KR20140035320A - 날트렉손 요법에서 약물 생체이용률의 증가 - Google Patents

날트렉손 요법에서 약물 생체이용률의 증가 Download PDF

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Publication number
KR20140035320A
KR20140035320A KR1020137017317A KR20137017317A KR20140035320A KR 20140035320 A KR20140035320 A KR 20140035320A KR 1020137017317 A KR1020137017317 A KR 1020137017317A KR 20137017317 A KR20137017317 A KR 20137017317A KR 20140035320 A KR20140035320 A KR 20140035320A
Authority
KR
South Korea
Prior art keywords
pharmaceutically acceptable
acceptable salt
naltrexone
bupropion
food
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020137017317A
Other languages
English (en)
Korean (ko)
Inventor
숀 플래나간
에두아르도 듀나예비치
Original Assignee
오렉시젠 세러퓨틱스 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46172304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20140035320(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 오렉시젠 세러퓨틱스 인크. filed Critical 오렉시젠 세러퓨틱스 인크.
Publication of KR20140035320A publication Critical patent/KR20140035320A/ko
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acoustics & Sound (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
KR1020137017317A 2010-12-03 2011-12-02 날트렉손 요법에서 약물 생체이용률의 증가 Ceased KR20140035320A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41939510P 2010-12-03 2010-12-03
US61/419,395 2010-12-03
PCT/US2011/063177 WO2012075459A1 (en) 2010-12-03 2011-12-02 Increasing drug bioavailability in naltrexone therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020187016354A Division KR101984500B1 (ko) 2010-12-03 2011-12-02 날트렉손 요법에서 약물 생체이용률의 증가

Publications (1)

Publication Number Publication Date
KR20140035320A true KR20140035320A (ko) 2014-03-21

Family

ID=46172304

Family Applications (5)

Application Number Title Priority Date Filing Date
KR1020137017317A Ceased KR20140035320A (ko) 2010-12-03 2011-12-02 날트렉손 요법에서 약물 생체이용률의 증가
KR1020217015625A Active KR102391511B1 (ko) 2010-12-03 2011-12-02 날트렉손 요법에서 약물 생체이용률의 증가
KR1020187016354A Active KR101984500B1 (ko) 2010-12-03 2011-12-02 날트렉손 요법에서 약물 생체이용률의 증가
KR1020197014576A Active KR102105857B1 (ko) 2010-12-03 2011-12-02 날트렉손 요법에서 약물 생체이용률의 증가
KR1020207011510A Active KR102258043B1 (ko) 2010-12-03 2011-12-02 날트렉손 요법에서 약물 생체이용률의 증가

Family Applications After (4)

Application Number Title Priority Date Filing Date
KR1020217015625A Active KR102391511B1 (ko) 2010-12-03 2011-12-02 날트렉손 요법에서 약물 생체이용률의 증가
KR1020187016354A Active KR101984500B1 (ko) 2010-12-03 2011-12-02 날트렉손 요법에서 약물 생체이용률의 증가
KR1020197014576A Active KR102105857B1 (ko) 2010-12-03 2011-12-02 날트렉손 요법에서 약물 생체이용률의 증가
KR1020207011510A Active KR102258043B1 (ko) 2010-12-03 2011-12-02 날트렉손 요법에서 약물 생체이용률의 증가

Country Status (27)

