AR086405A1 - Vacuna de streptococcus pneumoniae - Google Patents
Vacuna de streptococcus pneumoniaeInfo
- Publication number
- AR086405A1 AR086405A1 ARP120101714A ARP120101714A AR086405A1 AR 086405 A1 AR086405 A1 AR 086405A1 AR P120101714 A ARP120101714 A AR P120101714A AR P120101714 A ARP120101714 A AR P120101714A AR 086405 A1 AR086405 A1 AR 086405A1
- Authority
- AR
- Argentina
- Prior art keywords
- mpl
- streptococcus pneumoniae
- monophosphoryl lipid
- immunogenic composition
- pneumoniae vaccine
- Prior art date
Links
- 229940124858 Streptococcus pneumoniae vaccine Drugs 0.000 title 1
- 230000002163 immunogen Effects 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 5
- 229940035032 monophosphoryl lipid a Drugs 0.000 abstract 5
- SNKAWJBJQDLSFF-NVKMUCNASA-N 1,2-dioleoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/CCCCCCCC SNKAWJBJQDLSFF-NVKMUCNASA-N 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 101710183389 Pneumolysin Proteins 0.000 abstract 1
- 229930182558 Sterol Natural products 0.000 abstract 1
- 241000193998 Streptococcus pneumoniae Species 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000002502 liposome Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 229920002704 polyhistidine Polymers 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 150000003432 sterols Chemical class 0.000 abstract 1
- 235000003702 sterols Nutrition 0.000 abstract 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1108256.7A GB201108256D0 (en) | 2011-05-17 | 2011-05-17 | Vaccine |
| GBGB1121647.0A GB201121647D0 (en) | 2011-12-16 | 2011-12-16 | Vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR086405A1 true AR086405A1 (es) | 2013-12-11 |
Family
ID=46062296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120101714A AR086405A1 (es) | 2011-05-17 | 2012-05-15 | Vacuna de streptococcus pneumoniae |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20140072622A1 (enExample) |
| EP (1) | EP2709658A1 (enExample) |
| JP (1) | JP2014515035A (enExample) |
| KR (1) | KR20140033127A (enExample) |
| CN (1) | CN103533953A (enExample) |
| AR (1) | AR086405A1 (enExample) |
| AU (1) | AU2012257771C1 (enExample) |
| BR (1) | BR112013029514A2 (enExample) |
| CA (1) | CA2834834A1 (enExample) |
| EA (1) | EA201391456A1 (enExample) |
| IL (1) | IL229051A0 (enExample) |
| MX (1) | MX339058B (enExample) |
| SG (1) | SG194733A1 (enExample) |
| TW (1) | TW201309327A (enExample) |
| UY (1) | UY34073A (enExample) |
| WO (1) | WO2012156391A1 (enExample) |
| ZA (1) | ZA201308537B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014060385A1 (en) * | 2012-10-17 | 2014-04-24 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
| GB201218660D0 (en) | 2012-10-17 | 2012-11-28 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| IL286493B (en) | 2015-11-06 | 2022-07-01 | Memorial Sloan Kettering Cancer Center | Triterpene saponin analogues, methods of producing same, compositions comprising same and uses thereof |
| US11844829B2 (en) * | 2016-12-28 | 2023-12-19 | Zalvac Ab | Microparticles from Streptococcus pneumoniae as vaccine antigens |
| CN110582282A (zh) | 2017-04-25 | 2019-12-17 | 佐剂技术公司 | 三萜皂苷类似物 |
| EP3630957A4 (en) * | 2017-05-23 | 2021-10-06 | Emulate, Inc. | ADVANCED LUNG MODELS |
