RU2559528C2 - КОМПОЗИЦИИ ВАКЦИН ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ ИНФЕКЦИИ ИЛИ ЗАБОЛЕВАНИЯ, ВЫЗЫВАЕМЫХ Neisseria meningitides И/ИЛИ Neisseria gonorrhoeae, СОДЕРЖАЩИЕ МУТИРОВАННЫЙ БЕЛОК, СВЯЗЫВАЮЩИЙ ФАКТОР Н - Google Patents
КОМПОЗИЦИИ ВАКЦИН ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ ИНФЕКЦИИ ИЛИ ЗАБОЛЕВАНИЯ, ВЫЗЫВАЕМЫХ Neisseria meningitides И/ИЛИ Neisseria gonorrhoeae, СОДЕРЖАЩИЕ МУТИРОВАННЫЙ БЕЛОК, СВЯЗЫВАЮЩИЙ ФАКТОР Н Download PDFInfo
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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| PCT/GB2009/051439 WO2010046715A1 (en) | 2008-10-25 | 2009-10-26 | Vaccine compositions comprising a mutated factor h binding protein |
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| MX343752B (es) | 1998-05-01 | 2016-11-22 | Novartis Vaccines & Diagnostics Inc | Antigenos de neisseria meningitidis y composiciones que los contienen. |
| EP1179072A2 (en) | 1999-05-19 | 2002-02-13 | Chiron S.P.A. | Combination neisserial compositions |
| PT2275551E (pt) | 1999-10-29 | 2015-06-29 | Novartis Vaccines & Diagnostic | Péptidos antigénicos de neisseria |
| PT2270030E (pt) | 2000-02-28 | 2012-07-24 | Novartis Vaccines & Diagnostic | Expressão heteróloga de proteínas de neisseria |
| GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| EP2351579B1 (en) | 2002-10-11 | 2016-09-21 | Novartis Vaccines and Diagnostics S.r.l. | Polypeptide vaccines for broad protection against hypervirulent meningococcal lineages |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| AU2009215364B2 (en) | 2008-02-21 | 2014-09-18 | Glaxosmithkline Biologicals S.A. | Meningococcal fHBP polypeptides |
| AU2009223613B2 (en) | 2008-03-10 | 2014-09-25 | Children's Hospital & Research Center At Oakland | Chimeric factor H binding proteins (fHBP) containing a heterologous B domain and methods of use |
| CN104548082A (zh) | 2009-03-24 | 2015-04-29 | 诺华股份有限公司 | 为脑膜炎球菌因子h结合蛋白添加佐剂 |
| US9266942B2 (en) | 2009-04-30 | 2016-02-23 | Children's Hospital & Research Center Oakland | Chimeric factor H binding proteins (fHbp) and methods of use |
| CA2779816A1 (en) | 2009-10-27 | 2011-05-05 | Novartis Ag | Modified meningococcal fhbp polypeptides |
| EP2544714A1 (en) * | 2010-03-10 | 2013-01-16 | GlaxoSmithKline Biologicals S.A. | Vaccine composition |
| TR201802933T4 (tr) * | 2010-03-30 | 2018-03-21 | Childrens Hospital & Res Center At Oakland | Özellikleri değiştirilmiş faktör h bağlama proteinleri (fhbp) ve bunların kullanım yöntemi. |
| WO2011161653A1 (en) | 2010-06-25 | 2011-12-29 | Novartis Ag | Combinations of meningococcal factor h binding proteins |
| MX2014008988A (es) | 2012-02-02 | 2014-08-27 | Novartis Ag | Promotores para aumento de expresion de proteinas en meningococo. |
| ES2847923T3 (es) | 2012-06-14 | 2021-08-04 | Glaxosmithkline Biologicals Sa | Vacunas contra el meningococo del serogrupo X |
| CN104736563A (zh) | 2012-07-27 | 2015-06-24 | 国家健康与医学研究院 | Cd147作为受体用于脑膜炎球菌至血管内皮的菌毛介导的粘附 |
| US20160030544A1 (en) * | 2013-03-14 | 2016-02-04 | Isis Innovation Limited | Immunogenic composition to neisseria |
| WO2015017817A1 (en) | 2013-08-02 | 2015-02-05 | Children's Hospital & Research Center Oakland | Non-naturally occurring factor h binding proteins (fhbp) and methods of use thereof |
