DK691287D0 - 5-floururacilderivater - Google Patents
5-floururacilderivaterInfo
- Publication number
- DK691287D0 DK691287D0 DK691287A DK691287A DK691287D0 DK 691287 D0 DK691287 D0 DK 691287D0 DK 691287 A DK691287 A DK 691287A DK 691287 A DK691287 A DK 691287A DK 691287 D0 DK691287 D0 DK 691287D0
- Authority
- DK
- Denmark
- Prior art keywords
- floururacil
- derivatives
- floururacil derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10128586 | 1986-04-30 | ||
| JP10128586 | 1986-04-30 | ||
| JP4575487 | 1987-02-27 | ||
| JP4575487 | 1987-02-27 | ||
| JP8700275 | 1987-04-30 | ||
| PCT/JP1987/000275 WO1987006582A1 (fr) | 1986-04-30 | 1987-04-30 | Derives de 5-fluorouracyle |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK691287D0 true DK691287D0 (da) | 1987-12-29 |
| DK691287A DK691287A (da) | 1988-02-19 |
| DK166088B DK166088B (da) | 1993-03-08 |
| DK166088C DK166088C (da) | 1993-08-23 |
Family
ID=26385819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK691287A DK166088C (da) | 1986-04-30 | 1987-12-29 | 2'-deoxy-5-fluoruridinderivater, fremgangsmaade til fremstilling deraf, anticancermidler indeholdende saadanne forbindelser og anvendelse af saadanne forbindelser til fremstilling af anticancermidler |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5047521A (da) |
| EP (1) | EP0247381B1 (da) |
| JP (1) | JPH07103112B2 (da) |
| KR (1) | KR950002161B1 (da) |
| DE (1) | DE3786834T2 (da) |
| DK (1) | DK166088C (da) |
| ES (1) | ES2058073T3 (da) |
| GB (1) | GB2200352B (da) |
| WO (1) | WO1987006582A1 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4864021A (en) * | 1984-10-30 | 1989-09-05 | Otsuka Pharmaceutical Co., Ltd. | 5-fluorouracil derivatives |
| AU610913B2 (en) * | 1987-07-31 | 1991-05-30 | Taiho Pharmaceutical Co., Ltd. | 2'-deoxy-5-fluorouridine derivatives |
| US4992534A (en) * | 1987-08-12 | 1991-02-12 | Otsuka Pharmaceutical Co., Ltd. | 3'-O-,5'-O-derivatives of 2'-deoxy-5-fluorouridine |
| CN1753873A (zh) * | 2003-02-22 | 2006-03-29 | 默克专利股份有限公司 | 作为液晶的氰基吡啶酮衍生物 |
| CA2526289A1 (en) * | 2003-05-20 | 2004-12-02 | Aronex Pharmaceuticals, Inc. | Combination chemotherapy comprising 5-fluorouracil or a derivative thereof and a liposomal platinum complex |
| JP2007077109A (ja) * | 2005-09-16 | 2007-03-29 | Tokyo Institute Of Technology | ヌクレオシド誘導体及びその製造方法 |
| US7561776B2 (en) * | 2005-11-29 | 2009-07-14 | Petrospec Engineering Ltd. | Method of preventing hydrogen darkening of optic fibre |
| GB0907551D0 (en) | 2009-05-01 | 2009-06-10 | Univ Dundee | Treatment or prophylaxis of proliferative conditions |
| AU2013203591B2 (en) * | 2009-05-01 | 2017-01-19 | University Court Of The University Of Dundee | Treatment or prophylaxis of proliferative conditions |
| WO2011052554A1 (ja) * | 2009-10-27 | 2011-05-05 | Ｄｅｌｔａ－Ｆｌｙ Ｐｈａｒｍａ株式会社 | 新規５－フルオロウラシル誘導体 |
| CA3091027A1 (en) | 2018-02-02 | 2019-08-08 | Maverix Oncology, Inc. | Small molecule drug conjugates of gemcitabine monophosphate |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4124765A (en) * | 1975-05-13 | 1978-11-07 | Ono Pharmaceutical Co., Ltd. | 5-Fluorouracil derivatives |
| JPS6011704B2 (ja) * | 1976-07-30 | 1985-03-27 | 大鵬薬品工業株式会社 | ５−フルオルウラシル誘導体の製造法 |
| JPS5379879A (en) * | 1976-12-23 | 1978-07-14 | Mitsui Toatsu Chem Inc | 1,3-substituted-5-fluorouracils and process for their preparation |
| DE2658672A1 (de) * | 1976-12-23 | 1978-06-29 | Robugen Gmbh | Neue nucleosid-verbindungen und verfahren zu ihrer herstellung |
| JPS5924999B2 (ja) * | 1978-06-10 | 1984-06-13 | 富山化学工業株式会社 | 新規な５−フルオロ−２′−デオキシ−β−ウリジン誘導体の製造法 |
| JPS5535057A (en) * | 1978-09-05 | 1980-03-11 | Funai Corp | 2'-deoxy-5-fluorouridine derivative, its preparation, and antitumor agent comprising it |
| US4340728A (en) * | 1979-11-28 | 1982-07-20 | Fuji Kagaku Kogyo Kabushiki Kaisha | Nucleoside derivatives and process for preparing same |
| DE3105111A1 (de) * | 1980-02-15 | 1981-12-24 | Funai Yakuhin Kogyo K.K., Osaka | "2 -desoxy-3',5-di-o-alkylcarbonyl-5-fluoruridin-derivate, verfahren zu ihrer herstellung, ihre verwendung zur behandlung von tumoren und antitumormittel" |
| JPS5929699A (ja) * | 1982-08-11 | 1984-02-16 | Funai Corp | ２′−デオキシ−５−フルオロウリジンのエ−テル誘導体およびその製造方法並びにこれを含有する抗腫瘍剤 |
| JPS58185522A (ja) * | 1983-02-28 | 1983-10-29 | Toyama Chem Co Ltd | 新規な５−フルオロ−２′−デオキシ−β−ウリジン誘導体 |
| JPS6061593A (ja) * | 1983-09-14 | 1985-04-09 | Taiho Yakuhin Kogyo Kk | ２’−デオキシ−５−トリフルオロメチルウリジン誘導体及びそれを含む抗腫瘍剤 |
| AU548712B2 (en) * | 1983-05-23 | 1986-01-02 | Taiho Pharmaceutical Co., Ltd. | 2:-deoxy-5-substituted uridine derivatives |
| EP0151189B1 (en) * | 1983-07-20 | 1990-01-31 | Teijin Limited | Antineoplastic agent |
| US4515618A (en) * | 1983-12-07 | 1985-05-07 | Chevron Research Company | 5-Deoxy-3-O-thienylmethyl or furylmethyl-1,2-O-alkylidene-alpha-D-xylofuranose herbicide derivatives |
| EP0180188B1 (en) * | 1984-10-30 | 1992-04-15 | Otsuka Pharmaceutical Co., Ltd. | A composition for increasing the anti-cancer activity of an anti-cancer compound |
| AU610913B2 (en) * | 1987-07-31 | 1991-05-30 | Taiho Pharmaceutical Co., Ltd. | 2'-deoxy-5-fluorouridine derivatives |
| US4992534A (en) * | 1987-08-12 | 1991-02-12 | Otsuka Pharmaceutical Co., Ltd. | 3'-O-,5'-O-derivatives of 2'-deoxy-5-fluorouridine |
| JPH02187484A (ja) * | 1989-01-13 | 1990-07-23 | Okitsumo Kk | 紙用瞬間接着剤 |
-
1987
- 1987-04-29 DE DE87106264T patent/DE3786834T2/de not_active Expired - Fee Related
- 1987-04-29 ES ES87106264T patent/ES2058073T3/es not_active Expired - Lifetime
- 1987-04-29 EP EP87106264A patent/EP0247381B1/en not_active Expired - Lifetime
- 1987-04-30 WO PCT/JP1987/000275 patent/WO1987006582A1/ja not_active Ceased
- 1987-04-30 US US07/150,407 patent/US5047521A/en not_active Expired - Fee Related
- 1987-04-30 KR KR1019870701257A patent/KR950002161B1/ko not_active Expired - Fee Related
- 1987-04-30 JP JP62-502695A patent/JPH07103112B2/ja not_active Expired - Lifetime
- 1987-04-30 GB GB8730031A patent/GB2200352B/en not_active Expired - Fee Related
- 1987-12-29 DK DK691287A patent/DK166088C/da active
Also Published As
| Publication number | Publication date |
|---|---|
| WO1987006582A1 (fr) | 1987-11-05 |
| GB8730031D0 (en) | 1988-02-03 |
| EP0247381B1 (en) | 1993-08-04 |
| US5047521A (en) | 1991-09-10 |
| ES2058073T3 (es) | 1994-11-01 |
| GB2200352A (en) | 1988-08-03 |
| DE3786834D1 (de) | 1993-09-09 |
| DK691287A (da) | 1988-02-19 |
| JPH07103112B1 (da) | 1995-11-08 |
| KR950002161B1 (ko) | 1995-03-14 |
| EP0247381A3 (en) | 1988-11-23 |
| DK166088B (da) | 1993-03-08 |
| DK166088C (da) | 1993-08-23 |
| KR880701232A (ko) | 1988-07-26 |
| EP0247381A2 (en) | 1987-12-02 |
| GB2200352B (en) | 1990-07-25 |
| JPH07103112B2 (ja) | 1995-11-08 |
| DE3786834T2 (de) | 1994-03-03 |
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