KR20150037826A - 마이크로구조체 기반의 상처 클로저 기기 - Google Patents
마이크로구조체 기반의 상처 클로저 기기 Download PDFInfo
- Publication number
- KR20150037826A KR20150037826A KR20157000949A KR20157000949A KR20150037826A KR 20150037826 A KR20150037826 A KR 20150037826A KR 20157000949 A KR20157000949 A KR 20157000949A KR 20157000949 A KR20157000949 A KR 20157000949A KR 20150037826 A KR20150037826 A KR 20150037826A
- Authority
- KR
- South Korea
- Prior art keywords
- microstructures
- wound
- microstructure
- arrays
- array
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 473
- 206010052428 Wound Diseases 0.000 claims abstract description 471
- 238000000034 method Methods 0.000 claims abstract description 153
- 230000001681 protective effect Effects 0.000 claims abstract description 8
- 238000003491 array Methods 0.000 claims description 231
- 239000000853 adhesive Substances 0.000 claims description 103
- 230000001070 adhesive effect Effects 0.000 claims description 101
- 239000000463 material Substances 0.000 claims description 97
- 239000000017 hydrogel Substances 0.000 claims description 30
- 229920002101 Chitin Polymers 0.000 claims description 27
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims description 27
- 239000004926 polymethyl methacrylate Substances 0.000 claims description 27
- 206010061218 Inflammation Diseases 0.000 claims description 25
- 230000004054 inflammatory process Effects 0.000 claims description 25
- 229920001661 Chitosan Polymers 0.000 claims description 22
- 239000000203 mixture Substances 0.000 claims description 22
- 239000000416 hydrocolloid Substances 0.000 claims description 19
- 229910052710 silicon Inorganic materials 0.000 claims description 16
- 239000010703 silicon Substances 0.000 claims description 16
- 206010015150 Erythema Diseases 0.000 claims description 15
- -1 polyethylene Polymers 0.000 claims description 15
- 229920001296 polysiloxane Polymers 0.000 claims description 15
- 231100000321 erythema Toxicity 0.000 claims description 13
- 229920002635 polyurethane Polymers 0.000 claims description 13
- 239000004814 polyurethane Substances 0.000 claims description 13
- 239000004744 fabric Substances 0.000 claims description 11
- 239000000499 gel Substances 0.000 claims description 10
- 229920000642 polymer Polymers 0.000 claims description 9
- 238000011282 treatment Methods 0.000 claims description 9
- 206010030113 Oedema Diseases 0.000 claims description 8
- 239000004698 Polyethylene Substances 0.000 claims description 8
- 229910052751 metal Inorganic materials 0.000 claims description 8
- 239000002184 metal Substances 0.000 claims description 8
- 229920000573 polyethylene Polymers 0.000 claims description 8
- 231100000241 scar Toxicity 0.000 claims description 8
- 238000002493 microarray Methods 0.000 claims description 7
- 239000002202 Polyethylene glycol Substances 0.000 claims description 6
- 239000000648 calcium alginate Substances 0.000 claims description 6
- 235000010410 calcium alginate Nutrition 0.000 claims description 6
- 229960002681 calcium alginate Drugs 0.000 claims description 6
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 claims description 6
- 239000006071 cream Substances 0.000 claims description 6
- 239000002674 ointment Substances 0.000 claims description 6
- 230000000149 penetrating effect Effects 0.000 claims description 6
- 229920001223 polyethylene glycol Polymers 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 5
- 230000002829 reductive effect Effects 0.000 claims description 5
- 206010020751 Hypersensitivity Diseases 0.000 claims description 4
- 230000009471 action Effects 0.000 claims description 4
- 235000010443 alginic acid Nutrition 0.000 claims description 4
- 229920000615 alginic acid Polymers 0.000 claims description 4
- 239000012620 biological material Substances 0.000 claims description 4
- 239000006260 foam Substances 0.000 claims description 4
- 239000011521 glass Substances 0.000 claims description 4
- 230000000774 hypoallergenic effect Effects 0.000 claims description 4
- 150000002739 metals Chemical class 0.000 claims description 4
