BR112014031438A2 - dispositivos de fechamento de feridas baseados em microestrutrura - Google Patents

dispositivos de fechamento de feridas baseados em microestrutrura

Info

Publication number
BR112014031438A2
BR112014031438A2 BR112014031438A BR112014031438A BR112014031438A2 BR 112014031438 A2 BR112014031438 A2 BR 112014031438A2 BR 112014031438 A BR112014031438 A BR 112014031438A BR 112014031438 A BR112014031438 A BR 112014031438A BR 112014031438 A2 BR112014031438 A2 BR 112014031438A2
Authority
BR
Brazil
Prior art keywords
wound
wound closure
closure devices
microstructure
devices
Prior art date
Application number
BR112014031438A
Other languages
English (en)
Inventor
Ruebel Chase
Jin Jungho
Rolandi Marco
J Berenson Ronald
Ruvolo Vittorio
Original Assignee
Univ Washington Through Its Center For Commercialization
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington Through Its Center For Commercialization filed Critical Univ Washington Through Its Center For Commercialization
Publication of BR112014031438A2 publication Critical patent/BR112014031438A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive plasters or dressings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B2017/081—Tissue approximator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00655—Plasters adhesive
    • A61F2013/00723—Plasters adhesive non-adhesive skin fixation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Abstract

resumo “dispositivos de fechamento de feridas baseados em microestrutrura” a presente invenção refere-se, geralmente, aos dispositivos de fechamento de feridas compreendendo uma ou mais microestruturas. os dispositivos são projetados de tal modo que as microestruturas são capazes de prender o tecido ou a pele ao redor de uma ferida, opcionalmente, fechar a ferida, ou fixar o tecido ou pele no local. também são fornecidos sistemas de fechamento de feridas que compreendem um ou mais dispositivos de fechamento de microestrutura de feridas juntamente com outros componentes, tais como revestimentos protetores e terapêuticos curativos de feridas. uma variedade de especificações de embalagem é divulgada como é um aparelho dispensador configurado para permitir uma simples aplicação de uma mão dos dispositivos de fechamento de feridas. métodos descritos neste documento proporcionam o fechamento de várias feridas com os dispositivos e sistemas de fechamento da ferida.
BR112014031438A 2012-06-15 2013-06-17 dispositivos de fechamento de feridas baseados em microestrutrura BR112014031438A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261660561P 2012-06-15 2012-06-15
US201261710246P 2012-10-05 2012-10-05
PCT/US2013/046181 WO2013188884A1 (en) 2012-06-15 2013-06-17 Microstructure-based wound closure devices

Publications (1)

Publication Number Publication Date
BR112014031438A2 true BR112014031438A2 (pt) 2017-06-27

Family

ID=48741554

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014031438A BR112014031438A2 (pt) 2012-06-15 2013-06-17 dispositivos de fechamento de feridas baseados em microestrutrura

Country Status (15)

