KR20100076947A - 인간화 노치 융합 단백질 조성물 및 치료방법 - Google Patents
인간화 노치 융합 단백질 조성물 및 치료방법 Download PDFInfo
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- KR20100076947A KR20100076947A KR20107006041A KR20107006041A KR20100076947A KR 20100076947 A KR20100076947 A KR 20100076947A KR 20107006041 A KR20107006041 A KR 20107006041A KR 20107006041 A KR20107006041 A KR 20107006041A KR 20100076947 A KR20100076947 A KR 20100076947A
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| CN102112490B (zh) | 2008-07-08 | 2014-10-22 | 昂考梅德药品有限公司 | Notch1受体结合剂和其使用方法 |
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| US12065479B2 (en) | 2017-11-16 | 2024-08-20 | The Regents Of The University Of California | Force sensor cleavage domain containing chimeric polypeptides and methods of use thereof |
| CN108753833B (zh) * | 2018-05-28 | 2021-12-03 | 上海海洋大学 | 斑马鱼notch3基因突变体的制备方法 |
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| CN109467598B (zh) * | 2018-11-28 | 2021-11-09 | 生命谷（海南）生物科技股份有限公司 | 肿瘤相关基因notch1突变短肽及其应用 |
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| CN112961250B (zh) * | 2021-03-01 | 2023-06-06 | 长春金赛药业有限责任公司 | 抗体融合蛋白及其应用 |
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| GB9623236D0 (en) * | 1996-11-07 | 1997-01-08 | Imperial College | Notch |
| US6379925B1 (en) * | 1997-06-18 | 2002-04-30 | The Trustees Of Columbia University In The City Of New York | Angiogenic modulation by notch signal transduction |
| US6703221B1 (en) | 1999-08-19 | 2004-03-09 | Chiron Corporation | Notch receptor ligands and uses thereof |
| GB9927328D0 (en) | 1999-11-18 | 2000-01-12 | Lorantis Ltd | Immunotherapy |
| US6689744B2 (en) | 2000-09-22 | 2004-02-10 | Genentech, Inc. | Notch receptor agonists and uses |
| WO2003042246A2 (en) | 2001-11-14 | 2003-05-22 | Lorantis Limited | Inhibitors of the notch signalling pathway for use in the treatment of cancer |
| AU2003226537A1 (en) * | 2002-04-05 | 2003-10-27 | Lorantis Limited | Modulators of the notch signalling pathway and uses thereof in medical treatment |
| WO2004013179A1 (en) * | 2002-08-03 | 2004-02-12 | Lorantis Limited | Conjugate of notch signalling pathway modulators and their use in medical treatment |
| AU2003267563A1 (en) | 2002-09-10 | 2004-04-30 | Lorantis Limited | Pharmaceutical composition and medical treatments comprising notch ligand proteins |
| WO2005111072A2 (en) * | 2004-04-29 | 2005-11-24 | The Trustees Of Columbia University In The City Of New York | Notch-based fusion proteins and uses thereof |
| US20060134121A1 (en) * | 2004-10-29 | 2006-06-22 | Gavin Thurston | DII4 antagonists, assays, and therapeutic methods thereof |
| WO2006047878A1 (en) | 2004-11-03 | 2006-05-11 | British Columbia Cancer Agency Branch | Cancer therapeutics and methods for their use |
| CN101277672A (zh) * | 2005-07-29 | 2008-10-01 | 通用医疗公司 | 用于减少皮肤损伤的方法和组合物 |
| RU2461569C2 (ru) | 2006-10-19 | 2012-09-20 | Дженентек, Инк. | Агонистические антитела против notch3 и их применение для лечения notch3-ассоциированных заболеваний |
| WO2010021729A2 (en) | 2008-08-22 | 2010-02-25 | The Trustees Of Columbia University In The City Of New York | Human notch3 based fusion proteins as decoy inhibitors of notch3 signaling |
| TW201329105A (zh) * | 2011-10-04 | 2013-07-16 | Thr Trustees Of Columbia University In The City Of New York | 人類ｎｏｔｃｈ１引誘物 |
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- 2008-08-22 AU AU2008289462A patent/AU2008289462B2/en not_active Ceased
- 2008-08-22 CA CA 2697262 patent/CA2697262A1/en not_active Abandoned
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- 2008-08-22 NZ NZ583649A patent/NZ583649A/en not_active IP Right Cessation
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2010
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2012
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2015
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- 2015-09-03 US US14/844,642 patent/US20160115217A1/en not_active Abandoned
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| NZ618129A (en) | 2015-05-29 |
| ZA201001427B (en) | 2011-05-25 |
| IL204111A (en) | 2015-08-31 |
| CA2697262A1 (en) | 2009-02-26 |
| US20160115217A1 (en) | 2016-04-28 |
| JP2016040245A (ja) | 2016-03-24 |
| EP2193143A4 (en) | 2012-01-25 |
| IL220723A0 (en) | 2012-08-30 |
| AU2008289462B2 (en) | 2014-01-23 |
| US9127085B2 (en) | 2015-09-08 |
| AU2008289462A1 (en) | 2009-02-26 |
| CN101883786A (zh) | 2010-11-10 |
| WO2009025867A2 (en) | 2009-02-26 |
| JP2010536855A (ja) | 2010-12-02 |
| NZ600171A (en) | 2014-01-31 |
| MX2010002053A (es) | 2010-07-28 |
| NZ583649A (en) | 2012-06-29 |
| RU2010110812A (ru) | 2011-09-27 |
| EP2193143B1 (en) | 2016-06-08 |
| WO2009025867A3 (en) | 2009-12-30 |
| EP2193143A2 (en) | 2010-06-09 |
| US20110008342A1 (en) | 2011-01-13 |
| BRPI0815291A2 (pt) | 2015-02-03 |
| RU2532830C2 (ru) | 2014-11-10 |
| SG183763A1 (en) | 2012-09-27 |
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