- 229920003023 plastic Polymers 0.000 claims description 4
- 239000004033 plastic Substances 0.000 claims description 4
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims description 3
- 229940072056 alginate Drugs 0.000 claims description 3
- 229920001222 biopolymer Polymers 0.000 claims description 3
- 239000001913 cellulose Substances 0.000 claims description 3
- 229920002678 cellulose Polymers 0.000 claims description 3
- 230000007794 irritation Effects 0.000 claims description 3
- 230000000007 visual effect Effects 0.000 claims description 3
- 229920000544 Gore-Tex Polymers 0.000 claims description 2
- 230000002745 absorbent Effects 0.000 claims description 2
- 239000002250 absorbent Substances 0.000 claims description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 2
- 230000001154 acute effect Effects 0.000 claims description 2
- 230000001464 adherent effect Effects 0.000 claims description 2
- 239000002131 composite material Substances 0.000 claims description 2
- 238000003780 insertion Methods 0.000 claims description 2
- 230000037431 insertion Effects 0.000 claims description 2
- 239000004816 latex Substances 0.000 claims description 2
- 229920000126 latex Polymers 0.000 claims description 2
- 230000009467 reduction Effects 0.000 claims description 2
- 206010039580 Scar Diseases 0.000 claims 1
- 208000030961 allergic reaction Diseases 0.000 claims 1
- 230000008021 deposition Effects 0.000 claims 1
- 238000003825 pressing Methods 0.000 claims 1
- 238000004806 packaging method and process Methods 0.000 abstract description 2
- 239000003357 wound healing promoting agent Substances 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 110
- 210000001519 tissue Anatomy 0.000 description 42
- 239000003814 drug Substances 0.000 description 28
- 239000011295 pitch Substances 0.000 description 21
- 230000000670 limiting effect Effects 0.000 description 19
- 229940079593 drug Drugs 0.000 description 18
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 15
- 230000035876 healing Effects 0.000 description 15
- 208000002193 Pain Diseases 0.000 description 11
- 238000013461 design Methods 0.000 description 11
- 210000003128 head Anatomy 0.000 description 11
- 229920002994 synthetic fiber Polymers 0.000 description 11
- 208000015181 infectious disease Diseases 0.000 description 10
- 238000004519 manufacturing process Methods 0.000 description 10
- 239000002086 nanomaterial Substances 0.000 description 10
- 230000036407 pain Effects 0.000 description 10
- 229940124597 therapeutic agent Drugs 0.000 description 10
- 210000002615 epidermis Anatomy 0.000 description 9
- 239000002121 nanofiber Substances 0.000 description 9
- 229920000728 polyester Polymers 0.000 description 9
- 239000000243 solution Substances 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 7
- 210000004207 dermis Anatomy 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 230000029663 wound healing Effects 0.000 description 7
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 6
- 230000006378 damage Effects 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 238000005530 etching Methods 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 238000000926 separation method Methods 0.000 description 6
- 208000032544 Cicatrix Diseases 0.000 description 5
- 238000005520 cutting process Methods 0.000 description 5
- 230000028709 inflammatory response Effects 0.000 description 5
- 230000037387 scars Effects 0.000 description 5
- 238000012384 transportation and delivery Methods 0.000 description 5
- 229920000742 Cotton Polymers 0.000 description 4
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 4
- 208000025865 Ulcer Diseases 0.000 description 4
- 238000004873 anchoring Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- BLFLLBZGZJTVJG-UHFFFAOYSA-N benzocaine Chemical compound CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 238000000576 coating method Methods 0.000 description 4
- 238000001035 drying Methods 0.000 description 4
- 210000003414 extremity Anatomy 0.000 description 4
- 239000003292 glue Substances 0.000 description 4
