KR20160043128A - 항-notch1 nrr 항체 및 그것을 이용한 방법 - Google Patents

항-notch1 nrr 항체 및 그것을 이용한 방법 Download PDF

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Publication number
KR20160043128A
KR20160043128A KR1020167008809A KR20167008809A KR20160043128A KR 20160043128 A KR20160043128 A KR 20160043128A KR 1020167008809 A KR1020167008809 A KR 1020167008809A KR 20167008809 A KR20167008809 A KR 20167008809A KR 20160043128 A KR20160043128 A KR 20160043128A
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Prior art keywords
antibody
notch1
antibodies
sequence
cells
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Abandoned
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Korean (ko)
Inventor
크리스쳔 더블유. 시에벨
얀 유
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제넨테크, 인크.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39735560&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20160043128(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 제넨테크, 인크. filed Critical 제넨테크, 인크.
Publication of KR20160043128A publication Critical patent/KR20160043128A/ko
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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KR1020167008809A 2007-06-04 2008-06-03 항-notch1 nrr 항체 및 그것을 이용한 방법 Abandoned KR20160043128A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US93307207P 2007-06-04 2007-06-04
US60/933,072 2007-06-04
US99464607P 2007-09-20 2007-09-20
US60/994,646 2007-09-20
PCT/US2008/007000 WO2008150525A1 (en) 2007-06-04 2008-06-03 Anti-notch1 nrr antibodies and methods using same

Related Parent Applications (1)

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KR1020097025300A Division KR20100021581A (ko) 2007-06-04 2008-06-03 항-notch1 nrr 항체 및 그것을 이용한 방법

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KR20160043128A true KR20160043128A (ko) 2016-04-20

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KR1020097025300A Ceased KR20100021581A (ko) 2007-06-04 2008-06-03 항-notch1 nrr 항체 및 그것을 이용한 방법
KR1020167008809A Abandoned KR20160043128A (ko) 2007-06-04 2008-06-03 항-notch1 nrr 항체 및 그것을 이용한 방법

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US (5) US8846871B2 (enExample)
EP (1) EP2152748B1 (enExample)
JP (4) JP5623272B2 (enExample)
KR (2) KR20100021581A (enExample)
CN (1) CN101796074B (enExample)
AR (1) AR066846A1 (enExample)
BR (1) BRPI0811382A2 (enExample)
CA (1) CA2687866C (enExample)
CL (1) CL2008001634A1 (enExample)
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CR (2) CR11139A (enExample)
CY (1) CY1114690T1 (enExample)
DK (1) DK2152748T3 (enExample)
EC (1) ECSP099785A (enExample)
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HR (1) HRP20131107T1 (enExample)
IL (3) IL202183A0 (enExample)
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MX (1) MX2009013199A (enExample)
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PL (1) PL2152748T3 (enExample)
PT (1) PT2152748E (enExample)
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SI (1) SI2152748T1 (enExample)
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US7919092B2 (en) 2006-06-13 2011-04-05 Oncomed Pharmaceuticals, Inc. Antibodies to notch receptors
CL2007002989A1 (es) 2006-10-19 2008-05-16 Genentech Inc Anticuerpos anti-notch3; acido nucleico que los codifica; vector y celula que lo comprende; metodo de produccion; y su uso para el diagnostico de enfermedades relacionadas con notch3.
CA2666672A1 (en) 2006-10-19 2008-05-02 Genentech, Inc. Anti-notch3 agonist antibodies and their use in the treatment of notch3-related diseases
AU2007333805B2 (en) 2006-12-18 2013-07-25 Genentech, Inc. Antagonist anti-Notch3 antibodies and their use in the prevention and treatment of Notch3-related diseases
JP5618544B2 (ja) 2007-01-24 2014-11-05 オンコメッドファーマシューティカルズ インコーポレイテッド 癌の診断および処置のための組成物および方法
PE20090321A1 (es) 2007-06-04 2009-04-20 Genentech Inc Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
US9132189B2 (en) 2008-07-08 2015-09-15 Oncomed Pharmaceuticals, Inc. Notch1 binding agents and methods of use thereof
MX2011000233A (es) 2008-07-08 2011-05-19 Oncomed Pharm Inc Agentes de union del receptor notch1 y metodos para su uso.
US8404239B2 (en) * 2008-10-01 2013-03-26 Genentech, Inc. Anti-Notch2 NRR antibodies
EP2443151A1 (en) * 2009-06-18 2012-04-25 Pfizer Inc. Anti notch-1 antibodies
WO2011009064A1 (en) * 2009-07-17 2011-01-20 The J. David Gladstone Institutes Methods of controlling cell proliferation
EP2483311B1 (en) * 2009-09-30 2016-05-18 F.Hoffmann-La Roche Ag Anti-Notch3 antagonistic antibodies for treating of a gamma-secretase inhibitor positive T-cell leukemia that does not respond to an anti-Notch1 antagonistic antibody.
US8945569B2 (en) 2009-11-19 2015-02-03 Oncomed Pharmaceuticals, Inc. Jagged-binding agents and uses thereof
CN102958534B (zh) 2010-01-13 2014-11-05 昂考梅德药品有限公司 Notch1结合剂及其使用方法
CN102933231B (zh) 2010-02-10 2015-07-29 伊缪诺金公司 Cd20抗体及其用途
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