KR20190128254A - 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 ａｌｋ１ 길항제 기재의 방법 및 조성물 - Google Patents
혈관신생 및 혈관주위세포 적용범위의 조정을 위한 ａｌｋ１ 길항제 기재의 방법 및 조성물 Download PDFInfo
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US5016808P | 2008-05-02 | 2008-05-02 | |
| US61/050,168 | 2008-05-02 | ||
| US14413109P | 2009-01-12 | 2009-01-12 | |
| US61/144,131 | 2009-01-12 | ||
| PCT/US2009/002699 WO2009134428A2 (en) | 2008-05-02 | 2009-05-01 | Methods and compositions for modulating angiogenesis and pericyte composition |
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| KR20190128254A true KR20190128254A (ko) | 2019-11-15 |
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| KR1020207018412A Withdrawn KR20200079567A (ko) | 2008-05-02 | 2009-05-01 | 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 ａｌｋ１ 길항제 기재의 방법 및 조성물 |
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| KR1020217003129A Withdrawn KR20210014224A (ko) | 2008-05-02 | 2009-05-01 | 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 ａｌｋ１ 길항제 기재의 방법 및 조성물 |
| KR1020107027046A Ceased KR20110031908A (ko) | 2008-05-02 | 2009-05-01 | 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 ａｌｋ１ 길항제 기재의 방법 및 조성물 |
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| KR1020177002063A Ceased KR20170012595A (ko) | 2008-05-02 | 2009-05-01 | 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 ａｌｋ１ 길항제 기재의 방법 및 조성물 |
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| KR1020217003129A Withdrawn KR20210014224A (ko) | 2008-05-02 | 2009-05-01 | 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 ａｌｋ１ 길항제 기재의 방법 및 조성물 |
| KR1020107027046A Ceased KR20110031908A (ko) | 2008-05-02 | 2009-05-01 | 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 ａｌｋ１ 길항제 기재의 방법 및 조성물 |
| KR1020187006926A Ceased KR20180029111A (ko) | 2008-05-02 | 2009-05-01 | 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 ａｌｋ１ 길항제 기재의 방법 및 조성물 |
| KR1020177002063A Ceased KR20170012595A (ko) | 2008-05-02 | 2009-05-01 | 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 ａｌｋ１ 길항제 기재의 방법 및 조성물 |
| KR1020197008836A Withdrawn KR20190037355A (ko) | 2008-05-02 | 2009-05-01 | 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 ａｌｋ１ 길항제 기재의 방법 및 조성물 |
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Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8642031B2 (en) | 2006-11-02 | 2014-02-04 | Acceleron Pharma, Inc. | Antagonists of BMP9, BMP10, ALK1 and other ALK1 ligands, and uses thereof |
| US10059756B2 (en) | 2006-11-02 | 2018-08-28 | Acceleron Pharma Inc. | Compositions comprising ALK1-ECD protein |
| ES2612755T3 (es) | 2006-11-02 | 2017-05-18 | Acceleron Pharma, Inc. | Antagonistas de receptor y ligando de ALK1 y usos de los mismos |
| CA2703099A1 (en) | 2007-11-09 | 2009-05-14 | Genentech, Inc. | Activin receptor-like kinase-i compositions and methods of use |
| AU2009241755B2 (en) * | 2008-05-02 | 2015-10-01 | Acceleron Pharma Inc. | Methods and compositions based on ALK1 antagonists for modulating angiogenesis and pericyte coverage |
| CA2724525A1 (en) * | 2008-05-15 | 2009-11-19 | Acceleron Pharma, Inc. | Antagonists of bmp9, bmp10, alk1 and other alk1 ligands, and uses thereof |
| CN104321070A (zh) * | 2012-02-02 | 2015-01-28 | 艾科赛扬制药股份有限公司 | Alk1拮抗剂及其在治疗肾细胞癌中的用途 |
| US9809636B2 (en) | 2012-04-06 | 2017-11-07 | Acceleron Pharma Inc. | Methods for increasing red blood cell levels comprising administering BMP9 |
| HK1225742A1 (zh) * | 2013-08-22 | 2017-09-15 | Acceleron Pharma, Inc. | TGF-β受体II型变体及其用途 |
| JP2016036322A (ja) * | 2014-08-11 | 2016-03-22 | 日本化薬株式会社 | 血管新生因子と結合するキメラタンパク質 |
| BR112017021510A2 (pt) * | 2015-04-06 | 2018-07-03 | Acceleron Pharma Inc | heteromultímeros do receptor tipo i e tipo ii da superfamília tgf-beta e sua utilização |
| EP3280727B1 (en) * | 2015-04-06 | 2021-02-17 | Acceleron Pharma Inc. | Single-arm type i and type ii receptor fusion proteins and uses thereof |
| CN110452295B (zh) * | 2015-11-10 | 2022-10-11 | 孙嘉琳 | 抗肿瘤蛋白内皮抑素的衍生物 |
