KR20120066688A - 경점막 약물 전달 시스템 - Google Patents

경점막 약물 전달 시스템 Download PDF

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Publication number
KR20120066688A
KR20120066688A KR1020127014734A KR20127014734A KR20120066688A KR 20120066688 A KR20120066688 A KR 20120066688A KR 1020127014734 A KR1020127014734 A KR 1020127014734A KR 20127014734 A KR20127014734 A KR 20127014734A KR 20120066688 A KR20120066688 A KR 20120066688A
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KR
South Korea
Prior art keywords
acid
agents
tablet
ionizable
sublingual
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Withdrawn
Application number
KR1020127014734A
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English (en)
Korean (ko)
Inventor
존 에이. 맥카티
Original Assignee
파마슈티칼 프로덕션스, 인크.
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Application filed by 파마슈티칼 프로덕션스, 인크. filed Critical 파마슈티칼 프로덕션스, 인크.
Publication of KR20120066688A publication Critical patent/KR20120066688A/ko
Withdrawn legal-status Critical Current

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
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    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
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    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Addiction (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020127014734A 2003-02-24 2004-02-24 경점막 약물 전달 시스템 Withdrawn KR20120066688A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44964703P 2003-02-24 2003-02-24
US60/449,647 2003-02-24

Related Parent Applications (1)

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KR1020057015592A Division KR101170844B1 (ko) 2003-02-24 2004-02-24 경점막 약물 전달 시스템

Publications (1)

Publication Number Publication Date
KR20120066688A true KR20120066688A (ko) 2012-06-22

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ID=32927543

Family Applications (2)

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KR1020127014734A Withdrawn KR20120066688A (ko) 2003-02-24 2004-02-24 경점막 약물 전달 시스템
KR1020057015592A Expired - Fee Related KR101170844B1 (ko) 2003-02-24 2004-02-24 경점막 약물 전달 시스템

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Country Link
US (3) US8992974B2 (https=)
EP (3) EP2343045A3 (https=)
JP (2) JP5475215B2 (https=)
KR (2) KR20120066688A (https=)
CN (1) CN1777411B (https=)
CA (1) CA2516816C (https=)
DK (1) DK1599186T3 (https=)
ES (1) ES2414084T3 (https=)
IL (1) IL170174A (https=)
MX (1) MXPA05008918A (https=)
RU (1) RU2342953C2 (https=)
WO (1) WO2004075877A1 (https=)

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