KR20150039748A - Gip 수용체 활성을 나타내는 글루카곤의 유사체들 - Google Patents

Gip 수용체 활성을 나타내는 글루카곤의 유사체들 Download PDF

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Publication number
KR20150039748A
KR20150039748A KR20157001447A KR20157001447A KR20150039748A KR 20150039748 A KR20150039748 A KR 20150039748A KR 20157001447 A KR20157001447 A KR 20157001447A KR 20157001447 A KR20157001447 A KR 20157001447A KR 20150039748 A KR20150039748 A KR 20150039748A
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KR
South Korea
Prior art keywords
amino acid
glucagon
peptide
seq
ala
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Abandoned
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KR20157001447A
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English (en)
Korean (ko)
Inventor
리차드 디. 디마치
데이비드 엘. 스마일리
콘라드 에이치. 블레이처
에릭 에이. 키타스
Original Assignee
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션
에프. 호프만-라 로슈 아게
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Application filed by 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션, 에프. 호프만-라 로슈 아게 filed Critical 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션
Publication of KR20150039748A publication Critical patent/KR20150039748A/ko
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR20157001447A 2012-06-21 2013-06-18 Gip 수용체 활성을 나타내는 글루카곤의 유사체들 Abandoned KR20150039748A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261662874P 2012-06-21 2012-06-21
US61/662,874 2012-06-21
US201361787973P 2013-03-15 2013-03-15
US61/787,973 2013-03-15
PCT/US2013/046229 WO2013192130A1 (en) 2012-06-21 2013-06-18 Analogs of glucagon exhibiting gip receptor activity

Publications (1)

Publication Number Publication Date
KR20150039748A true KR20150039748A (ko) 2015-04-13

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR20157001447A Abandoned KR20150039748A (ko) 2012-06-21 2013-06-18 Gip 수용체 활성을 나타내는 글루카곤의 유사체들

Country Status (30)

Country Link
US (2) US9868772B2 (enExample)
EP (1) EP2864350B1 (enExample)
JP (1) JP6300239B2 (enExample)
KR (1) KR20150039748A (enExample)
CN (1) CN104583233B (enExample)
AR (1) AR091478A1 (enExample)
AU (1) AU2013277372B2 (enExample)
BR (1) BR112014031671A2 (enExample)
CA (1) CA2877127A1 (enExample)
CL (1) CL2014003421A1 (enExample)
CO (1) CO7170125A2 (enExample)
CR (1) CR20150015A (enExample)
DK (1) DK2864350T3 (enExample)
EA (1) EA029025B1 (enExample)
ES (1) ES2674946T3 (enExample)
HR (1) HRP20180936T1 (enExample)
HU (1) HUE039267T2 (enExample)
IL (1) IL236386B (enExample)
MX (1) MX356000B (enExample)
MY (1) MY185217A (enExample)
PE (1) PE20150863A1 (enExample)
PH (1) PH12014502857A1 (enExample)
PL (1) PL2864350T3 (enExample)
PT (1) PT2864350T (enExample)
RS (1) RS57347B1 (enExample)
SG (1) SG11201408491SA (enExample)
SI (1) SI2864350T1 (enExample)
TR (1) TR201808818T4 (enExample)
TW (1) TWI644920B (enExample)
WO (1) WO2013192130A1 (enExample)

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CN120887972A (zh) * 2017-11-24 2025-11-04 浙江道尔生物科技有限公司 一种治疗代谢疾病的胰高血糖素类似物
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IL236386A0 (en) 2015-02-26
HRP20180936T1 (hr) 2018-12-14
US20150368310A1 (en) 2015-12-24
WO2013192130A1 (en) 2013-12-27
AU2013277372B2 (en) 2018-03-29
EA029025B1 (ru) 2018-01-31
CA2877127A1 (en) 2013-12-27
JP6300239B2 (ja) 2018-03-28
TWI644920B (zh) 2018-12-21
TW201402603A (zh) 2014-01-16
BR112014031671A2 (pt) 2018-08-07
DK2864350T3 (en) 2018-05-28
PT2864350T (pt) 2018-05-14
CR20150015A (es) 2015-04-24
CN104583233B (zh) 2018-10-23
AR091478A1 (es) 2015-02-04
MX356000B (es) 2018-05-08
MY185217A (en) 2021-04-30
IL236386B (en) 2019-09-26
TR201808818T4 (tr) 2018-07-23
CL2014003421A1 (es) 2015-05-22
EP2864350B1 (en) 2018-03-28
US20180105569A1 (en) 2018-04-19
CN104583233A (zh) 2015-04-29
EA201590065A1 (ru) 2015-07-30
US9868772B2 (en) 2018-01-16
EP2864350A1 (en) 2015-04-29
CO7170125A2 (es) 2015-01-28
JP2015528795A (ja) 2015-10-01
AU2013277372A1 (en) 2014-12-11
MX2014015556A (es) 2015-03-05
HUE039267T2 (hu) 2018-12-28
PL2864350T3 (pl) 2019-01-31
ES2674946T3 (es) 2018-07-05
RS57347B1 (sr) 2018-08-31
SI2864350T1 (en) 2018-08-31
PH12014502857A1 (en) 2015-02-23
PE20150863A1 (es) 2015-06-11
SG11201408491SA (en) 2015-01-29

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Patent event date: 20200813

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