| RS62011B1 (sr) | 2016-07-15 | 2021-07-30 | Acceleron Pharma Inc | Kompozicije koje sadrže polipeptide actriia za upotrebu u lečenju plućne hipertenzije |
| CA3039525A1 (en) | 2016-10-05 | 2018-04-12 | Acceleron Pharma Inc. | Variant actriib proteins and uses thereof |
| RU2020117439A (ru) * | 2017-11-02 | 2021-12-02 | Байер Акциенгезельшафт | БИСПЕЦИФИЧЕСКИЕ АНТИТЕЛА, СВЯЗЫВАЮЩИЕ ALK-1 и BMPR-2 |
| CN114028541A (zh) * | 2021-05-21 | 2022-02-11 | 中山大学 | Gdf2在制备改善肿瘤异常血管的药物中的用途 |
| WO2024153115A1 (zh) * | 2023-01-18 | 2024-07-25 | 开拓药业(广东)有限公司 | 抗alk-1抗体及其用途 |
| US20250002588A1 (en) | 2023-04-07 | 2025-01-02 | Diagonal Therapeutics Inc. | Bispecific agonistic antibodies to activin a receptor like type 1 (alk1) |
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| CA2724525A1 (en) * | 2008-05-15 | 2009-11-19 | Acceleron Pharma, Inc. | Antagonists of bmp9, bmp10, alk1 and other alk1 ligands, and uses thereof |
-
2009
- 2009-05-01 AU AU2009241755A patent/AU2009241755B2/en not_active Ceased
- 2009-05-01 CN CN201610297436.0A patent/CN105963695A/zh active Pending
- 2009-05-01 TW TW104119480A patent/TW201609138A/zh unknown
- 2009-05-01 TW TW098114652A patent/TWI586364B/zh not_active IP Right Cessation
- 2009-05-01 EP EP09739231A patent/EP2283040A2/en not_active Withdrawn
- 2009-05-01 KR KR1020197032900A patent/KR20190128254A/ko not_active Withdrawn
- 2009-05-01 KR KR1020207018412A patent/KR20200079567A/ko not_active Withdrawn
- 2009-05-01 JP JP2011507463A patent/JP5719766B2/ja not_active Expired - Fee Related
- 2009-05-01 KR KR1020217028926A patent/KR20210113446A/ko not_active Ceased
- 2009-05-01 WO PCT/US2009/002699 patent/WO2009134428A2/en not_active Ceased
- 2009-05-01 MX MX2017011333A patent/MX391905B/es unknown
- 2009-05-01 CA CA2723449A patent/CA2723449C/en active Active
- 2009-05-01 KR KR1020217003129A patent/KR20210014224A/ko not_active Withdrawn
- 2009-05-01 KR KR1020107027046A patent/KR20110031908A/ko not_active Ceased
- 2009-05-01 CN CN200980125712.3A patent/CN102099374B/zh not_active Expired - Fee Related
- 2009-05-01 MX MX2010011998A patent/MX2010011998A/es active IP Right Grant
- 2009-05-01 US US12/434,598 patent/US8158584B2/en active Active
- 2009-05-01 TW TW106106131A patent/TWI672151B/zh not_active IP Right Cessation
- 2009-05-01 KR KR1020187006926A patent/KR20180029111A/ko not_active Ceased
- 2009-05-01 KR KR1020177002063A patent/KR20170012595A/ko not_active Ceased
- 2009-05-01 BR BRPI0911853A patent/BRPI0911853A8/pt not_active IP Right Cessation
- 2009-05-01 KR KR1020197008836A patent/KR20190037355A/ko not_active Withdrawn
- 2009-05-01 EP EP18154273.9A patent/EP3398966A1/en active Pending
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2012
- 2012-04-13 US US13/447,077 patent/US20130039910A1/en not_active Abandoned
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2014
- 2014-11-25 JP JP2014237666A patent/JP6194302B2/ja not_active Expired - Fee Related
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2016
- 2016-01-04 AU AU2016200018A patent/AU2016200018A1/en not_active Abandoned
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2017
- 2017-02-28 JP JP2017037131A patent/JP2017101068A/ja not_active Withdrawn
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2018
- 2018-01-11 AU AU2018200237A patent/AU2018200237B2/en not_active Ceased
- 2018-02-13 US US15/895,894 patent/US20180179293A1/en not_active Abandoned
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2019
- 2019-09-18 AU AU2019232838A patent/AU2019232838B2/en not_active Ceased
- 2019-09-20 JP JP2019171838A patent/JP2019210298A/ja not_active Withdrawn
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2021
- 2021-01-04 US US17/140,398 patent/US20210388104A1/en not_active Abandoned
- 2021-09-03 JP JP2021144016A patent/JP2021183652A/ja active Pending
- 2021-12-13 AU AU2021286240A patent/AU2021286240A1/en not_active Abandoned
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