RU2559528C2 - КОМПОЗИЦИИ ВАКЦИН ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ ИНФЕКЦИИ ИЛИ ЗАБОЛЕВАНИЯ, ВЫЗЫВАЕМЫХ Neisseria meningitides И/ИЛИ Neisseria gonorrhoeae, СОДЕРЖАЩИЕ МУТИРОВАННЫЙ БЕЛОК, СВЯЗЫВАЮЩИЙ ФАКТОР Н - Google Patents
КОМПОЗИЦИИ ВАКЦИН ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ ИНФЕКЦИИ ИЛИ ЗАБОЛЕВАНИЯ, ВЫЗЫВАЕМЫХ Neisseria meningitides И/ИЛИ Neisseria gonorrhoeae, СОДЕРЖАЩИЕ МУТИРОВАННЫЙ БЕЛОК, СВЯЗЫВАЮЩИЙ ФАКТОР Н Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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| PCT/GB2009/051439 WO2010046715A1 (en) | 2008-10-25 | 2009-10-26 | Vaccine compositions comprising a mutated factor h binding protein |
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| EP2261339B1 (en) | 1998-05-01 | 2017-03-22 | GlaxoSmithKline Biologicals SA | Neisseria meningitidis antigens and compositions |
| DK2270173T3 (en) | 1999-05-19 | 2016-03-07 | Glaxosmithkline Biolog Sa | Neisserial combination compositions |
| DK1801219T3 (en) | 1999-10-29 | 2015-12-07 | Glaxosmithkline Biolog Sa | Neisseriale antigenic peptides. |
| EP2270031A3 (en) | 2000-02-28 | 2011-02-16 | Novartis Vaccines and Diagnostics S.r.l. | Heterologous expression of neisserial proteins |
| GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| AU2003274511B2 (en) | 2002-10-11 | 2009-06-04 | Glaxosmithkline Biologicals S.A. | Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| US9579372B2 (en) | 2008-02-21 | 2017-02-28 | Glaxosmithkline Biologicals Sa | Meningococcal fHBP polypeptides |
| EP2265640B1 (en) | 2008-03-10 | 2015-11-04 | Children's Hospital & Research Center at Oakland | Chimeric factor h binding proteins (fhbp) containing a heterologous b domain and methods of use |
| BRPI1009828A2 (pt) | 2009-03-24 | 2019-03-12 | Novartis Ag | adjuvante de proteína de ligação de fator h meningocócica |
| AU2010242905B2 (en) | 2009-04-30 | 2014-10-23 | Children's Hospital & Research Center At Oakland | Chimeric factor H binding proteins (fHbp) and methods of use |
| BR112012010531A2 (pt) * | 2009-10-27 | 2019-09-24 | Novartis Ag | "polipeptídeos de modificação meningocócica fhbp" |
| BR112012022669A2 (pt) * | 2010-03-10 | 2017-02-14 | Glaxosmithkline Biologicals Sa | composição imunogênica, método de tratamento ou prevenção de infecção ou doença, uso de um antígeno, kit, métodos para a fabricação de uma composição imunogênica e para melhorar uma vacina. |
| BR112012024348B1 (pt) | 2010-03-30 | 2022-11-08 | Children's Hospital & Research Center At Oakland | Composição imunogênica, seu uso, proteína de ligação ao fator h de ocorrência não natural, e célula bacteriana geneticamente modificada |
| US10478483B2 (en) | 2010-06-25 | 2019-11-19 | Glaxosmithkline Biologicals Sa | Combinations of meningococcal factor H binding proteins |
| CA2861946A1 (en) | 2012-02-02 | 2013-08-08 | Novartis Ag | Promoters for increased protein expression in meningococcus |
| RU2644340C2 (ru) | 2012-06-14 | 2018-02-08 | Новартис Аг | Вакцины для менингококка серогруппы х |
| HK1205138A1 (en) | 2012-07-27 | 2015-12-11 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia |
| WO2014140562A1 (en) * | 2013-03-14 | 2014-09-18 | Isis Innovation Limited | Immunogenic composition to neisseria |
