KR20070085407A - 단백질 키나아제의 억제제로서 유용한 트리아졸 - Google Patents
단백질 키나아제의 억제제로서 유용한 트리아졸 Download PDFInfo
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- KR20070085407A KR20070085407A KR1020077011405A KR20077011405A KR20070085407A KR 20070085407 A KR20070085407 A KR 20070085407A KR 1020077011405 A KR1020077011405 A KR 1020077011405A KR 20077011405 A KR20077011405 A KR 20077011405A KR 20070085407 A KR20070085407 A KR 20070085407A
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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| US62127004P | 2004-10-21 | 2004-10-21 | |
| US60/621,270 | 2004-10-21 |
Publications (1)
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| KR20070085407A true KR20070085407A (ko) | 2007-08-27 |
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Family Applications (1)
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| JP (1) | JP5085330B2 (https=) |
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| CA2673965A1 (en) | 2006-12-28 | 2008-07-10 | Taisho Pharmaceutical Co., Ltd. | Pyrazolopyrimidine compound |
| CA2710046C (en) | 2006-12-29 | 2016-02-09 | Rigel Pharmaceuticals, Inc. | N3-heteroaryl substituted triazoles and n5-heteroaryl substituted triazoles useful as axl inhibitors |
| AU2014200824B2 (en) * | 2006-12-29 | 2016-12-15 | Rigel Pharmaceuticals, Inc. | Substituted triazoles useful as Axl inhibitors |
| WO2008083353A1 (en) | 2006-12-29 | 2008-07-10 | Rigel Pharmaceuticals, Inc. | Bicyclic aryl and bicyclic heteroaryl substituted triazoles useful as axl inhibitors |
| AU2016259396B2 (en) * | 2006-12-29 | 2018-11-08 | Rigel Pharmaceuticals, Inc. | Substituted triazoles useful as Axl inhibitors |
| US8012965B2 (en) | 2006-12-29 | 2011-09-06 | Rigel Pharmaceuticals, Inc. | Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors |
| JP2010514810A (ja) * | 2006-12-29 | 2010-05-06 | ライジェル ファーマシューティカルズ， インコーポレイテッド | Ａｘｌインヒビターとして有用な置換トリアゾール |
| JO2784B1 (en) | 2007-10-18 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | 5,3,1 - Triazole substitute derivative |
| CA2697974C (en) * | 2007-10-18 | 2015-06-30 | Janssen Pharmaceutica Nv | Trisubstituted 1,2,4-triazoles |
| WO2009115547A1 (en) | 2008-03-19 | 2009-09-24 | Janssen Pharmaceutica Nv | Trisubstituted 1, 2, 4 -triazoiies as nicotinic acetylcholine receptor modulators |
| AR071763A1 (es) | 2008-05-09 | 2010-07-14 | Janssen Pharmaceutica Nv | Pirazoles trisustituidos, composiciones farmaceuticas que los contienen, y usos de los mismos en el tratamiento de trastornos neurologicos y psiquiatricos |
| JP5613156B2 (ja) | 2008-07-09 | 2014-10-22 | ライジェル ファーマシューティカルズ， インコーポレイテッド | Ａｘｌ阻害剤として有用な架橋二環ヘテロアリール置換トリアゾール |
| JP5603881B2 (ja) | 2009-01-15 | 2014-10-08 | ライジェル ファーマシューティカルズ， インコーポレイテッド | プロテインキナーゼｃ阻害剤とその使用 |
| PL2387395T3 (pl) | 2009-01-16 | 2015-03-31 | Rigel Pharmaceuticals Inc | Inhibitory Axl do zastosowania w terapii skojarzonej do zapobiegania, leczenia lub postępowania z nowotworem przerzutowym |
| EP2569294B1 (en) | 2010-05-11 | 2015-03-11 | Sanofi | Substituted n-heteroaryl bipyrrolidine carboxamides, preparation and therapeutic use thereof |
| AR081498A1 (es) | 2010-05-11 | 2012-09-19 | Sanofi Aventis | Derivados de n-alquil -y n-acil-tetrahidroisoquinolina sustituidos, preparacion y su uso terapeutico de los mismos |
| EP2569297A1 (en) | 2010-05-11 | 2013-03-20 | Sanofi | Substituted n-heterocycloalkyl bipyrrolidinylphenyl amide derivatives, preparation and therapeutic use thereof |
| WO2011143148A1 (en) | 2010-05-11 | 2011-11-17 | Sanofi | Substituted n-heteroaryl spirolactam bipyrrolidines, preparation and therapeutic use thereof |