- 230000001965 increasing effect Effects 0.000 description 4
- 230000006698 induction Effects 0.000 description 4
- 208000014674 injury Diseases 0.000 description 4
- 238000005459 micromachining Methods 0.000 description 4
- 231100000252 nontoxic Toxicity 0.000 description 4
- 230000003000 nontoxic effect Effects 0.000 description 4
- 230000037368 penetrate the skin Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000001954 sterilising effect Effects 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 210000003813 thumb Anatomy 0.000 description 4
- 231100000397 ulcer Toxicity 0.000 description 4
- 201000004624 Dermatitis Diseases 0.000 description 3
- 229920005372 Plexiglas® Polymers 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 208000010668 atopic eczema Diseases 0.000 description 3
- 230000000975 bioactive effect Effects 0.000 description 3
- 230000001684 chronic effect Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 230000002354 daily effect Effects 0.000 description 3
- 239000004205 dimethyl polysiloxane Substances 0.000 description 3
- 230000002500 effect on skin Effects 0.000 description 3
- 238000011049 filling Methods 0.000 description 3
- 210000003811 finger Anatomy 0.000 description 3
- 238000003698 laser cutting Methods 0.000 description 3
- 238000001393 microlithography Methods 0.000 description 3
- 238000000465 moulding Methods 0.000 description 3
- 239000005445 natural material Substances 0.000 description 3
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 238000000820 replica moulding Methods 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 241000251468 Actinopterygii Species 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- 206010011985 Decubitus ulcer Diseases 0.000 description 2
- 206010056340 Diabetic ulcer Diseases 0.000 description 2
- 208000034693 Laceration Diseases 0.000 description 2
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 2
- 208000004221 Multiple Trauma Diseases 0.000 description 2
- 241000209094 Oryza Species 0.000 description 2
- 235000007164 Oryza sativa Nutrition 0.000 description 2
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 208000004210 Pressure Ulcer Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- 241000282887 Suidae Species 0.000 description 2
- 208000002847 Surgical Wound Diseases 0.000 description 2
- 239000004433 Thermoplastic polyurethane Substances 0.000 description 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
- 238000005299 abrasion Methods 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 239000011149 active material Substances 0.000 description 2
- 230000000172 allergic effect Effects 0.000 description 2
- 230000007815 allergy Effects 0.000 description 2
- 229940035676 analgesics Drugs 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 239000000730 antalgic agent Substances 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 238000005452 bending Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 229960005274 benzocaine Drugs 0.000 description 2
- 239000000560 biocompatible material Substances 0.000 description 2
- 230000037237 body shape Effects 0.000 description 2
- 238000005266 casting Methods 0.000 description 2
- 239000002729 catgut Substances 0.000 description 2
- 239000000769 chromic catgut Substances 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 230000000249 desinfective effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 235000012907 honey Nutrition 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 238000002357 laparoscopic surgery Methods 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 229960004194 lidocaine Drugs 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 238000002324 minimally invasive surgery Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 238000000059 patterning Methods 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 230000000704 physical effect Effects 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 239000004633 polyglycolic acid Substances 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 235000009566 rice Nutrition 0.000 description 2
