KR20070030331A - 신경 친화성 타크로리무스 유사체 - Google Patents
신경 친화성 타크로리무스 유사체 Download PDFInfo
- Publication number
- KR20070030331A KR20070030331A KR1020077003889A KR20077003889A KR20070030331A KR 20070030331 A KR20070030331 A KR 20070030331A KR 1020077003889 A KR1020077003889 A KR 1020077003889A KR 20077003889 A KR20077003889 A KR 20077003889A KR 20070030331 A KR20070030331 A KR 20070030331A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- disease
- formula
- nerve
- tacrolimus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Packages (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25850000P | 2000-12-29 | 2000-12-29 | |
| US60/258,500 | 2000-12-29 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020037008787A Division KR100794204B1 (ko) | 2000-12-29 | 2001-12-31 | 신경 친화성 타크로리무스 유사체 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20070030331A true KR20070030331A (ko) | 2007-03-15 |
Family
ID=22980816
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077003889A KR20070030331A (ko) | 2000-12-29 | 2001-12-31 | 신경 친화성 타크로리무스 유사체 |
| KR1020037008787A KR100794204B1 (ko) | 2000-12-29 | 2001-12-31 | 신경 친화성 타크로리무스 유사체 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020037008787A KR100794204B1 (ko) | 2000-12-29 | 2001-12-31 | 신경 친화성 타크로리무스 유사체 |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1353671A4 (pt) |
| JP (1) | JP2004527472A (pt) |
| KR (2) | KR20070030331A (pt) |
| CN (1) | CN1293877C (pt) |
| AR (1) | AR035411A1 (pt) |
| AU (1) | AU2002231277B2 (pt) |
| BR (1) | BR0116762A (pt) |
| CA (1) | CA2433384A1 (pt) |
| CZ (1) | CZ20032060A3 (pt) |
| HU (1) | HUP0302521A3 (pt) |
| IL (1) | IL156664A0 (pt) |
| MX (1) | MXPA03005941A (pt) |
| NO (1) | NO20032913D0 (pt) |
| NZ (1) | NZ527209A (pt) |
| PL (1) | PL366301A1 (pt) |
| RU (1) | RU2288716C2 (pt) |
| WO (1) | WO2002053159A1 (pt) |
| ZA (1) | ZA200305806B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003901023A0 (en) * | 2003-03-04 | 2003-03-20 | Fujisawa Pharmaceutical Co., Ltd. | New use |
| CA2554045A1 (en) * | 2004-01-20 | 2005-07-28 | Astellas Pharma Inc. | Method for treating erectile dysfunction |
| EP1810675A1 (en) * | 2006-01-18 | 2007-07-25 | Institut Curie | Method for treating Huntington's disease by inhibiting dephosphorylation of huntingtin at S421 |
| JP2009102226A (ja) * | 2006-02-14 | 2009-05-14 | Meiji Milk Prod Co Ltd | 脊髄損傷治療剤 |
| JP5878015B2 (ja) * | 2008-07-23 | 2016-03-08 | ノバルティス アーゲー | スフィンゴシン一リン酸受容体調節因子および筋肉炎症を治療するためのその使用 |
| JP2015511242A (ja) * | 2012-02-23 | 2015-04-16 | インセルム（インスティチュート ナショナル デ ラ サンテ エ デ ラリシェルシェ メディカル） | 病変性前庭障害の治療に使用するカルシニューリン阻害剤 |
| GB201309375D0 (en) * | 2013-05-24 | 2013-07-10 | Chronos Therapeutics Ltd | Medical methods and compounds for medical use |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2799208B2 (ja) * | 1987-12-09 | 1998-09-17 | フアイソンズ・ピーエルシー | マクロ環状化合物 |
| GR1001225B (el) * | 1989-09-14 | 1993-06-30 | Fisons Plc | Νέαι μακροκυκλικαί ενώσεις και νέα μέ?οδος χρήσεως τους. |
| US5541193A (en) | 1991-09-05 | 1996-07-30 | Abbott Laboratories | Heterocycle-containing macrocyclic immunomodulators |
| GB9202196D0 (en) * | 1992-02-01 | 1992-03-18 | Fisons Plc | Method of treatment |
| GB9218027D0 (en) * | 1992-08-25 | 1992-10-14 | Fisons Plc | Novel method of treatment |
| GB9917158D0 (en) * | 1999-07-21 | 1999-09-22 | Fujisawa Pharmaceutical Co | New use |
-
2001
- 2001-12-27 AR ARP010106058A patent/AR035411A1/es unknown
- 2001-12-31 BR BR0116762-6A patent/BR0116762A/pt not_active Application Discontinuation
- 2001-12-31 CA CA002433384A patent/CA2433384A1/en not_active Abandoned
- 2001-12-31 PL PL01366301A patent/PL366301A1/xx not_active Application Discontinuation
- 2001-12-31 HU HU0302521A patent/HUP0302521A3/hu unknown
- 2001-12-31 IL IL15666401A patent/IL156664A0/xx unknown
- 2001-12-31 RU RU2003123493/15A patent/RU2288716C2/ru not_active IP Right Cessation
- 2001-12-31 JP JP2002554109A patent/JP2004527472A/ja not_active Ceased
- 2001-12-31 CN CNB018228860A patent/CN1293877C/zh not_active Expired - Fee Related
- 2001-12-31 AU AU2002231277A patent/AU2002231277B2/en not_active Ceased
- 2001-12-31 CZ CZ20032060A patent/CZ20032060A3/cs unknown
- 2001-12-31 KR KR1020077003889A patent/KR20070030331A/ko not_active Application Discontinuation
