KR20190128634A - 다중 트랜스진 재조합 아데노바이러스 - Google Patents
다중 트랜스진 재조합 아데노바이러스 Download PDFInfo
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- KR20190128634A KR20190128634A KR1020197025498A KR20197025498A KR20190128634A KR 20190128634 A KR20190128634 A KR 20190128634A KR 1020197025498 A KR1020197025498 A KR 1020197025498A KR 20197025498 A KR20197025498 A KR 20197025498A KR 20190128634 A KR20190128634 A KR 20190128634A
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- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
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| US201762452342P | 2017-01-30 | 2017-01-30 | |
| US62/452,342 | 2017-01-30 | ||
| US201762520945P | 2017-06-16 | 2017-06-16 | |
| US62/520,945 | 2017-06-16 | ||
| PCT/US2018/016032 WO2018140973A1 (en) | 2017-01-30 | 2018-01-30 | Multiple transgene recombinant adenovirus |
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| KR20190128634A true KR20190128634A (ko) | 2019-11-18 |
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| KR102089121B1 (ko) | 2013-03-14 | 2020-03-13 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양살상형 아데노바이러스 조성물 |
| KR20180112024A (ko) | 2016-02-23 | 2018-10-11 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 바이러스 동역학에 미치는 영향 최소화를 위한 치료용 아데노바이러스의 외인성 유전자 발현 |
| CA3013637A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| AU2017375633C1 (en) | 2016-12-12 | 2023-04-27 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| EA201990822A1 (ru) | 2017-04-12 | 2020-01-09 | Эписентарикс, Инк. | Иммуномодулирующие слитые белки |
| JP7245175B2 (ja) * | 2017-05-24 | 2023-03-23 | エピセントアールエックス，インコーポレイテッド | 抗脈管形成アデノウイルス |
| AU2019251356B2 (en) | 2018-04-09 | 2025-06-12 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions with enhanced replication properties |
| US20250177509A1 (en) * | 2020-07-06 | 2025-06-05 | Jiaxing Anyu Biotechnology Co., Ltd | Recombinant adenovirus vaccine for african swine fever and method for constructing same |
| WO2022246646A1 (zh) * | 2021-05-25 | 2022-12-01 | 江苏万戎生物医药科技有限公司 | 一款多重机制协同和增效免疫治疗的嵌合型广谱溶瘤腺病毒及其在肿瘤治疗中的应用 |
| CN113249342B (zh) * | 2021-05-25 | 2023-12-01 | 江苏万戎生物医药科技有限公司 | 一款多重机制协同和增效免疫治疗的嵌合型广谱溶瘤腺病毒及其在肿瘤治疗中的应用 |
| EP4554559A1 (en) | 2022-07-13 | 2025-05-21 | EpicentRx, Inc. | Adenoviral vectors encapsulated in cationic liposomes, and preparation and use thereof |
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| KR100896483B1 (ko) * | 2007-07-13 | 2009-05-08 | 연세대학교 산학협력단 | Ｉｌ-12 및 4-1ｂｂｌ을 발현하는 종양 선택적 살상 재조합아데노바이러스 및 수지상 세포를 유효성분으로 포함하는항종양용 약제학적 조성물 |
| DK3029144T3 (da) * | 2009-03-02 | 2019-10-21 | Univ California | Tumorselektive adenovirus e1a- og e1b-mutanter |
| RU2612788C2 (ru) * | 2010-03-23 | 2017-03-13 | Интрексон Корпорейшн | Векторы, условно экспрессирующие терапевтические белки, клетки-хозяева, содержащие указанные векторы, и их применение |
| CA2812093A1 (en) * | 2010-09-24 | 2012-03-29 | Oncos Therapeutics Oy | Oncolytic adenoviral vectors coding for monoclonal anti - ctla - 4 antibodies |
| AU2013214776B2 (en) * | 2012-02-02 | 2017-11-09 | Board Of Regents, The University Of Texas System | Adenoviruses expressing heterologous tumor-associated antigens |
| CA2909432C (en) * | 2013-04-18 | 2025-11-18 | Tilt Biotherapeutics Oy | Enhanced adoptive cell therapy |
| CN103614416B (zh) * | 2013-09-30 | 2016-09-07 | 中国人民解放军第二军医大学东方肝胆外科医院 | 一种携带人穿膜肽p53与GM-CSF基因的重组溶瘤腺病毒及其用途 |
| JP6764859B2 (ja) * | 2014-09-24 | 2020-10-07 | ソーク インスティテュート フォー バイオロジカル スタディーズ | 腫瘍崩壊性腫瘍ウイルスおよび使用の方法 |
| US10232053B2 (en) * | 2016-12-30 | 2019-03-19 | Trieza Therapeutics, Inc. | Immunomodulatory oncolytic adenoviral vectors, and methods of production and use thereof for treatment of cancer |
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| IL268291A (en) | 2019-09-26 |
| BR112019015600A2 (pt) | 2020-03-17 |
| CA3052090A1 (en) | 2018-08-02 |
| SG11201906973TA (en) | 2019-08-27 |
| US20190352616A1 (en) | 2019-11-21 |
| EP3574090A4 (en) | 2021-01-06 |
| JP2020505049A (ja) | 2020-02-20 |
| MX2019008921A (es) | 2019-11-08 |
| WO2018140973A1 (en) | 2018-08-02 |
| CN110741080A (zh) | 2020-01-31 |
| AU2018213417A1 (en) | 2019-08-15 |
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