nanoparticles as Lateral Flow Assay Reporters: Analysis of Capture Kinetics, Stabilization, and Detection In Blood
HK1134542A (en) Homogeneous double receptor agglutination assay for immunosuppressant drugs
JP2008196997A (ja) 核酸の定量方法
CN101490559A (zh) 免疫抑制药物的同质双重受体凝集测定法