- 238000002432 robotic surgery Methods 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 230000037390 scarring Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- 230000005808 skin problem Effects 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 150000003431 steroids Chemical class 0.000 description 2
- 230000008093 supporting effect Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 229920002803 thermoplastic polyurethane Polymers 0.000 description 2
- 239000003106 tissue adhesive Substances 0.000 description 2
- 229940075469 tissue adhesives Drugs 0.000 description 2
- 239000010936 titanium Substances 0.000 description 2
- 229910052719 titanium Inorganic materials 0.000 description 2
- 230000004218 vascular function Effects 0.000 description 2
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 241000938605 Crocodylia Species 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 241001514662 Leptospermum Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 229920002413 Polyhexanide Polymers 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 241000219289 Silene Species 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 206010059516 Skin toxicity Diseases 0.000 description 1
- 206010072170 Skin wound Diseases 0.000 description 1
- 206010041899 Stab wound Diseases 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 230000009692 acute damage Effects 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 229940035674 anesthetics Drugs 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 238000010420 art technique Methods 0.000 description 1
- 230000003190 augmentative effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229910052797 bismuth Inorganic materials 0.000 description 1
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000000599 controlled substance Substances 0.000 description 1
- 230000023753 dehiscence Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 229920005839 ecoflex® Polymers 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 210000000245 forearm Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000002695 general anesthesia Methods 0.000 description 1
- 239000003193 general anesthetic agent Substances 0.000 description 1
- 238000002682 general surgery Methods 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000007386 incisional biopsy Methods 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 239000012678 infectious agent Substances 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 description 1
- 229960000907 methylthioninium chloride Drugs 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000004377 microelectronic Methods 0.000 description 1
- 238000001053 micromoulding Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000001640 nerve ending Anatomy 0.000 description 1
- 239000000820 nonprescription drug Substances 0.000 description 1
- 230000037311 normal skin Effects 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 description 1
- 229920002463 poly(p-dioxanone) polymer Polymers 0.000 description 1
- 239000000622 polydioxanone Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 230000003716 rejuvenation Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 229920002781 resilin Polymers 0.000 description 1
- 108010019116 resilin Proteins 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 238000006748 scratching Methods 0.000 description 1
- 230000002393 scratching effect Effects 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 230000037075 skin appearance Effects 0.000 description 1
- 238000007390 skin biopsy Methods 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000438 skin toxicity Toxicity 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000012385 systemic delivery Methods 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 238000009941 weaving Methods 0.000 description 1
- 238000003631 wet chemical etching Methods 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- 210000000707 wrist Anatomy 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
