CN102245202A - 含有突变型h因子结合蛋白的疫苗组合物 - Google Patents

含有突变型h因子结合蛋白的疫苗组合物 Download PDF

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Publication number
CN102245202A
CN102245202A CN2009801480003A CN200980148000A CN102245202A CN 102245202 A CN102245202 A CN 102245202A CN 2009801480003 A CN2009801480003 A CN 2009801480003A CN 200980148000 A CN200980148000 A CN 200980148000A CN 102245202 A CN102245202 A CN 102245202A
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China
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factor
composition
binding protein
immune response
human
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CN2009801480003A
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English (en)
Chinese (zh)
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R·埃克斯利
C·唐
S·M·利亚
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Ip2ipo Innovations Ltd
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Imperial Innovations Ltd
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Application filed by Imperial Innovations Ltd filed Critical Imperial Innovations Ltd
Priority to CN201510119007.XA priority Critical patent/CN105412920A/zh
Publication of CN102245202A publication Critical patent/CN102245202A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2009801480003A 2008-10-25 2009-10-26 含有突变型h因子结合蛋白的疫苗组合物 Pending CN102245202A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510119007.XA CN105412920A (zh) 2008-10-25 2009-10-26 含有突变型ｈ因子结合蛋白的疫苗组合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0819633.9A GB0819633D0 (en) 2008-10-25 2008-10-25 Composition
GB0819633.9 2008-10-25
PCT/GB2009/051439 WO2010046715A1 (en) 2008-10-25 2009-10-26 Vaccine compositions comprising a mutated factor h binding protein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201510119007.XA Division CN105412920A (zh) 2008-10-25 2009-10-26 含有突变型ｈ因子结合蛋白的疫苗组合物

Publications (1)

Publication Number Publication Date
CN102245202A true CN102245202A (zh) 2011-11-16

Family

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Family Applications (2)

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CN2009801480003A Pending CN102245202A (zh) 2008-10-25 2009-10-26 含有突变型h因子结合蛋白的疫苗组合物
CN201510119007.XA Pending CN105412920A (zh) 2008-10-25 2009-10-26 含有突变型ｈ因子结合蛋白的疫苗组合物

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CN201510119007.XA Pending CN105412920A (zh) 2008-10-25 2009-10-26 含有突变型ｈ因子结合蛋白的疫苗组合物

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Country Link
US (1) US20120052092A1 (enExample)
EP (2) EP3501534B1 (enExample)
JP (2) JP5676458B2 (enExample)
KR (3) KR20170000390A (enExample)
CN (2) CN102245202A (enExample)
AU (1) AU2009306114B2 (enExample)
BR (1) BRPI0919926A2 (enExample)
CA (1) CA2741619A1 (enExample)
CO (1) CO6382140A2 (enExample)
DK (1) DK3501534T5 (enExample)
ES (1) ES2970878T3 (enExample)
FI (1) FI3501534T3 (enExample)
GB (1) GB0819633D0 (enExample)
HR (1) HRP20240226T1 (enExample)
HU (1) HUE065348T2 (enExample)
LT (1) LT3501534T (enExample)
MX (1) MX2011004322A (enExample)
NZ (2) NZ592444A (enExample)
PL (1) PL3501534T3 (enExample)
PT (1) PT3501534T (enExample)
RU (1) RU2559528C2 (enExample)
SI (1) SI3501534T1 (enExample)
WO (1) WO2010046715A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107074939A (zh) * 2014-08-20 2017-08-18 桑昆血液供给基金会 H因子增强抗体及其用途

