KR20150118152A - 키나제 억제제로서의 퀴나졸린 - Google Patents

키나제 억제제로서의 퀴나졸린 Download PDF

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KR20150118152A
KR20150118152A KR1020157022263A KR20157022263A KR20150118152A KR 20150118152 A KR20150118152 A KR 20150118152A KR 1020157022263 A KR1020157022263 A KR 1020157022263A KR 20157022263 A KR20157022263 A KR 20157022263A KR 20150118152 A KR20150118152 A KR 20150118152A
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disease
pharmaceutically acceptable
compound
disorder
acceptable salt
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린다 엔. 카실라스
아담 케네쓰 찬리
샤오양 동
파멜라 에이. 헤일리
마이클 피. 데마티노
존 에프. 멜만
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글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드
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    • C07ORGANIC CHEMISTRY
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    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
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    • A61K31/33Heterocyclic compounds
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • C07DHETEROCYCLIC COMPOUNDS
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  • Animal Behavior & Ethology (AREA)
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  • Veterinary Medicine (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
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  • Biomedical Technology (AREA)
KR1020157022263A 2013-02-21 2014-02-19 키나제 억제제로서의 퀴나졸린 Ceased KR20150118152A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361767423P 2013-02-21 2013-02-21
US61/767,423 2013-02-21
PCT/IB2014/059094 WO2014128622A1 (en) 2013-02-21 2014-02-19 Quinazolines as kinase inhibitors

Publications (1)

Publication Number Publication Date
KR20150118152A true KR20150118152A (ko) 2015-10-21

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KR1020157022263A Ceased KR20150118152A (ko) 2013-02-21 2014-02-19 키나제 억제제로서의 퀴나졸린

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Country Link
US (1) US9650364B2 (OSRAM)
EP (1) EP2958911B1 (OSRAM)
JP (1) JP6301374B2 (OSRAM)
KR (1) KR20150118152A (OSRAM)
CN (1) CN105143208B (OSRAM)
AR (1) AR094707A1 (OSRAM)
AU (1) AU2014220300B2 (OSRAM)
BR (1) BR112015019624A2 (OSRAM)
CA (1) CA2902132C (OSRAM)
ES (1) ES2654100T3 (OSRAM)
RU (1) RU2662810C2 (OSRAM)
TW (1) TWI630203B (OSRAM)
WO (1) WO2014128622A1 (OSRAM)

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TW201425307A (zh) 2012-09-13 2014-07-01 Glaxosmithkline Llc 作為激酶抑制劑之胺基-喹啉類
TWI592417B (zh) 2012-09-13 2017-07-21 葛蘭素史克智慧財產發展有限公司 胺基喹唑啉激酶抑制劑之前藥
BR112015019624A2 (pt) 2013-02-21 2017-07-18 Glaxosmithkline Ip Dev Ltd quinazolinas como inibidores de quinase
GB201506872D0 (en) 2015-04-22 2015-06-03 Ge Oil & Gas Uk Ltd Novel compounds
GB201516243D0 (en) 2015-09-14 2015-10-28 Glaxosmithkline Ip Dev Ltd Novel compounds
CA3020792A1 (en) * 2016-04-20 2017-10-26 Glaxosmithkline Intellectual Property Development Limited Conjugates comprising ripk2 inhibitors
WO2020043122A1 (zh) * 2018-08-28 2020-03-05 南京明德新药研发有限公司 作为rip2激酶抑制剂的喹唑啉类衍生物
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US9650364B2 (en) 2017-05-16
EP2958911A1 (en) 2015-12-30
WO2014128622A1 (en) 2014-08-28
BR112015019624A2 (pt) 2017-07-18
TWI630203B (zh) 2018-07-21
CA2902132A1 (en) 2014-08-28
AR094707A1 (es) 2015-08-19
CN105143208A (zh) 2015-12-09
TW201444824A (zh) 2014-12-01
CA2902132C (en) 2020-09-22
AU2014220300A1 (en) 2015-08-06
AU2014220300B2 (en) 2016-10-13
EP2958911B1 (en) 2017-10-18
RU2662810C2 (ru) 2018-07-31
RU2015139758A (ru) 2017-03-24
ES2654100T3 (es) 2018-02-12
CN105143208B (zh) 2017-09-26
US20150361069A1 (en) 2015-12-17
JP2016509051A (ja) 2016-03-24

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