GR1001225B - Νέαι μακροκυκλικαί ενώσεις και νέα μέ?οδος χρήσεως τους. - Google Patents

Νέαι μακροκυκλικαί ενώσεις και νέα μέ?οδος χρήσεως τους.

Info

Publication number
GR1001225B
GR1001225B GR900100688A GR900100688A GR1001225B GR 1001225 B GR1001225 B GR 1001225B GR 900100688 A GR900100688 A GR 900100688A GR 900100688 A GR900100688 A GR 900100688A GR 1001225 B GR1001225 B GR 1001225B
Authority
GR
Greece
Prior art keywords
application method
new application
novel macrocyclic
compositions
macrocyclic compositions
Prior art date
Application number
GR900100688A
Other languages
English (en)
Other versions
GR900100688A (en
Inventor
David Keith Donald
Mark Furber
David Norman Hardern
Paul Leff
Original Assignee
Fisons Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898920849A external-priority patent/GB8920849D0/en
Priority claimed from GB898920985A external-priority patent/GB8920985D0/en
Priority claimed from GB909006449A external-priority patent/GB9006449D0/en
Priority claimed from GB909012795A external-priority patent/GB9012795D0/en
Priority claimed from GB909014959A external-priority patent/GB9014959D0/en
Application filed by Fisons Plc filed Critical Fisons Plc
Publication of GR900100688A publication Critical patent/GR900100688A/el
Publication of GR1001225B publication Critical patent/GR1001225B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Abstract

Ενώσεις του τύπου Ι ω
GR900100688A 1989-09-14 1990-09-12 Νέαι μακροκυκλικαί ενώσεις και νέα μέ?οδος χρήσεως τους. GR1001225B (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB898920849A GB8920849D0 (en) 1989-09-14 1989-09-14 Compound
GB898920985A GB8920985D0 (en) 1989-09-15 1989-09-15 Method of treatment
GB909006449A GB9006449D0 (en) 1990-03-22 1990-03-22 Compounds
GB909012795A GB9012795D0 (en) 1990-06-08 1990-06-08 Compounds
GB909014959A GB9014959D0 (en) 1990-07-06 1990-07-06 Method of treatment

Publications (2)

Publication Number Publication Date
GR900100688A GR900100688A (en) 1992-01-20
GR1001225B true GR1001225B (el) 1993-06-30

Family

ID=27516937

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100688A GR1001225B (el) 1989-09-14 1990-09-12 Νέαι μακροκυκλικαί ενώσεις και νέα μέ?οδος χρήσεως τους.

Country Status (7)

Country Link
EP (1) EP0491797A1 (el)
JP (1) JPH05500215A (el)
KR (1) KR920702219A (el)
GR (1) GR1001225B (el)
IE (1) IE903334A1 (el)
PT (1) PT95305A (el)
WO (1) WO1991004025A1 (el)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208228A (en) * 1989-11-13 1993-05-04 Merck & Co., Inc. Aminomacrolides and derivatives having immunosuppressive activity
US5342935A (en) * 1990-06-25 1994-08-30 Merck & Co., Inc. Antagonists of immunosuppressive macrolides
US5190950A (en) * 1990-06-25 1993-03-02 Merck & Co., Inc. Antagonists of immunosuppressive macrolides
US5143918A (en) * 1990-10-11 1992-09-01 Merck & Co., Inc. Halomacrolides and derivatives having immunosuppressive activity
US5162334A (en) * 1991-05-13 1992-11-10 Merck & Co., Inc. Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity
US5250678A (en) * 1991-05-13 1993-10-05 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
US5262533A (en) * 1991-05-13 1993-11-16 Merck & Co., Inc. Amino O-aryl macrolides having immunosuppressive activity
US5565560A (en) * 1991-05-13 1996-10-15 Merck & Co., Inc. O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
US5189042A (en) * 1991-08-22 1993-02-23 Merck & Co. Inc. Fluoromacrolides having immunosuppressive activity
DE69232630T2 (de) * 1991-09-05 2003-10-09 Abbott Lab Makrocyclische immunmodulatoren
US5708002A (en) * 1991-09-05 1998-01-13 Abbott Laboratories Macrocyclic immunomodulators
ZA926812B (en) 1991-09-09 1993-04-28 Merck & Co Inc O-heteroaryl,o-alkylheteroaryl,o-alkenylheteroaryl and o-alkynylheteroaryl macrolides having immunosupressive activity
US5208241A (en) * 1991-09-09 1993-05-04 Merck & Co., Inc. N-heteroaryl, n-alkylheteroaryl, n-alkenylheteroaryl and n-alkynylheteroarylmacrolides having immunosuppressive activity
US5284877A (en) * 1992-06-12 1994-02-08 Merck & Co., Inc. Alkyl and alkenyl macrolides having immunosuppressive activity
US5284840A (en) * 1992-06-12 1994-02-08 Merck & Co., Inc. Alkylidene macrolides having immunosuppressive activity
GB9218597D0 (en) * 1992-08-25 1992-10-14 Fisons Plc Novel method of treatment
GB9218027D0 (en) * 1992-08-25 1992-10-14 Fisons Plc Novel method of treatment
US5693648A (en) * 1994-09-30 1997-12-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity
GB9917158D0 (en) * 1999-07-21 1999-09-22 Fujisawa Pharmaceutical Co New use
AR035411A1 (es) * 2000-12-29 2004-05-26 Fujisawa Pharmaceutical Co Uso de un derivado de tacrolimus para fabricar un agente neurotrofico, composiciones y articulos de fabricacion o kits que lo comprenden, metodo para fabricar un agente que lo comprende y tejidos e injertos con una celula nerviosa tratada con este compuesto
AU2003901023A0 (en) * 2003-03-04 2003-03-20 Fujisawa Pharmaceutical Co., Ltd. New use
WO2005067928A1 (en) * 2004-01-20 2005-07-28 Astellas Pharma Inc. Method for treating erectile dysfunction
NZ567540A (en) * 2005-12-22 2010-07-30 Newron Pharm Spa 2-Phenylethylamino derivatives as calcium and/or sodium channel modulators
JP2009203162A (ja) * 2006-06-05 2009-09-10 Astellas Pharma Inc マクロライド化合物の新規製造法
MX2019005504A (es) 2016-11-10 2019-08-12 Novartis Ag Potenciadores de bmp.
CA3180348A1 (en) * 2020-06-09 2021-12-16 James Wells Compound for prevention or treatment of a skin cancer or skin precancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
DE3853477T2 (de) * 1987-12-09 1995-11-09 Fisons Plc Makrozyklische verbindungen.
US4981792A (en) * 1988-06-29 1991-01-01 Merck & Co., Inc. Immunosuppressant compound
DE68921934T2 (de) * 1988-06-29 1995-10-19 Merck & Co Inc Immunsuppressives Agens.
EP0356399A3 (en) * 1988-08-26 1991-03-20 Sandoz Ag Substituted 4-azatricyclo (22.3.1.04.9) octacos-18-ene derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IE903334A1 (en) 1991-04-10
KR920702219A (ko) 1992-09-03
GR900100688A (en) 1992-01-20
WO1991004025A1 (en) 1991-04-04
JPH05500215A (ja) 1993-01-21
EP0491797A1 (en) 1992-07-01
PT95305A (pt) 1991-06-25

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