Country Link
US (2) US10751050B2 (pt)
EP (2) EP2861181B1 (pt)
JP (2) JP6833317B2 (pt)
KR (1) KR20150037826A (pt)
AU (1) AU2013273965B2 (pt)
BR (1) BR112014031438A2 (pt)
CA (1) CA2875227C (pt)
ES (1) ES2743733T3 (pt)
HK (1) HK1209614A1 (pt)
IN (1) IN2014KN02939A (pt)
MX (1) MX2014015365A (pt)
NZ (1) NZ702677A (pt)
SG (1) SG11201408221YA (pt)
WO (1) WO2013188884A1 (pt)
ZA (1) ZA201409196B (pt)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013025232B1 (pt) 2011-03-31 2021-06-29 Felmont Eaves Ponte de tecido para o direcionamento de forças sobre uma superfície do tecido
KR20190107760A (ko) 2011-10-20 2019-09-20 이엠알지이, 엘엘씨. 착탈가능한 피복재
US10751050B2 (en) 2012-06-15 2020-08-25 University Of Washington Microstructure-based wound closure devices
KR101703312B1 (ko) * 2014-02-14 2017-02-07 주식회사 주빅 미세공구조를 포함하는 마이크로구조체-기반 약물전달체
CN103800998B (zh) * 2014-02-24 2016-03-30 苏州大学 一种丝素蛋白凝胶微针系统及其制备方法
KR101724654B1 (ko) * 2014-06-02 2017-04-12 주식회사 아모라이프사이언스 마이크로 니들 패치 및 그의 제조 방법
WO2015194260A1 (ja) * 2014-06-18 2015-12-23 凸版印刷株式会社 マイクロニードルユニット
US9986988B2 (en) 2014-11-27 2018-06-05 AOD Holdings, LLC Surgical retractor
US10279533B1 (en) * 2014-12-22 2019-05-07 10X Technology, Llc Method and apparatus for fabricating bent microneedles for use as micro-sutures in a wound closure device
US10792042B2 (en) 2015-01-15 2020-10-06 Ethicon, Inc. Circular staplers having resorbable microneedles containing active agents
US9999759B2 (en) 2015-01-15 2018-06-19 Ethicon, Inc. Linear staplers having resorbable microneedles containing active agents
WO2016208635A1 (ja) * 2015-06-23 2016-12-29 凸版印刷株式会社 針状体及び針状体の製造方法
US10517592B2 (en) * 2015-10-29 2019-12-31 Ethicon Llc Surgical stapler buttress assembly with adhesion to wet end effector
US10667957B2 (en) 2015-11-11 2020-06-02 BandGrip, Inc. Bandage
KR102438234B1 (ko) * 2015-11-16 2022-08-31 삼성전자주식회사 생체신호 센싱패치 및 이를 구비한 생체신호 모니터링 장치
CN108430565B (zh) * 2015-12-28 2021-07-20 (株)安道德玛 用于经皮吸收的微结构体及其制备方法
US10939912B2 (en) 2016-03-01 2021-03-09 Kitotech Medical, Inc. Microstructure-based systems, apparatus, and methods for wound closure
KR101719319B1 (ko) * 2016-04-05 2017-03-23 주식회사 엘지생활건강 효율적인 피부 천공을 위한 마이크로니들 구조
US11071717B2 (en) * 2016-07-18 2021-07-27 Ana R. Olivero Anesthetic bandage
WO2018048954A1 (en) 2016-09-06 2018-03-15 Axion Biosystems, Inc. Devices and methods for repairing damage to a nerve
TW201815356A (zh) * 2016-10-18 2018-05-01 諾華公司 具有表面紋理的外科手術器械
WO2018075879A1 (en) 2016-10-21 2018-04-26 Emrge, Llc. Force modulating tissue bridges, associated tools, kits and methods
KR20180055938A (ko) * 2016-11-09 2018-05-28 김주홍 주름 제거용 패치
KR102343698B1 (ko) * 2017-02-24 2021-12-24 히사미쓰 세이야꾸 가부시키가이샤 마이크로니들 디바이스
US20210251628A1 (en) * 2020-02-19 2021-08-19 KitoTech Medical, Inc Elastic and flexible wound closure device
US11337700B2 (en) 2017-06-12 2022-05-24 Terumo Kabushiki Kaisha Subcutaneous tissue device
