KR20140033127A - 스트렙토코쿠스 뉴모니애에 대한 백신 - Google Patents

스트렙토코쿠스 뉴모니애에 대한 백신 Download PDF

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Publication number
KR20140033127A
KR20140033127A KR1020137033256A KR20137033256A KR20140033127A KR 20140033127 A KR20140033127 A KR 20140033127A KR 1020137033256 A KR1020137033256 A KR 1020137033256A KR 20137033256 A KR20137033256 A KR 20137033256A KR 20140033127 A KR20140033127 A KR 20140033127A
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KR
South Korea
Prior art keywords
immunogenic composition
phtd
pneumolysin
mpl
streptococcus pneumoniae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
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KR1020137033256A
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English (en)
Korean (ko)
Inventor
필리페 데노엘
잔 풀만
빈센트 베르란트
휴즈 왈레마코
Original Assignee
글락소스미스클라인 바이오로지칼즈 에스.에이.
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Priority claimed from GBGB1108256.7A external-priority patent/GB201108256D0/en
Priority claimed from GBGB1121647.0A external-priority patent/GB201121647D0/en
Application filed by 글락소스미스클라인 바이오로지칼즈 에스.에이. filed Critical 글락소스미스클라인 바이오로지칼즈 에스.에이.
Publication of KR20140033127A publication Critical patent/KR20140033127A/ko
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
KR1020137033256A 2011-05-17 2012-05-15 스트렙토코쿠스 뉴모니애에 대한 백신 Withdrawn KR20140033127A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1108256.7 2011-05-17
GBGB1108256.7A GB201108256D0 (en) 2011-05-17 2011-05-17 Vaccine
GBGB1121647.0A GB201121647D0 (en) 2011-12-16 2011-12-16 Vaccine
GB1121647.0 2011-12-16
PCT/EP2012/058987 WO2012156391A1 (en) 2011-05-17 2012-05-15 Vaccine against streptococcus pneumoniae

Publications (1)

Publication Number Publication Date
KR20140033127A true KR20140033127A (ko) 2014-03-17

Family

ID=46062296

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020137033256A Withdrawn KR20140033127A (ko) 2011-05-17 2012-05-15 스트렙토코쿠스 뉴모니애에 대한 백신

Country Status (17)

Country Link
US (1) US20140072622A1 (enExample)
EP (1) EP2709658A1 (enExample)
JP (1) JP2014515035A (enExample)
KR (1) KR20140033127A (enExample)
CN (1) CN103533953A (enExample)
AR (1) AR086405A1 (enExample)
AU (1) AU2012257771C1 (enExample)
BR (1) BR112013029514A2 (enExample)
CA (1) CA2834834A1 (enExample)
EA (1) EA201391456A1 (enExample)
IL (1) IL229051A0 (enExample)
MX (1) MX339058B (enExample)
SG (1) SG194733A1 (enExample)
TW (1) TW201309327A (enExample)
UY (1) UY34073A (enExample)
WO (1) WO2012156391A1 (enExample)
ZA (1) ZA201308537B (enExample)

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US11844829B2 (en) * 2016-12-28 2023-12-19 Zalvac Ab Microparticles from Streptococcus pneumoniae as vaccine antigens
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CN116212012A (zh) * 2021-12-02 2023-06-06 上海泽润生物科技有限公司 复合佐剂以及包含它的疫苗制剂
WO2025229688A1 (en) * 2024-05-03 2025-11-06 Kumar Samal Shailesh Method for producing anti-phosphorylcholine antibodies and vaccine composition thereof
CN118702827B (zh) * 2024-08-27 2025-03-07 南京澄实生物医药科技有限公司 一种预防肺炎链球菌感染的融合蛋白及其应用

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TW201309327A (zh) 2013-03-01
EA201391456A1 (ru) 2014-05-30
CA2834834A1 (en) 2012-11-22
IL229051A0 (en) 2013-12-31
MX2013013444A (es) 2013-12-06
BR112013029514A2 (pt) 2019-09-24
WO2012156391A1 (en) 2012-11-22
CN103533953A (zh) 2014-01-22
ZA201308537B (en) 2015-08-26
AU2012257771C1 (en) 2015-12-03
SG194733A1 (en) 2013-12-30
EP2709658A1 (en) 2014-03-26
JP2014515035A (ja) 2014-06-26
AU2012257771A1 (en) 2013-04-04
MX339058B (es) 2016-05-09
US20140072622A1 (en) 2014-03-13
AU2012257771B2 (en) 2015-01-15
UY34073A (es) 2013-01-03
AR086405A1 (es) 2013-12-11

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