KR20070085407A - 단백질 키나아제의 억제제로서 유용한 트리아졸 - Google Patents
단백질 키나아제의 억제제로서 유용한 트리아졸 Download PDFInfo
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- KR20070085407A KR20070085407A KR1020077011405A KR20077011405A KR20070085407A KR 20070085407 A KR20070085407 A KR 20070085407A KR 1020077011405 A KR1020077011405 A KR 1020077011405A KR 20077011405 A KR20077011405 A KR 20077011405A KR 20070085407 A KR20070085407 A KR 20070085407A
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- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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| US62127004P | 2004-10-21 | 2004-10-21 | |
| US60/621,270 | 2004-10-21 |
Publications (1)
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| KR20070085407A true KR20070085407A (ko) | 2007-08-27 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20100298557A1 (en) | 2006-12-28 | 2010-11-25 | Taisho Pharmaceutical Co., Ltd | Pyrazolopyrimidine compound |
| ES2672172T3 (es) | 2006-12-29 | 2018-06-12 | Rigel Pharmaceuticals, Inc. | Triazoles N3-heteroarilsustituidos y triazoles N5-heteroarilsustituidos útiles como inhibidores de Axl |
| AU2016259396B2 (en) * | 2006-12-29 | 2018-11-08 | Rigel Pharmaceuticals, Inc. | Substituted triazoles useful as Axl inhibitors |
| AU2014200824B2 (en) * | 2006-12-29 | 2016-12-15 | Rigel Pharmaceuticals, Inc. | Substituted triazoles useful as Axl inhibitors |
| WO2008083353A1 (en) | 2006-12-29 | 2008-07-10 | Rigel Pharmaceuticals, Inc. | Bicyclic aryl and bicyclic heteroaryl substituted triazoles useful as axl inhibitors |
| EP2079736B1 (en) | 2006-12-29 | 2017-10-18 | Rigel Pharmaceuticals, Inc. | Substituted triazoles useful as axl inhibitors |
| EP2114955B1 (en) | 2006-12-29 | 2013-02-13 | Rigel Pharmaceuticals, Inc. | Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors |
| JO2784B1 (en) | 2007-10-18 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | 5,3,1 - Triazole substitute derivative |
| JP2011500625A (ja) | 2007-10-18 | 2011-01-06 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | トリ置換された１，２，４−トリアゾール |
| AR070936A1 (es) | 2008-03-19 | 2010-05-12 | Janssen Pharmaceutica Nv | 1,2,4 -triazoles trisustituidos |
| JP5486591B2 (ja) | 2008-05-09 | 2014-05-07 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | アセチルコリン受容体モジュレーターとしての三置換ピラゾール |
| US8431594B2 (en) | 2008-07-09 | 2013-04-30 | Rigel Pharmaceuticals, Inc. | Bridged bicyclic heteroaryl substituted triazoles useful as AXL inhibitors |
| ES2555982T3 (es) | 2009-01-15 | 2016-01-12 | Rigel Pharmaceuticals, Inc. | Inhibidores de la proteína quinasa C y usos de los mismos |
| SG172997A1 (en) | 2009-01-16 | 2011-08-29 | Rigel Pharmaceuticals Inc | Axl inhibitors for use in combination therapy for preventing, treating or managing metastatic cancer |
| WO2011143155A1 (en) | 2010-05-11 | 2011-11-17 | Sanofi | Substituted n-heteroaryl tetrahydro-isoquinoline derivatives, preparation and therapeutic use thereof |
| WO2011143162A1 (en) | 2010-05-11 | 2011-11-17 | Sanofi | Substituted n-heteroaryl bipyrrolidine carboxamides, preparation and therapeutic use thereof |
| JP5833105B2 (ja) | 2010-05-11 | 2015-12-16 | サノフイ | 置換ｎ−ヘテロアリールスピロラクタムビピロリジン類、その製造及び治療的使用 |
| EP2569297A1 (en) | 2010-05-11 | 2013-03-20 | Sanofi | Substituted n-heterocycloalkyl bipyrrolidinylphenyl amide derivatives, preparation and therapeutic use thereof |
| AR083718A1 (es) | 2010-05-11 | 2013-03-20 | Sanofi Aventis | Fenil cicloalquil pirrolidina (piperidina) espirolactamas y amidas sustituidas, preparacion y uso terapeutico de las mismas |
| TW201206889A (en) | 2010-05-11 | 2012-02-16 | Sanofi Aventis | Substituted N-alkyl and N-acyl tetrahydro-isoquinoline derivatives, preparation and therapeutic use thereof |
| CN107142237B (zh) * | 2011-05-17 | 2021-03-02 | 深圳涌泰生物科技有限公司 | 培养基、细胞培养用试剂盒及细胞培养方法 |
| CA2900892A1 (en) | 2013-03-05 | 2014-09-12 | F. Hoffmann-La Roche Ag | Antiviral compounds |
| AU2016270373A1 (en) | 2015-06-05 | 2018-01-04 | Vertex Pharmaceuticals Incorporated | Triazoles for the treatment of demyelinating diseases |