TWI645870B (zh) * 2017-06-27 2019-01-01 韓商安道德瑪股份有限公司 經皮吸收用微結構體及其製造方法
EP3669929A4 (en) * 2017-08-17 2021-05-12 Cosmed Pharmaceutical Co., Ltd. MICRONADELFIELD FOR LIPS
USD862695S1 (en) 2017-10-20 2019-10-08 Emrge, Llc Medical tool for use in applying medical article
USD876641S1 (en) 2017-10-20 2020-02-25 Emrge, Llc. Medical article for treating a wound and/or scar tissue
JP6671616B2 (ja) * 2017-11-02 2020-03-25 コスメディ製薬株式会社 歯科用局所麻酔マイクロニードルアレイ
US20190125589A1 (en) * 2017-11-02 2019-05-02 BandGrip, Inc. Bandage And Anchor For Bandages
US11291448B2 (en) 2017-11-15 2022-04-05 BandGrip, Inc. Mechanical tissue coupling system, applicator therefor and method of use thereof
WO2019168926A1 (en) 2018-02-28 2019-09-06 BandGrip, Inc. Subcutaneous wound closure assembly and method of use
CN112423828B (zh) * 2018-05-18 2022-10-21 浦项工科大学校产学协力团 经皮药物递送贴剂及其制造方法
EP3795206A4 (en) * 2018-05-18 2022-01-05 Postech Academy-Industry Foundation TRANSDERMAL DRUG DISPENSING PATCH AND METHOD FOR MANUFACTURING IT
SG11202103320TA (en) 2018-10-01 2021-04-29 Kitotech Medical Inc Tissue care devices including microstructures
EP3875141B1 (en) * 2018-10-31 2022-12-14 FUJIFILM Corporation Micro-needle array device
WO2020166744A1 (ko) * 2019-02-15 2020-08-20 주식회사 하이로닉 변형 구조 마이크로 니들 및 피부 드레싱용 패드를 이용한 피부 리프팅 방법
US20220160951A1 (en) * 2019-03-19 2022-05-26 Jingrun (Shanghai) Medical Instruments Co., Ltd. Surgical auxiliary equipment for sutureless closed skin incision in deep fascia limbs
JP7305411B2 (ja) * 2019-04-05 2023-07-10 株式会社三共 スロットマシン
US11904125B2 (en) 2019-06-07 2024-02-20 Massachusetts Institute Of Technology Manuka honey microneedle
US20220273926A1 (en) * 2019-07-08 2022-09-01 Board Of Regents Of The University Of Nebraska Drug delivery using microneedle arrays
WO2021072021A1 (en) 2019-10-11 2021-04-15 Emrge, Llc Medical device for applying force on biological tissue, or the like
US20220361876A1 (en) * 2019-10-15 2022-11-17 The Regents Of The University Of California Bio-Zipper Surgical Closure Device
US11672635B2 (en) * 2020-04-29 2023-06-13 Bvw Holding Ag Microstructure soft tissue graft
KR102414580B1 (ko) * 2020-07-17 2022-07-01 한국과학기술연구원 수술 전 감염 방지를 위한 마이크로니들 패치 및 마이크로니들 패치를 이용한 수술 전처리 방법
US20220039934A1 (en) * 2020-08-04 2022-02-10 Bvw Holding Ag Microstructured soft tissue graft
CN112716692A (zh) * 2020-12-30 2021-04-30 无锡快邦医疗科技有限公司 伤口治疗用保护垫
USD980434S1 (en) 2021-01-14 2023-03-07 Emrge, Llc Medical article for treating a wound and/or scar tissue
US20220240935A1 (en) 2021-01-29 2022-08-04 Cheuk Yin Paul Leung Wound closure device with wide spaced microstructures
US11957346B2 (en) 2022-02-18 2024-04-16 Kitotech Medical, Inc. Force modulating deep skin staples and instruments
CN116098669B (zh) * 2023-03-22 2024-02-20 北京麦迪益康商贸有限公司 一种伤口闭合器
CN117679101B (zh) * 2024-02-04 2024-04-05 苏州大学附属第二医院 一种预埋式无痕皮肤缝合器

