GR900100614A - Μακροκυκλικες νοσοκατασταλτικες ενωσεις. - Google Patents

Μακροκυκλικες νοσοκατασταλτικες ενωσεις.

Info

Publication number
GR900100614A
GR900100614A GR900100614A GR900100614A GR900100614A GR 900100614 A GR900100614 A GR 900100614A GR 900100614 A GR900100614 A GR 900100614A GR 900100614 A GR900100614 A GR 900100614A GR 900100614 A GR900100614 A GR 900100614A
Authority
GR
Greece
Prior art keywords
macrocyclic compounds
macrocyclic
compounds
descriptions
type
Prior art date
Application number
GR900100614A
Other languages
English (en)
Inventor
Edward Martin Cooper
Keith David Donald
Mark Furber
Norman David Hardern
Masashi Hashimoto
Chiyoshi Kasahara
Takehiko Ohkawa
Original Assignee
Fisons Plc
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898918927A external-priority patent/GB8918927D0/en
Priority claimed from GB898922653A external-priority patent/GB8922653D0/en
Priority claimed from GB909012426A external-priority patent/GB9012426D0/en
Application filed by Fisons Plc, Fujisawa Pharmaceutical Co filed Critical Fisons Plc
Publication of GR900100614A publication Critical patent/GR900100614A/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Περιγράφονται ενώσεις του τύπου Ι, ω
GR900100614A 1989-08-18 1990-08-16 Μακροκυκλικες νοσοκατασταλτικες ενωσεις. GR900100614A (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898918927A GB8918927D0 (en) 1989-08-18 1989-08-18 Compounds
GB898922653A GB8922653D0 (en) 1989-10-09 1989-10-09 Tricyclo compounds,a process for their production and a pharmaceutical composition containing the same
GB909012426A GB9012426D0 (en) 1990-06-04 1990-06-04 Tricyclo compounds,a process for their production and a pharmaceutical composition containing the same

Publications (1)

Publication Number Publication Date
GR900100614A true GR900100614A (el) 1991-12-30

Family

ID=27264646

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100614A GR900100614A (el) 1989-08-18 1990-08-16 Μακροκυκλικες νοσοκατασταλτικες ενωσεις.

Country Status (9)