| KR20160034401A (ko) | 2013-08-02 | 2016-03-29 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 비-천연적으로 발생하는 인자 h 결합 단백질(fhbp) 및 이의 사용 방법 |
| AU2015222121B2 (en) | 2014-02-28 | 2018-01-18 | Glaxosmithkline Biologicals Sa | Modified meningococcal fHbp polypeptides |
| CN119613509A (zh) | 2014-07-23 | 2025-03-14 | 奥克兰儿童医院及研究中心 | 因子h结合蛋白变体及其使用方法 |
| BR122023020102A2 (pt) * | 2014-08-20 | 2023-12-12 | Stichting Sanquin Bloedvoorziening | Anticorpos de potenciamento do fator h e seus usos |
| GB201614687D0 (en) * | 2016-08-31 | 2016-10-12 | Univ Oxford Innovation Ltd | fHbp scaffold |
| EP3607967A1 (en) | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| KR20210119397A (ko) | 2018-12-21 | 2021-10-05 | 그리피스 유니버시티 | 면역 반응을 유도하기 위한 조성물, 방법 및 용도 |
| EP3997108A4 (en) * | 2019-07-08 | 2024-03-20 | Crapaud Bio, Inc. | METHODS OF PRODUCING AND USING LIPOOLIGOSACCHARIDE COMPOSITIONS AND VACCINES |
| CA3147638A1 (en) | 2019-07-17 | 2021-01-21 | Gemini Therapeutics Sub, Inc. | Factor h potentiating antibodies and uses thereof |
| JP2024507828A (ja) | 2021-02-19 | 2024-02-21 | サノフィ パスツール インコーポレイテッド | Ｂ群髄膜炎菌組換えワクチン |
| TW202423477A (zh) | 2022-08-03 | 2024-06-16 | 美商賽諾菲巴斯德公司 | 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物 |
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| US4786592A (en) * | 1986-06-18 | 1988-11-22 | Scripps Clinic And Research Foundation | Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin |
| US5476784A (en) * | 1993-04-06 | 1995-12-19 | Rice; Peter A. | Gonococcal anti-idiotypic antibodies and methods and compositions using them |
| GB0220194D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| US20070253964A1 (en) * | 2003-04-16 | 2007-11-01 | Zlotnick Gary W | Novel Immunogenic Compositions for the Prevention and Treatment of Meningococcal Disease |
| US9034345B2 (en) * | 2005-01-27 | 2015-05-19 | Children's Hospital & Research Center Oakland | GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
| GB0524066D0 (en) * | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| RU2450019C2 (ru) * | 2006-06-29 | 2012-05-10 | Новартис Аг | Полипептиды из neisseria meningitidis |
| NZ598458A (en) * | 2009-08-27 | 2014-03-28 | Novartis Ag | Hybrid polypeptides including meningococcal fhbp sequences |
| BR112012024348B1 (pt) * | 2010-03-30 | 2022-11-08 | Children's Hospital & Research Center At Oakland | Composição imunogênica, seu uso, proteína de ligação ao fator h de ocorrência não natural, e célula bacteriana geneticamente modificada |
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2008
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Non-Patent Citations (1)
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| MASIGNANI V ET AL., Vaccination against Neisseria meningitides using three variants of the lipoprotein GNA1870, The Journal of experimental medicine, Rockefeller university press, vol.197, no.6, 17.03.2003, pages 789-799, abstract, figure 6. BEERNINK PETER T ET AL., Prevalence of factor H-binding protein variants and NadA among meningococcal group B isolates from the United States: Implications for the development of a multicomponent group B vaccine, Journal of infectious diseases, University of Chicago press, vol.195, no.10, 15.05.2007, pages 1472-1479, abstract. * |
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