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
CA1006064A (en) * 1971-12-17 1977-03-01 Harrith M. Hasson Surgical closure
US3926193A (en) * 1971-12-17 1975-12-16 Harrith M Hasson Surgical closure having ease of assembly
US4330357A (en) * 1980-10-23 1982-05-18 Minnesota Mining And Manufacturing Company Dispenser for liner-wound tape
US4430998A (en) * 1982-06-01 1984-02-14 Thoratec Laboratories Corporation Wound closing device
US5047047A (en) * 1988-10-26 1991-09-10 Inbae Yoon Wound closing device
US5234462A (en) * 1991-08-29 1993-08-10 Tufts University Method and kit for accelerating the closing of open skin wounds
FR2690840B1 (fr) * 1992-05-07 1994-08-19 Patrick Frechet Dispositif d'extension de tissu vivant.
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
JP2002517300A (ja) 1998-06-10 2002-06-18 ジョージア テック リサーチ コーポレイション 微小針デバイスおよび製造方法ならびにそれらの使用
EP1187653B1 (en) 1999-06-04 2010-03-31 Georgia Tech Research Corporation Devices for enhanced microneedle penetration of biological barriers
WO2001036037A2 (en) * 1999-11-15 2001-05-25 Velcro Industries B.V. Skin attachment member
US20040260340A1 (en) * 2000-05-19 2004-12-23 Jacobs Daniel Irwin Remotely anchored tissue fixation device and method
US7172615B2 (en) * 2000-05-19 2007-02-06 Coapt Systems, Inc. Remotely anchored tissue fixation device
US7510566B2 (en) 2000-05-19 2009-03-31 Coapt Systems, Inc. Multi-point tissue tension distribution device and method, a chin lift variation
BRPI0110976B8 (pt) * 2000-05-19 2021-06-22 Microaire Surgical Instr Llc dispositivo de aproximação de tecidos implantável.
US7156862B2 (en) * 2000-05-19 2007-01-02 Coapt Systems, Inc. Multi-point tension distribution system device and method of tissue approximation using that device to improve wound healing
IL155583A0 (en) * 2000-10-26 2003-11-23 Alza Corp Transdermal drug delivery devices having coated microprotrusions
WO2002064193A2 (en) 2000-12-14 2002-08-22 Georgia Tech Research Corporation Microneedle devices and production thereof
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
AU2003268205B2 (en) * 2002-08-29 2010-02-18 Becton, Dickinson And Company Microabrader with controlled abrasion features
US20040138705A1 (en) 2003-01-09 2004-07-15 Harri Heino Surgical staple for tissue treatment
US7683234B2 (en) * 2006-08-03 2010-03-23 The Board Of Trustees Of The Leland Stanford Junior University Devices and bandages for the treatment or prevention of scars and/or keloids and methods and kits therefor
US7972347B2 (en) * 2003-06-27 2011-07-05 Surgical Security, Llc Device for surgical repair, closure, and reconstruction
US20060093658A1 (en) 2004-10-26 2006-05-04 Gayatri Sathyan Apparatus and method for transdermal delivery of desmopressin
CN101170950B (zh) * 2005-05-12 2010-04-21 卡尼卡设计公司 动态拉伸系统和方法
WO2007127976A2 (en) 2006-05-01 2007-11-08 Georgia Tech Research Corporation Particle based molding
JPWO2008020632A1 (ja) * 2006-08-18 2010-01-07 凸版印刷株式会社 マイクロニードル及びマイクロニードルパッチ
US8057446B2 (en) 2007-05-01 2011-11-15 The Brigham And Women's Hospital, Inc. Wound healing device
DE102009020763A1 (de) * 2008-05-15 2009-11-19 Aesculap Aktiengesellschaft Wundverschluss
US20120184916A1 (en) * 2009-08-07 2012-07-19 Medrx Co., Ltd. Applicator device of pinholder type microneedle
WO2011067297A1 (en) 2009-12-01 2011-06-09 ECOLE POLYTECHNIQUE FéDéRALE DE LAUSANNE Microfabricated neurostimulation device and methods of making and using the same
CA2797205C (en) * 2010-04-28 2019-04-16 Kimberly-Clark Worldwide, Inc. Medical devices for delivery of sirna
US8851284B2 (en) * 2011-05-18 2014-10-07 Thuban, Inc. Adhesive bandage dispensing arrangements
US20140194379A1 (en) 2011-06-03 2014-07-10 University Of Washington Through Its Center For Commercialization Methods for the production of chitin nanofibers and uses thereof
WO2013028966A2 (en) 2011-08-24 2013-02-28 Calgon Carbon Corporation Activated carbon containing wound dressing
US10751050B2 (en) 2012-06-15 2020-08-25 University Of Washington Microstructure-based wound closure devices