- A61B2017/081—Tissue approximator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00655—Plasters adhesive
- A61F2013/00723—Plasters adhesive non-adhesive skin fixation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Materials For Medical Uses (AREA)
- Surgical Instruments (AREA)
- Packages (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261660561P | 2012-06-15 | 2012-06-15 | |
| US61/660,561 | 2012-06-15 | ||
| US201261710246P | 2012-10-05 | 2012-10-05 | |
| US61/710,246 | 2012-10-05 | ||
| PCT/US2013/046181 WO2013188884A1 (en) | 2012-06-15 | 2013-06-17 | Microstructure-based wound closure devices |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20150037826A true KR20150037826A (ko) | 2015-04-08 |
Family
ID=48741554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20157000949A Ceased KR20150037826A (ko) | 2012-06-15 | 2013-06-17 | 마이크로구조체 기반의 상처 클로저 기기 |
Country Status (15)
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017086661A1 (ko) * | 2015-11-16 | 2017-05-26 | 삼성전자 주식회사 | 생체신호 센싱패치 및 이를 구비한 생체신호 모니터링 장치 |
| WO2017116076A1 (ko) * | 2015-12-28 | 2017-07-06 | 주식회사 엔도더마 | 경피 흡수용 마이크로구조체 및 이의 제조방법 |
| WO2018088755A1 (ko) * | 2016-11-09 | 2018-05-17 | 김주홍 | 주름 제거용 패치 |
| WO2017176045A3 (ko) * | 2016-04-05 | 2018-08-02 | 주식회사 엘지생활건강 | 효율적인 피부 천공을 위한 마이크로니들 구조 |
| KR20190069396A (ko) * | 2016-10-18 | 2019-06-19 | 노바르티스 아게 | 표면 텍스처를 갖는 수술 기구 |
| KR20200007016A (ko) * | 2017-08-17 | 2020-01-21 | 코스메드 파마소티컬 씨오 쩜 엘티디 | 입술용 마이크로니들 어레이 |
| WO2022015071A1 (ko) * | 2020-07-17 | 2022-01-20 | 한국과학기술연구원 | 수술 전 감염 방지를 위한 마이크로니들 패치 및 마이크로니들 패치를 이용한 수술 전처리 방법 |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012236205B2 (en) | 2011-03-31 | 2016-08-25 | Brijjit Medical, Inc. | Force modulating tissue bridge |
| AU2012325922B2 (en) | 2011-10-20 | 2017-06-01 | Brijjit Medical, Inc. | Removable covering and interactive packaging |
| ES2743733T3 (es) | 2012-06-15 | 2020-02-20 | Univ Washington Through Its Center For Commercialization | Dispositivos de cierre de heridas basados en microestructuras |
| KR101703312B1 (ko) * | 2014-02-14 | 2017-02-07 | 주식회사 주빅 | 미세공구조를 포함하는 마이크로구조체-기반 약물전달체 |
| CN103800998B (zh) * | 2014-02-24 | 2016-03-30 | 苏州大学 | 一种丝素蛋白凝胶微针系统及其制备方法 |
| KR101724654B1 (ko) * | 2014-06-02 | 2017-04-12 | 주식회사 아모라이프사이언스 | 마이크로 니들 패치 및 그의 제조 방법 |
| WO2015194260A1 (ja) * | 2014-06-18 | 2015-12-23 | 凸版印刷株式会社 | マイクロニードルユニット |
| US9986988B2 (en) | 2014-11-27 | 2018-06-05 | AOD Holdings, LLC | Surgical retractor |
| US10279533B1 (en) * | 2014-12-22 | 2019-05-07 | 10X Technology, Llc | Method and apparatus for fabricating bent microneedles for use as micro-sutures in a wound closure device |
| US10792042B2 (en) | 2015-01-15 | 2020-10-06 | Ethicon, Inc. | Circular staplers having resorbable microneedles containing active agents |
| US9999759B2 (en) | 2015-01-15 | 2018-06-19 | Ethicon, Inc. | Linear staplers having resorbable microneedles containing active agents |
| WO2016208635A1 (ja) | 2015-06-23 | 2016-12-29 | 凸版印刷株式会社 | 針状体及び針状体の製造方法 |
| US10517592B2 (en) | 2015-10-29 | 2019-12-31 | Ethicon Llc | Surgical stapler buttress assembly with adhesion to wet end effector |
| WO2017083686A1 (en) * | 2015-11-11 | 2017-05-18 | BandGrip, Inc. | Bandage |
| KR20180131554A (ko) | 2016-03-01 | 2018-12-10 | 키토테크 메디컬 인코포레이티드 | 상처 봉합을 위한 마이크로 구조-기반 시스템, 장치, 및 방법 |
| US11071717B2 (en) * | 2016-07-18 | 2021-07-27 | Ana R. Olivero | Anesthetic bandage |
| US10994130B2 (en) | 2016-09-06 | 2021-05-04 | Biocircuit Technologies, Inc. | Devices and methods for repairing damage to a nerve |
| CN109862833B (zh) | 2016-10-21 | 2023-03-28 | 埃姆格公司 | 调整力的组织间桥、相关工具、套件和方法 |
| US11464956B2 (en) | 2017-02-24 | 2022-10-11 | Hisamitsu Pharmaceutical Co., Inc. | Microneedle device |
| US11337700B2 (en) | 2017-06-12 | 2022-05-24 | Terumo Kabushiki Kaisha | Subcutaneous tissue device |
| TWI645870B (zh) * | 2017-06-27 | 2019-01-01 | 韓商安道德瑪股份有限公司 | 經皮吸收用微結構體及其製造方法 |
| USD862695S1 (en) | 2017-10-20 | 2019-10-08 | Emrge, Llc | Medical tool for use in applying medical article |
| USD876641S1 (en) | 2017-10-20 | 2020-02-25 | Emrge, Llc. | Medical article for treating a wound and/or scar tissue |
