KR20130093084A - 단백질 Ａ(ＳｐＡ) 변이체와 관련된 조성물 및 방법 - Google Patents

단백질 Ａ(ＳｐＡ) 변이체와 관련된 조성물 및 방법 Download PDF

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Publication number
KR20130093084A
KR20130093084A KR1020137002673A KR20137002673A KR20130093084A KR 20130093084 A KR20130093084 A KR 20130093084A KR 1020137002673 A KR1020137002673 A KR 1020137002673A KR 20137002673 A KR20137002673 A KR 20137002673A KR 20130093084 A KR20130093084 A KR 20130093084A
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South Korea
Prior art keywords
protein
spa
staphylococcus
amino acid
composition
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Abandoned
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KR1020137002673A
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English (en)
Korean (ko)
Inventor
올라프 슈니윈드
앨리스 지. 청
도미니크 엠. 미샤카스
환 김
Original Assignee
더 유니버시티 오브 시카고
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Publication of KR20130093084A publication Critical patent/KR20130093084A/ko
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020137002673A 2010-07-02 2011-07-01 단백질 Ａ(ＳｐＡ) 변이체와 관련된 조성물 및 방법 Abandoned KR20130093084A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US36121810P 2010-07-02 2010-07-02
US61/361,218 2010-07-02
US37072510P 2010-08-04 2010-08-04
US61/370,725 2010-08-04
PCT/US2011/042845 WO2012003474A2 (en) 2010-07-02 2011-07-01 Compositions and methods related to protein a (spa) variants

Publications (1)

Publication Number Publication Date
KR20130093084A true KR20130093084A (ko) 2013-08-21

Family

ID=45402686

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020137002673A Abandoned KR20130093084A (ko) 2010-07-02 2011-07-01 단백질 Ａ(ＳｐＡ) 변이체와 관련된 조성물 및 방법

Country Status (12)

Country Link
US (8) US8821894B2 (cg-RX-API-DMAC7.html)
EP (1) EP2588120B1 (cg-RX-API-DMAC7.html)
JP (1) JP6002128B2 (cg-RX-API-DMAC7.html)
KR (1) KR20130093084A (cg-RX-API-DMAC7.html)
CN (1) CN103037885B (cg-RX-API-DMAC7.html)
AU (1) AU2011274367B2 (cg-RX-API-DMAC7.html)
BR (1) BR112013000097B1 (cg-RX-API-DMAC7.html)
CA (1) CA2803298C (cg-RX-API-DMAC7.html)
ES (1) ES2655701T3 (cg-RX-API-DMAC7.html)
SG (1) SG186290A1 (cg-RX-API-DMAC7.html)
WO (1) WO2012003474A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201209561B (cg-RX-API-DMAC7.html)

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CA2803298C (en) 2010-07-02 2020-07-14 The University Of Chicago Compositions and methods related to protein a (spa) variants
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JP5793194B2 (ja) * 2010-09-09 2015-10-14 ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ 感染防御ブドウ球菌抗原が関与する方法および組成物
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EP3101027B1 (en) * 2013-12-09 2018-11-07 Olymvax Biopharmaceuticals Inc. Staphylococcus aureus spa5 mutant, composition comprising mutant and preparation method and use thereof
CN105407905B (zh) * 2014-01-03 2020-03-03 生物辐射实验室股份有限公司 蛋白a洗脱产物中杂质的去除
JP6705806B2 (ja) * 2015-03-26 2020-06-03 Jsr株式会社 イムノグロブリン結合タンパク質およびそれを用いたアフィニティー担体
US11214600B2 (en) * 2016-02-12 2022-01-04 The University Of Chicago Compositions and methods related to antibodies that neutralize coagulase activity during Staphylococcus aureus disease
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
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GB201802339D0 (en) * 2018-02-13 2018-03-28 Glaxosmithkline Biologicals Sa Immunogenic composition
KR20220025724A (ko) * 2019-05-14 2022-03-03 더 유니버서티 오브 시카고 스타필로코커스 단백질 Ａ(ＳｐＡ) 변이체를 포함하는 방법 및 조성물
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