GB2072164B - 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivatives a process for the preparation of the derivatives and antitumor agents containing the derivatives - Google Patents

2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivatives a process for the preparation of the derivatives and antitumor agents containing the derivatives

Info

Publication number
GB2072164B
GB2072164B GB8104375A GB8104375A GB2072164B GB 2072164 B GB2072164 B GB 2072164B GB 8104375 A GB8104375 A GB 8104375A GB 8104375 A GB8104375 A GB 8104375A GB 2072164 B GB2072164 B GB 2072164B
Authority
GB
United Kingdom
Prior art keywords
derivatives
deoxy
alkylcarbonyl
preparation
fluorouridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8104375A
Other versions
GB2072164A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Funai Pharmaceutical Industries Ltd
Original Assignee
Funai Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1740880A external-priority patent/JPS56115799A/en
Priority claimed from JP11210280A external-priority patent/JPS5735596A/en
Priority claimed from JP55126776A external-priority patent/JPS5751000A/en
Application filed by Funai Pharmaceutical Industries Ltd filed Critical Funai Pharmaceutical Industries Ltd
Publication of GB2072164A publication Critical patent/GB2072164A/en
Application granted granted Critical
Publication of GB2072164B publication Critical patent/GB2072164B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
GB8104375A 1980-02-15 1981-02-12 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivatives a process for the preparation of the derivatives and antitumor agents containing the derivatives Expired GB2072164B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1740880A JPS56115799A (en) 1980-02-15 1980-02-15 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivative, its preparation, and antitumor agnet containing the same
JP11210280A JPS5735596A (en) 1980-08-13 1980-08-13 Ester derivative of deoxyfluorouridine
JP55126776A JPS5751000A (en) 1980-09-11 1980-09-11 Ester derivative of alkoxybenzoyldeoxyfluorouridine

Publications (2)

Publication Number Publication Date
GB2072164A GB2072164A (en) 1981-09-30
GB2072164B true GB2072164B (en) 1983-12-21

Family

ID=27281812

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8104375A Expired GB2072164B (en) 1980-02-15 1981-02-12 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivatives a process for the preparation of the derivatives and antitumor agents containing the derivatives

Country Status (7)

Country Link
AT (1) AT374203B (en)
CH (1) CH646715A5 (en)
DE (1) DE3105111A1 (en)
ES (1) ES499443A0 (en)
FR (1) FR2476086A1 (en)
GB (1) GB2072164B (en)
IT (1) IT1210989B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0082668A1 (en) * 1981-12-18 1983-06-29 Beecham Group Plc 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections
EP0129984B1 (en) * 1983-05-23 1988-03-02 Taiho Pharmaceutical Company Limited Novel 2'-deoxy-5-substituted uridine derivatives, processes for preparing the same and antitumor agent containing the same
US4864021A (en) * 1984-10-30 1989-09-05 Otsuka Pharmaceutical Co., Ltd. 5-fluorouracil derivatives
DK174238B1 (en) * 1984-10-30 2002-10-07 Otsuka Pharma Co Ltd 5-Fluorouracil derivatives, their preparation and drugs containing such compounds
ES2058073T3 (en) * 1986-04-30 1994-11-01 Otsuka Pharma Co Ltd DERIVATIVES OF 5-FLUOROURACILO.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5924999B2 (en) * 1978-06-10 1984-06-13 富山化学工業株式会社 Method for producing a novel 5-fluoro-2'-deoxy-β-uridine derivative
JPS5535057A (en) * 1978-09-05 1980-03-11 Funai Corp 2'-deoxy-5-fluorouridine derivative, its preparation, and antitumor agent comprising it

Also Published As

Publication number Publication date
AT374203B (en) 1984-03-26
IT8119758A0 (en) 1981-02-13
ES8206550A1 (en) 1982-08-16
FR2476086A1 (en) 1981-08-21
DE3105111C2 (en) 1993-08-12
DE3105111A1 (en) 1981-12-24
GB2072164A (en) 1981-09-30
IT1210989B (en) 1989-09-29
ATA69181A (en) 1983-08-15
FR2476086B1 (en) 1984-01-06
ES499443A0 (en) 1982-08-16
CH646715A5 (en) 1984-12-14

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19960212