| US20190125589A1 (en) * | 2017-11-02 | 2019-05-02 | BandGrip, Inc. | Bandage And Anchor For Bandages |
| JP6671616B2 (ja) * | 2017-11-02 | 2020-03-25 | コスメディ製薬株式会社 | 歯科用局所麻酔マイクロニードルアレイ |
| US11291448B2 (en) | 2017-11-15 | 2022-04-05 | BandGrip, Inc. | Mechanical tissue coupling system, applicator therefor and method of use thereof |
| US11045187B2 (en) | 2018-02-28 | 2021-06-29 | BandGrip, Inc. | Subcutaneous wound closure assembly and method of use |
| JP7487181B2 (ja) * | 2018-05-18 | 2024-05-20 | ポステック アカデミー－インダストリー ファンデーション | 経皮透過型薬物伝達パッチの製造方法 |
| CN112423829B (zh) * | 2018-05-18 | 2023-03-28 | 浦项工科大学校产学协力团 | 经皮药物递送贴剂及其制造方法 |
| EP3860470A1 (en) * | 2018-10-01 | 2021-08-11 | Kitotech Medical, Inc. | Tissue care devices including microstructures |
| EP3875141B1 (en) * | 2018-10-31 | 2022-12-14 | FUJIFILM Corporation | Micro-needle array device |
| WO2020166744A1 (ko) * | 2019-02-15 | 2020-08-20 | 주식회사 하이로닉 | 변형 구조 마이크로 니들 및 피부 드레싱용 패드를 이용한 피부 리프팅 방법 |
| EP3943020A4 (en) * | 2019-03-19 | 2022-12-14 | Jingrun (Shanghai) Medical Instruments Co., Ltd. | SURGICAL ASSISTANT DEVICE FOR SEAMLESS WOUND CLOSURE OF SKIN WOUNDS IN DEEP CONNECTIVE TISSUE OF LIMBS |
| JP7305411B2 (ja) * | 2019-04-05 | 2023-07-10 | 株式会社三共 | スロットマシン |
| WO2020247739A1 (en) * | 2019-06-07 | 2020-12-10 | Massachusetts Institute Of Technology | Manuka honey microneedle |
| US20220273926A1 (en) * | 2019-07-08 | 2022-09-01 | Board Of Regents Of The University Of Nebraska | Drug delivery using microneedle arrays |
| GB2586475A (en) * | 2019-08-20 | 2021-02-24 | Innoture Ip Ltd | Methods |
| GB2586474A (en) * | 2019-08-20 | 2021-02-24 | Innoture Ip Ltd | Method of manufacturing microstructures |
| CN114786589A (zh) | 2019-10-11 | 2022-07-22 | 埃姆格公司 | 用于在生物组织等上施加力的医疗装置 |
| EP4044932A4 (en) * | 2019-10-15 | 2024-02-21 | The Regents of the University of California | SURGICAL CLOSURE DEVICE WITH BIOLOGICAL ZIPPER |
| US11986613B2 (en) | 2020-02-19 | 2024-05-21 | Kitotech Medical, Inc. | Microstructure systems and methods for pain treatment |
| EP4106638A4 (en) * | 2020-02-19 | 2024-03-27 | Kitotech Medical, Inc. | WOUND CLOSURE DEVICE FOR WIDE TREATMENT AREAS |
| US11672635B2 (en) * | 2020-04-29 | 2023-06-13 | Bvw Holding Ag | Microstructure soft tissue graft |
| TWI888616B (zh) * | 2020-08-04 | 2025-07-01 | 瑞士商Ｂｖｗ控股公司 | 用於修補軟組織之可植入式裝置 |
| CN112716692A (zh) * | 2020-12-30 | 2021-04-30 | 无锡快邦医疗科技有限公司 | 伤口治疗用保护垫 |
| USD980434S1 (en) | 2021-01-14 | 2023-03-07 | Emrge, Llc | Medical article for treating a wound and/or scar tissue |
| US20220240935A1 (en) | 2021-01-29 | 2022-08-04 | Cheuk Yin Paul Leung | Wound closure device with wide spaced microstructures |
| EP4059445A1 (en) * | 2021-03-18 | 2022-09-21 | HoliStick Medical | Medical implant and catheter device for a medical implant |
| US11957346B2 (en) | 2022-02-18 | 2024-04-16 | Kitotech Medical, Inc. | Force modulating deep skin staples and instruments |
| CN116098669B (zh) * | 2023-03-22 | 2024-02-20 | 北京麦迪益康商贸有限公司 | 一种伤口闭合器 |
| CN117679101B (zh) * | 2024-02-04 | 2024-04-05 | 苏州大学附属第二医院 | 一种预埋式无痕皮肤缝合器 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3964482A (en) | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
| CA1006064A (en) * | 1971-12-17 | 1977-03-01 | Harrith M. Hasson | Surgical closure |
| US3926193A (en) * | 1971-12-17 | 1975-12-16 | Harrith M Hasson | Surgical closure having ease of assembly |
| US4330357A (en) * | 1980-10-23 | 1982-05-18 | Minnesota Mining And Manufacturing Company | Dispenser for liner-wound tape |
| US4430998A (en) * | 1982-06-01 | 1984-02-14 | Thoratec Laboratories Corporation | Wound closing device |
| US5047047A (en) * | 1988-10-26 | 1991-09-10 | Inbae Yoon | Wound closing device |
| US5234462A (en) * | 1991-08-29 | 1993-08-10 | Tufts University | Method and kit for accelerating the closing of open skin wounds |
| FR2690840B1 (fr) * | 1992-05-07 | 1994-08-19 | Patrick Frechet | Dispositif d'extension de tissu vivant. |
| US6503231B1 (en) | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