| JP2020536946A (ja) * | 2017-10-16 | 2020-12-17 | アジュバンス・テクノロジーズ・インコーポレーテッド | トリテルペンサポニン類似物 |
| AU2020379738A1 (en) | 2019-11-05 | 2022-04-14 | Adjuvance Technologies, Inc. | Varicella zoster |
| CA3219814A1 (en) * | 2021-05-27 | 2022-12-01 | James M. Rolke | Mpla compositions and methods of use |
| CN116212012A (zh) * | 2021-12-02 | 2023-06-06 | 上海泽润生物科技有限公司 | 复合佐剂以及包含它的疫苗制剂 |
| WO2025229688A1 (en) * | 2024-05-03 | 2025-11-06 | Kumar Samal Shailesh | Method for producing anti-phosphorylcholine antibodies and vaccine composition thereof |
| CN118702827B (zh) * | 2024-08-27 | 2025-03-07 | 南京澄实生物医药科技有限公司 | 一种预防肺炎链球菌感染的融合蛋白及其应用 |
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| IT1298087B1 (it) | 1998-01-08 | 1999-12-20 | Fiderm S R L | Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni |
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| FR2802820B1 (fr) | 1999-12-27 | 2002-10-18 | Poudres & Explosifs Ste Nale | Seringue sans aiguille fonctionnant par effet tube a choc, avec maintien prealable du principe actif sur le cote |
| FR2804329B1 (fr) | 2000-02-02 | 2002-12-13 | Poudres & Explosifs Ste Nale | Seringue sans aiguille munie d'un opercule contenant le principe actif |
| FR2804869B1 (fr) | 2000-02-11 | 2002-05-17 | Poudres & Explosifs Ste Nale | Seringue sans aiguille pour l'injection d'un liquide contenu dans une ampoule pre-remplie |
| FR2805749B1 (fr) | 2000-03-01 | 2002-05-17 | Poudres & Explosifs Ste Nale | Seringue sans aiguille a deux niveaux de vitesse d'injection |
| FR2807946B1 (fr) | 2000-04-19 | 2002-06-07 | Poudres & Explosifs Ste Nale | Seringue sans aiguille fonctionnant avec un chargement pyrotechnique bicomposition |
| FR2809626B1 (fr) | 2000-05-30 | 2003-03-07 | Poudres & Explosifs Ste Nale | Seringue sans aiguille avec membrane d'isolation d'un ejecteur multiconduit |
| WO2001098334A2 (en) | 2000-06-20 | 2001-12-27 | Shire Biochem Inc. | Streptococcus antigens |
| FR2810554B1 (fr) | 2000-06-22 | 2003-05-16 | Poudres & Explosifs Ste Nale | Seringue sans aiguille munie d'un reservoir modulable |
| FR2812202B1 (fr) | 2000-07-28 | 2002-09-13 | Poudres & Explosifs Ste Nale | Seringue sans aiguille fonctionnant par mise en compression du reservoir contenant le principe actif liquide |
| GB0022742D0 (en) * | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| FR2815544B1 (fr) | 2000-10-23 | 2003-02-14 | Poudres & Explosifs Ste Nale | Seringue sans aiguille securisee a architecture compacte |
| US20030031684A1 (en) | 2001-03-30 | 2003-02-13 | Corixa Corporation | Methods for the production of 3-O-deactivated-4'-monophosphoryl lipid a (3D-MLA) |
| CN100443116C (zh) | 2002-11-07 | 2008-12-17 | 新纳几美国公司 | 治疗或预防肺炎球菌感染的组合物及其用途 |
| MXPA05009579A (es) | 2003-03-13 | 2005-11-17 | Glaxosmithkline Biolog Sa | Proceso de purificacion para citolisina bacteriana. |
| WO2005076696A2 (en) | 2004-02-13 | 2005-08-25 | Sanofi Pasteur Limited | Pneumolysin derivatives |
| GB0410220D0 (en) | 2004-05-07 | 2004-06-09 | Kirkham Lea Ann | Mutant pneumolysin proteins |
| GB0421083D0 (en) | 2004-09-22 | 2004-10-27 | Glaxosmithkline Biolog Sa | Purification process |
| GB0525321D0 (en) * | 2005-12-13 | 2006-01-18 | Glaxosmithkline Biolog Sa | Novel compositions |
