MX2009013199A - Anticuerpos anti-notch1 nnr y sus metodos de uso. - Google Patents

Anticuerpos anti-notch1 nnr y sus metodos de uso.

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Publication number
MX2009013199A
MX2009013199A MX2009013199A MX2009013199A MX2009013199A MX 2009013199 A MX2009013199 A MX 2009013199A MX 2009013199 A MX2009013199 A MX 2009013199A MX 2009013199 A MX2009013199 A MX 2009013199A MX 2009013199 A MX2009013199 A MX 2009013199A
Authority
MX
Mexico
Prior art keywords
methods
same
notch1 nrr
nrr antibodies
antibodies
Prior art date
Application number
MX2009013199A
Other languages
English (en)
Inventor
Yan Wu
Christian W Siebel
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39735560&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009013199(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2009013199A publication Critical patent/MX2009013199A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
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    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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  • Biochemistry (AREA)
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Abstract

La invención proporciona anticuerpos anti-Notch1 NRR y composiciones que los comprenden y métodos de uso de estos anticuerpos.
MX2009013199A 2007-06-04 2008-06-03 Anticuerpos anti-notch1 nnr y sus metodos de uso. MX2009013199A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93307207P 2007-06-04 2007-06-04
US99464607P 2007-09-20 2007-09-20
PCT/US2008/007000 WO2008150525A1 (en) 2007-06-04 2008-06-03 Anti-notch1 nrr antibodies and methods using same

Publications (1)

Publication Number Publication Date
MX2009013199A true MX2009013199A (es) 2010-01-15

Family

ID=39735560

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009013199A MX2009013199A (es) 2007-06-04 2008-06-03 Anticuerpos anti-notch1 nnr y sus metodos de uso.

Country Status (29)

Country Link
US (5) US8846871B2 (es)
EP (1) EP2152748B1 (es)
JP (4) JP5623272B2 (es)
KR (2) KR20100021581A (es)
CN (1) CN101796074B (es)
AR (1) AR066846A1 (es)
BR (1) BRPI0811382A2 (es)
CA (1) CA2687866C (es)
CL (1) CL2008001634A1 (es)
CO (1) CO6150200A2 (es)
CR (2) CR11139A (es)
CY (1) CY1114690T1 (es)
DK (1) DK2152748T3 (es)
EC (1) ECSP099785A (es)
ES (1) ES2432798T3 (es)
HK (1) HK1141040A1 (es)
HR (1) HRP20131107T1 (es)
IL (3) IL202183A0 (es)
MA (1) MA31502B1 (es)
MX (1) MX2009013199A (es)
NZ (1) NZ581303A (es)
PE (1) PE20090321A1 (es)
PH (1) PH12015500550A1 (es)
PL (1) PL2152748T3 (es)
PT (1) PT2152748E (es)
RU (1) RU2476443C2 (es)
SI (1) SI2152748T1 (es)
TW (1) TWI458737B (es)
WO (1) WO2008150525A1 (es)

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US7919092B2 (en) 2006-06-13 2011-04-05 Oncomed Pharmaceuticals, Inc. Antibodies to notch receptors
AR063493A1 (es) 2006-10-19 2009-01-28 Genentech Inc Nuevos anticuerpos anti notch 3 y su uso para la deteccion y el diagnostico de enfermedades
EP2087006B1 (en) 2006-10-19 2016-06-08 Genentech, Inc. Anti-notch3 agonist antibodies and their use in the treatment of notch3-related diseases
WO2008076960A2 (en) 2006-12-18 2008-06-26 Genentech, Inc. Antagonist anti-notch3 antibodies and their use in the prevention and treatment of notch3-related diseases
JP5618544B2 (ja) 2007-01-24 2014-11-05 オンコメッドファーマシューティカルズ インコーポレイテッド 癌の診断および処置のための組成物および方法
PE20090321A1 (es) 2007-06-04 2009-04-20 Genentech Inc Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
US9132189B2 (en) 2008-07-08 2015-09-15 Oncomed Pharmaceuticals, Inc. Notch1 binding agents and methods of use thereof
ES2535614T3 (es) 2008-07-08 2015-05-13 Oncomed Pharmaceuticals, Inc. Agentes de unión a Notch y antagonistas y métodos de uso de los mismos
AR073717A1 (es) 2008-10-01 2010-11-24 Genentech Inc Anticuerpos anti-notch2 de murino y humano, y metodos de uso
WO2010146550A1 (en) * 2009-06-18 2010-12-23 Pfizer Inc. Anti notch-1 antibodies
WO2011009064A1 (en) * 2009-07-17 2011-01-20 The J. David Gladstone Institutes Methods of controlling cell proliferation
KR101782180B1 (ko) * 2009-09-30 2017-10-23 제넨테크, 인크. Ｎｏｔｃｈ3 길항제를 사용한 Ｎｏｔｃｈ1―길항제-내성 암(들)의 치료
US8945569B2 (en) 2009-11-19 2015-02-03 Oncomed Pharmaceuticals, Inc. Jagged-binding agents and uses thereof
EP2523682B1 (en) * 2010-01-13 2015-12-16 Oncomed Pharmaceuticals, Inc. Notch1 binding agents and methods of use thereof
MX341687B (es) 2010-02-10 2016-08-30 Immunogen Inc "anticuerpos cd20 y su utilización".
WO2012080891A1 (en) * 2010-12-15 2012-06-21 Rinat Neuroscience Corp. Anti-notch-1 antibodies
RU2622083C2 (ru) * 2010-12-15 2017-06-09 ВАЙЕТ ЭлЭлСи Антитела против notch1
BR112014008212A2 (pt) 2011-10-05 2017-06-13 Genentech Inc método para tratar uma condição hepática, método de indução por diferenciação hepática e método de redução de proliferação anormal do ducto biliar
EP2606884A1 (en) 2011-12-21 2013-06-26 Ecole Polytechnique Fédérale de Lausanne (EPFL) Inhibitors of notch signaling pathway and use thereof in treatment of cancers
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