KR20190011836A - 돌연변이 인자 ｈ 결합 단백질을 포함하는 백신 조성물 - Google Patents
돌연변이 인자 ｈ 결합 단백질을 포함하는 백신 조성물 Download PDFInfo
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- KR20190011836A KR20190011836A KR1020197002691A KR20197002691A KR20190011836A KR 20190011836 A KR20190011836 A KR 20190011836A KR 1020197002691 A KR1020197002691 A KR 1020197002691A KR 20197002691 A KR20197002691 A KR 20197002691A KR 20190011836 A KR20190011836 A KR 20190011836A
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- Prior art keywords
- factor
- binding protein
- binding
- meningitidis
- composition
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| CN100379757C (zh) | 1998-05-01 | 2008-04-09 | 希龙公司 | 脑膜炎奈瑟球菌抗原和组合物 |
| BR0010721A (pt) | 1999-05-19 | 2002-06-11 | Chiron Spa | Composições de neisserias combinadas |
| PT2275551E (pt) | 1999-10-29 | 2015-06-29 | Novartis Vaccines & Diagnostic | Péptidos antigénicos de neisseria |
| ES2281409T3 (es) | 2000-02-28 | 2007-10-01 | Novartis Vaccines And Diagnostics S.R.L. | Expresion heterologa de proteinas de neisseria. |
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| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| DK2353608T3 (da) | 2002-10-11 | 2020-02-10 | Novartis Vaccines And Diagnostics S R L | Polypeptid-vacciner til bred beskyttelse mod hypervirulente meningokok-linjer |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| WO2009104097A2 (en) | 2008-02-21 | 2009-08-27 | Novartis Ag | Meningococcal fhbp polypeptides |
| AU2009223613B2 (en) | 2008-03-10 | 2014-09-25 | Children's Hospital & Research Center At Oakland | Chimeric factor H binding proteins (fHBP) containing a heterologous B domain and methods of use |
| CA2756522C (en) | 2009-03-24 | 2018-06-26 | Novartis Ag | Adjuvanting meningococcal factor h binding protein |
| WO2010127172A2 (en) | 2009-04-30 | 2010-11-04 | Children's Hospital & Research Center At Oakland | Chimeric factor h binding proteins (fhbp) and methods of use |
| US20130022633A1 (en) * | 2009-10-27 | 2013-01-24 | University Of Florence | MENINGOCOCCAL fHBP POLYPEPTIDES |
| JP2013521326A (ja) * | 2010-03-10 | 2013-06-10 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 免疫原性組成物 |
| BR122021020829B8 (pt) * | 2010-03-30 | 2022-12-27 | Children´S Hospital & Res Center At Oakland | Proteína de ligação ao fator h de ocorrência não natural (fhbp), composição, e célula hospedeira de neisseria meningitidis geneticamente modificada |
| US10478483B2 (en) | 2010-06-25 | 2019-11-19 | Glaxosmithkline Biologicals Sa | Combinations of meningococcal factor H binding proteins |
| BR112014019166A2 (pt) | 2012-02-02 | 2017-07-04 | Novartis Ag | promotores para expressão aumentada de proteína em meningococos |
| WO2013186753A1 (en) | 2012-06-14 | 2013-12-19 | Novartis Ag | Vaccines for serogroup x meningococcus |
| HK1205138A1 (en) | 2012-07-27 | 2015-12-11 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia |
| US20160030544A1 (en) * | 2013-03-14 | 2016-02-04 | Isis Innovation Limited | Immunogenic composition to neisseria |
| BR112016002150A2 (pt) | 2013-08-02 | 2017-09-12 | Children´S Hospital & Res Center At Oakland | proteínas de ligação de fator h de ocorrência natural (fhbp) e métodos de uso das mesmas |
| AU2015222121B2 (en) | 2014-02-28 | 2018-01-18 | Glaxosmithkline Biologicals Sa | Modified meningococcal fHbp polypeptides |
| KR102761870B1 (ko) | 2014-07-23 | 2025-02-05 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 인자 h 결합 단백질 변이체 및 이의 사용 방법 |
| AU2015304079B2 (en) * | 2014-08-20 | 2021-05-13 | Stichting Sanquin Bloedvoorziening | Factor H potentiating antibodies and uses thereof |
| GB201614687D0 (en) * | 2016-08-31 | 2016-10-12 | Univ Oxford Innovation Ltd | fHbp scaffold |
| EP3607967A1 (en) | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| MX2021007539A (es) | 2018-12-21 | 2021-09-21 | Univ Griffith | Composiciones, metodos y usos para provocar una respuesta inmune. |
| CA3147314A1 (en) * | 2019-07-08 | 2021-01-14 | J. McLeod GRIFFISS | Methods of making and using lipooligosaccharide compositions and vaccines |
| BR112022000739A2 (pt) | 2019-07-17 | 2022-04-12 | Gemini Therapeutics Sub Inc | Anticorpos de potencialização de fator h e usos dos mesmos |
| CA3211240A1 (en) | 2021-02-19 | 2022-08-25 | Sanofi Pasteur Inc. | Meningococcal b recombinant vaccine |
| TW202423477A (zh) | 2022-08-03 | 2024-06-16 | 美商賽諾菲巴斯德公司 | 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物 |
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| US4786592A (en) * | 1986-06-18 | 1988-11-22 | Scripps Clinic And Research Foundation | Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin |
| US5476784A (en) * | 1993-04-06 | 1995-12-19 | Rice; Peter A. | Gonococcal anti-idiotypic antibodies and methods and compositions using them |
| GB0220194D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| KR20060019515A (ko) * | 2003-04-16 | 2006-03-03 | 와이어쓰 홀딩스 코포레이션 | 수막구균 질환의 예방 및 치료용 신규 면역원성 조성물 |
| SI2682126T1 (sl) * | 2005-01-27 | 2017-03-31 | Children's Hospital & Research Center At Oakland | Cepiva na osnovi veziklov, osnovanih na GNA1870, za širokospektralno zaščito proti boleznim, povzročenim z Neisserio meningitidisom |
| GB0524066D0 (en) * | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| CA2656474A1 (en) * | 2006-06-29 | 2008-01-03 | Novartis Ag | Polypeptides from neisseria meningitidis |
| CN102596240B (zh) * | 2009-08-27 | 2015-02-04 | 诺华股份有限公司 | 包括脑膜炎球菌fHBP序列的杂交多肽 |
| BR122021020829B8 (pt) * | 2010-03-30 | 2022-12-27 | Children´S Hospital & Res Center At Oakland | Proteína de ligação ao fator h de ocorrência não natural (fhbp), composição, e célula hospedeira de neisseria meningitidis geneticamente modificada |
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