KR20180041087A - 암을 치료하기 위한 방법 및 조성물 - Google Patents
암을 치료하기 위한 방법 및 조성물 Download PDFInfo
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- KR20180041087A KR20180041087A KR1020177018139A KR20177018139A KR20180041087A KR 20180041087 A KR20180041087 A KR 20180041087A KR 1020177018139 A KR1020177018139 A KR 1020177018139A KR 20177018139 A KR20177018139 A KR 20177018139A KR 20180041087 A KR20180041087 A KR 20180041087A
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| US9512194B2 (en) | 2012-01-27 | 2016-12-06 | The Board Of Trustees Of The Leland Stanford Junior University | Modified IL-13 polypeptides |
| JP6445434B2 (ja) | 2012-08-09 | 2018-12-26 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | スーパーカインおよびシンセカイン:新規かつ増強されたシグナル伝達活性を有する再利用されるサイトカイン |
| US20150320799A1 (en) | 2012-12-20 | 2015-11-12 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| BR112017011771A2 (pt) | 2014-12-02 | 2018-07-10 | Prospect Chartercare Rwmc Llc | métodos e composições para o tratamento de câncer |
| PT3310805T (pt) * | 2015-06-19 | 2021-05-19 | Kobold Sebastian | Proteínas de fusão pd-1-cd28 e a sua utilização em medicina |
| ES2877090T3 (es) * | 2015-08-05 | 2021-11-16 | Cellabmed Inc | Receptor de antígenos quiméricos y células T en las que se expresa el receptor de antígenos quiméricos |
| JP7282521B2 (ja) | 2016-04-08 | 2023-05-29 | パーデュー・リサーチ・ファウンデイション | Car t細胞療法のための方法および組成物 |
| WO2018112266A1 (en) * | 2016-12-14 | 2018-06-21 | The Board Of Trustees Of The Leland Stanford Junior University | Il-13 superkine: immune cell targeting constructs and methods of use thereof |
| EP3579870A4 (en) | 2017-02-07 | 2020-12-30 | Seattle Children's Hospital (DBA Seattle Children's Research Institute) | PHOSPHOLIPID ETHER (PLE) T CAR-LYMPHOCYTE TUMOR (CTCT) TARGETING AGENTS |
| WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
| CN110753555A (zh) | 2017-04-19 | 2020-02-04 | 得克萨斯州大学系统董事会 | 表达工程化抗原受体的免疫细胞 |
| WO2019073299A1 (en) | 2017-10-10 | 2019-04-18 | Medicenna Therapeutics, Inc. | IL-4 FUSION FORMULATIONS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM (CNS) TUMORS |
| WO2019100079A1 (en) * | 2017-11-20 | 2019-05-23 | Prospect CharterCare RWMC, LLC d/b/a Roger Williams Medical Center | Compositions for improving car-t cell functionality and user thereof |
| KR20250010750A (ko) * | 2017-12-20 | 2025-01-21 | 포세이다 테라퓨틱스, 인크. | Vcar 조성물 및 사용 방법 |
| AU2019209432A1 (en) | 2018-01-22 | 2020-08-06 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for CAR T cells |
| US11701405B2 (en) * | 2018-01-26 | 2023-07-18 | City Of Hope | Chimeric antigen receptors and methods for reducing toxicity |
| CN111936518A (zh) | 2018-02-06 | 2020-11-13 | 西雅图儿童医院(Dba西雅图儿童研究所) | 对fl-ple标记的肿瘤表现出最佳的t细胞功能的荧光素特异性car |
| CN110157674A (zh) * | 2018-02-12 | 2019-08-23 | 深圳宾德生物技术有限公司 | 一种靶向性t淋巴细胞及其制备方法和应用 |
| CN110144326A (zh) * | 2018-02-12 | 2019-08-20 | 深圳宾德生物技术有限公司 | 一种靶向性抗肿瘤t细胞及其制备方法和应用 |
| EP3755349A4 (en) | 2018-02-21 | 2021-11-17 | Board of Regents, The University of Texas System | PROCESS FOR ACTIVATION AND EXPANSION OF NATURAL KILLER CELLS AND THEIR USES |
| WO2019165237A1 (en) | 2018-02-23 | 2019-08-29 | Endocyte, Inc. | Sequencing method for car t cell therapy |
| CN108440674A (zh) * | 2018-04-28 | 2018-08-24 | 杭州荣泽生物科技有限公司 | 一种Trop-2特异性嵌合抗原受体细胞制备及其用途 |
| US12404497B2 (en) | 2018-06-01 | 2025-09-02 | Medicenna Therapeutics Inc. | Uses and methods for oncolytic virus targeting of IL-4/IL-13 and fusions thereof |
| JP2023512250A (ja) * | 2020-01-31 | 2023-03-24 | シティ・オブ・ホープ | IL13Rα2陽性悪性腫瘍の治療のための標的キメラ抗原受容体修飾T細胞 |
| WO2021241719A1 (ja) * | 2020-05-28 | 2021-12-02 | 中外製薬株式会社 | 改良されたグランザイムb改変体 |
| CA3193009A1 (en) * | 2020-08-26 | 2022-03-03 | The Regents Of The University Of California | Methods and compositions for treating glioblastoma |
| WO2022056398A1 (en) * | 2020-09-11 | 2022-03-17 | University Of Georgia Research Foundation, Inc. | Compositions and methods of use thereof for prevention and treatment of influenza infections |