Also Published As

Publication number Publication date
AU2013273965B2 (en) 2017-11-23
KR20150037826A (ko) 2015-04-08
JP2015523139A (ja) 2015-08-13
CA2875227A1 (en) 2013-12-19
AU2013273965A1 (en) 2014-12-18
JP2019072534A (ja) 2019-05-16
EP2861181B1 (en) 2019-07-24
CA2875227C (en) 2021-09-14
WO2013188884A1 (en) 2013-12-19
HK1209614A1 (en) 2016-04-08
US20200345366A1 (en) 2020-11-05
ES2743733T3 (es) 2020-02-20
EP2861181A1 (en) 2015-04-22
JP6894454B2 (ja) 2021-06-30
SG11201408221YA (en) 2015-01-29
IN2014KN02939A (pt) 2015-05-08
JP6833317B2 (ja) 2021-02-24
MX2014015365A (es) 2015-05-11
ZA201409196B (en) 2015-12-23
EP3574846A1 (en) 2019-12-04
US20150305739A1 (en) 2015-10-29
US10751050B2 (en) 2020-08-25
NZ702677A (en) 2016-05-27

Similar Documents

Publication Publication Date Title
BR112014031438A2 (pt) dispositivos de fechamento de feridas baseados em microestrutrura
EP3673905A4 (en) COMPOSITION OF CANNABIDIOL AND / OR CANNABIDIVARIN AND USE OF THE COMPOSITION FOR TREATMENT OF DYSMENORRHA
BR112015019440A8 (pt) curativo regulável, kit, uso e método para fortalecimento da pele
BR112015020855A2 (pt) curativo para ferida e método de tratamento
BR112013017506A2 (pt) dispositivos e métodos de tratamento de feridas e da pele
BR112013016440A2 (pt) tira elástica, substrato elástico e método de fixação de uma tira
EP3027119A4 (en) Devices, systems and methods for providing surgical access and facilitating closure of surgical access openings
BR112015002116A2 (pt) Curativo de ferimento e método de tratamento
EP2802280A4 (en) SKIN PROTECTION FOR SUBCUTANEOUS CRYOGENE NEW MODELING FOR COSMETIC AND OTHER TREATMENTS
EP3024401A4 (en) Surgical incision and closure apparatus
BR112013010976A2 (pt) "artigos que incorporam polímero absorvente e composto ceragenin."
MX353942B (es) Sistemas para el cuidado de la piel después del procedimiento, composiciones y métodos de uso de los mismos.
EP3280402A4 (en) FORMULATION AND METHOD FOR MODULATING WOUND HEALING
BR112014014045A2 (pt) método e dispositivo para preparar os dispositivos de tratamento médico
EP2967523A4 (en) Tissue and vascular closure devices and methods of use thereof
EP3017815A4 (en) Use of naringenin in preparing drugs for preventing and/or treating abdominal aortic aneurysm
EP3072517A4 (en) Use of ginsenoside-rg3 in preparing medicine for preventing or/and treating dementia and medicine
HK1246177A1 (zh) 局部用紅細胞生成素製劑和用其提高傷口愈合的方法及其美容用途
EP3380088A4 (en) USE OF MICROARN-146A AND A CONJUGATE OF CERIUM OXIDE NANOPARTICLES TO IMPROVE HEALING AND PROMOTE TISSUE REGENERATION
EP3129043A4 (en) Polypeptide compositions with type vii collagen fibronectin type iii- like repeats and treatment methods for wound closure and healing
EP3278815A4 (en) Haemostatic and wound healing medicine
MX2016000885A (es) Empaque de proteccion de facil abertura para presentacion aseptica.
EP3525791A4 (en) USE OF CASPASE-3 INHIBITORS AND CASPASE-3 ACTIVATORS IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCER AND WOUND HEALING
BR112013015482A2 (pt) composição líquida estéril dedicada à administração na ou através da pele e/ou dos lábios, processo cosmético e sistema para tratar a pele e/ou os lábios e montagem para tratar imperfeições estéticas da pele e/ou dos lábios
EP3589279A4 (en) METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN WITH RETINOID, AND RELATED DELIVERY SYSTEMS

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15I Others concerning applications: loss of priority

Free format text: VIDE PARECER

B12F Other appeals [chapter 12.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2643 DE 31/08/2021.