KR20160144399A - 톨-유사 수용체 7 효능제로서의 화합물 및 조성물 - Google Patents
톨-유사 수용체 7 효능제로서의 화합물 및 조성물 Download PDFInfo
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- KR20160144399A KR20160144399A KR1020167030102A KR20167030102A KR20160144399A KR 20160144399 A KR20160144399 A KR 20160144399A KR 1020167030102 A KR1020167030102 A KR 1020167030102A KR 20167030102 A KR20167030102 A KR 20167030102A KR 20160144399 A KR20160144399 A KR 20160144399A
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- Prior art keywords
- methyl
- pyrrolo
- pyrimidin
- formula
- amino
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| US201461987314P | 2014-05-01 | 2014-05-01 | |
| US61/987,314 | 2014-05-01 | ||
| PCT/US2015/028285 WO2015168279A1 (en) | 2014-05-01 | 2015-04-29 | Compounds and compositions as toll-like receptor 7 agonists |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR102139847B1 (ko) | 2014-05-01 | 2020-07-31 | 노파르티스 아게 | 톨-유사 수용체 7 효능제로서의 화합물 및 조성물 |
| CN110759916B (zh) | 2014-08-15 | 2021-02-19 | 正大天晴药业集团股份有限公司 | 作为tlr7激动剂的吡咯并嘧啶化合物 |
| CN105732635A (zh) * | 2014-12-29 | 2016-07-06 | 南京明德新药研发股份有限公司 | 一类Toll样受体7激动剂 |
| MA44334A (fr) | 2015-10-29 | 2018-09-05 | Novartis Ag | Conjugués d'anticorps comprenant un agoniste du récepteur de type toll |
| CN107043380A (zh) * | 2016-02-05 | 2017-08-15 | 正大天晴药业集团股份有限公司 | 一种tlr7激动剂的马来酸盐、其晶型c、晶型d、晶型e、制备方法和用途 |
| CN107043377A (zh) * | 2016-02-05 | 2017-08-15 | 正大天晴药业集团股份有限公司 | 一种tlr7激动剂的三氟乙酸盐、晶型b及其制备方法、药物组合物和用途 |
| MA46535A (fr) | 2016-10-14 | 2019-08-21 | Prec Biosciences Inc | Méganucléases modifiées spécifiques de séquences de reconnaissance dans le génome du virus de l'hépatite b |
| AR111651A1 (es) * | 2017-04-28 | 2019-08-07 | Novartis Ag | Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación |
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