Country Link
US (1) US20130245056A1 (enExample)
EP (4) EP3884947B1 (enExample)
JP (5) JP6008866B2 (enExample)
KR (5) KR20140035320A (enExample)
CN (1) CN103313711A (enExample)
AR (2) AR093182A1 (enExample)
AU (2) AU2011336304B2 (enExample)
BR (1) BR112013013390A2 (enExample)
CA (2) CA2819262C (enExample)
CL (1) CL2013001564A1 (enExample)
CY (2) CY1118968T1 (enExample)
DK (3) DK3222280T3 (enExample)
ES (2) ES2866879T3 (enExample)
FI (1) FI3884947T3 (enExample)
HR (3) HRP20240115T1 (enExample)
HU (3) HUE053831T2 (enExample)
IL (3) IL226504B (enExample)
LT (3) LT2646031T (enExample)
MX (2) MX384662B (enExample)
PL (3) PL2646031T3 (enExample)
PT (3) PT2646031T (enExample)
RS (3) RS65198B1 (enExample)
RU (1) RU2640561C2 (enExample)
SI (3) SI2646031T1 (enExample)
SM (3) SMT202400038T1 (enExample)
TW (1) TWI618536B (enExample)
WO (1) WO2012075459A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2639579T3 (es) 2003-04-29 2017-10-27 Orexigen Therapeutics, Inc. Composiciones para afectar la pérdida de peso que comprende un antagonista opioide y bupropión
ES2761812T3 (es) 2005-11-22 2020-05-21 Nalpropion Pharmaceuticals Inc Composición y métodos de aumento de la sensibilidad a la insulina
WO2007089318A2 (en) * 2005-11-23 2007-08-09 Orexigen Therapeutics, Inc. Compositions and methods for reducing food cravings
CA2725930A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
CN102724878A (zh) 2010-01-11 2012-10-10 奥雷西根治疗公司 在重度抑郁症患者中提供体重减轻疗法的方法
PT2646031T (pt) * 2010-12-03 2017-05-25 Orexigen Therapeutics Inc Aumento da biodisponibilidade farmacológica numa terapêutica com naltrexona
EA201492175A1 (ru) 2012-06-06 2015-10-30 Орексиджен Терапьютикс, Инк. Способы лечения избыточного веса и ожирения
EP3253379A4 (en) * 2015-02-07 2018-10-10 Intas Pharmaceuticals Limited Pharmaceutical composition for the treatment of obesity
CN111050801B (zh) * 2017-03-28 2023-03-28 Ldn制药有限公司 用于治疗癌症的增加bcl2-相关的细胞死亡激动剂表达的药剂
EP3482751A1 (en) 2017-11-14 2019-05-15 LDN Pharma Limited Cancer treatment
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10129265A1 (de) * 2001-06-18 2003-01-02 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie
US6972291B2 (en) * 2002-07-02 2005-12-06 Bernstein Richard K Method for reducing food intake
EP1772147A2 (en) * 2003-03-17 2007-04-11 Japan Tobacco, Inc. Method for increasing the oral bioavailability of S-[2-([[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino)phenyl]-2-methylpropanethioate
ES2639579T3 (es) 2003-04-29 2017-10-27 Orexigen Therapeutics, Inc. Composiciones para afectar la pérdida de peso que comprende un antagonista opioide y bupropión
BRPI0613911A2 (pt) 2005-07-27 2011-02-22 Orexigen Therapeutics Inc composições para afetar a perda de peso
US8921344B2 (en) * 2006-11-03 2014-12-30 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
ES2761812T3 (es) 2005-11-22 2020-05-21 Nalpropion Pharmaceuticals Inc Composición y métodos de aumento de la sensibilidad a la insulina
WO2007089318A2 (en) * 2005-11-23 2007-08-09 Orexigen Therapeutics, Inc. Compositions and methods for reducing food cravings
AR058239A1 (es) 2005-11-28 2008-01-23 Orexigen Therapeutics Inc Metodos para tratar trastornos de ansiedad
US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
SI2526932T1 (sl) * 2006-06-19 2017-07-31 Alpharma Pharmaceuticals Llc Farmacevtski sestavek
KR101264789B1 (ko) 2006-06-30 2013-05-15 엘지디스플레이 주식회사 횡전계 방식 액정표시장치용 어레이 기판과 그 제조방법
CA2693992C (en) 2006-07-20 2017-01-31 Somaxon Pharmaceuticals, Inc. Methods of improving the pharmacokinetics of doxepin
TWI504419B (zh) * 2006-11-09 2015-10-21 Orexigen Therapeutics Inc 層狀醫藥調配物
KR20170077291A (ko) * 2006-11-09 2017-07-05 오렉시젠 세러퓨틱스 인크. 단위 용량 팩키지
ES2397746T3 (es) * 2007-04-11 2013-03-11 Biomarin Pharmaceutical Inc. Métodos de administración de tetrahidrobiopterina, composiciones asociadas y métodos de medición
DE102007036076A1 (de) 2007-08-01 2009-02-05 Bayer Healthcare Aktiengesellschaft Dipeptoid-Produgs und ihre Verwendung
WO2009035473A2 (en) * 2007-09-13 2009-03-19 Sanfilippo Louis C Method of treating binge eating disorder, obesity resulting from binge eating behavior and depressive disorders
CA2725930A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
PT2646031T (pt) * 2010-12-03 2017-05-25 Orexigen Therapeutics Inc Aumento da biodisponibilidade farmacológica numa terapêutica com naltrexona