| EP4263600A1 (en) | 2020-12-18 | 2023-10-25 | Century Therapeutics, Inc. | Chimeric antigen receptor systems with adaptable receptor specificity |
| CN114907485B (zh) * | 2021-02-08 | 2024-04-26 | 浙江大学 | 一种以内源性蛋白质分子替代单结构域抗体的嵌合抗原受体 |
| CN113304267B (zh) * | 2021-06-11 | 2022-03-15 | 河南大学 | 肺癌的治疗靶点及其应用 |
| CN114014941B (zh) * | 2022-01-10 | 2022-04-12 | 卡瑞济(北京)生命科技有限公司 | 靶向IL13Rα2的嵌合抗原受体及其用途 |
| CN116549667B (zh) * | 2023-05-29 | 2024-02-09 | 四川普锐特药业有限公司 | 一种pas修饰的脂质纳米粒、包含其的药物制剂,及其制备方法和用途 |
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| EP1222289B1 (en) * | 1999-10-20 | 2008-04-16 | The Johns Hopkins University School Of Medicine | Chimeric immunogenic compositions and nucleic acids encoding them |
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| AU2003223497A1 (en) * | 2002-04-05 | 2003-10-27 | Centocor, Inc. | Asthma-related anti-il-13 immunoglobulin derived proteins, compositions, methods and uses |
| US7709625B2 (en) * | 2004-06-10 | 2010-05-04 | The Board Of Regents Of The University Of Texas | Methods and compositions for bone marrow stem cell-derived macrophage delivery of genes for gene therapy |
| WO2007075077A1 (es) * | 2005-11-16 | 2007-07-05 | Universidad Nacional Autonoma De Mexico | Uso de agentes modificantes del transcriptoma más quimioterapia o radioterapia contra el cáncer |
| CN101438158A (zh) * | 2006-03-06 | 2009-05-20 | 阿穆尼克斯股份有限公司 | 遗传包和其应用 |
| US20080206139A1 (en) * | 2006-11-03 | 2008-08-28 | The Penn State Research Foundation | Delivery system for diagnostic and therapeutic agents |
| PL3006459T3 (pl) * | 2008-08-26 | 2022-01-17 | City Of Hope | Sposób i kompozycje dla wzmocnionego działania efektorowego komórek t przeciw guzowi nowotworowemu |
| US9273283B2 (en) * | 2009-10-29 | 2016-03-01 | The Trustees Of Dartmouth College | Method of producing T cell receptor-deficient T cells expressing a chimeric receptor |
| ES2621874T3 (es) * | 2010-03-26 | 2017-07-05 | Memorial Sloan-Kettering Cancer Center | Anticuerpos para MUC16 y métodos de uso de los mismos |
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| LT2956175T (lt) * | 2013-02-15 | 2017-12-11 | The Regents Of The University Of California | Chimerinis antigeno receptorius ir jo panaudojimo būdai |
| EP2968601A1 (en) * | 2013-03-10 | 2016-01-20 | Baylor College Of Medicine | Chemotherapy-resistant immune cells |
| ES2792849T3 (es) | 2014-02-10 | 2020-11-12 | Univ Emory | Expresión de polipéptido químico con receptores de linfocitos variables en células inmunes y usos para tratar el cáncer |
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- 2015-12-02 UY UY0001036418A patent/UY36418A/es not_active Application Discontinuation
- 2015-12-02 TW TW104140317A patent/TW201636425A/zh unknown
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2017
- 2017-05-09 US US15/590,961 patent/US20180072789A1/en not_active Abandoned
- 2017-06-01 IL IL252610A patent/IL252610A0/en unknown
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Also Published As
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| CN107709353A (zh) | 2018-02-16 |
| US20180072789A1 (en) | 2018-03-15 |
| MX2017007272A (es) | 2018-06-06 |
| BR112017011771A2 (pt) | 2018-07-10 |
| AU2015355084A1 (en) | 2017-06-29 |
| US9650428B2 (en) | 2017-05-16 |
| SG10202103475XA (en) | 2021-05-28 |
| SG11201704519YA (en) | 2017-07-28 |
| WO2016089916A1 (en) | 2016-06-09 |
| HK1251862A1 (zh) | 2019-04-26 |
| JP2017537622A (ja) | 2017-12-21 |
| EA201791210A1 (ru) | 2017-11-30 |
| CA2969714A1 (en) | 2016-06-09 |
| EP3227317A1 (en) | 2017-10-11 |
| US20160151490A1 (en) | 2016-06-02 |
| EP3227317A4 (en) | 2018-04-25 |
| AR102879A1 (es) | 2017-03-29 |
| IL252610A0 (en) | 2017-07-31 |
| TW201636425A (zh) | 2016-10-16 |
| UY36418A (es) | 2016-06-30 |
| PH12017501031A1 (en) | 2017-11-27 |
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