| KR20220042127A (ko) * | 2019-06-28 | 2022-04-04 | 상하이 파마슈티컬스 홀딩 컴퍼니 리미티드 | 피라졸로피리미딘 화합물, 그의 제조 방법 및 그의 응용 |
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| US5637592A (en) * | 1994-07-12 | 1997-06-10 | Janssen Pharmaceutica N.V. | Acyl derivatives of azolones |
| PL335235A1 (en) * | 1997-02-19 | 2000-04-10 | Berlex Lab | N-heterocyclic derivatives as nos inhibitors |
| RU2340611C2 (ru) * | 2000-09-15 | 2008-12-10 | Вертекс Фармасьютикалз Инкорпорейтед | Производные пиразола, используемые в качестве ингибиторов протеинкиназы |
| DE60120494T2 (de) * | 2000-12-22 | 2006-12-21 | Ortho-Mcneil Pharmaceutical, Inc. | Substituieten triazoldiamin derivaten und ihre verwendung als kinase inhibitoren |
| DE10123586A1 (de) * | 2001-05-08 | 2002-11-28 | Schering Ag | 3,5-Diamino-1,2,4-triazole als Kinase Inhibitoren |
| CL2003002353A1 (es) * | 2002-11-15 | 2005-02-04 | Vertex Pharma | Compuestos derivados de diaminotriazoles, inhibidores d ela proteina quinasa; composicion farmaceutica; procedimiento de preparacion; y su uso del compuesto en el tratamiento de enfermedades de desordenes alergicos, proliferacion, autoinmunes, condic |
| WO2005013982A1 (en) * | 2003-08-06 | 2005-02-17 | Vertex Pharmaceuticals Incorporated | Aminotriazole compounds useful as inhibitors of protein kinases |
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2005
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- 2005-10-21 RU RU2007118687/04A patent/RU2393155C2/ru not_active IP Right Cessation
- 2005-10-21 TW TW094137050A patent/TW200630090A/zh unknown
- 2005-10-21 ES ES05815914T patent/ES2352453T3/es not_active Expired - Lifetime
- 2005-10-21 PT PT05815914T patent/PT1811998E/pt unknown
- 2005-10-21 NZ NZ555088A patent/NZ555088A/en not_active IP Right Cessation
- 2005-10-21 DE DE602005024293T patent/DE602005024293D1/de not_active Expired - Lifetime
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- 2005-10-21 HR HR20100715T patent/HRP20100715T1/hr unknown
- 2005-10-21 MX MX2007004841A patent/MX2007004841A/es unknown
- 2005-10-21 CA CA002584752A patent/CA2584752A1/en not_active Abandoned
- 2005-10-21 ZA ZA200703950A patent/ZA200703950B/en unknown
- 2005-10-21 AU AU2005299816A patent/AU2005299816B2/en not_active Ceased
- 2005-10-21 BR BRPI0517435-0A patent/BRPI0517435A/pt not_active IP Right Cessation
- 2005-10-21 KR KR1020077011405A patent/KR20070085407A/ko not_active Withdrawn
- 2005-10-21 WO PCT/US2005/037830 patent/WO2006047256A1/en not_active Ceased
- 2005-10-21 JP JP2007538052A patent/JP5085330B2/ja not_active Expired - Fee Related
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2007
- 2007-04-19 IL IL182664A patent/IL182664A0/en unknown
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2011
- 2011-01-04 CY CY20111100005T patent/CY1111197T1/el unknown
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| ES2352453T3 (es) | 2011-02-18 |
| US7645775B2 (en) | 2010-01-12 |
| CY1111197T1 (el) | 2015-06-11 |
| EP1811998B1 (en) | 2010-10-20 |
| US20070270410A1 (en) | 2007-11-22 |
| DE602005024293D1 (de) | 2010-12-02 |
| IL182664A0 (en) | 2007-09-20 |
| BRPI0517435A (pt) | 2008-10-07 |
| NO20072567L (no) | 2007-07-17 |
| WO2006047256A1 (en) | 2006-05-04 |
| DK1811998T3 (da) | 2011-02-14 |
| JP2008517923A (ja) | 2008-05-29 |
| ZA200703950B (en) | 2008-07-30 |
| PT1811998E (pt) | 2010-12-23 |
| AU2005299816B2 (en) | 2011-09-01 |
| NZ555088A (en) | 2009-08-28 |
| CA2584752A1 (en) | 2006-05-04 |
| HRP20100715T1 (hr) | 2011-02-28 |
| AU2005299816A2 (en) | 2006-05-04 |
| AR054088A1 (es) | 2007-06-06 |
| ATE485042T1 (de) | 2010-11-15 |
| EP1811998A1 (en) | 2007-08-01 |
| RU2393155C2 (ru) | 2010-06-27 |
| RU2007118687A (ru) | 2008-11-27 |
| PL1811998T3 (pl) | 2011-05-31 |
| TW200630090A (en) | 2006-09-01 |
| MX2007004841A (es) | 2007-05-21 |
| JP5085330B2 (ja) | 2012-11-28 |
| AU2005299816A1 (en) | 2006-05-04 |
| CN101072556A (zh) | 2007-11-14 |
| SI1811998T1 (sl) | 2011-01-31 |
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