KR20170013890A - Nmdar 조절 화합물의 조합물 - Google Patents

Nmdar 조절 화합물의 조합물 Download PDF

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Publication number
KR20170013890A
KR20170013890A KR1020167034031A KR20167034031A KR20170013890A KR 20170013890 A KR20170013890 A KR 20170013890A KR 1020167034031 A KR1020167034031 A KR 1020167034031A KR 20167034031 A KR20167034031 A KR 20167034031A KR 20170013890 A KR20170013890 A KR 20170013890A
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South Korea
Prior art keywords
nmdar antagonist
glyx
group
nmdar
antagonist
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Korean (ko)
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조셉 알. 모스칼
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노쓰웨스턴유니버시티
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Priority to KR1020227022906A priority Critical patent/KR20220102662A/ko
Publication of KR20170013890A publication Critical patent/KR20170013890A/ko
Ceased legal-status Critical Current

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  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020167034031A 2014-05-06 2015-05-06 Nmdar 조절 화합물의 조합물 Ceased KR20170013890A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227022906A KR20220102662A (ko) 2014-05-06 2015-05-06 Nmdar 조절 화합물의 조합물

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461989183P 2014-05-06 2014-05-06
US61/989,183 2014-05-06
PCT/US2015/029477 WO2015171770A1 (en) 2014-05-06 2015-05-06 Combinations of nmdar modulating compounds

Related Child Applications (1)

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KR1020227022906A Division KR20220102662A (ko) 2014-05-06 2015-05-06 Nmdar 조절 화합물의 조합물

Publications (1)

Publication Number Publication Date
KR20170013890A true KR20170013890A (ko) 2017-02-07

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KR1020167034031A Ceased KR20170013890A (ko) 2014-05-06 2015-05-06 Nmdar 조절 화합물의 조합물
KR1020227022906A Ceased KR20220102662A (ko) 2014-05-06 2015-05-06 Nmdar 조절 화합물의 조합물

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KR1020227022906A Ceased KR20220102662A (ko) 2014-05-06 2015-05-06 Nmdar 조절 화합물의 조합물

Country Status (11)

Country Link
US (1) US20170072005A1 (https=)
EP (1) EP3139943A4 (https=)
JP (3) JP2017514871A (https=)
KR (2) KR20170013890A (https=)
CN (1) CN106659762A (https=)
AU (1) AU2015256075B2 (https=)
BR (1) BR112016025910A8 (https=)
CA (1) CA2947976A1 (https=)
MX (1) MX2016014581A (https=)
RU (1) RU2721948C2 (https=)
WO (1) WO2015171770A1 (https=)

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KR102613179B1 (ko) 2015-06-01 2023-12-14 뤼겐 홀딩스 (케이맨) 리미티드 Nr2b nmda 수용체 길항제로서의 3,3-디플루오로피페리딘 카바메이트 헤테로사이클릭 화합물
CN108601814A (zh) * 2015-10-16 2018-09-28 西北大学 用于治疗精神分裂症、双相障碍、认知损害和重度抑郁障碍的非典型抗精神病药和nmda调节剂的药物组合
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US11000526B2 (en) 2016-11-22 2021-05-11 Rugen Holdings (Cayman) Limited Treatment of autism spectrum disorders, obsessive-compulsive disorder and anxiety disorders
CN107550907A (zh) * 2017-08-29 2018-01-09 昆明医科大学 治疗精神分裂症的药物及验证药物的动物模型构建方法
RU2020118505A (ru) * 2017-12-05 2022-01-10 Наурекс Инк. Комбинация модуляторов nmda-рецептора (рапастинеля) для применения в комбинированной терапии (расстройства сна и цнс)
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CN110343050B (zh) 2018-04-04 2021-09-24 上海键合医药科技有限公司 芳香类化合物及其制备方法和用途
CN109223785A (zh) * 2018-10-29 2019-01-18 中国药科大学 犬尿喹啉酸或其衍生物在制备改善慢性精神应激相关病理损伤药物中的应用
CN113557028A (zh) * 2019-01-11 2021-10-26 诺雷克斯股份有限公司 雷帕替奈的盐和晶型
EP3923938B1 (en) * 2019-02-14 2025-04-16 Seyltx, Inc. Ifenprodil or radiprodil for treating idiopathic pulmonary fibrosis
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CN113234036B (zh) * 2021-05-12 2023-07-14 斯莱普泰(上海)生物医药科技有限公司 Nmda受体拮抗剂及其用途
WO2024059713A2 (en) 2022-09-14 2024-03-21 The Board Of Trustees Of The Leland Stanford Junior University Compositions of iboga alkaloids and methods of treatment
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WO2025124571A1 (zh) * 2023-12-14 2025-06-19 斯莱普泰(上海)生物医药科技有限公司 Nmda受体拮抗剂及其用途
CN119174765A (zh) * 2024-09-04 2024-12-24 复旦大学附属中山医院 Gsdme蛋白的小分子抑制剂在肿瘤及其免疫治疗中的作用

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CA2947976A1 (en) 2015-11-12
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