| TWI457133B (zh) * | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| JP5792920B2 (ja) | 2005-12-22 | 2015-10-14 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| EP2468300B1 (en) * | 2006-09-26 | 2017-12-20 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| CA2694466A1 (en) | 2007-07-23 | 2009-01-29 | Sanofi Pasteur Limited | Immunogenic polypeptides and monoclonal antibodies |
| JP2010534622A (ja) | 2007-07-26 | 2010-11-11 | サノフィ パストゥール リミテッド | 抗原−アジュバント組成物および方法 |
| GB0724357D0 (en) | 2007-12-14 | 2008-01-23 | Glaxosmithkline Biolog Sa | Method for preparing protein conjugates |
| ES2331863B1 (es) | 2008-07-15 | 2010-10-27 | Consejo Superior De Investigaciones Cientificas (Csic) | Bacterias y productos derivados para fortalecer las defensas y reducir el riesgo de enfermedad. |
| CN106008679A (zh) | 2008-12-24 | 2016-10-12 | 荷兰王国卫生福利和运动部国家公共卫生和环境研究所 | 修饰的肺炎链球菌溶血素(ply)多肽 |
| WO2010109325A2 (en) | 2009-03-24 | 2010-09-30 | Novartis Ag | Combinations including pneumococcal serotype 14 saccharide |
| ES2531115T3 (es) | 2009-06-01 | 2015-03-10 | Novartis Ag | Combinaciones de clados de RrgB neumocócicos |
| KR20120107121A (ko) | 2009-12-22 | 2012-09-28 | 사노피 파스퇴르 리미티드 | 면역원성 조성물 |
-
2012
- 2012-05-15 KR KR1020137033256A patent/KR20140033127A/ko not_active Withdrawn
- 2012-05-15 MX MX2013013444A patent/MX339058B/es active IP Right Grant
- 2012-05-15 UY UY0001034073A patent/UY34073A/es not_active Application Discontinuation
- 2012-05-15 AU AU2012257771A patent/AU2012257771C1/en not_active Ceased
- 2012-05-15 US US14/118,387 patent/US20140072622A1/en not_active Abandoned
- 2012-05-15 CN CN201280023465.8A patent/CN103533953A/zh active Pending
- 2012-05-15 TW TW101117268A patent/TW201309327A/zh unknown
- 2012-05-15 SG SG2013080973A patent/SG194733A1/en unknown
- 2012-05-15 EP EP12720518.5A patent/EP2709658A1/en not_active Ceased
- 2012-05-15 AR ARP120101714A patent/AR086405A1/es unknown
- 2012-05-15 JP JP2014510771A patent/JP2014515035A/ja not_active Ceased
- 2012-05-15 WO PCT/EP2012/058987 patent/WO2012156391A1/en not_active Ceased
- 2012-05-15 EA EA201391456A patent/EA201391456A1/ru unknown
- 2012-05-15 BR BR112013029514A patent/BR112013029514A2/pt not_active IP Right Cessation
- 2012-05-15 CA CA2834834A patent/CA2834834A1/en not_active Abandoned
-
2013
- 2013-10-24 IL IL229051A patent/IL229051A0/en unknown
- 2013-11-13 ZA ZA2013/08537A patent/ZA201308537B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL229051A0 (en) | 2013-12-31 |
| BR112013029514A2 (pt) | 2019-09-24 |
| UY34073A (es) | 2013-01-03 |
| US20140072622A1 (en) | 2014-03-13 |
| JP2014515035A (ja) | 2014-06-26 |
| KR20140033127A (ko) | 2014-03-17 |
| SG194733A1 (en) | 2013-12-30 |
| ZA201308537B (en) | 2015-08-26 |
| AU2012257771B2 (en) | 2015-01-15 |
| EA201391456A1 (ru) | 2014-05-30 |
| MX339058B (es) | 2016-05-09 |
| AU2012257771A1 (en) | 2013-04-04 |
| CN103533953A (zh) | 2014-01-22 |
| EP2709658A1 (en) | 2014-03-26 |
| WO2012156391A1 (en) | 2012-11-22 |
| CA2834834A1 (en) | 2012-11-22 |
| MX2013013444A (es) | 2013-12-06 |
| AU2012257771C1 (en) | 2015-12-03 |
| TW201309327A (zh) | 2013-03-01 |
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