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DK1093517T3 (da) 1998-05-01 2008-06-23 Novartis Vaccines & Diagnostic Neisseria-meningitidis-antigener og præparater
NZ515935A (en) 1999-05-19 2004-01-30 Chiron S Combination Neisserial compositions and vaccines for the prevention of infections due to Neisseria bacteria such as meningococcal meningitis
EP2275553B1 (en) 1999-10-29 2015-05-13 Novartis Vaccines and Diagnostics S.r.l. Neisserial antigenic peptides
JP4763210B2 (ja) 2000-02-28 2011-08-31 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル ナイセリアのタンパク質の異種発現
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
MXPA05003863A (es) 2002-10-11 2005-09-08 Chiron Srl Vacunas polipeptidicas para amplia proteccion contra lineas hipervirulentas de meningococos.
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
NZ587382A (en) 2008-02-21 2012-01-12 Novartis Ag Meningococcal fhbp polypeptides
EP2265640B1 (en) 2008-03-10 2015-11-04 Children's Hospital & Research Center at Oakland Chimeric factor h binding proteins (fhbp) containing a heterologous b domain and methods of use
NZ595234A (en) 2009-03-24 2013-12-20 Novartis Ag Adjuvanting meningococcal factor h binding protein
WO2010127172A2 (en) 2009-04-30 2010-11-04 Children's Hospital & Research Center At Oakland Chimeric factor h binding proteins (fhbp) and methods of use
WO2011051893A1 (en) 2009-10-27 2011-05-05 Novartis Ag Modified meningococcal fhbp polypeptides
WO2011110634A1 (en) * 2010-03-10 2011-09-15 Glaxosmithkline Biologicals S.A. Vaccine composition
CN110845585A (zh) * 2010-03-30 2020-02-28 奥克兰儿童医院及研究中心 改性的h因子结合蛋白（fhbp）及其使用方法
EP2585106A1 (en) 2010-06-25 2013-05-01 Novartis AG Combinations of meningococcal factor h binding proteins
EP2809785B1 (en) 2012-02-02 2017-11-01 GlaxoSmithKline Biologicals SA Promoters for increased protein expression in meningococcus
WO2013186753A1 (en) 2012-06-14 2013-12-19 Novartis Ag Vaccines for serogroup x meningococcus
CA2875391A1 (en) 2012-07-27 2014-01-30 Institut National De La Sante Et De La Recherche Medicale Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
WO2014140562A1 (en) * 2013-03-14 2014-09-18 Isis Innovation Limited Immunogenic composition to neisseria
EP3027206A4 (en) 2013-08-02 2017-03-08 Children's Hospital & Research Center Oakland Non-naturally occurring factor h binding proteins (fhbp) and methods of use thereof
SI3110442T1 (sl) 2014-02-28 2021-01-29 Glaxosmithkline Biologicals S.A. Modificirani meningokokni fHbp polipeptidi
EP3172224B1 (en) 2014-07-23 2022-06-29 Children's Hospital & Research Center at Oakland Factor h binding protein variants and methods of use thereof
GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
WO2020124159A1 (en) 2018-12-21 2020-06-25 Griffith University Compositions, methods and uses for eliciting an immune response
WO2021007365A1 (en) * 2019-07-08 2021-01-14 Crapaud Bio, Inc. Methods of making and using lipooligosaccharide compositions and vaccines
BR112022000739A2 (pt) 2019-07-17 2022-04-12 Gemini Therapeutics Sub Inc Anticorpos de potencialização de fator h e usos dos mesmos
MX2023009728A (es) 2021-02-19 2023-08-30 Sanofi Pasteur Inc Vacuna recombinante meningococica b.
TW202423477A (zh) 2022-08-03 2024-06-16 美商賽諾菲巴斯德公司 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物

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CN1124456A (zh) * 1993-04-06 1996-06-12 波士顿市健康与医院理事会 淋球菌抗个体基因型抗体及其使用方法和组合物

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CN110845585A (zh) * 2010-03-30 2020-02-28 奥克兰儿童医院及研究中心 改性的h因子结合蛋白（fhbp）及其使用方法

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CN87104828A (zh) * 1986-06-18 1988-05-04 斯克里普斯临床学与研究基金会 用作疫苗和诊断标记的淋病奈瑟氏菌植物凝血素及其制备方法
CN1124456A (zh) * 1993-04-06 1996-06-12 波士顿市健康与医院理事会 淋球菌抗个体基因型抗体及其使用方法和组合物

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107074939A (zh) * 2014-08-20 2017-08-18 桑昆血液供给基金会 H因子增强抗体及其用途
CN107074939B (zh) * 2014-08-20 2021-09-07 桑昆血液供给基金会 H因子增强抗体及其用途

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Publication number Publication date
CO6382140A2 (es) 2012-02-15
CN105412920A (zh) 2016-03-23
PT3501534T (pt) 2024-02-07
AU2009306114A1 (en) 2010-04-29
JP6076326B2 (ja) 2017-02-08
KR20190011836A (ko) 2019-02-07
DK3501534T3 (da) 2024-02-05
RU2011120706A (ru) 2012-11-27
SI3501534T1 (sl) 2024-03-29
EP2355845A1 (en) 2011-08-17
LT3501534T (lt) 2024-03-12
ES2970878T3 (es) 2024-05-31
KR20110092282A (ko) 2011-08-17
MX2011004322A (es) 2011-06-16
GB0819633D0 (en) 2008-12-03
KR20170000390A (ko) 2017-01-02
BRPI0919926A2 (pt) 2016-02-16
HUE065348T2 (hu) 2024-05-28
EP3501534B1 (en) 2023-11-29
NZ601538A (en) 2014-01-31
DK3501534T5 (da) 2024-09-02
EP3501534A1 (en) 2019-06-26
JP2015063558A (ja) 2015-04-09
CA2741619A1 (en) 2010-04-29
NZ592444A (en) 2012-11-30
US20120052092A1 (en) 2012-03-01
JP5676458B2 (ja) 2015-02-25
WO2010046715A1 (en) 2010-04-29
RU2559528C2 (ru) 2015-08-10
AU2009306114B2 (en) 2015-10-01
EP2355845B1 (en) 2018-12-05
FI3501534T3 (fi) 2024-02-09
HRP20240226T1 (hr) 2024-05-10
JP2012506411A (ja) 2012-03-15
PL3501534T3 (pl) 2024-04-02

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