KR20170128348A - 인슐린 내성의 치료를 위한 전사 인자 tsc22d4를 표적으로 하는 올리고뉴클레오타이드 서열 - Google Patents

인슐린 내성의 치료를 위한 전사 인자 tsc22d4를 표적으로 하는 올리고뉴클레오타이드 서열 Download PDF

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KR20170128348A
KR20170128348A KR1020177026584A KR20177026584A KR20170128348A KR 20170128348 A KR20170128348 A KR 20170128348A KR 1020177026584 A KR1020177026584 A KR 1020177026584A KR 20177026584 A KR20177026584 A KR 20177026584A KR 20170128348 A KR20170128348 A KR 20170128348A
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insulin resistance
tsc22d4
insulin
sirna
treatment
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Korean (ko)
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스테판 헤르지크
디아즈 마우리치오 베르릴
토비아스 샤프마이어
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도이체스크레브스포르슝스젠트룸스티프퉁데스외펜트리헨레크츠
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/318—Chemical structure of the backbone where the PO2 is completely replaced, e.g. MMI or formacetal
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C12N2310/531—Stem-loop; Hairpin

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  • Diabetes (AREA)
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  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020177026584A 2015-03-23 2016-02-12 인슐린 내성의 치료를 위한 전사 인자 tsc22d4를 표적으로 하는 올리고뉴클레오타이드 서열 Ceased KR20170128348A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15160259.6A EP3072969A1 (en) 2015-03-23 2015-03-23 Oligonucleotide sequences targeting transcription factor TSC22D4 for the treatment of insulin resistance
EP15160259.6 2015-03-23
PCT/EP2016/053050 WO2016150618A1 (en) 2015-03-23 2016-02-12 Oligonucleotide sequences targeting transcription factor tsc22d4 for the treatment of insulin resistance

Publications (1)

Publication Number Publication Date
KR20170128348A true KR20170128348A (ko) 2017-11-22

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KR1020177026584A Ceased KR20170128348A (ko) 2015-03-23 2016-02-12 인슐린 내성의 치료를 위한 전사 인자 tsc22d4를 표적으로 하는 올리고뉴클레오타이드 서열

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Country Link
US (2) US10676739B2 (enExample)
EP (2) EP3072969A1 (enExample)
JP (1) JP2018513841A (enExample)
KR (1) KR20170128348A (enExample)
CN (1) CN107278229A (enExample)
BR (1) BR112017016021A2 (enExample)
DK (1) DK3274455T3 (enExample)
ES (1) ES2837085T3 (enExample)
MX (1) MX384193B (enExample)
RU (1) RU2723091C2 (enExample)
WO (1) WO2016150618A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7289510B2 (ja) * 2019-05-08 2023-06-12 国立大学法人高知大学 認知症治療薬のスクリーニング方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2377385A1 (en) * 1999-06-03 2000-12-14 Jessie L.S. Au Methods and compositions for modulating cell proliferation and cell death
EP2305813A3 (en) * 2002-11-14 2012-03-28 Dharmacon, Inc. Fuctional and hyperfunctional sirna
EP1692521A1 (en) 2003-12-11 2006-08-23 Beth Israel Deaconess Medical Center, Inc. Rbp4 in insulin sensitivity/resistance, diabetes, and obesity
CA2566286A1 (en) * 2004-05-11 2005-12-08 Rnai Co., Ltd. Polynucleotide causing rna interfere and method of regulating gene expression with the use of the same
US7943306B2 (en) * 2005-01-12 2011-05-17 The Board Of Trustees Of The Leland Stanford Junior University Gene expression signature for prediction of human cancer progression
US20140227289A1 (en) 2011-05-13 2014-08-14 Stephen Michael Cohen Compounds and methods for treating insulin resistance syndrome
GB201120317D0 (en) 2011-11-24 2012-01-04 Queen Mary & Westfield College Screening method
EP2816356A1 (en) 2013-06-17 2014-12-24 Ruprecht-Karls-Universität Heidelberg Treatment of insulin resistance through inhibitors of transcription factor TSC22D4
RU2573450C1 (ru) * 2014-08-11 2016-01-20 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Способ выявления генов-мишеней для диагностики и терапии лейкозов человека

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Publication number Publication date
MX384193B (es) 2025-03-12
EP3274455A1 (en) 2018-01-31
US20180023078A1 (en) 2018-01-25
US20200255834A1 (en) 2020-08-13
RU2017131900A3 (enExample) 2019-06-10
EP3072969A1 (en) 2016-09-28
BR112017016021A2 (pt) 2018-03-20
RU2017131900A (ru) 2019-04-23
DK3274455T3 (da) 2020-12-14
EP3274455B1 (en) 2020-10-14
JP2018513841A (ja) 2018-05-31
RU2723091C2 (ru) 2020-06-08
US10676739B2 (en) 2020-06-09
WO2016150618A1 (en) 2016-09-29
CA2979115A1 (en) 2016-09-29
US11053499B2 (en) 2021-07-06
MX2017012231A (es) 2018-01-30
ES2837085T3 (es) 2021-06-29
CN107278229A (zh) 2017-10-20

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