| JP2002517300A (ja) | 1998-06-10 | 2002-06-18 | ジョージア テック リサーチ コーポレイション | 微小針デバイスおよび製造方法ならびにそれらの使用 |
| WO2000074763A2 (en) | 1999-06-04 | 2000-12-14 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| CN101238998A (zh) * | 1999-11-15 | 2008-08-13 | 维尔克工业有限公司 | 皮肤附着件 |
| US7510566B2 (en) | 2000-05-19 | 2009-03-31 | Coapt Systems, Inc. | Multi-point tissue tension distribution device and method, a chin lift variation |
| JP2003533326A (ja) * | 2000-05-19 | 2003-11-11 | コアプト システムズ， インコーポレイテッド | 組織近置デバイスおよびその使用方法 |
| US20040260340A1 (en) * | 2000-05-19 | 2004-12-23 | Jacobs Daniel Irwin | Remotely anchored tissue fixation device and method |
| US7156862B2 (en) * | 2000-05-19 | 2007-01-02 | Coapt Systems, Inc. | Multi-point tension distribution system device and method of tissue approximation using that device to improve wound healing |
| US7172615B2 (en) * | 2000-05-19 | 2007-02-06 | Coapt Systems, Inc. | Remotely anchored tissue fixation device |
| US7537795B2 (en) * | 2000-10-26 | 2009-05-26 | Alza Corporation | Transdermal drug delivery devices having coated microprotrusions |
| WO2002064193A2 (en) | 2000-12-14 | 2002-08-22 | Georgia Tech Research Corporation | Microneedle devices and production thereof |
| US6663820B2 (en) | 2001-03-14 | 2003-12-16 | The Procter & Gamble Company | Method of manufacturing microneedle structures using soft lithography and photolithography |
| WO2004020034A2 (en) * | 2002-08-29 | 2004-03-11 | Becton Dickinson And Company | Microabrader with controlled abrasion features |
| US20040138705A1 (en) | 2003-01-09 | 2004-07-15 | Harri Heino | Surgical staple for tissue treatment |
| US7972347B2 (en) * | 2003-06-27 | 2011-07-05 | Surgical Security, Llc | Device for surgical repair, closure, and reconstruction |
| US20060093658A1 (en) | 2004-10-26 | 2006-05-04 | Gayatri Sathyan | Apparatus and method for transdermal delivery of desmopressin |
| WO2006124671A2 (en) | 2005-05-12 | 2006-11-23 | Canica Design Inc. | Dynamic tensioning system and method |
| WO2007127976A2 (en) | 2006-05-01 | 2007-11-08 | Georgia Tech Research Corporation | Particle based molding |
| KR101419730B1 (ko) | 2006-08-03 | 2014-07-15 | 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 | 반흔 및/또는 켈로이드의 치료 또는 예방을 위한 디바이스 및 붕대와 그것을 위한 방법 및 키트 |
| WO2008020633A1 (en) * | 2006-08-18 | 2008-02-21 | Toppan Printing Co., Ltd. | Microneedle and microneedle patch |
| JP2010525873A (ja) | 2007-05-01 | 2010-07-29 | ザ ブライハム アンド ウイメンズ ホスピタル， インコーポレイテッド | 創傷治癒デバイス |
| DE102009020763A1 (de) * | 2008-05-15 | 2009-11-19 | Aesculap Aktiengesellschaft | Wundverschluss |
| EP2462978A4 (en) * | 2009-08-07 | 2013-01-02 | Medrx Co Ltd | APPLICATOR DEVICE WITH A STICK HOLDER MICRONADEL |
| EP2506920B1 (en) * | 2009-12-01 | 2016-07-13 | Ecole Polytechnique Fédérale de Lausanne | Microfabricated surface neurostimulation device and method of making the same |
| RU2585138C2 (ru) | 2010-04-28 | 2016-05-27 | Кимберли-Кларк Ворлдвайд, Инк. | Медицинские устройства для доставки кирнк |
| US8851284B2 (en) * | 2011-05-18 | 2014-10-07 | Thuban, Inc. | Adhesive bandage dispensing arrangements |
| WO2012167162A2 (en) | 2011-06-03 | 2012-12-06 | University Of Washington | Methods for the production of chitin nanofibers and uses thereof |
| RU2014110970A (ru) | 2011-08-24 | 2015-09-27 | Калгон Карбон Корпорейшн | Раневая повязка, содержащая активированный уголь |
| ES2743733T3 (es) | 2012-06-15 | 2020-02-20 | Univ Washington Through Its Center For Commercialization | Dispositivos de cierre de heridas basados en microestructuras |
-
2013
- 2013-06-17 ES ES13733182T patent/ES2743733T3/es active Active
- 2013-06-17 IN IN2939KON2014 patent/IN2014KN02939A/en unknown
- 2013-06-17 MX MX2014015365A patent/MX2014015365A/es unknown
- 2013-06-17 HK HK15110283.8A patent/HK1209614A1/xx unknown
- 2013-06-17 US US14/408,244 patent/US10751050B2/en active Active
- 2013-06-17 EP EP13733182.3A patent/EP2861181B1/en active Active
- 2013-06-17 NZ NZ702677A patent/NZ702677A/en not_active IP Right Cessation
- 2013-06-17 CA CA2875227A patent/CA2875227C/en active Active
