KR20200030126A - Ssao의 치환된 3-할로알릴아민 억제제들 및 그 용도들 - Google Patents

Ssao의 치환된 3-할로알릴아민 억제제들 및 그 용도들 Download PDF

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KR20200030126A
KR20200030126A KR1020207007076A KR20207007076A KR20200030126A KR 20200030126 A KR20200030126 A KR 20200030126A KR 1020207007076 A KR1020207007076 A KR 1020207007076A KR 20207007076 A KR20207007076 A KR 20207007076A KR 20200030126 A KR20200030126 A KR 20200030126A
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compound
disease
compounds
ssao
vap
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Korean (ko)
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맨달 데오드할
알리손 도로시 핀들레이
조나단 스튜어트 풋
울프강 자로리멕
이안 알렉산더 맥도날드
앨런 로버트손
크레이그 이반 터너
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베링거 인겔하임 인터내셔날 게엠베하
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    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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  • Rheumatology (AREA)
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  • Obesity (AREA)
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  • Dermatology (AREA)
  • Communicable Diseases (AREA)
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KR1020207007076A 2012-05-02 2013-04-05 Ssao의 치환된 3-할로알릴아민 억제제들 및 그 용도들 Ceased KR20200030126A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261641814P 2012-05-02 2012-05-02
US61/641,814 2012-05-02
PCT/AU2013/000356 WO2013163675A1 (en) 2012-05-02 2013-04-05 Substituted 3-haloallylamine inhibitors of ssao and uses thereof

Related Parent Applications (1)

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KR1020147032073A Division KR102089935B1 (ko) 2012-05-02 2013-04-05 Ssao의 치환된 3-할로알릴아민 억제제들 및 이들의 용도들

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KR20200030126A true KR20200030126A (ko) 2020-03-19

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KR1020207007076A Ceased KR20200030126A (ko) 2012-05-02 2013-04-05 Ssao의 치환된 3-할로알릴아민 억제제들 및 그 용도들
KR1020147032073A Active KR102089935B1 (ko) 2012-05-02 2013-04-05 Ssao의 치환된 3-할로알릴아민 억제제들 및 이들의 용도들

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KR1020147032073A Active KR102089935B1 (ko) 2012-05-02 2013-04-05 Ssao의 치환된 3-할로알릴아민 억제제들 및 이들의 용도들

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US (4) US9302986B2 (enExample)
EP (2) EP3438087A1 (enExample)
JP (3) JP6182595B2 (enExample)
KR (2) KR20200030126A (enExample)
CN (2) CN104520268B (enExample)
AU (2) AU2013255103B2 (enExample)
BR (1) BR112014027406B1 (enExample)
CA (2) CA2871793C (enExample)
CY (1) CY1120334T1 (enExample)
DK (1) DK2844637T5 (enExample)
ES (1) ES2668300T3 (enExample)
HR (1) HRP20180953T1 (enExample)
HU (1) HUE038437T2 (enExample)
LT (1) LT2844637T (enExample)
ME (1) ME03063B (enExample)
MX (2) MX360634B (enExample)
NO (1) NO2842608T3 (enExample)
PL (1) PL2844637T3 (enExample)
PT (1) PT2844637T (enExample)
RS (1) RS57086B1 (enExample)
SG (2) SG11201406948PA (enExample)
SI (1) SI2844637T1 (enExample)
TR (1) TR201807453T4 (enExample)
WO (1) WO2013163675A1 (enExample)

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CN104520268B (zh) * 2012-05-02 2017-05-24 勃林格殷格翰国际有限公司 Ssao的取代的3‑卤代烯丙基胺抑制剂及其用途
GB201304526D0 (en) 2013-03-13 2013-04-24 Proximagen Ltd New compounds
WO2015189534A1 (en) 2014-06-12 2015-12-17 Proximagen Limited Vap-1 inhibitors for treating muscular dystrophy
JP2018076236A (ja) * 2015-06-05 2018-05-17 株式会社アールテック・ウエノ がんを処置するための医薬組成物
JP2019502672A (ja) 2015-12-07 2019-01-31 ベネボレンタイ ケンブリッジ リミティド 疼痛の治療のためのｖａｐ−１阻害剤
CA3013850C (en) * 2016-02-12 2024-01-30 Pharmaxis Ltd. Haloallylamine indole and azaindole derivative inhibitors of lysyl oxidases and uses thereof
WO2018027892A1 (en) 2016-08-12 2018-02-15 Eli Lilly And Company Amino pyrimidine ssao inhibitors
US20210212968A1 (en) * 2016-10-19 2021-07-15 Boehringer Ingelheim International Gmbh Combinations comprising an ssao/vap-1 inhibitor and a sglt2 inhibitor, uses thereof
EP3824906A1 (en) 2016-12-21 2021-05-26 Amgen Inc. Anti-tnf alpha antibody formulations
CN108341752B (zh) * 2017-01-21 2022-12-23 广东东阳光药业有限公司 抑制ssao/vap-1的胺类化合物及其在医药上的应用
WO2018148856A1 (en) * 2017-02-14 2018-08-23 Eli Lilly And Company Diazaspirodecanyl-pyrimidine compounds useful as ssao inhibitors
HUE064755T2 (hu) 2017-03-01 2024-04-28 Boehringer Ingelheim Int Alfa-halo-akrilsav-származékok átmenetifém-katalizált protodekarboxilezõdése
JP2020508996A (ja) * 2017-03-02 2020-03-26 ファーマクシス リミテッド リシルオキシダーゼのハロアリルアミンピラゾール誘導体阻害剤およびその使用
US20200087248A1 (en) * 2017-04-28 2020-03-19 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Fluoroallylamine Derivative And Use Thereof
JP2020521795A (ja) * 2017-05-31 2020-07-27 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング （Ｅ）−４−（２−（アミノメチル）−３−フルオロアリルオキシ）−Ｎ−ｔｅｒｔ−ブチルベンズアミドを含む医薬組成物および医薬剤形、それらの調製方法、治療方法およびそれらの使用
GB201709136D0 (en) * 2017-06-08 2017-07-26 Proximagen Ltd New therapeutic uses of enzyme inhibitors
JP6861858B2 (ja) * 2017-06-20 2021-04-21 山東丹紅制薬有限公司Ｓｈａｎｄｏｎｇ Ｄａｎｈｏｎｇ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． Ｓｓａｏ阻害剤
CN109251166B (zh) * 2017-07-13 2021-11-05 广东东阳光药业有限公司 抑制ssao/vap-1的胺类化合物及其在医药上的应用
WO2019024924A1 (zh) * 2017-08-04 2019-02-07 广东东阳光药业有限公司 抑制ssao/vap-1的胺类化合物及其在医药上的应用
CN109810041B (zh) 2017-11-21 2023-08-15 药捷安康(南京)科技股份有限公司 卤代烯丙基胺类ssao/vap-1抑制剂及其应用
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