Country Link
EP (1) EP0487593A1 (el)
JP (1) JPH05504944A (el)
CN (1) CN1049503A (el)
AU (1) AU6286690A (el)
GR (1) GR900100614A (el)
IE (1) IE902995A1 (el)
IL (1) IL95385A0 (el)
PT (1) PT95039A (el)
WO (1) WO1991002736A1 (el)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920700212A (ko) * 1989-06-14 1992-02-19 쟝 크라머·한스 루돌프 하우스 헤테로원자-함유 트리사이클릭 화합물
US5208228A (en) * 1989-11-13 1993-05-04 Merck & Co., Inc. Aminomacrolides and derivatives having immunosuppressive activity
MY110418A (en) * 1990-07-02 1998-05-30 Novartis Ag Heteroatoms-containing tricyclic compounds.
US5143918A (en) * 1990-10-11 1992-09-01 Merck & Co., Inc. Halomacrolides and derivatives having immunosuppressive activity
CA2107110C (en) * 1991-04-11 1996-02-20 Walter Patrick Cullen Novel immunosuppressant agent from streptomyces braegensis
NO921449L (no) * 1991-04-17 1992-10-19 American Home Prod Karbamater av rapamycin
US5162334A (en) * 1991-05-13 1992-11-10 Merck & Co., Inc. Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity
US5565560A (en) * 1991-05-13 1996-10-15 Merck & Co., Inc. O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
US5250678A (en) * 1991-05-13 1993-10-05 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
US5189042A (en) * 1991-08-22 1993-02-23 Merck & Co. Inc. Fluoromacrolides having immunosuppressive activity
JP3644957B2 (ja) * 1991-09-05 2005-05-11 アボット・ラボラトリーズ 大環式イムノモジュレーター
US5534632A (en) * 1991-09-05 1996-07-09 Abbott Laboratories Macrocyclic carbamate immunomodulators
US5708002A (en) * 1991-09-05 1998-01-13 Abbott Laboratories Macrocyclic immunomodulators
US5208241A (en) * 1991-09-09 1993-05-04 Merck & Co., Inc. N-heteroaryl, n-alkylheteroaryl, n-alkenylheteroaryl and n-alkynylheteroarylmacrolides having immunosuppressive activity
GB9125660D0 (en) * 1991-12-03 1992-01-29 Smithkline Beecham Plc Novel compound
CA2132457C (en) * 1992-03-02 1998-06-16 Kevin Koch Fluorosugar derivatives of macrolides
US5631235A (en) * 1992-03-02 1997-05-20 Pfizer, Inc. 2-Aminosugar derivatives of macrolides
CA2131372C (en) * 1992-03-02 1998-07-14 Kevin Koch Sugar derivatives of macrolides
DK0629203T3 (da) * 1992-03-02 2001-11-12 Pfizer Desosaminoderivater af makrolider som immunosuppressive midler og antifungale midler
CA2091194A1 (en) * 1992-04-08 1993-10-09 Richard D. Connell 2-oxo-ethyl derivatives as immunosuppressants
US5284877A (en) * 1992-06-12 1994-02-08 Merck & Co., Inc. Alkyl and alkenyl macrolides having immunosuppressive activity
US5284840A (en) * 1992-06-12 1994-02-08 Merck & Co., Inc. Alkylidene macrolides having immunosuppressive activity
CA2106034A1 (en) * 1992-09-24 1994-03-25 Ralph J. Russo 21-norrapamycin
US5258389A (en) * 1992-11-09 1993-11-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylrapamycin derivatives
US5310903A (en) * 1993-03-05 1994-05-10 Merck & Co., Inc. Imidazolidyl rapamycin derivatives
US5310901A (en) * 1993-03-05 1994-05-10 Merck & Co., Inc. O-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl and O-alkynlheteroarylrapamycin derivatives
US5693648A (en) * 1994-09-30 1997-12-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity
AR004480A1 (es) * 1995-04-06 1998-12-16 Amico Derin C D Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
US7186518B2 (en) * 2003-11-21 2007-03-06 Dade Behring Inc. Method and composition useful for determining FK 506
US20110104186A1 (en) 2004-06-24 2011-05-05 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
KR102109168B1 (ko) * 2018-12-11 2020-05-12 인트론바이오테크놀로지 신규 화합물 및 이를 포함하는 진균감염 치료용 약학적 조성물

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0184162A2 (en) * 1984-12-03 1986-06-11 Fujisawa Pharmaceutical Co., Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
WO1989005304A1 (en) * 1987-12-09 1989-06-15 Fisons Plc Macrocyclic compounds
EP0349061A2 (en) * 1988-06-29 1990-01-03 Merck & Co. Inc. Immunosuppressant agent
EP0349049A2 (en) * 1988-06-29 1990-01-03 Merck & Co. Inc. Immunosuppressant compound
EP0353678A2 (en) * 1988-08-01 1990-02-07 Fujisawa Pharmaceutical Co., Ltd. FR-901154 and FR-901155 substances, a process for their production
EP0356399A2 (en) * 1988-08-26 1990-02-28 Sandoz Ag Substituted 4-azatricyclo (22.3.1.04.9) octacos-18-ene derivatives, their preparation and pharmaceutical compositions containing them

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0184162A2 (en) * 1984-12-03 1986-06-11 Fujisawa Pharmaceutical Co., Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
WO1989005304A1 (en) * 1987-12-09 1989-06-15 Fisons Plc Macrocyclic compounds
EP0349061A2 (en) * 1988-06-29 1990-01-03 Merck & Co. Inc. Immunosuppressant agent
EP0349049A2 (en) * 1988-06-29 1990-01-03 Merck & Co. Inc. Immunosuppressant compound
EP0353678A2 (en) * 1988-08-01 1990-02-07 Fujisawa Pharmaceutical Co., Ltd. FR-901154 and FR-901155 substances, a process for their production
EP0356399A2 (en) * 1988-08-26 1990-02-28 Sandoz Ag Substituted 4-azatricyclo (22.3.1.04.9) octacos-18-ene derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IL95385A0 (en) 1991-06-30
IE902995A1 (en) 1991-02-27
EP0487593A1 (en) 1992-06-03
CN1049503A (zh) 1991-02-27
PT95039A (pt) 1991-04-18
WO1991002736A1 (en) 1991-03-07
JPH05504944A (ja) 1993-07-29
AU6286690A (en) 1991-04-03

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