- 2013-06-17 AU AU2013273965A patent/AU2013273965B2/en not_active Ceased
- 2013-06-17 BR BR112014031438A patent/BR112014031438A2/pt not_active IP Right Cessation
- 2013-06-17 EP EP19174754.2A patent/EP3574846A1/en not_active Withdrawn
- 2013-06-17 SG SG11201408221YA patent/SG11201408221YA/en unknown
- 2013-06-17 JP JP2015517482A patent/JP6833317B2/ja active Active
- 2013-06-17 WO PCT/US2013/046181 patent/WO2013188884A1/en not_active Ceased
- 2013-06-17 KR KR20157000949A patent/KR20150037826A/ko not_active Ceased
-
2014
- 2014-12-12 ZA ZA2014/09196A patent/ZA201409196B/en unknown
-
2019
- 2019-01-10 JP JP2019002286A patent/JP6894454B2/ja active Active
-
2020
- 2020-07-15 US US16/930,217 patent/US20200345366A1/en not_active Abandoned
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017086661A1 (ko) * | 2015-11-16 | 2017-05-26 | 삼성전자 주식회사 | 생체신호 센싱패치 및 이를 구비한 생체신호 모니터링 장치 |
| WO2017116076A1 (ko) * | 2015-12-28 | 2017-07-06 | 주식회사 엔도더마 | 경피 흡수용 마이크로구조체 및 이의 제조방법 |
| RU2701361C1 (ru) * | 2015-12-28 | 2019-09-27 | Эндодерма Ко., Лтд. | Микроструктура для трансдермального введения и способ её получения |
| US11285308B2 (en) | 2015-12-28 | 2022-03-29 | Endoderma Co., Ltd. | Microstructure for transdermal absorption and method for manufacturing same |
| WO2017176045A3 (ko) * | 2016-04-05 | 2018-08-02 | 주식회사 엘지생활건강 | 효율적인 피부 천공을 위한 마이크로니들 구조 |
| KR20190069396A (ko) * | 2016-10-18 | 2019-06-19 | 노바르티스 아게 | 표면 텍스처를 갖는 수술 기구 |
| WO2018088755A1 (ko) * | 2016-11-09 | 2018-05-17 | 김주홍 | 주름 제거용 패치 |
| KR20200007016A (ko) * | 2017-08-17 | 2020-01-21 | 코스메드 파마소티컬 씨오 쩜 엘티디 | 입술용 마이크로니들 어레이 |
| WO2022015071A1 (ko) * | 2020-07-17 | 2022-01-20 | 한국과학기술연구원 | 수술 전 감염 방지를 위한 마이크로니들 패치 및 마이크로니들 패치를 이용한 수술 전처리 방법 |
| KR20220010671A (ko) * | 2020-07-17 | 2022-01-26 | 한국과학기술연구원 | 수술 전 감염 방지를 위한 마이크로니들 패치 및 마이크로니들 패치를 이용한 수술 전처리 방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201408221YA (en) | 2015-01-29 |
| HK1209614A1 (en) | 2016-04-08 |
| EP2861181B1 (en) | 2019-07-24 |
| US10751050B2 (en) | 2020-08-25 |
| IN2014KN02939A (cg-RX-API-DMAC10.html) | 2015-05-08 |
| ES2743733T3 (es) | 2020-02-20 |
| EP3574846A1 (en) | 2019-12-04 |
| JP2015523139A (ja) | 2015-08-13 |
| US20150305739A1 (en) | 2015-10-29 |
| JP6833317B2 (ja) | 2021-02-24 |
| ZA201409196B (en) | 2015-12-23 |
| CA2875227A1 (en) | 2013-12-19 |
| EP2861181A1 (en) | 2015-04-22 |
| NZ702677A (en) | 2016-05-27 |
| AU2013273965B2 (en) | 2017-11-23 |
| AU2013273965A1 (en) | 2014-12-18 |
| MX2014015365A (es) | 2015-05-11 |
| JP6894454B2 (ja) | 2021-06-30 |
| JP2019072534A (ja) | 2019-05-16 |
| US20200345366A1 (en) | 2020-11-05 |
| CA2875227C (en) | 2021-09-14 |
| BR112014031438A2 (pt) | 2017-06-27 |
| WO2013188884A1 (en) | 2013-12-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6894454B2 (ja) | 微細構造に基づく創傷閉鎖デバイス | |
| US20240366222A1 (en) | Microstructure-based systems, apparatus, and methods for wound closure | |
| JP5968909B2 (ja) | 創傷または皮膚処置デバイスおよび方法 | |
| JP6305397B2 (ja) | 個体を治療するための医療製品 | |
| JP6375363B2 (ja) | 可変の縁の幾何学形状を有する創傷または皮膚治療デバイス | |
| US12290260B2 (en) | Force modulating deep skin staples and instruments | |
| US20220240935A1 (en) | Wound closure device with wide spaced microstructures | |
| WO2017213534A1 (ru) | Способ подготовки трансплантанта, перфоратор (варианты) для его реализации и способ лечения ожоговых ран | |
| HK40002514B (en) | Microstructure-based systems, apparatus, and methods for wound closure | |
| HK40002514A (en) | Microstructure-based systems, apparatus, and methods for wound closure | |
| CN209059667U (zh) | 一种贴覆结构 | |
| RU2594446C2 (ru) | Способ подготовки трансплантата, перфоратор (варианты) для его реализации и способ лечения ожоговых ран | |
| Smart et al. | Wound dressings: surgical dressings |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20150114 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20180615 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20200227 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20200608 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20200227 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |