ES2015047B3 - Nuevos derivados de 18-fenilestrano. - Google Patents

Nuevos derivados de 18-fenilestrano.

Info

Publication number
ES2015047B3
ES2015047B3 ES87201258T ES87201258T ES2015047B3 ES 2015047 B3 ES2015047 B3 ES 2015047B3 ES 87201258 T ES87201258 T ES 87201258T ES 87201258 T ES87201258 T ES 87201258T ES 2015047 B3 ES2015047 B3 ES 2015047B3
Authority
ES
Spain
Prior art keywords
fenilestrano
new derivatives
derivatives
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87201258T
Other languages
English (en)
Inventor
Jongh Hendrik Paul De
Den Heuvel Martinus Johannes Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Application granted granted Critical
Publication of ES2015047B3 publication Critical patent/ES2015047B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES87201258T 1986-07-23 1987-07-02 Nuevos derivados de 18-fenilestrano. Expired - Lifetime ES2015047B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8601903 1986-07-23

Publications (1)

Publication Number Publication Date
ES2015047B3 true ES2015047B3 (es) 1990-08-01

Family

ID=19848343

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87201258T Expired - Lifetime ES2015047B3 (es) 1986-07-23 1987-07-02 Nuevos derivados de 18-fenilestrano.

Country Status (15)

Country Link
US (1) US4808710A (es)
EP (1) EP0254341B1 (es)
JP (1) JPS6335595A (es)
KR (1) KR880001693A (es)
CN (1) CN87106126A (es)
AU (1) AU598836B2 (es)
CA (1) CA1284318C (es)
DE (1) DE3761308D1 (es)
DK (1) DK383887A (es)
ES (1) ES2015047B3 (es)
FI (1) FI84274C (es)
GR (1) GR3001005T3 (es)
NZ (1) NZ221019A (es)
PT (1) PT85395B (es)
ZA (1) ZA874863B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992485A (en) * 1988-10-11 1991-02-12 The Dow Chemical Company Microporous peek membranes and the preparation thereof
DE3921059A1 (de) * 1989-06-23 1991-01-10 Schering Ag 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel
ZA929315B (en) * 1991-12-20 1993-05-24 Akzo Nv 17-spirofuran-3'-ylidene steroids.
US6900193B1 (en) * 1996-05-01 2005-05-31 The United States Of America As Represented By The Department Of Health And Human Services Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
PT900234E (pt) * 1996-05-01 2000-12-29 Us Gov Health & Human Serv Derivados de progesterona substituidos em 21 que podem ser utilizados como novos agentes antiprogestativos
AU2004217988C1 (en) * 2003-02-28 2010-06-03 Southwest Foundation For Biomedical Research Method for preparing 17 alpha-acetoxy-11beta-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione, intermediates thereof, and methods for the preparation of such intermediates
EP1704161A4 (en) 2004-01-07 2011-06-08 Endorech Inc ON HELIX 12 OBJECTIVE STEROIDAL PHARMACEUTICAL PRODUCTS
US7709516B2 (en) 2005-06-17 2010-05-04 Endorecherche, Inc. Helix 12 directed non-steroidal antiandrogens
EP2576582B1 (en) 2010-05-26 2019-09-18 Corcept Therapeutics, Inc. Treatment of muscular dystrophy
CN107530435A (zh) 2015-03-02 2018-01-02 科赛普特治疗学股份有限公司 使用糖皮质激素受体拮抗剂和生长抑素治疗acth分泌型肿瘤
CN107530339B (zh) 2015-03-30 2021-03-16 科赛普特治疗学股份有限公司 糖皮质激素受体拮抗剂联合糖皮质激素用于治疗肾上腺功能不全
MX383318B (es) 2015-08-13 2025-03-13 Corcept Therapeutics Inc Metodo para diagnosticar de manera diferencial el sindrome de cushing dependiente de la corticotropina.
KR102197526B1 (ko) 2016-01-19 2020-12-31 코어셉트 쎄라퓨틱스 인코포레이티드 이소성 쿠싱 증후군의 감별 진단
US10413540B2 (en) 2017-03-31 2019-09-17 Corcept Therapeutics, Inc. Glucocorticoid receptor modulators to treat cervical cancer
MX393313B (es) 2017-06-20 2025-03-24 Corcept Therapeutics Inc Metodos de tratamiento de tumores neuroepiteliales usando moduladores selectivos del receptor de glucocorticoide.
EP3941460B1 (en) 2019-03-18 2025-10-15 Nieman, Lynnette K. Mifepristone for use in improving insulin sensitivity
EP4263807A2 (en) 2020-12-18 2023-10-25 Instil Bio (Uk) Limited Processing of tumor infiltrating lymphocytes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1255345A (en) * 1916-05-20 1918-02-05 Arthur L Shaw Conveyer.
US3100204A (en) * 1960-04-20 1963-08-06 Merck & Co Inc Haloethisterone compounds
US3074978A (en) * 1961-01-11 1963-01-22 Roussel Uclaf Process for the preparation of 13beta-n-propyl-delta4-gonene-17beta-ol-3-one and the intermediates in the preparation thereof
US3177205A (en) * 1963-03-01 1965-04-06 Syntex Corp 19-lower-alkyl-10alpha-derivatives of cortical hormones
JPS4118820Y1 (es) * 1965-09-22 1966-09-02
BE697838A (es) * 1966-11-11 1967-10-02
US3725439A (en) * 1971-01-07 1973-04-03 Merck & Co Inc 13-carbocyclic-3-keto-4-gonenes
US4167517A (en) * 1976-06-14 1979-09-11 Veb Jenapharm Gona-4,9(10)-dienes and process of producing the same
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained

Also Published As

Publication number Publication date
PT85395B (pt) 1990-04-30
DK383887A (da) 1988-01-24
KR880001693A (ko) 1988-04-26
AU7596987A (en) 1988-01-28
CA1284318C (en) 1991-05-21
FI84274B (fi) 1991-07-31
GR3001005T3 (en) 1991-12-30
EP0254341A1 (en) 1988-01-27
AU598836B2 (en) 1990-07-05
JPS6335595A (ja) 1988-02-16
PT85395A (en) 1987-08-01
CN87106126A (zh) 1988-05-11
FI873193A0 (fi) 1987-07-20
DE3761308D1 (de) 1990-02-08
NZ221019A (en) 1989-12-21
US4808710A (en) 1989-02-28
DK383887D0 (da) 1987-07-22
EP0254341B1 (en) 1990-01-03
FI84274C (fi) 1991-11-11
FI873193A7 (fi) 1988-01-24
ZA874863B (en) 1988-01-13

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