KR20160127714A - 아제판 유도체 및 b형 간염 감염의 치료 방법 - Google Patents
아제판 유도체 및 b형 간염 감염의 치료 방법Info
- Publication number
- KR20160127714A KR20160127714A KR1020167015390A KR20167015390A KR20160127714A KR 20160127714 A KR20160127714 A KR 20160127714A KR 1020167015390 A KR1020167015390 A KR 1020167015390A KR 20167015390 A KR20167015390 A KR 20167015390A KR 20160127714 A KR20160127714 A KR 20160127714A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- alkylene
- hbv
- alkyl
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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| DE10012823A1 (de) * | 2000-03-16 | 2001-09-20 | Bayer Ag | Arzneimittel gegen virale Erkrankungen |
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| BR112014015197A8 (pt) | 2011-12-21 | 2017-06-13 | Novira Therapeutics Inc | agentes antivirais de hepatite b |
| WO2015073774A1 (en) | 2013-11-14 | 2015-05-21 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis b infections |
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| EP3068774A1 (en) | 2016-09-21 |
| US9758489B2 (en) | 2017-09-12 |
| US20180044300A1 (en) | 2018-02-15 |
| JP2019089792A (ja) | 2019-06-13 |
| AU2014348518B2 (en) | 2019-01-03 |
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| CN106255684A (zh) | 2016-12-21 |
| EA201690979A1 (ru) | 2016-08-31 |
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| ES2777248T3 (es) | 2020-08-04 |
| US10364228B2 (en) | 2019-07-30 |
| US9115113B2 (en) | 2015-08-25 |
| AU2014348518A1 (en) | 2016-05-19 |
| US20150132258A1 (en) | 2015-05-14 |
| EP3068774A4 (en) | 2017-07-26 |
| EP3068774B1 (en) | 2019-12-25 |
| JP2016537368A (ja) | 2016-12-01 |
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