- 2001-12-31 NZ NZ527209A patent/NZ527209A/en unknown
- 2001-12-31 EP EP01991558A patent/EP1353671A4/en not_active Withdrawn
- 2001-12-31 MX MXPA03005941A patent/MXPA03005941A/es active IP Right Grant
- 2001-12-31 WO PCT/US2001/050419 patent/WO2002053159A1/en active IP Right Grant
- 2001-12-31 KR KR1020037008787A patent/KR100794204B1/ko not_active IP Right Cessation
-
2003
- 2003-06-24 NO NO20032913A patent/NO20032913D0/no not_active Application Discontinuation
- 2003-07-28 ZA ZA2003/05806A patent/ZA200305806B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002231277B2 (en) | 2006-11-30 |
| IL156664A0 (en) | 2004-01-04 |
| ZA200305806B (en) | 2005-01-26 |
| EP1353671A4 (en) | 2004-07-14 |
| CN1538843A (zh) | 2004-10-20 |
| HUP0302521A2 (hu) | 2003-11-28 |
| KR20040007431A (ko) | 2004-01-24 |
| CA2433384A1 (en) | 2002-07-11 |
| EP1353671A1 (en) | 2003-10-22 |
| JP2004527472A (ja) | 2004-09-09 |
| MXPA03005941A (es) | 2005-02-14 |
| NO20032913D0 (no) | 2003-06-24 |
| NZ527209A (en) | 2005-09-30 |
| PL366301A1 (en) | 2005-01-24 |
| KR100794204B1 (ko) | 2008-01-14 |
| WO2002053159A1 (en) | 2002-07-11 |
| AR035411A1 (es) | 2004-05-26 |
| CZ20032060A3 (cs) | 2004-01-14 |
| CN1293877C (zh) | 2007-01-10 |
| BR0116762A (pt) | 2004-08-10 |
| RU2288716C2 (ru) | 2006-12-10 |
| HUP0302521A3 (en) | 2007-03-28 |
| RU2003123493A (ru) | 2005-01-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Gaviria et al. | Neuroprotective effects of a novel NMDA antagonist, Gacyclidine, after experimental contusive spinal cord injury in adult rats | |
| Gold et al. | The immunosuppressant FK506 increases functional recovery and nerve regeneration following peripheral nerve injury | |
| Geisler et al. | GM-1 ganglioside in human spinal cord injury | |
| JP2000514420A (ja) | 末梢または中枢神経障害およびサイトカイン過剰産生の治療のためのｋ―２５２ａ誘導体の使用 | |
| DE69635754T9 (de) | Medikamente zur verhinderung von eingriffsbedingter stenose als folge von nicht-bypass invasiver eingriffe | |
| CN115397443A (zh) | 包含疼痛调节剂的干细胞来源的外排体及其用途 | |
| KR100794204B1 (ko) | 신경 친화성 타크로리무스 유사체 | |
| JPWO2019124483A1 (ja) | 神経系疾患治療剤 | |
| AU2002231277A1 (en) | Neurotrophic tacrolimus analogs | |
| JP6835738B2 (ja) | 軸索障害の処置用のパルテノライドおよびその誘導体 | |
| EP1207878B1 (de) | Behandlung der migräne durch verabreichung von alpha-liponsäure oder derivaten derselben | |
| US20040077676A1 (en) | Neurotrophic tacrolimus analogs | |
| US6075045A (en) | Method of treating paralysis of the extremities caused by cerebral infarction | |
| JP2009504636A (ja) | 血漿または血清を含む神経損傷治療用の医薬組成物 | |
| Kárová et al. | Tissue engineering and regenerative medicine in spinal cord injury repair | |
| CA2455896A1 (en) | Use of compounds for treating conditions resulting from injury to the corneal nerve after lasik and other ocular surgeries or trauma | |
| Brailowsky et al. | Acceleration of functional recovery from motor cortex ablation by two Ginkgo biloba extracts in rats | |
| Itoh et al. | The effect of neurotrophic pyrimidine heterocyclic compounds, MS-818 and MS-430, on the regeneration of injured peripheral nerves | |
| US6476001B1 (en) | Facilitation of repair of neural injury with CM101/GBS toxin | |
| CN117530937B (zh) | Idebenone在制备预防和/或治疗肌腱损伤的药物中的应用 | |
| US20040162315A1 (en) | Use of compounds for treating conditions resulting from injury to the corneal nerve after LASIK and other ocular surgeries or trauma | |
| KR100479362B1 (ko) | 중추또는말초신경계장애및싸이토카인과잉생산치료를위한k-252a유도체 | |
| US20010051652A1 (en) | Method of treating paralysis of the extremities caused by cerebral infarction | |
| EP3362059B1 (en) | New combination therapies for treating neurological damage | |
| US6852496B1 (en) | Methods of screening for agents that promote nerve cell growth |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A107 | Divisional application of patent | ||
| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| AMND | Amendment | ||
| E601 | Decision to refuse application | ||
| AMND | Amendment | ||
| J201 | Request for trial against refusal decision | ||
| E902 | Notification of reason for refusal | ||
| B601 | Maintenance of original decision after re-examination before a trial | ||
| J301 | Trial decision |
Free format text: TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20080404 Effective date: 20090227 |