KR20160144399A - 톨-유사 수용체 7 효능제로서의 화합물 및 조성물 - Google Patents
톨-유사 수용체 7 효능제로서의 화합물 및 조성물 Download PDFInfo
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- KR20160144399A KR20160144399A KR1020167030102A KR20167030102A KR20160144399A KR 20160144399 A KR20160144399 A KR 20160144399A KR 1020167030102 A KR1020167030102 A KR 1020167030102A KR 20167030102 A KR20167030102 A KR 20167030102A KR 20160144399 A KR20160144399 A KR 20160144399A
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- Prior art keywords
- methyl
- pyrrolo
- pyrimidin
- formula
- amino
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| US201461987314P | 2014-05-01 | 2014-05-01 | |
| US61/987,314 | 2014-05-01 | ||
| PCT/US2015/028285 WO2015168279A1 (en) | 2014-05-01 | 2015-04-29 | Compounds and compositions as toll-like receptor 7 agonists |
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| KR20160144399A true KR20160144399A (ko) | 2016-12-16 |
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| AP2016009485A0 (en) | 2014-05-01 | 2016-10-31 | Novartis Ag | Compounds and compositions as toll-like receptor 7 agonists |
| HUE054672T2 (hu) | 2014-08-15 | 2021-09-28 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | TLR7 agonistaként alkalmazott pirrolopirimidin vegyületek |
| CN105732635A (zh) * | 2014-12-29 | 2016-07-06 | 南京明德新药研发股份有限公司 | 一类Toll样受体7激动剂 |
| MA44334A (fr) * | 2015-10-29 | 2018-09-05 | Novartis Ag | Conjugués d'anticorps comprenant un agoniste du récepteur de type toll |
| CN107043380A (zh) * | 2016-02-05 | 2017-08-15 | 正大天晴药业集团股份有限公司 | 一种tlr7激动剂的马来酸盐、其晶型c、晶型d、晶型e、制备方法和用途 |
| CN107043377A (zh) * | 2016-02-05 | 2017-08-15 | 正大天晴药业集团股份有限公司 | 一种tlr7激动剂的三氟乙酸盐、晶型b及其制备方法、药物组合物和用途 |
| FI3526323T3 (fi) | 2016-10-14 | 2023-06-06 | Prec Biosciences Inc | Hepatiitti B -viruksen genomissa oleville tunnistussekvensseille spesifisiä muokattuja meganukleaaseja |
| AR111651A1 (es) * | 2017-04-28 | 2019-08-07 | Novartis Ag | Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación |
| US10508115B2 (en) | 2017-08-16 | 2019-12-17 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor |
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