| CN106661092B (zh) | 2014-02-28 | 2021-07-06 | 葛兰素史密丝克莱恩生物有限公司 | 修饰的脑膜炎球菌fHbp多肽 |
| BR112017001417B1 (pt) | 2014-07-23 | 2023-11-07 | Children's Hospital & Research Center At Oakland | Variantes da proteína de ligação ao fator h (fhbp), composição imunogênica e uso de uma fhbp variante referência cruzada |
| AU2015304079B2 (en) * | 2014-08-20 | 2021-05-13 | Stichting Sanquin Bloedvoorziening | Factor H potentiating antibodies and uses thereof |
| GB201614687D0 (en) * | 2016-08-31 | 2016-10-12 | Univ Oxford Innovation Ltd | fHbp scaffold |
| EP3607967A1 (en) | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| EP3897706A4 (en) | 2018-12-21 | 2022-11-23 | Griffith University | COMPOSITIONS, METHODS AND USES FOR INDURING AN IMMUNE RESPONSE |
| AU2020309556A1 (en) * | 2019-07-08 | 2022-03-03 | Crapaud Bio, Inc. | Methods of making and using lipooligosaccharide compositions and vaccines |
| JP7631296B2 (ja) | 2019-07-17 | 2025-02-18 | ジェミニ・セラピューティクス・サブ・インコーポレイテッド | Ｈ因子増強性抗体及びその使用 |
| TW202245836A (zh) | 2021-02-19 | 2022-12-01 | 美商賽諾菲巴斯德公司 | 重組ｂ型腦膜炎球菌疫苗 |
| TW202423477A (zh) | 2022-08-03 | 2024-06-16 | 美商賽諾菲巴斯德公司 | 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物 |
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| US4786592A (en) * | 1986-06-18 | 1988-11-22 | Scripps Clinic And Research Foundation | Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin |
| US5476784A (en) * | 1993-04-06 | 1995-12-19 | Rice; Peter A. | Gonococcal anti-idiotypic antibodies and methods and compositions using them |
| GB0220194D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| BRPI0409459A (pt) * | 2003-04-16 | 2006-05-02 | Wyeth Corp | novas composições imunogênicas para a prevenção e tratamento de doença meningocócica |
| CN101107007B (zh) * | 2005-01-27 | 2011-08-17 | 奥克兰儿童医院及研究中心 | 对脑膜炎奈瑟球菌所致疾病具有广谱保护作用的gna1870囊泡疫苗 |
| GB0524066D0 (en) * | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| AU2007263531B2 (en) * | 2006-06-29 | 2012-03-15 | J. Craig Venter Institute, Inc. | Polypeptides from neisseria meningitidis |
| WO2011024072A2 (en) * | 2009-08-27 | 2011-03-03 | Novartis Ag | Hybrid polypeptides including meningococcal fhbp sequences |
| TR201802933T4 (tr) * | 2010-03-30 | 2018-03-21 | Childrens Hospital & Res Center At Oakland | Özellikleri değiştirilmiş faktör h bağlama proteinleri (fhbp) ve bunların kullanım yöntemi. |
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Non-Patent Citations (1)
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| MASIGNANI V ET AL., Vaccination against Neisseria meningitides using three variants of the lipoprotein GNA1870, The Journal of experimental medicine, Rockefeller university press, vol.197, no.6, 17.03.2003, pages 789-799, abstract, figure 6. BEERNINK PETER T ET AL., Prevalence of factor H-binding protein variants and NadA among meningococcal group B isolates from the United States: Implications for the development of a multicomponent group B vaccine, Journal of infectious diseases, University of Chicago press, vol.195, no.10, 15.05.2007, pages 1472-1479, abstract. * |
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