KR20080059265A - 포유동물의 위장관으로부터 칼륨 이온을 선택적으로제거하기 위한 방법 및 조성물 - Google Patents
포유동물의 위장관으로부터 칼륨 이온을 선택적으로제거하기 위한 방법 및 조성물Info
- Publication number
- KR20080059265A KR20080059265A KR1020087010227A KR20087010227A KR20080059265A KR 20080059265 A KR20080059265 A KR 20080059265A KR 1020087010227 A KR1020087010227 A KR 1020087010227A KR 20087010227 A KR20087010227 A KR 20087010227A KR 20080059265 A KR20080059265 A KR 20080059265A
- Authority
- KR
- South Korea
- Prior art keywords
- core
- shell
- polymer
- hours
- potassium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 238000000034 method Methods 0.000 title claims abstract description 112
- 229910001414 potassium ion Inorganic materials 0.000 title claims description 136
- 210000001035 gastrointestinal tract Anatomy 0.000 title claims description 87
- 241000124008 Mammalia Species 0.000 title claims description 39
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 title claims description 18
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- 230000027455 binding Effects 0.000 claims abstract description 278
- 239000011591 potassium Substances 0.000 claims abstract description 147
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims abstract description 144
- 229910052700 potassium Inorganic materials 0.000 claims abstract description 144
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- 239000011777 magnesium Substances 0.000 claims description 72
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- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims 4
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| DE (1) | DE112006002618T5 (enExample) |
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| EP1732523B9 (en) * | 2004-03-30 | 2010-06-02 | Relypsa, Inc. | Potassium binding polymers and uses thereof |
| KR20080059265A (ko) | 2005-09-30 | 2008-06-26 | 일립사, 인코포레이티드 | 포유동물의 위장관으로부터 칼륨 이온을 선택적으로제거하기 위한 방법 및 조성물 |
| KR102150184B1 (ko) * | 2008-08-22 | 2020-08-31 | 리립사, 인크. | 가교결합된 양이온교환 폴리머, 조성물 및 고칼륨혈증 치료 용도 |
| US20100111892A1 (en) * | 2008-08-22 | 2010-05-06 | Relypsa, Inc. | Crosslinked polyfluoroacrylic acid and processes for the preparation thereof |
| AU2013204879B2 (en) * | 2008-08-22 | 2015-10-29 | Vifor (International) Ltd. | Crosslinked cation exchange polymers, compositions and use in treating hyperkalemia |
| US8337824B2 (en) * | 2008-08-22 | 2012-12-25 | Relypsa, Inc. | Linear polyol stabilized polyfluoroacrylate compositions |
| WO2010022381A1 (en) * | 2008-08-22 | 2010-02-25 | Relypsa, Inc. | Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties |
| EP2470290B1 (en) | 2009-08-26 | 2019-07-24 | Evoqua Water Technologies Pte. Ltd. | Ion exchange membranes |
| US9314523B2 (en) | 2010-09-21 | 2016-04-19 | Elwha Llc | Ingestible salt grabber |
| CN106110898B (zh) * | 2010-10-15 | 2019-03-22 | 懿华水处理技术有限责任公司 | 阴离子交换膜及制造方法 |
| CN103237591B (zh) | 2010-10-15 | 2016-04-13 | 伊沃夸水处理技术有限责任公司 | 制备用于制造阳离子交换膜的单体溶液的方法 |
| PH12013501762B1 (en) | 2011-02-11 | 2019-02-06 | Zs Pharma Inc | Microporous zirconium silicate for the treatment of hyperkalemia |
| CN103703033A (zh) | 2011-06-27 | 2014-04-02 | 瑞立普萨公司 | 用于将聚合酯转化为聚合酸的方法 |
| EP2570183A1 (en) * | 2011-09-15 | 2013-03-20 | InstrAction GmbH | Sorbent comprising on its surface an aliphatic unit for the purification of organic molecules |
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-
2006
- 2006-10-02 KR KR1020087010227A patent/KR20080059265A/ko not_active Ceased
- 2006-10-02 AU AU2006299449A patent/AU2006299449B2/en not_active Ceased
- 2006-10-02 BR BRPI0616604-0A patent/BRPI0616604A2/pt not_active IP Right Cessation
- 2006-10-02 CA CA2624170A patent/CA2624170C/en not_active Expired - Fee Related
- 2006-10-02 US US12/088,625 patent/US8617609B2/en not_active Expired - Fee Related
- 2006-10-02 JP JP2008533776A patent/JP2009510126A/ja active Pending
- 2006-10-02 CN CNA2006800442481A patent/CN101316601A/zh active Pending
- 2006-10-02 WO PCT/US2006/038602 patent/WO2007041569A1/en not_active Ceased
- 2006-10-02 GB GB0806896A patent/GB2446077B/en not_active Expired - Fee Related
- 2006-10-02 EP EP06816101A patent/EP1928476A1/en not_active Withdrawn
- 2006-10-02 DE DE112006002618T patent/DE112006002618T5/de not_active Withdrawn
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2016
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2018
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| Publication number | Publication date |
|---|---|
| BRPI0616604A2 (pt) | 2012-12-25 |
| EP1928476A1 (en) | 2008-06-11 |
| CN101316601A (zh) | 2008-12-03 |
| US20090155370A1 (en) | 2009-06-18 |
| CA2624170C (en) | 2014-02-25 |
| US9301974B2 (en) | 2016-04-05 |
| US20160193247A1 (en) | 2016-07-07 |
| CA2624170A1 (en) | 2007-04-12 |
| US20180133244A1 (en) | 2018-05-17 |
| US20130259949A1 (en) | 2013-10-03 |
| AU2006299449A1 (en) | 2007-04-12 |
| US10058567B2 (en) | 2018-08-28 |
| GB2446077B (en) | 2010-10-13 |
| JP2009510126A (ja) | 2009-03-12 |
| GB2446077A (en) | 2008-07-30 |
| WO2007041569A1 (en) | 2007-04-12 |
| US10905711B2 (en) | 2021-02-02 |
| GB0806896D0 (en) | 2008-05-21 |
| US8617609B2 (en) | 2013-12-31 |
| DE112006002618T5 (de) | 2008-08-28 |
| AU2006299449B2 (en) | 2013-07-04 |
| US20140044804A1 (en) | 2014-02-13 |
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