Also Published As

Publication number Publication date
SMT202400038T1 (it) 2024-03-13
US20130245056A1 (en) 2013-09-19
JP2024071605A (ja) 2024-05-24
HRP20240115T1 (hr) 2024-06-07
TW201304780A (zh) 2013-02-01
RS62149B1 (sr) 2021-08-31
JP2019056004A (ja) 2019-04-11
AR124500A2 (es) 2023-04-05
RS65198B1 (sr) 2024-03-29
EP3884947B1 (en) 2023-11-15
HRP20170734T1 (hr) 2017-08-11
DK3222280T3 (da) 2021-04-19
LT2646031T (lt) 2017-06-26
BR112013013390A2 (pt) 2016-09-06
CA2819262A1 (en) 2012-06-07
DK3884947T3 (da) 2024-01-22
EP2646031B1 (en) 2017-02-22
RU2017144631A (ru) 2019-02-18
LT3884947T (lt) 2024-03-12
ES2625527T9 (es) 2018-09-25
RU2013127423A (ru) 2015-01-10
MX384662B (es) 2025-03-14
PL2646031T3 (pl) 2017-08-31
RS56014B1 (sr) 2017-09-29
PL3222280T3 (pl) 2021-11-29
KR101984500B1 (ko) 2019-05-31
KR20210063473A (ko) 2021-06-01
KR20180069089A (ko) 2018-06-22
EP4349369B1 (en) 2025-09-17
CL2013001564A1 (es) 2014-05-02
SMT201700232T1 (it) 2017-07-18
RU2017144631A3 (enExample) 2021-04-13
EP4349369A2 (en) 2024-04-10
FI3884947T3 (fi) 2024-01-30
CY1118968T1 (el) 2018-01-10
AU2017204309A1 (en) 2017-07-13
DK2646031T3 (en) 2017-05-22
CY1124331T1 (el) 2022-07-22
SI2646031T1 (sl) 2017-07-31
PT3884947T (pt) 2024-02-16
EP2646031A4 (en) 2014-04-23
HUE053831T2 (hu) 2021-07-28
KR102105857B1 (ko) 2020-05-04
JP2016210809A (ja) 2016-12-15
ES2866879T3 (es) 2021-10-20
IL279626A (en) 2021-03-01
MX356801B (es) 2018-06-13
JP6008866B2 (ja) 2016-10-19
KR20190058702A (ko) 2019-05-29
JP6456890B2 (ja) 2019-01-23
MX2013006071A (es) 2013-10-01
ES2625527T3 (es) 2017-07-19
AU2011336304B2 (en) 2017-03-30
EP2646031B9 (en) 2018-01-10
IL226504B (en) 2021-01-31
EP3884947A1 (en) 2021-09-29
HUE065852T2 (hu) 2024-06-28
CA3239386A1 (en) 2012-06-07
JP2013544290A (ja) 2013-12-12
TWI618536B (zh) 2018-03-21
WO2012075459A1 (en) 2012-06-07
EP2646031A1 (en) 2013-10-09
JP7025319B2 (ja) 2022-02-24
HUE034393T2 (en) 2018-02-28
EP4349369A3 (en) 2024-05-15
EP3222280B1 (en) 2021-01-20
KR20200044158A (ko) 2020-04-28
CN103313711A (zh) 2013-09-18
PL3884947T3 (pl) 2024-05-06
CA2819262C (en) 2024-05-28
AU2011336304A1 (en) 2013-07-11
AR093182A1 (es) 2015-05-27
SI3222280T1 (sl) 2021-11-30
IL270841A (en) 2020-01-30
PT3222280T (pt) 2021-04-22
KR102258043B1 (ko) 2021-05-28
KR102391511B1 (ko) 2022-04-26
JP2022060331A (ja) 2022-04-14
LT3222280T (lt) 2021-05-10
SI3884947T1 (sl) 2024-06-28
RU2640561C2 (ru) 2018-01-09
EP3222280A1 (en) 2017-09-27
SMT202100227T1 (it) 2021-07-12
HRP20210618T1 (hr) 2021-09-17
PT2646031T (pt) 2017-05-25

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