| EP2569280B1 (en) | 2010-05-11 | 2015-02-25 | Sanofi | Substituted phenyl cycloalkyl pyrrolidine (piperidine) spirolactams and amides, preparation and therapeutic use thereof |
| TW201206444A (en) | 2010-05-11 | 2012-02-16 | Sanofi Aventis | Substituted N-heteroaryl tetrahydro-isoquinoline derivatives, preparation and therapeutic use thereof |
| CN102787092B (zh) * | 2011-05-17 | 2018-01-09 | 李晖 | 培养基、细胞培养用试剂盒及细胞培养方法 |
| MX2015011125A (es) * | 2013-03-05 | 2015-11-11 | Hoffmann La Roche | Compuestos antivirales. |
| AU2016270373A1 (en) | 2015-06-05 | 2018-01-04 | Vertex Pharmaceuticals Incorporated | Triazoles for the treatment of demyelinating diseases |
| BR112021026618A2 (pt) * | 2019-06-28 | 2022-06-07 | Shanghai Pharmaceuticals Holding Co Ltd | Composto de pirazolpirimidina, método de preparação do mesmo e aplicações do mesmo |
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| US5637592A (en) * | 1994-07-12 | 1997-06-10 | Janssen Pharmaceutica N.V. | Acyl derivatives of azolones |
| GB2338957B (en) * | 1997-02-19 | 2001-08-01 | Berlex Lab | N-heterocyclic derivatives as nos inhibitors |
| RU2340611C2 (ru) * | 2000-09-15 | 2008-12-10 | Вертекс Фармасьютикалз Инкорпорейтед | Производные пиразола, используемые в качестве ингибиторов протеинкиназы |
| MXPA03005777A (es) * | 2000-12-22 | 2005-02-14 | Johnson & Johnson | Derivados de triazol diaminas sustituidos como inhibidores de cinasa. |
| DE10123586A1 (de) | 2001-05-08 | 2002-11-28 | Schering Ag | 3,5-Diamino-1,2,4-triazole als Kinase Inhibitoren |
| TWI335913B (en) * | 2002-11-15 | 2011-01-11 | Vertex Pharma | Diaminotriazoles useful as inhibitors of protein kinases |
| WO2005013982A1 (en) | 2003-08-06 | 2005-02-17 | Vertex Pharmaceuticals Incorporated | Aminotriazole compounds useful as inhibitors of protein kinases |
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2005
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- 2005-10-21 RU RU2007118687/04A patent/RU2393155C2/ru not_active IP Right Cessation
- 2005-10-21 PL PL05815914T patent/PL1811998T3/pl unknown
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- 2005-10-21 KR KR1020077011405A patent/KR20070085407A/ko not_active Withdrawn
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2007
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2011
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Also Published As
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| ES2352453T3 (es) | 2011-02-18 |
| RU2007118687A (ru) | 2008-11-27 |
| CN101072556A (zh) | 2007-11-14 |
| EP1811998A1 (en) | 2007-08-01 |
| AU2005299816A2 (en) | 2006-05-04 |
| NZ555088A (en) | 2009-08-28 |
| RU2393155C2 (ru) | 2010-06-27 |
| CY1111197T1 (el) | 2015-06-11 |
| MX2007004841A (es) | 2007-05-21 |
| US20070270410A1 (en) | 2007-11-22 |
| ATE485042T1 (de) | 2010-11-15 |
| AR054088A1 (es) | 2007-06-06 |
| BRPI0517435A (pt) | 2008-10-07 |
| DK1811998T3 (da) | 2011-02-14 |
| SI1811998T1 (sl) | 2011-01-31 |
| ZA200703950B (en) | 2008-07-30 |
| CA2584752A1 (en) | 2006-05-04 |
| TW200630090A (en) | 2006-09-01 |
| IL182664A0 (en) | 2007-09-20 |
| NO20072567L (no) | 2007-07-17 |
| JP2008517923A (ja) | 2008-05-29 |
| DE602005024293D1 (de) | 2010-12-02 |
| PT1811998E (pt) | 2010-12-23 |
| PL1811998T3 (pl) | 2011-05-31 |
| AU2005299816B2 (en) | 2011-09-01 |
| WO2006047256A1 (en) | 2006-05-04 |
| HRP20100715T1 (hr) | 2011-02-28 |
| JP5085330B2 (ja) | 2012-11-28 |
| AU2005299816A1 (en) | 2006-05-04 |
| EP1811998B1 (en) | 2010-10-20 |
| US7645775B2 (en) | 2010-01-12 |
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